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The map label for this gene is nanR [H]

Identifier: 194734653

GI number: 194734653

Start: 3408279

End: 3409007

Strand: Reverse

Name: nanR [H]

Synonym: SeSA_A3533

Alternate gene names: 194734653

Gene position: 3409007-3408279 (Counterclockwise)

Preceding gene: 194734168

Following gene: 194737314

Centisome position: 72.39

GC content: 52.4

Gene sequence:

>729_bases
TTGCGCCGCCGTCCGCTGGCGCGTAAAAAACTGTCTGAAATGGTTGAGGAAGAGCTGGAGCAGATGATCCGCCGTCATGA
GTTTGGCGAGGGAGAACAGCTACCGTCTGAACGTGAATTAATGGCCTTCTTCAATGTGGGACGTCCCTCTGTGCGTGAAG
CGTTAGCTGCGCTGAAGCGTAAAGGCTTGGTGCAAATCAATAACGGCGAACGCGCCCGCGTCTCGCGCCCCTCTGCTGAT
ACCATCATCAGCGAACTGTCGGGTATGGCGAAAGATTTTCTTACTCATCCTGGCGGCATCGCTCACTTTGAACAGCTACG
GCTTTTCTTTGAATCCAGCCTGGTACGCTATGCGGCGGAACATGCCACCGACGAGCAGATCGCGTTGTTAACGAAAGCAC
TGGAAATTAATAGCCAGTCGCTGGATGACAACGCGCTGTTTATTCGTTCGGATGTCGAGTTTCACCGGGTGCTGGCTGAA
ATTCCCGGCAATCCGATCTTTATGGCTATTCATGTTGCTCTGCTGGACTGGCTAATCGCCGCTCGCCCAAGCGTTCCCGA
TCGTGAGCTGCATGAACATAATAACTTGAGTTATCAACAGCATATTGTGATTGTTGATGCCATTCGCCAGCGAGATCCCG
ATAAAGCGGATCGCGCTCTGCAAACCCACCTCAATAGCGTTTCCGCTACCTGGCACGCGCTCGGTAAAAAAAGTCAAAAA
ATGCGGTAG

Upstream 100 bases:

>100_bases
GATAAGCTTGCTATTATTTGCCACCGACCACTCATGAATGGACGTTATGAACGCATTTGATTCGCAAGCAGAAGATTCAC
CGACATCCCTCGGGCGTAGT

Downstream 100 bases:

>100_bases
CGATCGCACCTCCGATCCCGGTTTAGTGAAGCAGATCGCACTATAAGCGTTCTGTATTATTTGCTGCTTATTTGATCTGG
TATAACAGGTATAAAGGTAG

Product: transcriptional regulator NanR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MRRRPLARKKLSEMVEEELEQMIRRHEFGEGEQLPSERELMAFFNVGRPSVREALAALKRKGLVQINNGERARVSRPSAD
TIISELSGMAKDFLTHPGGIAHFEQLRLFFESSLVRYAAEHATDEQIALLTKALEINSQSLDDNALFIRSDVEFHRVLAE
IPGNPIFMAIHVALLDWLIAARPSVPDRELHEHNNLSYQQHIVIVDAIRQRDPDKADRALQTHLNSVSATWHALGKKSQK
MR

Sequences:

>Translated_242_residues
MRRRPLARKKLSEMVEEELEQMIRRHEFGEGEQLPSERELMAFFNVGRPSVREALAALKRKGLVQINNGERARVSRPSAD
TIISELSGMAKDFLTHPGGIAHFEQLRLFFESSLVRYAAEHATDEQIALLTKALEINSQSLDDNALFIRSDVEFHRVLAE
IPGNPIFMAIHVALLDWLIAARPSVPDRELHEHNNLSYQQHIVIVDAIRQRDPDKADRALQTHLNSVSATWHALGKKSQK
MR
>Mature_242_residues
MRRRPLARKKLSEMVEEELEQMIRRHEFGEGEQLPSERELMAFFNVGRPSVREALAALKRKGLVQINNGERARVSRPSAD
TIISELSGMAKDFLTHPGGIAHFEQLRLFFESSLVRYAAEHATDEQIALLTKALEINSQSLDDNALFIRSDVEFHRVLAE
IPGNPIFMAIHVALLDWLIAARPSVPDRELHEHNNLSYQQHIVIVDAIRQRDPDKADRALQTHLNSVSATWHALGKKSQK
MR

Specific function: Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789621, Length=242, Percent_Identity=88.8429752066116, Blast_Score=444, Evalue=1e-126,
Organism=Escherichia coli, GI1789353, Length=232, Percent_Identity=24.1379310344828, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1790780, Length=224, Percent_Identity=29.0178571428571, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 27595; Mature: 27595

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRRPLARKKLSEMVEEELEQMIRRHEFGEGEQLPSERELMAFFNVGRPSVREALAALKR
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHH
KGLVQINNGERARVSRPSADTIISELSGMAKDFLTHPGGIAHFEQLRLFFESSLVRYAAE
CCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
HATDEQIALLTKALEINSQSLDDNALFIRSDVEFHRVLAEIPGNPIFMAIHVALLDWLIA
HCCHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ARPSVPDRELHEHNNLSYQQHIVIVDAIRQRDPDKADRALQTHLNSVSATWHALGKKSQK
CCCCCCCHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHC
MR
CC
>Mature Secondary Structure
MRRRPLARKKLSEMVEEELEQMIRRHEFGEGEQLPSERELMAFFNVGRPSVREALAALKR
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHH
KGLVQINNGERARVSRPSADTIISELSGMAKDFLTHPGGIAHFEQLRLFFESSLVRYAAE
CCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
HATDEQIALLTKALEINSQSLDDNALFIRSDVEFHRVLAEIPGNPIFMAIHVALLDWLIA
HCCHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ARPSVPDRELHEHNNLSYQQHIVIVDAIRQRDPDKADRALQTHLNSVSATWHALGKKSQK
CCCCCCCHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHC
MR
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA