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The map label for this gene is fimC [H]

Identifier: 194733946

GI number: 194733946

Start: 4703738

End: 4704421

Strand: Reverse

Name: fimC [H]

Synonym: SeSA_A4845

Alternate gene names: 194733946

Gene position: 4704421-4703738 (Counterclockwise)

Preceding gene: 194737130

Following gene: 194737814

Centisome position: 99.9

GC content: 46.2

Gene sequence:

>684_bases
ATGAAACACATAAAGAAATCCGTGTTGGTCGTATTACTGACAAGCCATGTTGCCCATGCCAGCATTGTTGTTGGCGGAAC
CCGACTGGTTTTCGACGGCAATAATGATGATTCGTCAATCAATGTAGAGAATAAAGACAGCAAAGCGAATCTTGTTCAGT
CATGGTTATCGGTTGCCGATCCCCAGGTCACAAATAAGCAGGCGTTTATTATCACCCCGCCTCTTTTTCGCCTTGATGCC
GGGCAAAAGAACAGCATTCGGGTTATTCGCTCTGGCGCCCCCCTACCTGCAGATCGGGAATCTATGTACTGGCTCAATAT
TAAGGGTATTCCTTCTATTGATGATAATGCCTCCGCGAACCGCGTGGAAATCTCCATTAATACCCAAATAAAGCTTATAT
ATCGGCCGCCAGCATTAACAAAATCGACGCCTGATAGCCAGAGCCAACAATTAAAATGGCAGACGGCAGGTGATGTTATT
ACCGTAAATAACCCCACGCCCTATTATATGAACTTTGCCAGTGTGACGCTTAACAGCCATGAAGTGAAATCAGCGACCTT
CGTTCCGCCAAAATCATCAGCGTCATTTAAATTGAGTTCTACTGCCGCCCCTCATGGCACGGTAACGTGGCGATTAATCA
GCGATTATGGGATGAGTTTAGAGCCGCATTCCGGTTCATTCTAG

Upstream 100 bases:

>100_bases
CAGGTTACGTATACCGTTTCGTATCAGTAAGGCATTCTCATCCTGATGTGGACAGGCAGGATGCCAGTCCATAGCGTAAA
ACATCTTTACAGAGTAAAAA

Downstream 100 bases:

>100_bases
CCATTAACGACTTCACTTTACTTTTACCCTTTCAGGACTTTTACTGTGCAATTCTCCAGAGTAGAGCCCCGTTCTCAATT
AGCGTTATCGTTTCTCTTTA

Product: pili assembly chaperone

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MKHIKKSVLVVLLTSHVAHASIVVGGTRLVFDGNNDDSSINVENKDSKANLVQSWLSVADPQVTNKQAFIITPPLFRLDA
GQKNSIRVIRSGAPLPADRESMYWLNIKGIPSIDDNASANRVEISINTQIKLIYRPPALTKSTPDSQSQQLKWQTAGDVI
TVNNPTPYYMNFASVTLNSHEVKSATFVPPKSSASFKLSSTAAPHGTVTWRLISDYGMSLEPHSGSF

Sequences:

>Translated_227_residues
MKHIKKSVLVVLLTSHVAHASIVVGGTRLVFDGNNDDSSINVENKDSKANLVQSWLSVADPQVTNKQAFIITPPLFRLDA
GQKNSIRVIRSGAPLPADRESMYWLNIKGIPSIDDNASANRVEISINTQIKLIYRPPALTKSTPDSQSQQLKWQTAGDVI
TVNNPTPYYMNFASVTLNSHEVKSATFVPPKSSASFKLSSTAAPHGTVTWRLISDYGMSLEPHSGSF
>Mature_227_residues
MKHIKKSVLVVLLTSHVAHASIVVGGTRLVFDGNNDDSSINVENKDSKANLVQSWLSVADPQVTNKQAFIITPPLFRLDA
GQKNSIRVIRSGAPLPADRESMYWLNIKGIPSIDDNASANRVEISINTQIKLIYRPPALTKSTPDSQSQQLKWQTAGDVI
TVNNPTPYYMNFASVTLNSHEVKSATFVPPKSSASFKLSSTAAPHGTVTWRLISDYGMSLEPHSGSF

Specific function: Required for the biogenesis of type 1 fimbriae. Binds and interact with fimH [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Ig-like (immunoglobulin-like) domain [H]

Homologues:

Organism=Escherichia coli, GI1790771, Length=213, Percent_Identity=32.3943661971831, Blast_Score=133, Evalue=8e-33,
Organism=Escherichia coli, GI1786743, Length=224, Percent_Identity=32.1428571428571, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1789532, Length=219, Percent_Identity=30.5936073059361, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787171, Length=218, Percent_Identity=32.1100917431193, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1786333, Length=237, Percent_Identity=30.379746835443, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786936, Length=186, Percent_Identity=30.6451612903226, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87081806, Length=212, Percent_Identity=31.1320754716981, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1788677, Length=206, Percent_Identity=31.0679611650485, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1788428, Length=225, Percent_Identity=25.7777777777778, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1789609, Length=224, Percent_Identity=26.3392857142857, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87082203, Length=228, Percent_Identity=24.5614035087719, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008962
- InterPro:   IPR001829
- InterPro:   IPR016148
- InterPro:   IPR018046
- InterPro:   IPR016147 [H]

Pfam domain/function: PF02753 Pili_assembly_C; PF00345 Pili_assembly_N [H]

EC number: NA

Molecular weight: Translated: 24787; Mature: 24787

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: PS00635 PILI_CHAPERONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHIKKSVLVVLLTSHVAHASIVVGGTRLVFDGNNDDSSINVENKDSKANLVQSWLSVAD
CCCHHHHHEEEEEHHCCCEEEEEECCEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHCC
PQVTNKQAFIITPPLFRLDAGQKNSIRVIRSGAPLPADRESMYWLNIKGIPSIDDNASAN
CCCCCCEEEEECCCCEEECCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCC
RVEISINTQIKLIYRPPALTKSTPDSQSQQLKWQTAGDVITVNNPTPYYMNFASVTLNSH
EEEEEECCEEEEEECCCCCCCCCCCCCHHEEEEEECCCEEEECCCCCEEEEEEEEEECCC
EVKSATFVPPKSSASFKLSSTAAPHGTVTWRLISDYGMSLEPHSGSF
CCCEEEECCCCCCCCEEEECCCCCCCCEEEEEEECCCCEECCCCCCC
>Mature Secondary Structure
MKHIKKSVLVVLLTSHVAHASIVVGGTRLVFDGNNDDSSINVENKDSKANLVQSWLSVAD
CCCHHHHHEEEEEHHCCCEEEEEECCEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHCC
PQVTNKQAFIITPPLFRLDAGQKNSIRVIRSGAPLPADRESMYWLNIKGIPSIDDNASAN
CCCCCCEEEEECCCCEEECCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCC
RVEISINTQIKLIYRPPALTKSTPDSQSQQLKWQTAGDVITVNNPTPYYMNFASVTLNSH
EEEEEECCEEEEEECCCCCCCCCCCCCHHEEEEEECCCEEEECCCCCEEEEEEEEEECCC
EVKSATFVPPKSSASFKLSSTAAPHGTVTWRLISDYGMSLEPHSGSF
CCCEEEECCCCCCCCEEEECCCCCCCCEEEEEEECCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]