Click here to switch to the map view.

The map label for this gene is add [H]

Identifier: 194735508

GI number: 194735508

Start: 1501404

End: 1502405

Strand: Reverse

Name: add [H]

Synonym: SeSA_A1561

Alternate gene names: 194735508

Gene position: 1502405-1501404 (Counterclockwise)

Preceding gene: 194733937

Following gene: 194735660

Centisome position: 31.9

GC content: 55.19

Gene sequence:

>1002_bases
ATGATTGATATTACGCTTCCTTTGACTGACATCCACCGCCACCTTGATGGCAACATTCGCGCCCAAACAATTCTGGATCT
TGGTCGGCAGTTCAACATCGCCCTTCCCGCCCAAACGCTGGAAACGTTGATTCCGCATGTCCAGGTCACCTCAACCGAAC
CCGATTTAGTGAGCTTTCTCACGAAGCTCGATTGGGGGGTAAAAGTCCTGGCATCGCTTGACGCCTGCCGCCGTGTGGCC
TTTGAAAATATTGAAGATGCCGCACGTAACGGCCTGCATTACGTCGAGCTTCGCTTTTCGCCCGGCTATATGGCGATGGC
GCATCAGTTACCGATCGCAGGCGTGGTTGAAGCCGTTATCGACGGAGTACGCGACGGCTGTAACACGTTTGGCGTCGAGG
CGCGACTCATTGGCATTATGAGCCGTACCTTCGGCGAGGCGGCATGTTTACAGGAGCTTGATGCGCTGTTGGCGCACAGA
GAGAAAATCACCGCGCTGGATTTAGCCGGTGATGAGCTGGGCTTTCCCGGCAGTCTGTTTTTGTCGCACTTTAATCGGGC
GCGCGATGCGGGCTGGCATATTACCGTTCACGCTGGCGAAGCCGCAGGGCCGGAAAGTATCTGGCAGGCGATTCGCGAAC
TGGGGGCCGAACGTATCGGACATGGCGTAAAAGCTGTCGAAGATCGCGCGTTAATGGATTTTCTTGCACAGCAGCGTATC
GGTATTGAATCCTGTCTGACCTCGAATATTCAGACCAGTACCGTCGCATCGCTGGCAGATCATCCGCTCAAAACCTTCCT
TGAGCATGGCGTTCTCGCCAGTCTTAATACGGACGATCCGGCTGTTCAGGGCGTAGATATTATCCATGAATATCACGTCG
CCGCGCCAGCGGCAGGATTGAGCCGCGAACAGATTCGCCAGGCGCAGATTAACGGTCTGGAAATCGCCTTTCTGAGCGAT
GACGAAAAACGTGCGCTGCGCGAAAAAGTGGCCGCGGCGTAA

Upstream 100 bases:

>100_bases
GCGAAGTTGCAACGTAATGGCTCCGTTTTTGCAAAATTTCCAGAGCATTATCAATCTGTAGTATAATGGTGCGCACTTTT
ATTAAAAATTGAGTGCGCCC

Downstream 100 bases:

>100_bases
GATTGCTTTATTGATGCTGACGTCCTCTCTCCGCCTGCGGTTTAATGCTATCACAGGCGGAGAAATGCGACATCTCAGGC
AAGACACAGCGTCGCGCGAT

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MIDITLPLTDIHRHLDGNIRAQTILDLGRQFNIALPAQTLETLIPHVQVTSTEPDLVSFLTKLDWGVKVLASLDACRRVA
FENIEDAARNGLHYVELRFSPGYMAMAHQLPIAGVVEAVIDGVRDGCNTFGVEARLIGIMSRTFGEAACLQELDALLAHR
EKITALDLAGDELGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAERIGHGVKAVEDRALMDFLAQQRI
GIESCLTSNIQTSTVASLADHPLKTFLEHGVLASLNTDDPAVQGVDIIHEYHVAAPAAGLSREQIRQAQINGLEIAFLSD
DEKRALREKVAAA

Sequences:

>Translated_333_residues
MIDITLPLTDIHRHLDGNIRAQTILDLGRQFNIALPAQTLETLIPHVQVTSTEPDLVSFLTKLDWGVKVLASLDACRRVA
FENIEDAARNGLHYVELRFSPGYMAMAHQLPIAGVVEAVIDGVRDGCNTFGVEARLIGIMSRTFGEAACLQELDALLAHR
EKITALDLAGDELGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAERIGHGVKAVEDRALMDFLAQQRI
GIESCLTSNIQTSTVASLADHPLKTFLEHGVLASLNTDDPAVQGVDIIHEYHVAAPAAGLSREQIRQAQINGLEIAFLSD
DEKRALREKVAAA
>Mature_333_residues
MIDITLPLTDIHRHLDGNIRAQTILDLGRQFNIALPAQTLETLIPHVQVTSTEPDLVSFLTKLDWGVKVLASLDACRRVA
FENIEDAARNGLHYVELRFSPGYMAMAHQLPIAGVVEAVIDGVRDGCNTFGVEARLIGIMSRTFGEAACLQELDALLAHR
EKITALDLAGDELGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAERIGHGVKAVEDRALMDFLAQQRI
GIESCLTSNIQTSTVASLADHPLKTFLEHGVLASLNTDDPAVQGVDIIHEYHVAAPAAGLSREQIRQAQINGLEIAFLSD
DEKRALREKVAAA

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=339, Percent_Identity=33.9233038348083, Blast_Score=165, Evalue=7e-41,
Organism=Escherichia coli, GI1787910, Length=332, Percent_Identity=90.0602409638554, Blast_Score=620, Evalue=1e-179,
Organism=Caenorhabditis elegans, GI32565969, Length=344, Percent_Identity=32.2674418604651, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17538512, Length=344, Percent_Identity=32.2674418604651, Blast_Score=135, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6324188, Length=335, Percent_Identity=26.2686567164179, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24645260, Length=334, Percent_Identity=25.748502994012, Blast_Score=107, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006650
- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 36221; Mature: 36221

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00485 A_DEAMINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDITLPLTDIHRHLDGNIRAQTILDLGRQFNIALPAQTLETLIPHVQVTSTEPDLVSFL
CEEEEECHHHHHHHCCCCCHHHHHHHCCCCCEEECCHHHHHHHCCCEEEECCCHHHHHHH
TKLDWGVKVLASLDACRRVAFENIEDAARNGLHYVELRFSPGYMAMAHQLPIAGVVEAVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHCCHHHHHHHHH
DGVRDGCNTFGVEARLIGIMSRTFGEAACLQELDALLAHREKITALDLAGDELGFPGSLF
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCHHHH
LSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAERIGHGVKAVEDRALMDFLAQQRI
HHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
GIESCLTSNIQTSTVASLADHPLKTFLEHGVLASLNTDDPAVQGVDIIHEYHVAAPAAGL
CHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCC
SREQIRQAQINGLEIAFLSDDEKRALREKVAAA
CHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCC
>Mature Secondary Structure
MIDITLPLTDIHRHLDGNIRAQTILDLGRQFNIALPAQTLETLIPHVQVTSTEPDLVSFL
CEEEEECHHHHHHHCCCCCHHHHHHHCCCCCEEECCHHHHHHHCCCEEEECCCHHHHHHH
TKLDWGVKVLASLDACRRVAFENIEDAARNGLHYVELRFSPGYMAMAHQLPIAGVVEAVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHCCHHHHHHHHH
DGVRDGCNTFGVEARLIGIMSRTFGEAACLQELDALLAHREKITALDLAGDELGFPGSLF
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCHHHH
LSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAERIGHGVKAVEDRALMDFLAQQRI
HHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
GIESCLTSNIQTSTVASLADHPLKTFLEHGVLASLNTDDPAVQGVDIIHEYHVAAPAAGL
CHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCC
SREQIRQAQINGLEIAFLSDDEKRALREKVAAA
CHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA