Click here to switch to the map view.

The map label for this gene is cyaD [H]

Identifier: 194735786

GI number: 194735786

Start: 2795286

End: 2796476

Strand: Direct

Name: cyaD [H]

Synonym: SeSA_A2889

Alternate gene names: 194735786

Gene position: 2795286-2796476 (Clockwise)

Preceding gene: 194735340

Following gene: 194736662

Centisome position: 59.36

GC content: 53.65

Gene sequence:

>1191_bases
ATGAAAATCAATCAGCATGATGCCGCGATGGACGATTTCGATATTCAGCGTGAACGGGCGTTTTCCGGCGCGAGTCGTAT
TGTTCTGATCTGCTCACTGTTATTTCTCATTCTCGGCATCTGGGCGTGGTTTGGCCGGCTGGATGAGGTTTCCACCGGCA
ACGGGAAAGTGATCCCCAGTTCACGCGAACAGGTTCTGCAGTCGCTGGATGGCGGCATTCTGGCGCAGTTGACGGTGCGG
GAAGGCGACAGAGTTCAGGCTAACCAGATTGTCGCCCGGCTTGATCCGACGCGTCTGGCGTCCAATGTTGGTGAAAGTGC
GGCAAAATATCGCGCTTCACTCGCCTCCAGCGCACGGTTAACTGCGGAAGTCAGCGACTTACCTCTCGCCTTTCCCGCTG
AGCTGAACGGCTGGCCGGATCTGATTGCCGCAGAGACGCGTCTCTATAAAAGCCGCCGCGCGCAGCTGGCCGATACCGAA
GCCGAGCTACGGGATGCGCTGGCGTCGGTTAATAAAGAGCTGACCATTACCCAGCGGCTGGAGAAAAGCGGCGCGGCCAG
TCATGTTGAAGTGCTACGCCTGCAACGACAAAAAAGCGATTTAGGCTTAAAAATTACCGATCTGCGCTCACAATATTATG
TGCAGGCACGCGAAGCGTTATCGAAAGCGAACGCTGAGGTCGATATGCTCTCCGCCATTTTAAAAGGACGCGAGGATTCC
GTCACCCGCCTTACCGTGCGTTCGCCGGTACGCGGCATTGTTAAAAATATCCAGGTCACGACGATTGGCGGCGTGATCCC
GCCTAACGGCGAGATGATGGAGATAGTGCCGGTAGACGATCGTCTGCTGATTGAAACCCGCCTTTCGCCGCGTGATATCG
CCTTTATTCATCCCGGCCAACGCGCATTGGTTAAAATTACTGCTTACGATTACGCCATTTACGGCGGGCTTGACGGCGTG
GTGGAGACCATTTCACCGGACACCATTCAGGATAAAGTGAAACCGGAAATTTTCTACTATCGCGTGTTTATCCGCACCCA
CCAGGACTATCTACAAAATAAATCAGGACGCCGTTTTTCGATTGTTCCAGGCATGATCGCCACGGTGGATATCAAAACCG
GTGAAAAAACCATTGTCGACTATTTAATCAAACCGTTTAATCGCGCGAAAGAAGCGCTGCGCGAGCGGTAA

Upstream 100 bases:

>100_bases
CGTGTCATTGTCCTGAAAGAAGGACAACTGGTGATGGATGCGCCAAAAGCGCAGGCGCTTAACGCGGATCGAATGCAAAG
TCACCGTCGGGAGTGGAAAA

Downstream 100 bases:

>100_bases
ATCGTTGAAGATAAGAAGATACGGGGGCTGGTCACGCGTGTCACAAGTCTGTTATACTTACCTTACACATTGGGGCTGAT
TCTGGATTCGACGGGATTTG

Product: type I secretion membrane fusion protein, HlyD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MKINQHDAAMDDFDIQRERAFSGASRIVLICSLLFLILGIWAWFGRLDEVSTGNGKVIPSSREQVLQSLDGGILAQLTVR
EGDRVQANQIVARLDPTRLASNVGESAAKYRASLASSARLTAEVSDLPLAFPAELNGWPDLIAAETRLYKSRRAQLADTE
AELRDALASVNKELTITQRLEKSGAASHVEVLRLQRQKSDLGLKITDLRSQYYVQAREALSKANAEVDMLSAILKGREDS
VTRLTVRSPVRGIVKNIQVTTIGGVIPPNGEMMEIVPVDDRLLIETRLSPRDIAFIHPGQRALVKITAYDYAIYGGLDGV
VETISPDTIQDKVKPEIFYYRVFIRTHQDYLQNKSGRRFSIVPGMIATVDIKTGEKTIVDYLIKPFNRAKEALRER

Sequences:

>Translated_396_residues
MKINQHDAAMDDFDIQRERAFSGASRIVLICSLLFLILGIWAWFGRLDEVSTGNGKVIPSSREQVLQSLDGGILAQLTVR
EGDRVQANQIVARLDPTRLASNVGESAAKYRASLASSARLTAEVSDLPLAFPAELNGWPDLIAAETRLYKSRRAQLADTE
AELRDALASVNKELTITQRLEKSGAASHVEVLRLQRQKSDLGLKITDLRSQYYVQAREALSKANAEVDMLSAILKGREDS
VTRLTVRSPVRGIVKNIQVTTIGGVIPPNGEMMEIVPVDDRLLIETRLSPRDIAFIHPGQRALVKITAYDYAIYGGLDGV
VETISPDTIQDKVKPEIFYYRVFIRTHQDYLQNKSGRRFSIVPGMIATVDIKTGEKTIVDYLIKPFNRAKEALRER
>Mature_396_residues
MKINQHDAAMDDFDIQRERAFSGASRIVLICSLLFLILGIWAWFGRLDEVSTGNGKVIPSSREQVLQSLDGGILAQLTVR
EGDRVQANQIVARLDPTRLASNVGESAAKYRASLASSARLTAEVSDLPLAFPAELNGWPDLIAAETRLYKSRRAQLADTE
AELRDALASVNKELTITQRLEKSGAASHVEVLRLQRQKSDLGLKITDLRSQYYVQAREALSKANAEVDMLSAILKGREDS
VTRLTVRSPVRGIVKNIQVTTIGGVIPPNGEMMEIVPVDDRLLIETRLSPRDIAFIHPGQRALVKITAYDYAIYGGLDGV
VETISPDTIQDKVKPEIFYYRVFIRTHQDYLQNKSGRRFSIVPGMIATVDIKTGEKTIVDYLIKPFNRAKEALRER

Specific function: CyaD is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 44073; Mature: 44073

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS00543 HLYD_FAMILY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKINQHDAAMDDFDIQRERAFSGASRIVLICSLLFLILGIWAWFGRLDEVSTGNGKVIPS
CCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCC
SREQVLQSLDGGILAQLTVREGDRVQANQIVARLDPTRLASNVGESAAKYRASLASSARL
HHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEE
TAEVSDLPLAFPAELNGWPDLIAAETRLYKSRRAQLADTEAELRDALASVNKELTITQRL
EEECCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHH
EKSGAASHVEVLRLQRQKSDLGLKITDLRSQYYVQAREALSKANAEVDMLSAILKGREDS
HHCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCC
VTRLTVRSPVRGIVKNIQVTTIGGVIPPNGEMMEIVPVDDRLLIETRLSPRDIAFIHPGQ
EEEEEHHHHHHHHHHCCEEEEECCEECCCCCEEEEEECCCEEEEEECCCCCCEEEECCCC
RALVKITAYDYAIYGGLDGVVETISPDTIQDKVKPEIFYYRVFIRTHQDYLQNKSGRRFS
EEEEEEEEEEEEEECCHHHHHHHCCCCHHHHHCCCEEEEEEEEHHHHHHHHCCCCCCEEE
IVPGMIATVDIKTGEKTIVDYLIKPFNRAKEALRER
ECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKINQHDAAMDDFDIQRERAFSGASRIVLICSLLFLILGIWAWFGRLDEVSTGNGKVIPS
CCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCC
SREQVLQSLDGGILAQLTVREGDRVQANQIVARLDPTRLASNVGESAAKYRASLASSARL
HHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEE
TAEVSDLPLAFPAELNGWPDLIAAETRLYKSRRAQLADTEAELRDALASVNKELTITQRL
EEECCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHH
EKSGAASHVEVLRLQRQKSDLGLKITDLRSQYYVQAREALSKANAEVDMLSAILKGREDS
HHCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCC
VTRLTVRSPVRGIVKNIQVTTIGGVIPPNGEMMEIVPVDDRLLIETRLSPRDIAFIHPGQ
EEEEEHHHHHHHHHHCCEEEEECCEECCCCCEEEEEECCCEEEEEECCCCCCEEEECCCC
RALVKITAYDYAIYGGLDGVVETISPDTIQDKVKPEIFYYRVFIRTHQDYLQNKSGRRFS
EEEEEEEEEEEEEECCHHHHHHHCCCCHHHHHCCCEEEEEEEEHHHHHHHHCCCCCCEEE
IVPGMIATVDIKTGEKTIVDYLIKPFNRAKEALRER
ECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2905265; 12910271 [H]