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The map label for this gene is ytfL [H]

Identifier: 194736200

GI number: 194736200

Start: 4542621

End: 4543964

Strand: Reverse

Name: ytfL [H]

Synonym: SeSA_A4675

Alternate gene names: 194736200

Gene position: 4543964-4542621 (Counterclockwise)

Preceding gene: 194736802

Following gene: 194735307

Centisome position: 96.49

GC content: 50.37

Gene sequence:

>1344_bases
ATGTTAAACAGTATATTCATTATATTCTGCCTGATCGCTGTAAGTGCGTTCTTCTCCATCTCCGAGATCTCGCTTGCCGC
ATCACGTAAGATTAAACTTAAGTTATTAGCTGATGAAGGCAGTATCAACGCACAACGCGTATTGAAAATGCAGGAAAATC
CCGGCATGTTTTTCACCGTTGTGCAAATTGGCCTGAACGCCGTCGCTATTCTTGGCGGTATCGTCGGCGATGCGGCATTT
TCGCCCGCCTTTTCCGCCCTTTTCTCGCACTATATGTCGCCAGAACTCTCCGAGCAGCTGAGCTTTATTCTCTCTTTCTC
GCTGGTGACGGGGCTGTTTATCCTGTTCGCGGATTTAACCCCGAAACGCATCGGTATGATTGCGCCAGAAGCTGTGGCTT
TGCGTATCATCAACCCGATGCGCTTCTGCCTGTTCGTTTTTCGCCCGCTGGTGTGGCTGTTTAACGGCATGGCAAACAAC
ATCTTCCGCCTGTTCAAAATTCCAATGGTGCGGAAAGACGACATTACTTCTGATGATATTTACGCAGTGGTGGAAGCCGG
CGCGCTGGCGGGCGTCTTGCGCAAGCAAGAGCACGAACTGATTGAAAATGTGTTTGAACTTGAATCCCGCACCGTACCGT
CTTCCATGACGCCGCGCGAAAGTATCATCTGGTTTGATCTGCACGAAGACGAGCAAAGCCTGAAGAAAAAGGTCGCCGAA
CATCCGCACTCAAAATTTTTGGTGTGTAATGAAGATATCGACCACATCATCGGCTATGTAGACTCCAAAGATCTGCTGAA
CCGCGTGCTGGCGAACCAAAGTATGGCGCTGAATGGCGGCGTGCAAATTCGCAATACCTTGATTGTGCCGGATACGCTGA
CCCTTTCTGAGGCGCTGGAAAGTTTCAAAACGGCGGGCGAGGATTTCGCGGTCATTATGAATGAATACGCACTGGTCGTC
GGTATCATTACGCTGAACGATGTGATGACCACGCTAATGGGTGACCTGGTCGGCCAGGGACTGGAAGAGCAAATTGTGGC
ACGCGATGAAAATTCCTGGCTGGTTGACGGCGGCACGCCGATTGACGACGTCATGCGCGTGCTGGATATCGATGAGTTTC
CGCAATCCGGCAACTATGAAACCATTGGCGGCTTTATGATGTTTATGCTGCGCAAGATTCCAAAACGTACTGATTCGGTG
AAGTTTTCCGGCTACAAATTTGAAGTGGTGGATATCGACAACTACCGTATCGATCAGTTGCTGGTGACGCGTCTCGACAA
TAAAAGCAACGTACCGGCACCGAAACTGCCCGATGCGCAAGGTAAAGAAGACAGCGCGGCCTGA

Upstream 100 bases:

>100_bases
GAACTTATCGGCTCACTGCTACGAGCCGGTTTTCATTAAACGTTACCACACGGATTTATAAACTTCCCTTCCGAGGATCT
GGCGTTTCGCCGGATAAGAT

Downstream 100 bases:

>100_bases
AATCCGTTTGCCAGAAACATCAACGGCTCCTGATTCAGGAGCCGTTTTTTTTACTTTTTTAACCTACTGCATAGCACTTT
TGGTTACGCCATCTCAGTTT

Product: putative transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MLNSIFIIFCLIAVSAFFSISEISLAASRKIKLKLLADEGSINAQRVLKMQENPGMFFTVVQIGLNAVAILGGIVGDAAF
SPAFSALFSHYMSPELSEQLSFILSFSLVTGLFILFADLTPKRIGMIAPEAVALRIINPMRFCLFVFRPLVWLFNGMANN
IFRLFKIPMVRKDDITSDDIYAVVEAGALAGVLRKQEHELIENVFELESRTVPSSMTPRESIIWFDLHEDEQSLKKKVAE
HPHSKFLVCNEDIDHIIGYVDSKDLLNRVLANQSMALNGGVQIRNTLIVPDTLTLSEALESFKTAGEDFAVIMNEYALVV
GIITLNDVMTTLMGDLVGQGLEEQIVARDENSWLVDGGTPIDDVMRVLDIDEFPQSGNYETIGGFMMFMLRKIPKRTDSV
KFSGYKFEVVDIDNYRIDQLLVTRLDNKSNVPAPKLPDAQGKEDSAA

Sequences:

>Translated_447_residues
MLNSIFIIFCLIAVSAFFSISEISLAASRKIKLKLLADEGSINAQRVLKMQENPGMFFTVVQIGLNAVAILGGIVGDAAF
SPAFSALFSHYMSPELSEQLSFILSFSLVTGLFILFADLTPKRIGMIAPEAVALRIINPMRFCLFVFRPLVWLFNGMANN
IFRLFKIPMVRKDDITSDDIYAVVEAGALAGVLRKQEHELIENVFELESRTVPSSMTPRESIIWFDLHEDEQSLKKKVAE
HPHSKFLVCNEDIDHIIGYVDSKDLLNRVLANQSMALNGGVQIRNTLIVPDTLTLSEALESFKTAGEDFAVIMNEYALVV
GIITLNDVMTTLMGDLVGQGLEEQIVARDENSWLVDGGTPIDDVMRVLDIDEFPQSGNYETIGGFMMFMLRKIPKRTDSV
KFSGYKFEVVDIDNYRIDQLLVTRLDNKSNVPAPKLPDAQGKEDSAA
>Mature_447_residues
MLNSIFIIFCLIAVSAFFSISEISLAASRKIKLKLLADEGSINAQRVLKMQENPGMFFTVVQIGLNAVAILGGIVGDAAF
SPAFSALFSHYMSPELSEQLSFILSFSLVTGLFILFADLTPKRIGMIAPEAVALRIINPMRFCLFVFRPLVWLFNGMANN
IFRLFKIPMVRKDDITSDDIYAVVEAGALAGVLRKQEHELIENVFELESRTVPSSMTPRESIIWFDLHEDEQSLKKKVAE
HPHSKFLVCNEDIDHIIGYVDSKDLLNRVLANQSMALNGGVQIRNTLIVPDTLTLSEALESFKTAGEDFAVIMNEYALVV
GIITLNDVMTTLMGDLVGQGLEEQIVARDENSWLVDGGTPIDDVMRVLDIDEFPQSGNYETIGGFMMFMLRKIPKRTDSV
KFSGYKFEVVDIDNYRIDQLLVTRLDNKSNVPAPKLPDAQGKEDSAA

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=380, Percent_Identity=25.2631578947368, Blast_Score=154, Evalue=1e-37,
Organism=Escherichia coli, GI1790664, Length=447, Percent_Identity=91.7225950782998, Blast_Score=846, Evalue=0.0,
Organism=Escherichia coli, GI145693175, Length=423, Percent_Identity=23.4042553191489, Blast_Score=131, Evalue=9e-32,
Organism=Escherichia coli, GI87082033, Length=243, Percent_Identity=32.5102880658436, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788119, Length=240, Percent_Identity=27.5, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786879, Length=262, Percent_Identity=24.8091603053435, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 49748; Mature: 49748

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNSIFIIFCLIAVSAFFSISEISLAASRKIKLKLLADEGSINAQRVLKMQENPGMFFTV
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCHHHHHEECCCCCEEEEH
VQIGLNAVAILGGIVGDAAFSPAFSALFSHYMSPELSEQLSFILSFSLVTGLFILFADLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
PKRIGMIAPEAVALRIINPMRFCLFVFRPLVWLFNGMANNIFRLFKIPMVRKDDITSDDI
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
YAVVEAGALAGVLRKQEHELIENVFELESRTVPSSMTPRESIIWFDLHEDEQSLKKKVAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCHHHHHHHHHH
HPHSKFLVCNEDIDHIIGYVDSKDLLNRVLANQSMALNGGVQIRNTLIVPDTLTLSEALE
CCCCEEEEECCCHHHHHHCCCCHHHHHHHHCCCCEEECCCEEEEEEEECCCCHHHHHHHH
SFKTAGEDFAVIMNEYALVVGIITLNDVMTTLMGDLVGQGLEEQIVARDENSWLVDGGTP
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCEEECCCCC
IDDVMRVLDIDEFPQSGNYETIGGFMMFMLRKIPKRTDSVKFSGYKFEVVDIDNYRIDQL
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEECCEEEEEEECCCCHHHHH
LVTRLDNKSNVPAPKLPDAQGKEDSAA
HHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLNSIFIIFCLIAVSAFFSISEISLAASRKIKLKLLADEGSINAQRVLKMQENPGMFFTV
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCHHHHHEECCCCCEEEEH
VQIGLNAVAILGGIVGDAAFSPAFSALFSHYMSPELSEQLSFILSFSLVTGLFILFADLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
PKRIGMIAPEAVALRIINPMRFCLFVFRPLVWLFNGMANNIFRLFKIPMVRKDDITSDDI
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
YAVVEAGALAGVLRKQEHELIENVFELESRTVPSSMTPRESIIWFDLHEDEQSLKKKVAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCHHHHHHHHHH
HPHSKFLVCNEDIDHIIGYVDSKDLLNRVLANQSMALNGGVQIRNTLIVPDTLTLSEALE
CCCCEEEEECCCHHHHHHCCCCHHHHHHHHCCCCEEECCCEEEEEEEECCCCHHHHHHHH
SFKTAGEDFAVIMNEYALVVGIITLNDVMTTLMGDLVGQGLEEQIVARDENSWLVDGGTP
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCEEECCCCC
IDDVMRVLDIDEFPQSGNYETIGGFMMFMLRKIPKRTDSVKFSGYKFEVVDIDNYRIDQL
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEECCEEEEEEECCCCHHHHH
LVTRLDNKSNVPAPKLPDAQGKEDSAA
HHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]