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The map label for this gene is manX [C]

Identifier: 194735118

GI number: 194735118

Start: 4651754

End: 4652215

Strand: Direct

Name: manX [C]

Synonym: SeSA_A4790

Alternate gene names: 194735118

Gene position: 4651754-4652215 (Clockwise)

Preceding gene: 194735606

Following gene: 194735621

Centisome position: 98.78

GC content: 45.45

Gene sequence:

>462_bases
ATGATTGTTTTTTTACGGGTGGATCATCGTTTATTACATGGACAGGTCGCCTTTTCCTGGACGCAGTACGTTGGCGCAGA
CTGTATTTTAATTGCCAACGACAGCGTACCTAATGATGACCTGCGTAAAACCACCATTAAAATGGCGAAGCCGCCCGCGG
TGAAGCTGGTTATTAAAAATATTGCCGATTCAATTGAAGCGATAAAAAGCGGCGTTACCGATAAATATAAACTTTTTATT
GTTGTTGAATCCGTGGCGGATGCGTACCGGCTGGCGCGCGAATTACCCGACATTAAAAGTATTAATTTAGGCGGCACGAA
GGTGCGTGAAGGGAGTCAGAATATTGCTAAAGCCATCAATCTGTTAGCGGATGAAATGACTCAACTTCGGGAGCTGGCGG
CTGGCGGAGTAGAGATAGAAATTCGGCTGGTGCCTAACGATCGTAAACAACTTTTTGCCTGA

Upstream 100 bases:

>100_bases
TGACGGCGTTAGCGGATTCAAAAGAAAATATTCAGTACTGCAATCAAACTATCACCAGCGCCATGCAAAGCGATAAAGAT
TTTTAAGGGGAGGAAGCGTC

Downstream 100 bases:

>100_bases
GCGGATACCCTCCTGAGGACATATTATGGTAGAGGCGCTTTTACTTGGACTGGTGGCGTTTATCGCCCAGTCTGAATATG
CATTAGGGACGTCGCTGATT

Product: PTS system, IIB component

Products: NA

Alternate protein names: PTS system EIIB component [H]

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MIVFLRVDHRLLHGQVAFSWTQYVGADCILIANDSVPNDDLRKTTIKMAKPPAVKLVIKNIADSIEAIKSGVTDKYKLFI
VVESVADAYRLARELPDIKSINLGGTKVREGSQNIAKAINLLADEMTQLRELAAGGVEIEIRLVPNDRKQLFA

Sequences:

>Translated_153_residues
MIVFLRVDHRLLHGQVAFSWTQYVGADCILIANDSVPNDDLRKTTIKMAKPPAVKLVIKNIADSIEAIKSGVTDKYKLFI
VVESVADAYRLARELPDIKSINLGGTKVREGSQNIAKAINLLADEMTQLRELAAGGVEIEIRLVPNDRKQLFA
>Mature_153_residues
MIVFLRVDHRLLHGQVAFSWTQYVGADCILIANDSVPNDDLRKTTIKMAKPPAVKLVIKNIADSIEAIKSGVTDKYKLFI
VVESVADAYRLARELPDIKSINLGGTKVREGSQNIAKAINLLADEMTQLRELAAGGVEIEIRLVPNDRKQLFA

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane [H]

COG id: COG3444

COG function: function code G; Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-4 domain [H]

Homologues:

Organism=Escherichia coli, GI1788120, Length=149, Percent_Identity=29.5302013422819, Blast_Score=80, Evalue=4e-17,
Organism=Escherichia coli, GI87082217, Length=146, Percent_Identity=29.4520547945205, Blast_Score=80, Evalue=4e-17,
Organism=Escherichia coli, GI1789527, Length=150, Percent_Identity=28, Blast_Score=61, Evalue=4e-11,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2880 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 260 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004720 [H]

Pfam domain/function: PF03830 PTSIIB_sorb [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 16927; Mature: 16927

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: PS51101 PTS_EIIB_TYPE_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVFLRVDHRLLHGQVAFSWTQYVGADCILIANDSVPNDDLRKTTIKMAKPPAVKLVIKN
CEEEEEECCEEHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCCCHHHHHHHH
IADSIEAIKSGVTDKYKLFIVVESVADAYRLARELPDIKSINLGGTKVREGSQNIAKAIN
HHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHCCCCCEECCCCCCCCCCHHHHHHHHH
LLADEMTQLRELAAGGVEIEIRLVPNDRKQLFA
HHHHHHHHHHHHHCCCEEEEEEECCCCHHHHCC
>Mature Secondary Structure
MIVFLRVDHRLLHGQVAFSWTQYVGADCILIANDSVPNDDLRKTTIKMAKPPAVKLVIKN
CEEEEEECCEEHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCCCHHHHHHHH
IADSIEAIKSGVTDKYKLFIVVESVADAYRLARELPDIKSINLGGTKVREGSQNIAKAIN
HHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHCCCCCEECCCCCCCCCCHHHHHHHHH
LLADEMTQLRELAAGGVEIEIRLVPNDRKQLFA
HHHHHHHHHHHHHCCCEEEEEEECCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA