| Definition | Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633 chromosome, complete genome. |
|---|---|
| Accession | NC_011094 |
| Length | 4,709,075 |
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The map label for this gene is arnA [H]
Identifier: 194736015
GI number: 194736015
Start: 2411995
End: 2413977
Strand: Direct
Name: arnA [H]
Synonym: SeSA_A2527
Alternate gene names: 194736015
Gene position: 2411995-2413977 (Clockwise)
Preceding gene: 194735356
Following gene: 194738251
Centisome position: 51.22
GC content: 54.21
Gene sequence:
>1983_bases ATGAAAGCCGTTATTTTTGCCTATCACGATATGGGATGTCAGGGTGTGCAGGCCGTACTGGATGCCGGGTATGAGATTGC CGCGATTTTCACTCATGCCGACAATCCTGCGGAAAACACCTTTTTTGGCTCCGTCTCCCGGCTGGCGGCAGAATTAGGGA TTCCGGTTTATGCGCCGGATAACGTAAACCATCCTATCTGGGTCGACCGCATCGCTGAACTTGCGCCGGATATTATTTTT TCGTTCTATTACCGCAACCTGTTAAGCGAAGAAATTCTGCACCTCGCCCCGGCTGGCGCGTTCAATCTGCACGGTTCTCT ATTGCCTGCCTATCGTGGCCGTGCGCCGCTAAACTGGGTTCTGGTTAACGGCGAAAGCGAAACGGGCGTAACGCTGCATC GTATGGTCAAACGTGCCGACGCCGGAGAGATTGTCGCCAGTCAACGCGTTGCTATTGCGCAGGACGATGTTGCGCTTACC CTGCATCATAAGCTATGTCAGGCCGCGCGCCAGTTGCTTAATAGCATCCTGCCCACCATGAAATGCGGCGATATACCTTC TGTTCCCCAGCGAGAGTCTGACGCTACATATTATGGTCGCCGCAGGCCGGAAGATGGCCTTATCGACTGGCACAAACCGG TTTCCACGGTGCATAACCTGGTGCGGGCGGTAGCCGCCCCCTGGCCCGGCGCGTTCAGCTATAACGGCTCGCAAAAATTC ACTATCTGGTCTTCCCGAATTTGTCCGGATGCGCAGGGCGCGCTTCCCGGCTCGGTAATTTCGGTCTCTCCGCTGCGGGT CGCCTGCGCCGATGGCGCGCTGGAGATTATTACCGGCCAGGCCGGAGACGGCATTACTGTACAGGGCTCGCAGCTTGCAC AGACGCTTGGTCTGGTGGCGGGCGCGCGTTTGAACCGTCCACCAGCGACCAGCGGTAAACGTCGCATTCGCGTTCTCATC CTCGGCGTCAACGGTTTTATCGGCAATCATTTGACCGAACGGTTACTGAATGAAGAGAATTACGAGGTCTACGGTATGGA TATCGGCAGCAACGCCATTAGCCGATTCCTGCTCCACCCTCGCTTTCATTTCGTGGAGGGAGATATCAGCATCCACTCAG AATGGATCGAATACCATGTCAAAAAATGCGATGTCGTACTGCCGCTGGTAGCAATTGCTACCCCGATTGAATACACCCGC AACCCGCTGCGCGTCTTTGAACTTGATTTTGAAGAAAACCTGCGGATTATCCGTTATTGCGTGAAATACCGTAAACGCGT GGTTTTCCCGTCTACCTCTGAAGTGTACGGCATGTGTACGGACGCCTCTTTTGACGAGGATAAATCGAATCTGATCGTCG GTCCGGTGAATAAGCCACGCTGGATTTACTCCGTTTCCAAACAGCTTCTCGACCGGGTGATTTGGGCTTATGGCGAAAAA GAGGGATTGCGCTTCACGCTTTTCCGTCCCTTTAACTGGATGGGGCCGCGGCTGGATAGCCTGAACGCGGCGCGTATCGG CAGTTCACGCGCGATAACGCAGTTGATTCTGAACCTGGTAGAAGGGACGCCGATAAAGCTTATCGACGGCGGTCAGCAGA AGCGCTGCTTCACCGATATTCGTGACGGGATCGAAGCCTTATTCCGCATTATTGTGAATGATGGCGATCGGTGCGATGGC AAAATCATTAATATCGGCAACCCTGACAACGAAGCCAGTATTCAGGAACTGGCGACGCTGTTGCTCGACAGTTTTGATAA GCATCCGCTGCGCTGCCATTTCCCACCGTTTGCCGGTTTCCAGGTCGTCGAAAGCCGTAGTTATTACGGCAAGGGTTATC AGGATGTCGCACACCGGAAACCCAGTATCGACAATGCCAGGCGCTGTCTGGACTGGGAACCGTCTATTGCGATGCGGGAT ACGGTTGAAGAAACGCTGGACTTCTTTTTGCGCAGCGTAGATATCGCGGAACGCGCATCATGA
Upstream 100 bases:
>100_bases ACATCGGTCGCATTTATAACGATGTCCGCGCCCGCCCCCGCTATTTTGTTCAACAAGTTATCTACCCGGAAAGCACGCCG TTTACTGAGGAAAGTCACCA
Downstream 100 bases:
>100_bases CGAAAGTCGGTTTACGCATTGATGTTGATACCTTGCGAGGAACGCGTGAAGGTGTTCCCCGGCTGCTGGAGACATTGCAT CGCCACGGCGTTCAGGCCAG
Product: bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase
Products: NA
Alternate protein names: UDP-4-amino-4-deoxy-L-arabinose formyltransferase; ArnAFT; UDP-L-Ara4N formyltransferase; UDP-glucuronic acid oxidase, UDP-4-keto-hexauronic acid decarboxylating; ArnADH; UDP-GlcUA decarboxylase; UDP-glucuronic acid dehydrogenase [H]
Number of amino acids: Translated: 660; Mature: 660
Protein sequence:
>660_residues MKAVIFAYHDMGCQGVQAVLDAGYEIAAIFTHADNPAENTFFGSVSRLAAELGIPVYAPDNVNHPIWVDRIAELAPDIIF SFYYRNLLSEEILHLAPAGAFNLHGSLLPAYRGRAPLNWVLVNGESETGVTLHRMVKRADAGEIVASQRVAIAQDDVALT LHHKLCQAARQLLNSILPTMKCGDIPSVPQRESDATYYGRRRPEDGLIDWHKPVSTVHNLVRAVAAPWPGAFSYNGSQKF TIWSSRICPDAQGALPGSVISVSPLRVACADGALEIITGQAGDGITVQGSQLAQTLGLVAGARLNRPPATSGKRRIRVLI LGVNGFIGNHLTERLLNEENYEVYGMDIGSNAISRFLLHPRFHFVEGDISIHSEWIEYHVKKCDVVLPLVAIATPIEYTR NPLRVFELDFEENLRIIRYCVKYRKRVVFPSTSEVYGMCTDASFDEDKSNLIVGPVNKPRWIYSVSKQLLDRVIWAYGEK EGLRFTLFRPFNWMGPRLDSLNAARIGSSRAITQLILNLVEGTPIKLIDGGQQKRCFTDIRDGIEALFRIIVNDGDRCDG KIINIGNPDNEASIQELATLLLDSFDKHPLRCHFPPFAGFQVVESRSYYGKGYQDVAHRKPSIDNARRCLDWEPSIAMRD TVEETLDFFLRSVDIAERAS
Sequences:
>Translated_660_residues MKAVIFAYHDMGCQGVQAVLDAGYEIAAIFTHADNPAENTFFGSVSRLAAELGIPVYAPDNVNHPIWVDRIAELAPDIIF SFYYRNLLSEEILHLAPAGAFNLHGSLLPAYRGRAPLNWVLVNGESETGVTLHRMVKRADAGEIVASQRVAIAQDDVALT LHHKLCQAARQLLNSILPTMKCGDIPSVPQRESDATYYGRRRPEDGLIDWHKPVSTVHNLVRAVAAPWPGAFSYNGSQKF TIWSSRICPDAQGALPGSVISVSPLRVACADGALEIITGQAGDGITVQGSQLAQTLGLVAGARLNRPPATSGKRRIRVLI LGVNGFIGNHLTERLLNEENYEVYGMDIGSNAISRFLLHPRFHFVEGDISIHSEWIEYHVKKCDVVLPLVAIATPIEYTR NPLRVFELDFEENLRIIRYCVKYRKRVVFPSTSEVYGMCTDASFDEDKSNLIVGPVNKPRWIYSVSKQLLDRVIWAYGEK EGLRFTLFRPFNWMGPRLDSLNAARIGSSRAITQLILNLVEGTPIKLIDGGQQKRCFTDIRDGIEALFRIIVNDGDRCDG KIINIGNPDNEASIQELATLLLDSFDKHPLRCHFPPFAGFQVVESRSYYGKGYQDVAHRKPSIDNARRCLDWEPSIAMRD TVEETLDFFLRSVDIAERAS >Mature_660_residues MKAVIFAYHDMGCQGVQAVLDAGYEIAAIFTHADNPAENTFFGSVSRLAAELGIPVYAPDNVNHPIWVDRIAELAPDIIF SFYYRNLLSEEILHLAPAGAFNLHGSLLPAYRGRAPLNWVLVNGESETGVTLHRMVKRADAGEIVASQRVAIAQDDVALT LHHKLCQAARQLLNSILPTMKCGDIPSVPQRESDATYYGRRRPEDGLIDWHKPVSTVHNLVRAVAAPWPGAFSYNGSQKF TIWSSRICPDAQGALPGSVISVSPLRVACADGALEIITGQAGDGITVQGSQLAQTLGLVAGARLNRPPATSGKRRIRVLI LGVNGFIGNHLTERLLNEENYEVYGMDIGSNAISRFLLHPRFHFVEGDISIHSEWIEYHVKKCDVVLPLVAIATPIEYTR NPLRVFELDFEENLRIIRYCVKYRKRVVFPSTSEVYGMCTDASFDEDKSNLIVGPVNKPRWIYSVSKQLLDRVIWAYGEK EGLRFTLFRPFNWMGPRLDSLNAARIGSSRAITQLILNLVEGTPIKLIDGGQQKRCFTDIRDGIEALFRIIVNDGDRCDG KIINIGNPDNEASIQELATLLLDSFDKHPLRCHFPPFAGFQVVESRSYYGKGYQDVAHRKPSIDNARRCLDWEPSIAMRD TVEETLDFFLRSVDIAERAS
Specific function: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabin
COG id: COG0451
COG function: function code MG; Nucleoside-diphosphate-sugar epimerases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the sugar epimerase family. UDP-glucuronic acid decarboxylase subfamily [H]
Homologues:
Organism=Homo sapiens, GI42516563, Length=354, Percent_Identity=25.7062146892655, Blast_Score=114, Evalue=2e-25, Organism=Homo sapiens, GI21614513, Length=248, Percent_Identity=24.5967741935484, Blast_Score=86, Evalue=1e-16, Organism=Homo sapiens, GI238814322, Length=296, Percent_Identity=22.6351351351351, Blast_Score=70, Evalue=9e-12, Organism=Escherichia coli, GI1788589, Length=660, Percent_Identity=80, Blast_Score=1129, Evalue=0.0, Organism=Escherichia coli, GI1789683, Length=283, Percent_Identity=29.6819787985866, Blast_Score=131, Evalue=2e-31, Organism=Caenorhabditis elegans, GI17539532, Length=351, Percent_Identity=25.3561253561254, Blast_Score=117, Evalue=2e-26, Organism=Caenorhabditis elegans, GI133930964, Length=261, Percent_Identity=22.9885057471264, Blast_Score=77, Evalue=3e-14, Organism=Drosophila melanogaster, GI21356223, Length=351, Percent_Identity=25.3561253561254, Blast_Score=103, Evalue=4e-22,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR021168 - InterPro: IPR001509 - InterPro: IPR005793 - InterPro: IPR002376 - InterPro: IPR011034 - InterPro: IPR016040 [H]
Pfam domain/function: PF01370 Epimerase; PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]
EC number: =2.1.2.13; =1.1.1.305 [H]
Molecular weight: Translated: 73540; Mature: 73540
Theoretical pI: Translated: 6.79; Mature: 6.79
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.8 %Cys (Translated Protein) 1.2 %Met (Translated Protein) 3.0 %Cys+Met (Translated Protein) 1.8 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 3.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKAVIFAYHDMGCQGVQAVLDAGYEIAAIFTHADNPAENTFFGSVSRLAAELGIPVYAPD CCEEEEEEECCCHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCEECCC NVNHPIWVDRIAELAPDIIFSFYYRNLLSEEILHLAPAGAFNLHGSLLPAYRGRAPLNWV CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCEEEE LVNGESETGVTLHRMVKRADAGEIVASQRVAIAQDDVALTLHHKLCQAARQLLNSILPTM EEECCCCCCHHHHHHHHHCCCCHHHHHCCEEEECCCEEEHHHHHHHHHHHHHHHHHCCCC KCGDIPSVPQRESDATYYGRRRPEDGLIDWHKPVSTVHNLVRAVAAPWPGAFSYNGSQKF CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEE TIWSSRICPDAQGALPGSVISVSPLRVACADGALEIITGQAGDGITVQGSQLAQTLGLVA EEEECCCCCCCCCCCCCCEEEECCEEEEECCCCEEEEECCCCCCEEEEHHHHHHHHHHHH GARLNRPPATSGKRRIRVLILGVNGFIGNHLTERLLNEENYEVYGMDIGSNAISRFLLHP CCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHCC RFHFVEGDISIHSEWIEYHVKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLRIIRYC CEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEEEECHHHCHHHHHHH VKYRKRVVFPSTSEVYGMCTDASFDEDKSNLIVGPVNKPRWIYSVSKQLLDRVIWAYGEK HHHHHEECCCCCCCCEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCC EGLRFTLFRPFNWMGPRLDSLNAARIGSSRAITQLILNLVEGTPIKLIDGGQQKRCFTDI CCCEEEEECCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHH RDGIEALFRIIVNDGDRCDGKIINIGNPDNEASIQELATLLLDSFDKHPLRCHFPPFAGF HHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEECCCCCCC QVVESRSYYGKGYQDVAHRKPSIDNARRCLDWEPSIAMRDTVEETLDFFLRSVDIAERAS CEEECCCCCCCCHHHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC >Mature Secondary Structure MKAVIFAYHDMGCQGVQAVLDAGYEIAAIFTHADNPAENTFFGSVSRLAAELGIPVYAPD CCEEEEEEECCCHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCEECCC NVNHPIWVDRIAELAPDIIFSFYYRNLLSEEILHLAPAGAFNLHGSLLPAYRGRAPLNWV CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCEEEE LVNGESETGVTLHRMVKRADAGEIVASQRVAIAQDDVALTLHHKLCQAARQLLNSILPTM EEECCCCCCHHHHHHHHHCCCCHHHHHCCEEEECCCEEEHHHHHHHHHHHHHHHHHCCCC KCGDIPSVPQRESDATYYGRRRPEDGLIDWHKPVSTVHNLVRAVAAPWPGAFSYNGSQKF CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEE TIWSSRICPDAQGALPGSVISVSPLRVACADGALEIITGQAGDGITVQGSQLAQTLGLVA EEEECCCCCCCCCCCCCCEEEECCEEEEECCCCEEEEECCCCCCEEEEHHHHHHHHHHHH GARLNRPPATSGKRRIRVLILGVNGFIGNHLTERLLNEENYEVYGMDIGSNAISRFLLHP CCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHCC RFHFVEGDISIHSEWIEYHVKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLRIIRYC CEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEEEECHHHCHHHHHHH VKYRKRVVFPSTSEVYGMCTDASFDEDKSNLIVGPVNKPRWIYSVSKQLLDRVIWAYGEK HHHHHEECCCCCCCCEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCC EGLRFTLFRPFNWMGPRLDSLNAARIGSSRAITQLILNLVEGTPIKLIDGGQQKRCFTDI CCCEEEEECCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHH RDGIEALFRIIVNDGDRCDGKIINIGNPDNEASIQELATLLLDSFDKHPLRCHFPPFAGF HHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEECCCCCCC QVVESRSYYGKGYQDVAHRKPSIDNARRCLDWEPSIAMRDTVEETLDFFLRSVDIAERAS CEEECCCCCCCCHHHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA