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The map label for this gene is fixC [H]

Identifier: 194734230

GI number: 194734230

Start: 90455

End: 91741

Strand: Direct

Name: fixC [H]

Synonym: SeSA_A0087

Alternate gene names: 194734230

Gene position: 90455-91741 (Clockwise)

Preceding gene: 194738218

Following gene: 194734964

Centisome position: 1.92

GC content: 55.94

Gene sequence:

>1287_bases
ATGTCCGAAGATATCTTTGATGCCATCATCGTGGGTGCAGGTCTGGCCGGTTCGGTTGCGGCGCTGGTGCTTGCTCGCGA
AGGTGCACAGGTGCTGGTTATCGAGCGCGGCAATTCTGCTGGCGCGAAGAATGTCACCGGTGGGCGTTTGTATGCACATA
GCCTGGAACGCATCATTCCCGGCTTTGCGGATCAGGCCCCCATTGAACGCATGATCACCCACGAAAAACTCGCCTTTATG
ACCGACAAAGGGGCGATGACGATGGATTATTGCAACGGCGAGGACGCCGCATCGTCGCAGGTTTCTTATTCCGTTTTGCG
CAGTAAATTTGACGCCTGGCTGATGGAGCAGGCCGAAGAGGCGGGGGCGCAACTGATCACCGGTATTCGCGTCGATAACG
TCGTTCAGCGTGATGGCAACGTCGTGGGCGTGGAAGCCGATGGCGATATTCTGGAAGCCAAAGTCGTAATCCTCGCTGAC
GGGGTGAATTCTCTGCTGGCTGAAAAGCTGGGCATGGCCAAACGCGTTGAGGCATCGCATGTTGCTGTCGGCGTGAAGGA
ACTGATCGAACTGCCGAAGTCGGTCATTGAAGATCGTTTCCAGTTACAGGGCAACGAAGGTGCCGCCTGTCTGTTTGCCG
GGGCGCCAACCGATGGTCTGATGGGCGGTGGCTTCCTGTATACGAATGAAACAACCCTTTCCCTGGGGCTGGTCTGTGGA
CTTCATCATCTGAAAGACGCGAAAAAATCGGTCCCGCAAATGCTGGAAGATTTCAAACAGCATCCGGCAGTTGCTCCGCT
GATCGCCGGTGGCAAGCTGGTGGAATATGCCGCACACGTTGTACCCGAGGCGGGAATGAATATGCAGCCTGAACTGGTGG
GCGATGGCGTACTGATTGCCGGAGACGCCGCCGGCATGTGTATGAACCTCGGCTTTACCATCCGGGGTATGGATCTCGCC
ATATCCGCAGGCGAAGCGGCGGCGAAGACGGTGCTTTCGGCGATGAAGCGCGACGATTTTAGCAAGCAGTCGTTGGGGGA
ATACCGTCAGCATCTGGACGAAGGTCCGATGCGCGATATGCGTATGTATCAGAAACTGCCGGCTTTTCTTGATAATCCCC
GCATGTTTACCGCCTATCCCGAAATGGCGGTCAATATCGCGCGCGACCTGTTCACCGTGGATGGCTCCGCTCCGGTGCCG
ATGCGTAAAAAAATCCTGCGCCATGCGAAGAAAGTGGGCTTCATCAACCTGATGAAAGATGGCCTGAAAGGAGTGACCGT
ATTATGA

Upstream 100 bases:

>100_bases
GGCGATGCGCTGAAGATCCTGCCTGCGCTGACGGCTGCCTTAGCGCGATAAACCATTTCGGGCAGGATGCGAAGGTATCC
TGCCGCTGACAGGAGTACGT

Downstream 100 bases:

>100_bases
CATCTCCCGTTAATGTGGACGTCAAACTGGGCGTCAATAAGTTCAATGTGGATGAAGACAGCCCGCACATCATTCTCAAA
ACCGATCCTGATAAACAGGC

Product: putative oxidoreductase FixC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MSEDIFDAIIVGAGLAGSVAALVLAREGAQVLVIERGNSAGAKNVTGGRLYAHSLERIIPGFADQAPIERMITHEKLAFM
TDKGAMTMDYCNGEDAASSQVSYSVLRSKFDAWLMEQAEEAGAQLITGIRVDNVVQRDGNVVGVEADGDILEAKVVILAD
GVNSLLAEKLGMAKRVEASHVAVGVKELIELPKSVIEDRFQLQGNEGAACLFAGAPTDGLMGGGFLYTNETTLSLGLVCG
LHHLKDAKKSVPQMLEDFKQHPAVAPLIAGGKLVEYAAHVVPEAGMNMQPELVGDGVLIAGDAAGMCMNLGFTIRGMDLA
ISAGEAAAKTVLSAMKRDDFSKQSLGEYRQHLDEGPMRDMRMYQKLPAFLDNPRMFTAYPEMAVNIARDLFTVDGSAPVP
MRKKILRHAKKVGFINLMKDGLKGVTVL

Sequences:

>Translated_428_residues
MSEDIFDAIIVGAGLAGSVAALVLAREGAQVLVIERGNSAGAKNVTGGRLYAHSLERIIPGFADQAPIERMITHEKLAFM
TDKGAMTMDYCNGEDAASSQVSYSVLRSKFDAWLMEQAEEAGAQLITGIRVDNVVQRDGNVVGVEADGDILEAKVVILAD
GVNSLLAEKLGMAKRVEASHVAVGVKELIELPKSVIEDRFQLQGNEGAACLFAGAPTDGLMGGGFLYTNETTLSLGLVCG
LHHLKDAKKSVPQMLEDFKQHPAVAPLIAGGKLVEYAAHVVPEAGMNMQPELVGDGVLIAGDAAGMCMNLGFTIRGMDLA
ISAGEAAAKTVLSAMKRDDFSKQSLGEYRQHLDEGPMRDMRMYQKLPAFLDNPRMFTAYPEMAVNIARDLFTVDGSAPVP
MRKKILRHAKKVGFINLMKDGLKGVTVL
>Mature_427_residues
SEDIFDAIIVGAGLAGSVAALVLAREGAQVLVIERGNSAGAKNVTGGRLYAHSLERIIPGFADQAPIERMITHEKLAFMT
DKGAMTMDYCNGEDAASSQVSYSVLRSKFDAWLMEQAEEAGAQLITGIRVDNVVQRDGNVVGVEADGDILEAKVVILADG
VNSLLAEKLGMAKRVEASHVAVGVKELIELPKSVIEDRFQLQGNEGAACLFAGAPTDGLMGGGFLYTNETTLSLGLVCGL
HHLKDAKKSVPQMLEDFKQHPAVAPLIAGGKLVEYAAHVVPEAGMNMQPELVGDGVLIAGDAAGMCMNLGFTIRGMDLAI
SAGEAAAKTVLSAMKRDDFSKQSLGEYRQHLDEGPMRDMRMYQKLPAFLDNPRMFTAYPEMAVNIARDLFTVDGSAPVPM
RKKILRHAKKVGFINLMKDGLKGVTVL

Specific function: Could be part of an electron transfer system required for anaerobic carnitine reduction [H]

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF-QO/fixC family [H]

Homologues:

Organism=Homo sapiens, GI119703746, Length=382, Percent_Identity=26.9633507853403, Blast_Score=113, Evalue=4e-25,
Organism=Escherichia coli, GI1786227, Length=428, Percent_Identity=89.018691588785, Blast_Score=772, Evalue=0.0,
Organism=Escherichia coli, GI1787991, Length=429, Percent_Identity=60.3729603729604, Blast_Score=531, Evalue=1e-152,
Organism=Escherichia coli, GI87082155, Length=431, Percent_Identity=41.5313225058005, Blast_Score=323, Evalue=9e-90,
Organism=Caenorhabditis elegans, GI25144720, Length=444, Percent_Identity=25.9009009009009, Blast_Score=102, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6324932, Length=371, Percent_Identity=26.6846361185984, Blast_Score=97, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24652256, Length=365, Percent_Identity=28.7671232876712, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: 1.5.5.-

Molecular weight: Translated: 45733; Mature: 45601

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEDIFDAIIVGAGLAGSVAALVLAREGAQVLVIERGNSAGAKNVTGGRLYAHSLERIIP
CCHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCC
GFADQAPIERMITHEKLAFMTDKGAMTMDYCNGEDAASSQVSYSVLRSKFDAWLMEQAEE
CCCCCHHHHHHHHHHHHHEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AGAQLITGIRVDNVVQRDGNVVGVEADGDILEAKVVILADGVNSLLAEKLGMAKRVEASH
HHHHHHHCCCHHHHHHCCCCEEEEECCCCEEEEEEEEEECCHHHHHHHHHCHHHHHHHHH
VAVGVKELIELPKSVIEDRFQLQGNEGAACLFAGAPTDGLMGGGFLYTNETTLSLGLVCG
HHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEECCCCCCCCCCCEEEECCCHHHHHHHHH
LHHLKDAKKSVPQMLEDFKQHPAVAPLIAGGKLVEYAAHVVPEAGMNMQPELVGDGVLIA
HHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEE
GDAAGMCMNLGFTIRGMDLAISAGEAAAKTVLSAMKRDDFSKQSLGEYRQHLDEGPMRDM
CCCCCHHEECCEEEECCEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHH
RMYQKLPAFLDNPRMFTAYPEMAVNIARDLFTVDGSAPVPMRKKILRHAKKVGFINLMKD
HHHHHHHHHHCCCCEEEECHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHCCHHHHHHH
GLKGVTVL
CCCCCCCC
>Mature Secondary Structure 
SEDIFDAIIVGAGLAGSVAALVLAREGAQVLVIERGNSAGAKNVTGGRLYAHSLERIIP
CHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCC
GFADQAPIERMITHEKLAFMTDKGAMTMDYCNGEDAASSQVSYSVLRSKFDAWLMEQAEE
CCCCCHHHHHHHHHHHHHEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AGAQLITGIRVDNVVQRDGNVVGVEADGDILEAKVVILADGVNSLLAEKLGMAKRVEASH
HHHHHHHCCCHHHHHHCCCCEEEEECCCCEEEEEEEEEECCHHHHHHHHHCHHHHHHHHH
VAVGVKELIELPKSVIEDRFQLQGNEGAACLFAGAPTDGLMGGGFLYTNETTLSLGLVCG
HHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEECCCCCCCCCCCEEEECCCHHHHHHHHH
LHHLKDAKKSVPQMLEDFKQHPAVAPLIAGGKLVEYAAHVVPEAGMNMQPELVGDGVLIA
HHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEE
GDAAGMCMNLGFTIRGMDLAISAGEAAAKTVLSAMKRDDFSKQSLGEYRQHLDEGPMRDM
CCCCCHHEECCEEEECCEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHH
RMYQKLPAFLDNPRMFTAYPEMAVNIARDLFTVDGSAPVPMRKKILRHAKKVGFINLMKD
HHHHHHHHHHCCCCEEEECHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHCCHHHHHHH
GLKGVTVL
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]