Click here to switch to the map view.

The map label for this gene is gluQ [H]

Identifier: 194733989

GI number: 194733989

Start: 222065

End: 223006

Strand: Reverse

Name: gluQ [H]

Synonym: SeSA_A0213

Alternate gene names: 194733989

Gene position: 223006-222065 (Counterclockwise)

Preceding gene: 194734478

Following gene: 194737669

Centisome position: 4.74

GC content: 57.86

Gene sequence:

>942_bases
ATGACAGGCGGGAGTTTTCCCGCCTTATTCTTTATTGCCCGCAGCATGACTGACTCACACTATATTGGCCGTTTCGCGCC
GTCGCCATCCGGCGAACTGCATTTCGGCTCGTTAATCGCCGCCCTCGGCAGCTATCTACAAGCCCGTGCGCAACGCGGAA
TTTGGCGCGTTCGCATAGAGGATATCGACCCCCCACGTGAAGTTCCCGGTGCCGCAGCGACCATTCTGCGCCAGCTGGAA
CATTACGGCCTGCACTGGGATGGCGAGGTCTTATGGCAATCACAGCGTCATGAGGCTTATCGCGAGGCGCTGGCCTGGCT
TCACGAGCAGGGACTGAGCTACTACTGCACTTGCCCCCGCTCGCGCATTCAACGTCTGGGCGGTATTTACGACGGCCATT
GCCGGACGTTATACCACGGGCCGGAGAATGCCGCCGTCAGAATTAAACAGCAGCATCCGGTGATGCGTTTCCATGATGCC
TTGCGCGGCGACATCCAGGCTGACCCACAGCTGGCGAGCGAAGATTTTATTATCCACCGCCGCGACGGACTGTTTGCTTA
TAATCTGGCCGTGGTGGTCGACGATCATTTTCAGGGGGTGACGGAGATCGTCCGCGGCGCAGATTTAATCGAACCCACTG
TCCGACAACTTTCGCTGTATAAACAGTTTGGCTGGCGTGCGCCAGGTTACGTGCACCTTCCGCTGGCGCTCAACGAACAA
GGCGCTAAACTTTCCAAGCAAAATCATGCCCCTGCGCTTGCGACAGGCGATCCGCGCCCGGTACTGGTCCAGGCATTGCG
CTTTTTAGGCCAACGCGACGTCGTAGCGTGGCAGGAGATGTCTGTTGAGGAGTTGCTGCGCTTTGCGGTGGAGCACTGGA
GGCTTGCAGCCGTACCCACATCGGCTAATGTAAATCCGGCATTCTCAAATGCGTCTCGCTGA

Upstream 100 bases:

>100_bases
AAGCGCGTCCAACAGCCGATCTGTGCATCGACTGCAAAACGCTGGCTGAAATTCGCGAAAAACAGATGGCGGGTTAATCC
CGTTCGTTTCTACCCTATTT

Downstream 100 bases:

>100_bases
GCTATGATTAGCCGCTATTTTTGCTCATCGTCTTTCGCATTGCTGCGGCGTTAATGATGCTTACAGCCCAGGTCGCGTTG
TTCTCTTACGCCCGTCTGCC

Product: glutamyl-Q tRNA(Asp) synthetase

Products: NA

Alternate protein names: Glu-Q-RSs [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MTGGSFPALFFIARSMTDSHYIGRFAPSPSGELHFGSLIAALGSYLQARAQRGIWRVRIEDIDPPREVPGAAATILRQLE
HYGLHWDGEVLWQSQRHEAYREALAWLHEQGLSYYCTCPRSRIQRLGGIYDGHCRTLYHGPENAAVRIKQQHPVMRFHDA
LRGDIQADPQLASEDFIIHRRDGLFAYNLAVVVDDHFQGVTEIVRGADLIEPTVRQLSLYKQFGWRAPGYVHLPLALNEQ
GAKLSKQNHAPALATGDPRPVLVQALRFLGQRDVVAWQEMSVEELLRFAVEHWRLAAVPTSANVNPAFSNASR

Sequences:

>Translated_313_residues
MTGGSFPALFFIARSMTDSHYIGRFAPSPSGELHFGSLIAALGSYLQARAQRGIWRVRIEDIDPPREVPGAAATILRQLE
HYGLHWDGEVLWQSQRHEAYREALAWLHEQGLSYYCTCPRSRIQRLGGIYDGHCRTLYHGPENAAVRIKQQHPVMRFHDA
LRGDIQADPQLASEDFIIHRRDGLFAYNLAVVVDDHFQGVTEIVRGADLIEPTVRQLSLYKQFGWRAPGYVHLPLALNEQ
GAKLSKQNHAPALATGDPRPVLVQALRFLGQRDVVAWQEMSVEELLRFAVEHWRLAAVPTSANVNPAFSNASR
>Mature_312_residues
TGGSFPALFFIARSMTDSHYIGRFAPSPSGELHFGSLIAALGSYLQARAQRGIWRVRIEDIDPPREVPGAAATILRQLEH
YGLHWDGEVLWQSQRHEAYREALAWLHEQGLSYYCTCPRSRIQRLGGIYDGHCRTLYHGPENAAVRIKQQHPVMRFHDAL
RGDIQADPQLASEDFIIHRRDGLFAYNLAVVVDDHFQGVTEIVRGADLIEPTVRQLSLYKQFGWRAPGYVHLPLALNEQG
AKLSKQNHAPALATGDPRPVLVQALRFLGQRDVVAWQEMSVEELLRFAVEHWRLAAVPTSANVNPAFSNASR

Specific function: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble positi

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily [H]

Homologues:

Organism=Homo sapiens, GI134288884, Length=249, Percent_Identity=35.3413654618474, Blast_Score=137, Evalue=9e-33,
Organism=Escherichia coli, GI226510925, Length=303, Percent_Identity=79.5379537953795, Blast_Score=505, Evalue=1e-144,
Organism=Escherichia coli, GI1788743, Length=301, Percent_Identity=32.2259136212625, Blast_Score=132, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI71993394, Length=251, Percent_Identity=33.8645418326693, Blast_Score=119, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6324540, Length=269, Percent_Identity=33.0855018587361, Blast_Score=139, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24665321, Length=249, Percent_Identity=34.5381526104418, Blast_Score=132, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022380
- InterPro:   IPR000924
- InterPro:   IPR020058
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c [H]

EC number: NA

Molecular weight: Translated: 35258; Mature: 35127

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGGSFPALFFIARSMTDSHYIGRFAPSPSGELHFGSLIAALGSYLQARAQRGIWRVRIE
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEE
DIDPPREVPGAAATILRQLEHYGLHWDGEVLWQSQRHEAYREALAWLHEQGLSYYCTCPR
CCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCH
SRIQRLGGIYDGHCRTLYHGPENAAVRIKQQHPVMRFHDALRGDIQADPQLASEDFIIHR
HHHHHHCCCCCCCEEEEEECCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCEEEEE
RDGLFAYNLAVVVDDHFQGVTEIVRGADLIEPTVRQLSLYKQFGWRAPGYVHLPLALNEQ
CCCEEEEEEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCC
GAKLSKQNHAPALATGDPRPVLVQALRFLGQRDVVAWQEMSVEELLRFAVEHWRLAAVPT
CCHHHHCCCCCEEECCCCCHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHEEEECCC
SANVNPAFSNASR
CCCCCCCCCCCCC
>Mature Secondary Structure 
TGGSFPALFFIARSMTDSHYIGRFAPSPSGELHFGSLIAALGSYLQARAQRGIWRVRIE
CCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEE
DIDPPREVPGAAATILRQLEHYGLHWDGEVLWQSQRHEAYREALAWLHEQGLSYYCTCPR
CCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCH
SRIQRLGGIYDGHCRTLYHGPENAAVRIKQQHPVMRFHDALRGDIQADPQLASEDFIIHR
HHHHHHCCCCCCCEEEEEECCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCEEEEE
RDGLFAYNLAVVVDDHFQGVTEIVRGADLIEPTVRQLSLYKQFGWRAPGYVHLPLALNEQ
CCCEEEEEEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCC
GAKLSKQNHAPALATGDPRPVLVQALRFLGQRDVVAWQEMSVEELLRFAVEHWRLAAVPT
CCHHHHCCCCCEEECCCCCHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHEEEECCC
SANVNPAFSNASR
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA