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The map label for this gene is eptB [H]

Identifier: 194736604

GI number: 194736604

Start: 3704550

End: 3706241

Strand: Reverse

Name: eptB [H]

Synonym: SeSA_A3835

Alternate gene names: 194736604

Gene position: 3706241-3704550 (Counterclockwise)

Preceding gene: 194736179

Following gene: 194734273

Centisome position: 78.7

GC content: 52.25

Gene sequence:

>1692_bases
ATGAGATACATTAAATCGATGACGCAGCAGAAACTTAGTTTCTTGCTTGCGCTCTATATCGGTCTGTTTATGAATTGCGC
CGTGTTTTACCGCCGTTTCGGCAGTTATGCGCAAGAATTTACCATTTGGAAAGGCCTCTCCGCAGTTGTCGAACTTGGCG
CCACGGTGCTGGTCACTTTCTTCTTACTTCGTCTTCTTTCACTGTTTGGCCGACGCGTCTGGCGTGTGCTGGCCACGCTG
GTGGTGCTGTTTTCCGCTGGCGCCAGTTATTACATGACCTTCCTGAACGTGGTGATTGGCTACGGCATTATTGCGTCTGT
TATGACCACCGATATCGATCTCTCGAAAGAGGTGGTGGGGCTGCACTTCGTATTGTGGCTGATTGCCGTGAGCCTGCTTC
CGCTCATCTTTATCTGGAGTAACCACTGTCGCTACACGTTGTTGCGCCAGCTACGTACGCCGGGGCAGCGTTTTCGCAGC
GCCGCTGTAGTGGTACTCGCAGGCGTAATGGTGTGGGCGCCTATCCGCCTGCTGGATATACAGCAAAAAAAGGTTGAACG
GGCGACAGGTATCGACTTACCCAGCTATGGCGGCGTGGTGGCGAACTCCTATCTGCCTTCAAACTGGTTATCTGCGTTAG
GGCTGTATGCCTGGGCGCAGGTAGATGAGTCGTCGGACAATAATTCGTTAATAAACCCGGCCAGGAAATTTACCTATGTT
GCGCCGAAGGATGGGGATGACACCTACGTCGTTTTCATTATCGGTGAGACGACCCGTTGGGATCACATGGGGATTTTCGG
CTACGAGCGTAATACCACGCCGAAGCTGGCGCAGGAAAAAAATCTGGCGGCGTTCCGCGGCTATTCTTGCGATACCGCGA
CGAAGCTTTCTTTACGCTGTATGTTTGTACGGGAAGGCGGGGCGGATAATAACCCGCAGCGTACCTTAAAAGAGCAGAAT
GTGTTTGCCGTTCTCAAACAGCTCGGATTCAGTTCCGATCTGTACGCCATGCAGAGCGAGATGTGGTTCTATAGCAATAC
CATGGCGGATAATATCTCCTACCGCGAGCAGATCGGCGCCGAGCCGCGTAACCGTGGTAAAACGGTTGATGATATGCTGT
TGATTGATGAGATGCAGAACTCGCTTGCCCAGAACCCGGAGGGTAAGCATCTGATTATCCTGCATACTAAGGGGTCGCAT
TTTAACTATACGCAACGTTATCCGCGCAGCTACGCTCAGTGGAAGCCCGAATGTATTGGGGTCGATAGCGGCTGCACGAA
AGCGCAGATGATCAACTCTTACGATAACTCCGTGACCTATGTGGATCACTTTATTACCAGTGTGTTCGATCAGCTACGTG
ATAAAAAAGCGATTGTGTTCTACGCGGCTGACCACGGCGAGTCGATTAACGAACGTGAACATTTGCACGGTACGCCGCGC
AATATGGCGCCGCCGGAGCAATTCCGTGTTCCGATGCTGGTATGGATGTCGGATAAATATCTTGCCAGTCCGCAACATGC
GCAGATGTTCGCTCACCTGAAACAGCAGGCGGAGATCAAAGTGCCGCGTCGTCATGTGGAGCTGTACGATACGATAATGG
GCTGCCTGGGGTATACATCGCCGGATGGCGGCATTAACCAGAACAACAACTGGTGCCATATTCCCGATGCGCAGAAAGTC
GCCGCGAAGTAG

Upstream 100 bases:

>100_bases
TGGTAGACTTTCTCACATCTGCGTTAGCCGCATATTTACCTGTTTGATTAAAGAATCGTTGTACAGGTCGTTTTTATCCC
GATTCCCAGGGTTTGTTTGC

Downstream 100 bases:

>100_bases
GTTGTCTGCCGACTTTCTCGCCGATTGAATTGTATTTTGCGACTAAGGGATTGACGGGCGTGCGCCTGAGCAGTAAGATG
CGCCCGCATTCGGTGATTGG

Product: phosphoethanolamine transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 563; Mature: 563

Protein sequence:

>563_residues
MRYIKSMTQQKLSFLLALYIGLFMNCAVFYRRFGSYAQEFTIWKGLSAVVELGATVLVTFFLLRLLSLFGRRVWRVLATL
VVLFSAGASYYMTFLNVVIGYGIIASVMTTDIDLSKEVVGLHFVLWLIAVSLLPLIFIWSNHCRYTLLRQLRTPGQRFRS
AAVVVLAGVMVWAPIRLLDIQQKKVERATGIDLPSYGGVVANSYLPSNWLSALGLYAWAQVDESSDNNSLINPARKFTYV
APKDGDDTYVVFIIGETTRWDHMGIFGYERNTTPKLAQEKNLAAFRGYSCDTATKLSLRCMFVREGGADNNPQRTLKEQN
VFAVLKQLGFSSDLYAMQSEMWFYSNTMADNISYREQIGAEPRNRGKTVDDMLLIDEMQNSLAQNPEGKHLIILHTKGSH
FNYTQRYPRSYAQWKPECIGVDSGCTKAQMINSYDNSVTYVDHFITSVFDQLRDKKAIVFYAADHGESINEREHLHGTPR
NMAPPEQFRVPMLVWMSDKYLASPQHAQMFAHLKQQAEIKVPRRHVELYDTIMGCLGYTSPDGGINQNNNWCHIPDAQKV
AAK

Sequences:

>Translated_563_residues
MRYIKSMTQQKLSFLLALYIGLFMNCAVFYRRFGSYAQEFTIWKGLSAVVELGATVLVTFFLLRLLSLFGRRVWRVLATL
VVLFSAGASYYMTFLNVVIGYGIIASVMTTDIDLSKEVVGLHFVLWLIAVSLLPLIFIWSNHCRYTLLRQLRTPGQRFRS
AAVVVLAGVMVWAPIRLLDIQQKKVERATGIDLPSYGGVVANSYLPSNWLSALGLYAWAQVDESSDNNSLINPARKFTYV
APKDGDDTYVVFIIGETTRWDHMGIFGYERNTTPKLAQEKNLAAFRGYSCDTATKLSLRCMFVREGGADNNPQRTLKEQN
VFAVLKQLGFSSDLYAMQSEMWFYSNTMADNISYREQIGAEPRNRGKTVDDMLLIDEMQNSLAQNPEGKHLIILHTKGSH
FNYTQRYPRSYAQWKPECIGVDSGCTKAQMINSYDNSVTYVDHFITSVFDQLRDKKAIVFYAADHGESINEREHLHGTPR
NMAPPEQFRVPMLVWMSDKYLASPQHAQMFAHLKQQAEIKVPRRHVELYDTIMGCLGYTSPDGGINQNNNWCHIPDAQKV
AAK
>Mature_563_residues
MRYIKSMTQQKLSFLLALYIGLFMNCAVFYRRFGSYAQEFTIWKGLSAVVELGATVLVTFFLLRLLSLFGRRVWRVLATL
VVLFSAGASYYMTFLNVVIGYGIIASVMTTDIDLSKEVVGLHFVLWLIAVSLLPLIFIWSNHCRYTLLRQLRTPGQRFRS
AAVVVLAGVMVWAPIRLLDIQQKKVERATGIDLPSYGGVVANSYLPSNWLSALGLYAWAQVDESSDNNSLINPARKFTYV
APKDGDDTYVVFIIGETTRWDHMGIFGYERNTTPKLAQEKNLAAFRGYSCDTATKLSLRCMFVREGGADNNPQRTLKEQN
VFAVLKQLGFSSDLYAMQSEMWFYSNTMADNISYREQIGAEPRNRGKTVDDMLLIDEMQNSLAQNPEGKHLIILHTKGSH
FNYTQRYPRSYAQWKPECIGVDSGCTKAQMINSYDNSVTYVDHFITSVFDQLRDKKAIVFYAADHGESINEREHLHGTPR
NMAPPEQFRVPMLVWMSDKYLASPQHAQMFAHLKQQAEIKVPRRHVELYDTIMGCLGYTSPDGGINQNNNWCHIPDAQKV
AAK

Specific function: Catalyzes the addition of a phosphoethanolamine (pEtN) moiety to the outer 3-deoxy-D-manno-octulosonic acid (KDO) residue of a KDO(2)-lipid A. Phosphatidylethanolamines with one unsaturated acyl group functions as pEtN donors and the reaction releases dia

COG id: COG2194

COG function: function code R; Predicted membrane-associated, metal-dependent hydrolase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoethanolamine transferase family. EptB subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082286, Length=562, Percent_Identity=89.1459074733096, Blast_Score=1045, Evalue=0.0,
Organism=Escherichia coli, GI87082372, Length=542, Percent_Identity=25.0922509225092, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI87082223, Length=275, Percent_Identity=30.5454545454545, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1790392, Length=516, Percent_Identity=23.4496124031008, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1787035, Length=271, Percent_Identity=26.5682656826568, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR012549
- InterPro:   IPR000917 [H]

Pfam domain/function: PF08019 DUF1705; PF00884 Sulfatase [H]

EC number: NA

Molecular weight: Translated: 63988; Mature: 63988

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCCEEECCCHHHHCCC
>Mature Secondary Structure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CCCCCCCCCCEEECCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609; 7721701 [H]