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The map label for this gene is manX [C]

Identifier: 194735606

GI number: 194735606

Start: 4651317

End: 4651739

Strand: Direct

Name: manX [C]

Synonym: SeSA_A4789

Alternate gene names: 194735606

Gene position: 4651317-4651739 (Clockwise)

Preceding gene: 194737223

Following gene: 194735118

Centisome position: 98.77

GC content: 45.15

Gene sequence:

>423_bases
ATGAAGAGACATTATATTTTCGCCAGCCACGGCACGCTGGCCAGCGGGGTTTTAAACTCCGTGGAGCTGATTTTAGGCAA
ACGGTCAAATGTCTGGACGCTGTGCGCTTACGTTGAAGAGAGCGTGGATTTAAGCCAGCAGGTAGATATGCTAATTGCCC
GGATCCCGCCGGAAGATGAAATTATTGCGCTGACAGATATTTTTGCCGGCAGCGTGAATAATGAATTTGTCCGTTATTTA
TCACGGGAAAATTTTCATCTGCTGGCAGGGATTAACCTGCCGCTGGTTATCGATCTCTTTATGTCGGAAAACGATGGCAA
TACCACGCATACCATAATGACGGCGTTAGCGGATTCAAAAGAAAATATTCAGTACTGCAATCAAACTATCACCAGCGCCA
TGCAAAGCGATAAAGATTTTTAA

Upstream 100 bases:

>100_bases
GATTCCTCTCTGTTAACCCGCATCTTTTTTCGGCGCGCCACTTTTTCTGGCACGCCGCTTGCTCTCTTTTATCACAGTGG
AATGTGTTTTAGAGGTCAGG

Downstream 100 bases:

>100_bases
GGGGAGGAAGCGTCATGATTGTTTTTTTACGGGTGGATCATCGTTTATTACATGGACAGGTCGCCTTTTCCTGGACGCAG
TACGTTGGCGCAGACTGTAT

Product: PTS system fructose subfamily IIA component

Products: protein histidine; sugar phosphate

Alternate protein names: PTS System Fructocific IIA Component; PTS System IIA Component; PTS System N-Acetylgalactosamine-Specific IIA Component; PTS Transport System IIA Component; PTS Family Mannose/Fructose/Sorbose Porter Component IIA; PTS System Mannose/Fructose Family IIA Component; PTS System; PTS System Sorbocific IIA Component; PTS System Transporter Subunit IIA; PTS System Mannose-Specific IIA Component; PTS Permease; Phosphotransferase System

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MKRHYIFASHGTLASGVLNSVELILGKRSNVWTLCAYVEESVDLSQQVDMLIARIPPEDEIIALTDIFAGSVNNEFVRYL
SRENFHLLAGINLPLVIDLFMSENDGNTTHTIMTALADSKENIQYCNQTITSAMQSDKDF

Sequences:

>Translated_140_residues
MKRHYIFASHGTLASGVLNSVELILGKRSNVWTLCAYVEESVDLSQQVDMLIARIPPEDEIIALTDIFAGSVNNEFVRYL
SRENFHLLAGINLPLVIDLFMSENDGNTTHTIMTALADSKENIQYCNQTITSAMQSDKDF
>Mature_140_residues
MKRHYIFASHGTLASGVLNSVELILGKRSNVWTLCAYVEESVDLSQQVDMLIARIPPEDEIIALTDIFAGSVNNEFVRYL
SRENFHLLAGINLPLVIDLFMSENDGNTTHTIMTALADSKENIQYCNQTITSAMQSDKDF

Specific function: This Is A Component Of The Phosphoenolpyruvate-Dependent Sugar Phosphotransferase System (Pts), A Major Carbohydrate Active -Transport System. The IIcd Domains Contain The Sugar Binding Site And The Transmembrane Channel; The IIa Domain Contains The Prim

COG id: COG2893

COG function: function code G; Phosphotransferase system, mannose/fructose-specific component IIA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2880 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 260 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.1.69

Molecular weight: Translated: 15671; Mature: 15671

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: PS51096 PTS_EIIA_TYPE_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRHYIFASHGTLASGVLNSVELILGKRSNVWTLCAYVEESVDLSQQVDMLIARIPPEDE
CCCEEEEECCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHCCHHHHHHHHHHCCCCCCC
IIALTDIFAGSVNNEFVRYLSRENFHLLAGINLPLVIDLFMSENDGNTTHTIMTALADSK
EEEEEHHHCCCCCHHHHHHHCCCCEEEEEECCCCEEEEEEEECCCCCHHHHHHHHHHCCH
ENIQYCNQTITSAMQSDKDF
HHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKRHYIFASHGTLASGVLNSVELILGKRSNVWTLCAYVEESVDLSQQVDMLIARIPPEDE
CCCEEEEECCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHCCHHHHHHHHHHCCCCCCC
IIALTDIFAGSVNNEFVRYLSRENFHLLAGINLPLVIDLFMSENDGNTTHTIMTALADSK
EEEEEHHHCCCCCHHHHHHHCCCCEEEEEECCCCEEEEEEEECCCCCHHHHHHHHHHCCH
ENIQYCNQTITSAMQSDKDF
HHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with an alcohol group as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA