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The map label for this gene is dacC [H]

Identifier: 194735164

GI number: 194735164

Start: 988549

End: 989829

Strand: Direct

Name: dacC [H]

Synonym: SeSA_A1015

Alternate gene names: 194735164

Gene position: 988549-989829 (Clockwise)

Preceding gene: 194735646

Following gene: 194734294

Centisome position: 20.99

GC content: 53.47

Gene sequence:

>1281_bases
GTGAGTGCGTTATTACTCACCGCACTTATTACACGGTGGTGTGACGTGTGTTTTTGGAATGGATACTCGGGTGGTACTAT
GACGCAATACGCTTCTTCCCTTCGTAGCCTCGCGGCAGGTTCGGTTCTCTTATTCCTTTTCGCTTCGCCTGTAAAGGCAG
AGGAACAAACGATCGCGCCGCCGGGCGTTGATGCGCGAGCCTGGATCTTAATGGATTACGCCAGCGGTAAAGTACTGGCG
GAAGGCAACGCCGATGAGAAACTCGACCCTGCCAGTTTGACAAAAATTATGACCAGCTACGTGGTGGGCCAGGCGCTGAA
GGCAGGGAAAATCAAGCTGACCGATATGGTGACGGTGGGCAAAGATGCCTGGGCGACGGGGAACCCGGCGCTACGTGGGT
CGTCGGTGATGTTTCTGAAGCCAGGCGATCAGGTGTCGGTTGCGGATCTTAATAAAGGCATCATCATTCAGTCAGGTAAT
GATGCCTGTATCGCGCTTGCCGACTACGTCGCCGGAAGCCAGGAGTCCTTTATCGGCCTGATGAACGCCTATGCGAAACG
ACTGGGGTTAACGAATACAACCTTCCAGACGGTACACGGTCTTGATGCGCCAGGGCAGTTCAGTACCGCTCGCGATATGG
CGTTGCTCGGCAAGGCCTTGATTCACGATGTGCCTGACGAATACGCCATTCATAAAGAGAAAGAATTTACTTTTAATAAT
ATTCGTCAACCGAACCGCAACCGCCTGTTGTGGAGCACCAATCTGCATGTCGACGGCATGAAAACGGGGACAACGGCAGG
GGCTGGGTATAACCTTGTCGCCTCCGCCACCCAGGGCGATATGCGCCTGATCTCTGTCGTGCTGGGGGCGAAAACGGACC
GTATTCGTTTTAATGAGTCAGAAAAACTGTTGACCTGGGGTTTCCGCTTCTTTGAAACGGTCACGCCGATTAAACCTGAC
GCGACATTCGTGACGCAACGGGTCTGGTTTGGCGATAAGCGTGAGGTCAATTTGGGGGCGGGCGATGCGGGGTCTGTGAC
GATTCCGCGTGGGCAGCTTAAAAACCTGAAGGCCAGCTTTACGTTGAACGAACCACAGCTCACGGCGCCGTTGAAGAAAG
GGCAGGTTGTCGGCACCATCGATTTCCAGCTTAACGGAAAATCCATTGAGCAACGCCCGTTAATGGTGATGGAAAACGTC
GAGGAGGGGGGATTTTTCAGCCGGATGTGGGATTTTGTGCTGATGAAACTCCATCAGTGGTTTGGCAGTTGGTTCTCGTA
A

Upstream 100 bases:

>100_bases
TTACACAATGGTCTGTAAAAAAATCGTTATGAAGGAAGCGTAACGGGATGTTATTGCATAAACTTTAAAAACTTTACCAA
GTTACGGTTTCTTTAACGTC

Downstream 100 bases:

>100_bases
AATAACCCCGTTGCCGGGTGCGCGTCGCATCCGGCAACGGGCGGTTAATACATCAGAGTAATTTGTTGCGCTTTAGCGTA
GGCCACAAAGGCCTCATCGG

Product: D-alanyl-D-alanine carboxypeptidase fraction C

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MSALLLTALITRWCDVCFWNGYSGGTMTQYASSLRSLAAGSVLLFLFASPVKAEEQTIAPPGVDARAWILMDYASGKVLA
EGNADEKLDPASLTKIMTSYVVGQALKAGKIKLTDMVTVGKDAWATGNPALRGSSVMFLKPGDQVSVADLNKGIIIQSGN
DACIALADYVAGSQESFIGLMNAYAKRLGLTNTTFQTVHGLDAPGQFSTARDMALLGKALIHDVPDEYAIHKEKEFTFNN
IRQPNRNRLLWSTNLHVDGMKTGTTAGAGYNLVASATQGDMRLISVVLGAKTDRIRFNESEKLLTWGFRFFETVTPIKPD
ATFVTQRVWFGDKREVNLGAGDAGSVTIPRGQLKNLKASFTLNEPQLTAPLKKGQVVGTIDFQLNGKSIEQRPLMVMENV
EEGGFFSRMWDFVLMKLHQWFGSWFS

Sequences:

>Translated_426_residues
MSALLLTALITRWCDVCFWNGYSGGTMTQYASSLRSLAAGSVLLFLFASPVKAEEQTIAPPGVDARAWILMDYASGKVLA
EGNADEKLDPASLTKIMTSYVVGQALKAGKIKLTDMVTVGKDAWATGNPALRGSSVMFLKPGDQVSVADLNKGIIIQSGN
DACIALADYVAGSQESFIGLMNAYAKRLGLTNTTFQTVHGLDAPGQFSTARDMALLGKALIHDVPDEYAIHKEKEFTFNN
IRQPNRNRLLWSTNLHVDGMKTGTTAGAGYNLVASATQGDMRLISVVLGAKTDRIRFNESEKLLTWGFRFFETVTPIKPD
ATFVTQRVWFGDKREVNLGAGDAGSVTIPRGQLKNLKASFTLNEPQLTAPLKKGQVVGTIDFQLNGKSIEQRPLMVMENV
EEGGFFSRMWDFVLMKLHQWFGSWFS
>Mature_425_residues
SALLLTALITRWCDVCFWNGYSGGTMTQYASSLRSLAAGSVLLFLFASPVKAEEQTIAPPGVDARAWILMDYASGKVLAE
GNADEKLDPASLTKIMTSYVVGQALKAGKIKLTDMVTVGKDAWATGNPALRGSSVMFLKPGDQVSVADLNKGIIIQSGND
ACIALADYVAGSQESFIGLMNAYAKRLGLTNTTFQTVHGLDAPGQFSTARDMALLGKALIHDVPDEYAIHKEKEFTFNNI
RQPNRNRLLWSTNLHVDGMKTGTTAGAGYNLVASATQGDMRLISVVLGAKTDRIRFNESEKLLTWGFRFFETVTPIKPDA
TFVTQRVWFGDKREVNLGAGDAGSVTIPRGQLKNLKASFTLNEPQLTAPLKKGQVVGTIDFQLNGKSIEQRPLMVMENVE
EGGFFSRMWDFVLMKLHQWFGSWFS

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=400, Percent_Identity=92.25, Blast_Score=763, Evalue=0.0,
Organism=Escherichia coli, GI1786851, Length=397, Percent_Identity=60.7052896725441, Blast_Score=500, Evalue=1e-143,
Organism=Escherichia coli, GI87082022, Length=384, Percent_Identity=46.875, Blast_Score=373, Evalue=1e-104,
Organism=Escherichia coli, GI87082054, Length=251, Percent_Identity=27.4900398406374, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 46545; Mature: 46414

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALLLTALITRWCDVCFWNGYSGGTMTQYASSLRSLAAGSVLLFLFASPVKAEEQTIAP
CHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCC
PGVDARAWILMDYASGKVLAEGNADEKLDPASLTKIMTSYVVGQALKAGKIKLTDMVTVG
CCCCCEEEEEEEECCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEC
KDAWATGNPALRGSSVMFLKPGDQVSVADLNKGIIIQSGNDACIALADYVAGSQESFIGL
CCCCCCCCCCCCCCEEEEECCCCEEEEEECCCCEEEECCCCCEEEEEHHHCCCHHHHHHH
MNAYAKRLGLTNTTFQTVHGLDAPGQFSTARDMALLGKALIHDVPDEYAIHKEKEFTFNN
HHHHHHHHCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHH
IRQPNRNRLLWSTNLHVDGMKTGTTAGAGYNLVASATQGDMRLISVVLGAKTDRIRFNES
CCCCCCCEEEEEECEEECCCCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCEEECCC
EKLLTWGFRFFETVTPIKPDATFVTQRVWFGDKREVNLGAGDAGSVTIPRGQLKNLKASF
CCEEHHHHHHHHHCCCCCCCHHHHEEEEECCCCEEEEECCCCCCCEEECCHHHCCCEEEE
TLNEPQLTAPLKKGQVVGTIDFQLNGKSIEQRPLMVMENVEEGGFFSRMWDFVLMKLHQW
EECCCCEECCCCCCCEEEEEEEEECCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHH
FGSWFS
HHHHCC
>Mature Secondary Structure 
SALLLTALITRWCDVCFWNGYSGGTMTQYASSLRSLAAGSVLLFLFASPVKAEEQTIAP
HHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCC
PGVDARAWILMDYASGKVLAEGNADEKLDPASLTKIMTSYVVGQALKAGKIKLTDMVTVG
CCCCCEEEEEEEECCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEC
KDAWATGNPALRGSSVMFLKPGDQVSVADLNKGIIIQSGNDACIALADYVAGSQESFIGL
CCCCCCCCCCCCCCEEEEECCCCEEEEEECCCCEEEECCCCCEEEEEHHHCCCHHHHHHH
MNAYAKRLGLTNTTFQTVHGLDAPGQFSTARDMALLGKALIHDVPDEYAIHKEKEFTFNN
HHHHHHHHCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHH
IRQPNRNRLLWSTNLHVDGMKTGTTAGAGYNLVASATQGDMRLISVVLGAKTDRIRFNES
CCCCCCCEEEEEECEEECCCCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCEEECCC
EKLLTWGFRFFETVTPIKPDATFVTQRVWFGDKREVNLGAGDAGSVTIPRGQLKNLKASF
CCEEHHHHHHHHHCCCCCCCHHHHEEEEECCCCEEEEECCCCCCCEEECCHHHCCCEEEE
TLNEPQLTAPLKKGQVVGTIDFQLNGKSIEQRPLMVMENVEEGGFFSRMWDFVLMKLHQW
EECCCCEECCCCCCCEEEEEEEEECCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHH
FGSWFS
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]