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The map label for this gene is aroC [H]

Identifier: 194736067

GI number: 194736067

Start: 2497248

End: 2498333

Strand: Reverse

Name: aroC [H]

Synonym: SeSA_A2613

Alternate gene names: 194736067

Gene position: 2498333-2497248 (Counterclockwise)

Preceding gene: 194736282

Following gene: 194736928

Centisome position: 53.05

GC content: 58.56

Gene sequence:

>1086_bases
ATGGCAGGAAACACAATTGGACAACTCTTTCGCGTAACCACTTTCGGCGAATCACACGGGCTGGCGCTTGGGTGTATCGT
CGATGGCGTGCCGCCCGGCATCCCGTTGACGGAGGCCGATCTGCAGCACGATCTCGACAGACGCCGCCCTGGCACCTCGC
GCTATACTACCCAGCGCCGCGAACCGGATCAGGTAAAAATTCTCTCCGGCGTGTTTGATGGCGTGACGACCGGCACCAGC
ATTGGCCTGCTGATTGAAAACACCGATCAGCGCTCGCAGGACTACAGCGCGATTAAAGATGTTTTTCGTCCGGGACACGC
GGATTACACCTATGAGCAGAAATACGGCCTGCGCGATTACCGTGGCGGTGGACGTTCTTCCGCGCGTGAAACCGCGATGC
GCGTAGCGGCAGGGGCGATTGCCAAGAAATACCTGGCGGAAAAGTTCGGCATCGAAATCCGCGGCTGCCTGACCCAGATG
GGCGACATTCCGCTGGAGATTAAAGACTGGCGTCAGGTTGAGCTTAATCCGTTCTTTTGTCCCGATGCGGACAAACTTGA
CGCGCTGGACGAACTGATGCGCGCGCTGAAAAAAGAGGGTGACTCCATCGGCGCGAAAGTGACGGTGATGGCGAGCGGCG
TGCCGGCAGGGCTTGGCGAACCGGTTTTTGACCGACTGGATGCGGACATCGCCCATGCGCTGATGAGCATCAATGCGGTG
AAAGGCGTGGAGATCGGCGAAGGATTTAACGTGGTGGCGCTGCGCGGCAGCCAGAATCGCGATGAAATCACGGCGCAGGG
TTTTCAGAGCAACCACGCTGGCGGCATCCTCGGTGGCATCAGTAGCGGGCAACACATTGTGGCGCATATGGCGCTGAAAC
CTACCTCCAGCATTACCGTGCCGGGACGTACGATCAACCGGATGGGTGAAGAAGTCGAAATGATCACCAAAGGGCGCCAC
GATCCGTGTGTGGGGATTCGCGCAGTGCCGATCGCAGAAGCCATGCTGGCGATCGTGCTGATGGATCACCTGCTGCGCCA
TCGGGCACAGAATGCGGATGTAAAGACAGAGATTCCACGCTGGTAA

Upstream 100 bases:

>100_bases
TCTTTATGTTGACCAAAGCGCAGTTGCTCGCGGCCCGTGAACATTTCAATATTTATAAAGATTAAAACACGCAAACGACA
ACAACGATAACGGAGCCGTG

Downstream 100 bases:

>100_bases
GAAATGAAAAAAACCGCGATTGCGCTGCTGGCATGGTTTGTCAGTAGCGCCAGCCTGGCGGCGACGCCGTGGCAGAAAAT
AACCCATCCTGTCCCCGGCG

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MAGNTIGQLFRVTTFGESHGLALGCIVDGVPPGIPLTEADLQHDLDRRRPGTSRYTTQRREPDQVKILSGVFDGVTTGTS
IGLLIENTDQRSQDYSAIKDVFRPGHADYTYEQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGIEIRGCLTQM
GDIPLEIKDWRQVELNPFFCPDADKLDALDELMRALKKEGDSIGAKVTVMASGVPAGLGEPVFDRLDADIAHALMSINAV
KGVEIGEGFNVVALRGSQNRDEITAQGFQSNHAGGILGGISSGQHIVAHMALKPTSSITVPGRTINRMGEEVEMITKGRH
DPCVGIRAVPIAEAMLAIVLMDHLLRHRAQNADVKTEIPRW

Sequences:

>Translated_361_residues
MAGNTIGQLFRVTTFGESHGLALGCIVDGVPPGIPLTEADLQHDLDRRRPGTSRYTTQRREPDQVKILSGVFDGVTTGTS
IGLLIENTDQRSQDYSAIKDVFRPGHADYTYEQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGIEIRGCLTQM
GDIPLEIKDWRQVELNPFFCPDADKLDALDELMRALKKEGDSIGAKVTVMASGVPAGLGEPVFDRLDADIAHALMSINAV
KGVEIGEGFNVVALRGSQNRDEITAQGFQSNHAGGILGGISSGQHIVAHMALKPTSSITVPGRTINRMGEEVEMITKGRH
DPCVGIRAVPIAEAMLAIVLMDHLLRHRAQNADVKTEIPRW
>Mature_360_residues
AGNTIGQLFRVTTFGESHGLALGCIVDGVPPGIPLTEADLQHDLDRRRPGTSRYTTQRREPDQVKILSGVFDGVTTGTSI
GLLIENTDQRSQDYSAIKDVFRPGHADYTYEQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGIEIRGCLTQMG
DIPLEIKDWRQVELNPFFCPDADKLDALDELMRALKKEGDSIGAKVTVMASGVPAGLGEPVFDRLDADIAHALMSINAVK
GVEIGEGFNVVALRGSQNRDEITAQGFQSNHAGGILGGISSGQHIVAHMALKPTSSITVPGRTINRMGEEVEMITKGRHD
PCVGIRAVPIAEAMLAIVLMDHLLRHRAQNADVKTEIPRW

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=361, Percent_Identity=95.5678670360111, Blast_Score=688, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321290, Length=368, Percent_Identity=45.3804347826087, Blast_Score=310, Evalue=2e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 39169; Mature: 39038

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1 ; PS00788 CHORISMATE_SYNTHASE_2 ; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGNTIGQLFRVTTFGESHGLALGCIVDGVPPGIPLTEADLQHDLDRRRPGTSRYTTQRR
CCCCHHHHHHEEEECCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
EPDQVKILSGVFDGVTTGTSIGLLIENTDQRSQDYSAIKDVFRPGHADYTYEQKYGLRDY
CCCHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEHHHCCCHHC
RGGGRSSARETAMRVAAGAIAKKYLAEKFGIEIRGCLTQMGDIPLEIKDWRQVELNPFFC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEECCCCEEECCCEEC
PDADKLDALDELMRALKKEGDSIGAKVTVMASGVPAGLGEPVFDRLDADIAHALMSINAV
CCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGEGFNVVALRGSQNRDEITAQGFQSNHAGGILGGISSGQHIVAHMALKPTSSITV
CCCEECCCCEEEEEECCCCCCHHHHCCCCCCCCCCEEECCCCCCEEEEEEEECCCCCEEE
PGRTINRMGEEVEMITKGRHDPCVGIRAVPIAEAMLAIVLMDHLLRHRAQNADVKTEIPR
CCHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
W
C
>Mature Secondary Structure 
AGNTIGQLFRVTTFGESHGLALGCIVDGVPPGIPLTEADLQHDLDRRRPGTSRYTTQRR
CCCHHHHHHEEEECCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
EPDQVKILSGVFDGVTTGTSIGLLIENTDQRSQDYSAIKDVFRPGHADYTYEQKYGLRDY
CCCHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEHHHCCCHHC
RGGGRSSARETAMRVAAGAIAKKYLAEKFGIEIRGCLTQMGDIPLEIKDWRQVELNPFFC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEECCCCEEECCCEEC
PDADKLDALDELMRALKKEGDSIGAKVTVMASGVPAGLGEPVFDRLDADIAHALMSINAV
CCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGEGFNVVALRGSQNRDEITAQGFQSNHAGGILGGISSGQHIVAHMALKPTSSITV
CCCEECCCCEEEEEECCCCCCHHHHCCCCCCCCCCEEECCCCCCEEEEEEEECCCCCEEE
PGRTINRMGEEVEMITKGRHDPCVGIRAVPIAEAMLAIVLMDHLLRHRAQNADVKTEIPR
CCHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
W
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA