Click here to switch to the map view.

The map label for this gene is sipD [H]

Identifier: 194735353

GI number: 194735353

Start: 2933960

End: 2934982

Strand: Reverse

Name: sipD [H]

Synonym: SeSA_A3036

Alternate gene names: 194735353

Gene position: 2934982-2933960 (Counterclockwise)

Preceding gene: 194735025

Following gene: 194735289

Centisome position: 62.33

GC content: 47.02

Gene sequence:

>1023_bases
ATGCTTAATATTCAAAATTATTCCGCTTCTCCTCATCCGGGGATCGTTGCCGAACGGCCGCAGACTCCCTCGGCGAGCGA
GCACGTCGAGACTGCCGTGGTACCGTCTACCACAGAACATCGCGGCACAGATATCATTTCATTATCGCAGGCGGCTACTA
AAATCCAGCAGGCACAGCAGACGCTGCAGTCAACGCCACCGATCTCTGAAGAGAATAATGACGAGCGCACGCTGGCGCGC
CAACAGTTGACCAGCAGCCTGAATGCTCTGGCGAAGTCTGGCGTGTCATTATCCGCAGAACAAAATGAGAACCTGCGGAG
CGCGTTTTCTGCGCCGACGTCGGCCTTATTTAGCGCTTCGCCTATGGCGCAACCGAGAACAACCATTTCTGATGCTGAGA
TTTGGGATATGGTTTCCCAAAATATATCGGCGATAGGTGACAGCTATCTGGGCGTTTATGAAAACGTTGTCGCAGTCTAT
ACCGATTTTTATCAGGCCTTCAGTGATATTCTTTCCAAAATGGGAGGCTGGTTATCGCCTGGTAAGGATGGAAATACCAT
TAAGCTAAATGTTGACTCACTTAAAAGTGAAATAAGTAGTTTAATTAATAAATACACTCAAATAAATAAAAATACGATTT
TATTTCCCTCGCAAACTGGCAGCGGAGTGACAACAGCAACGAAAGCGGAAGCTGAGCAGTGGATTAAAGAATTGAATTTA
CCGGACAGCTGTCTAAAGGCGTCTGGTTCTGGTTATGTCGTACTGGTGGATACGGGGCCACTGAGCAAAATGGTTAGCGA
TCTTAATGGAATAGGATCGGGTTCAGCCCTTGAACTGGATAACGCCAAATATCAAGCCTGGCAGTCGGGTTTTAAAGCAC
AGGAAGAAAATCTGAAAACCACATTACAGACGCTGACGCAAAAATACAGCAATGCCAATTCATTGTACGACAACCTGGTA
AAAGTGCTGAGCAGTACGATAAGTAGCAGCCTGGAAACCGCCAAAAGCTTCCTGCAAGGATAA

Upstream 100 bases:

>100_bases
GCTGCTATCGCAGGCAATATTCGCGCTTAATCTGAAAGGTCATCTATACGCCATCATGGGTGTGATTTAATCGCGCTCCT
GATGGCGAACTGGGGATATT

Downstream 100 bases:

>100_bases
CAGAAGAGGATATTAATAATGGTTACAAGTGTAAGAACTCAGCCCCCCGTCATAATGCCAGGTATGCAGACCGAGATCAA
AACGCAGGCCACGAATCTTG

Product: type III effector protein IpaD/SipD/SspD

Products: NA

Alternate protein names: Salmonella invasion protein D [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MLNIQNYSASPHPGIVAERPQTPSASEHVETAVVPSTTEHRGTDIISLSQAATKIQQAQQTLQSTPPISEENNDERTLAR
QQLTSSLNALAKSGVSLSAEQNENLRSAFSAPTSALFSASPMAQPRTTISDAEIWDMVSQNISAIGDSYLGVYENVVAVY
TDFYQAFSDILSKMGGWLSPGKDGNTIKLNVDSLKSEISSLINKYTQINKNTILFPSQTGSGVTTATKAEAEQWIKELNL
PDSCLKASGSGYVVLVDTGPLSKMVSDLNGIGSGSALELDNAKYQAWQSGFKAQEENLKTTLQTLTQKYSNANSLYDNLV
KVLSSTISSSLETAKSFLQG

Sequences:

>Translated_340_residues
MLNIQNYSASPHPGIVAERPQTPSASEHVETAVVPSTTEHRGTDIISLSQAATKIQQAQQTLQSTPPISEENNDERTLAR
QQLTSSLNALAKSGVSLSAEQNENLRSAFSAPTSALFSASPMAQPRTTISDAEIWDMVSQNISAIGDSYLGVYENVVAVY
TDFYQAFSDILSKMGGWLSPGKDGNTIKLNVDSLKSEISSLINKYTQINKNTILFPSQTGSGVTTATKAEAEQWIKELNL
PDSCLKASGSGYVVLVDTGPLSKMVSDLNGIGSGSALELDNAKYQAWQSGFKAQEENLKTTLQTLTQKYSNANSLYDNLV
KVLSSTISSSLETAKSFLQG
>Mature_340_residues
MLNIQNYSASPHPGIVAERPQTPSASEHVETAVVPSTTEHRGTDIISLSQAATKIQQAQQTLQSTPPISEENNDERTLAR
QQLTSSLNALAKSGVSLSAEQNENLRSAFSAPTSALFSASPMAQPRTTISDAEIWDMVSQNISAIGDSYLGVYENVVAVY
TDFYQAFSDILSKMGGWLSPGKDGNTIKLNVDSLKSEISSLINKYTQINKNTILFPSQTGSGVTTATKAEAEQWIKELNL
PDSCLKASGSGYVVLVDTGPLSKMVSDLNGIGSGSALELDNAKYQAWQSGFKAQEENLKTTLQTLTQKYSNANSLYDNLV
KVLSSTISSSLETAKSFLQG

Specific function: Required for translocation of effector proteins via the type III secretion system SPI-1, which is essential for an efficient bacterial internalization. Probably acts by modulating the secretion of sipA, sipB, and sipC [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Note=Secreted via the type III secretion system 1 (SPI-1 TTSS). Localizes to the tip of the external secretion needle that is part of the TTSS apparatus (By similarity) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the invasin protein D family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009483
- InterPro:   IPR013386 [H]

Pfam domain/function: PF06511 IpaD [H]

EC number: NA

Molecular weight: Translated: 36503; Mature: 36503

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNIQNYSASPHPGIVAERPQTPSASEHVETAVVPSTTEHRGTDIISLSQAATKIQQAQQ
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
TLQSTPPISEENNDERTLARQQLTSSLNALAKSGVSLSAEQNENLRSAFSAPTSALFSAS
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCHHHHHCCC
PMAQPRTTISDAEIWDMVSQNISAIGDSYLGVYENVVAVYTDFYQAFSDILSKMGGWLSP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GKDGNTIKLNVDSLKSEISSLINKYTQINKNTILFPSQTGSGVTTATKAEAEQWIKELNL
CCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCC
PDSCLKASGSGYVVLVDTGPLSKMVSDLNGIGSGSALELDNAKYQAWQSGFKAQEENLKT
CHHHHHCCCCCEEEEEECCCHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHH
TLQTLTQKYSNANSLYDNLVKVLSSTISSSLETAKSFLQG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLNIQNYSASPHPGIVAERPQTPSASEHVETAVVPSTTEHRGTDIISLSQAATKIQQAQQ
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
TLQSTPPISEENNDERTLARQQLTSSLNALAKSGVSLSAEQNENLRSAFSAPTSALFSAS
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCHHHHHCCC
PMAQPRTTISDAEIWDMVSQNISAIGDSYLGVYENVVAVYTDFYQAFSDILSKMGGWLSP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GKDGNTIKLNVDSLKSEISSLINKYTQINKNTILFPSQTGSGVTTATKAEAEQWIKELNL
CCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCC
PDSCLKASGSGYVVLVDTGPLSKMVSDLNGIGSGSALELDNAKYQAWQSGFKAQEENLKT
CHHHHHCCCCCEEEEEECCCHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHH
TLQTLTQKYSNANSLYDNLVKVLSSTISSSLETAKSFLQG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA