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The map label for this gene is lldR [H]

Identifier: 194735151

GI number: 194735151

Start: 3766990

End: 3767766

Strand: Direct

Name: lldR [H]

Synonym: SeSA_A3894

Alternate gene names: 194735151

Gene position: 3766990-3767766 (Clockwise)

Preceding gene: 194737852

Following gene: 194734323

Centisome position: 79.99

GC content: 57.79

Gene sequence:

>777_bases
GTGATTGTGATGCCAAAACGCCTGTCTGACGAGATTGCCTCTCGCGTGCGGGCGCTGATTGAAGAACAAAACCTGGAAGC
GGGCATGAAATTGCCCGCCGAGCGCCAGTTGGCTCTACAGCTTGGCGTATCACGCAACTCTTTACGCGAAGCGCTGGCGA
AGCTGGTCAGTGAAGGCGTGCTGGTGAGTCGTCGCGGCGGCGGGACATTTGTCCGCTGGCAACACGAAACCTGGTCTGAA
CAGAATATCGTTCAGCCGCTGAAAACCCTGCTGGCGGACGATCCTGATTACAGCTTCGACATTCTGGAAGCCCGCCACGC
CATTGAAGCCAGTACGGCCTGGCACGCCGCCATGCGGGCCACCAGCGCCGACAAAGAGAAGATCAGACTCTGCTTTGATG
CGACGCTCAGCGAAGACCCGGATCTCGCCTCCCAAGCCGACGTGCGCTTTCATCTGGCGATCGCGGAAGCCTCGCACAAT
GTGGTGCTGTTGCAAACCATGCGCGGTTTCTTCGACGTCCTGCAATCCTCCGTCAAACAGAGTCGCCAGCGTATGTATCT
CGTTCCGCCCGTATTCTCAAAGCTGACGGAACAACACCAGGCGGTGATGGACGCCATTCTGGACGGTAACGCCGACGGCG
CGCGTAAAGCGATGATGGCGCACCTCAGTTTTGTCCACACCACGATTAAACGATTTGATGAAGACCAGGCCCGCCAGGCG
CGTATTACCCGCCTGCCCGGCGACCATAATGAGATGACCAGGGAGAATAAATCATGA

Upstream 100 bases:

>100_bases
CCGATCTGTTCCGTTTTACCGTCAAACACAGCCTGATCTTCACCTGTATGGTGGGCGTGATCACTACGCTTCAGGCCTAT
GTTTTAACCTGGATGATTCC

Downstream 100 bases:

>100_bases
TTATTTCAGCAGCCAGCGATTATCGCGCCGCAGCTCAGCGCACGTTGCCTCCTTTCCTCTTCCACTACATCGACGGCGGC
GCGTATGCGGAATATACCCT

Product: DNA-binding transcriptional repressor LldR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MIVMPKRLSDEIASRVRALIEEQNLEAGMKLPAERQLALQLGVSRNSLREALAKLVSEGVLVSRRGGGTFVRWQHETWSE
QNIVQPLKTLLADDPDYSFDILEARHAIEASTAWHAAMRATSADKEKIRLCFDATLSEDPDLASQADVRFHLAIAEASHN
VVLLQTMRGFFDVLQSSVKQSRQRMYLVPPVFSKLTEQHQAVMDAILDGNADGARKAMMAHLSFVHTTIKRFDEDQARQA
RITRLPGDHNEMTRENKS

Sequences:

>Translated_258_residues
MIVMPKRLSDEIASRVRALIEEQNLEAGMKLPAERQLALQLGVSRNSLREALAKLVSEGVLVSRRGGGTFVRWQHETWSE
QNIVQPLKTLLADDPDYSFDILEARHAIEASTAWHAAMRATSADKEKIRLCFDATLSEDPDLASQADVRFHLAIAEASHN
VVLLQTMRGFFDVLQSSVKQSRQRMYLVPPVFSKLTEQHQAVMDAILDGNADGARKAMMAHLSFVHTTIKRFDEDQARQA
RITRLPGDHNEMTRENKS
>Mature_258_residues
MIVMPKRLSDEIASRVRALIEEQNLEAGMKLPAERQLALQLGVSRNSLREALAKLVSEGVLVSRRGGGTFVRWQHETWSE
QNIVQPLKTLLADDPDYSFDILEARHAIEASTAWHAAMRATSADKEKIRLCFDATLSEDPDLASQADVRFHLAIAEASHN
VVLLQTMRGFFDVLQSSVKQSRQRMYLVPPVFSKLTEQHQAVMDAILDGNADGARKAMMAHLSFVHTTIKRFDEDQARQA
RITRLPGDHNEMTRENKS

Specific function: May be a regulatory protein for the LCT genes [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790032, Length=258, Percent_Identity=87.2093023255814, Blast_Score=477, Evalue=1e-136,
Organism=Escherichia coli, GI1786303, Length=232, Percent_Identity=40.0862068965517, Blast_Score=154, Evalue=7e-39,
Organism=Escherichia coli, GI1789353, Length=228, Percent_Identity=32.0175438596491, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1790780, Length=235, Percent_Identity=31.063829787234, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI87082208, Length=238, Percent_Identity=27.3109243697479, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI48994955, Length=212, Percent_Identity=27.8301886792453, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 29058; Mature: 29058

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVMPKRLSDEIASRVRALIEEQNLEAGMKLPAERQLALQLGVSRNSLREALAKLVSEGV
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCE
LVSRRGGGTFVRWQHETWSEQNIVQPLKTLLADDPDYSFDILEARHAIEASTAWHAAMRA
EEEECCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TSADKEKIRLCFDATLSEDPDLASQADVRFHLAIAEASHNVVLLQTMRGFFDVLQSSVKQ
CCCCHHHHHHHEECCCCCCCCCCCCCCEEEEEEEEECCCCEEHHHHHHHHHHHHHHHHHH
SRQRMYLVPPVFSKLTEQHQAVMDAILDGNADGARKAMMAHLSFVHTTIKRFDEDQARQA
HHHCEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHH
RITRLPGDHNEMTRENKS
HHHCCCCCCHHHCCCCCC
>Mature Secondary Structure
MIVMPKRLSDEIASRVRALIEEQNLEAGMKLPAERQLALQLGVSRNSLREALAKLVSEGV
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCE
LVSRRGGGTFVRWQHETWSEQNIVQPLKTLLADDPDYSFDILEARHAIEASTAWHAAMRA
EEEECCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TSADKEKIRLCFDATLSEDPDLASQADVRFHLAIAEASHNVVLLQTMRGFFDVLQSSVKQ
CCCCHHHHHHHEECCCCCCCCCCCCCCEEEEEEEEECCCCEEHHHHHHHHHHHHHHHHHH
SRQRMYLVPPVFSKLTEQHQAVMDAILDGNADGARKAMMAHLSFVHTTIKRFDEDQARQA
HHHCEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHH
RITRLPGDHNEMTRENKS
HHHCCCCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8407843; 8041620; 9278503 [H]