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The map label for this gene is murG

Identifier: 194335051

GI number: 194335051

Start: 2440930

End: 2442027

Strand: Reverse

Name: murG

Synonym: Paes_2263

Alternate gene names: 194335051

Gene position: 2442027-2440930 (Counterclockwise)

Preceding gene: 194335052

Following gene: 194335050

Centisome position: 97.18

GC content: 56.38

Gene sequence:

>1098_bases
ATGAATATTCTGTTTGCAGGAGGAGGGACCGGAGGGCATCTCTATCCGGCAGTTGCCATGGCAGAGCGCCTCGAGCAGCT
CTATCCGGGGACGACCGTCGCTTTTGTCGGTACCGAGCGGGGCATTGAGGCGACCGAGATTCCGCGCCTCGGTTACCGGC
TGCATCTGCTTGACGTCAGAGGGTTCCGGCGGGGCTTTTCCTTTTCAGATATGCTCAATAATGCAGGAGTGCTTCTTGAT
TTTGTTCGGGCTGTCGTCAAGGCTGCCGGGATTATTCGTGCCGAACAACCCGATGTTGTCGTCGGGACAGGCGGGTTTGT
CAGCGGCCCGCTGCTTGCCGCGGCAGAGCTGATGGGGCGCAAGACACTTATTCAGGAGCAGAACGCTTTTCCCGGGGTGA
CTACCCGGTTTCTTGCAGCATTTGCGACTGAAGTGCATCTTTCATTCGAAGAGAGCCGGAAATTTTTTCGGCGAAAACAA
GGTGTTTTCGTGACCGGTAATCCTGCAAGATCGTTTACAGGGATTGATCAGGCAGAGGCTCAGTCTTTTTTCGGTCTTCA
GCCCGGTCTGCCGACGCTGCTTGTTTTCGGGGGAAGCAGAGGTGCCCGTTCGATCAATAATGCGGTGAAAACATGGATTT
CCGGTGCGGCTGGCAAGGCCAATATTATCTGGCAGACGGGCAGCCTTGATGACGAACGTCTTCGAAAGGAGGTAGAGCCG
TCCGCTACGCTCTGGATCGGGCCCTATATCAATGACATGCGTATGGCCTATGGCGCGGCTGATCTCGTGCTCTGCCGGGC
AGGTGCTTCGACGCTGGCAGAACTGACCAACCTCGGAAAGGCTTCGGTACTTGTTCCCTACCCTTATGCTACCGGAAACC
ATCAGTTTTTCAATGCCAAAGCGCTGGTCGATGCAGGTGCTGCCGAGCTTGTCGCCGATGCCGATATCGCTCTCGATCAG
TCGCGAACGAAGGTTTTCAGCATTCTTGCCGACCCGGAGCTCCGTCTGCGCATGAGGGAAGCCTGCCGCAAGGAGGGACG
GCCGGAGGCCGCTTTGGATCTTGCAGGAAGAATTGCCGGGCTGGCTAACATTAAGTGA

Upstream 100 bases:

>100_bases
TCTTTAACTCGATCGGGGTCGGTATTCTGGTCAGTATTTCAAGAAACCGCAAACAGCAGGATCTGCAAGATTCAGCCGAG
ACTATGGAGGGTCAGGGGAT

Downstream 100 bases:

>100_bases
GGAAACAGGGTGGAATTAGGAAAAACAAAATGTGTGCATATCGTCGGAATCGGCGGGGCTGGAATGAGCGCAATTGCTGA
ACTGCTCTTGAAATCGGGGT

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MNILFAGGGTGGHLYPAVAMAERLEQLYPGTTVAFVGTERGIEATEIPRLGYRLHLLDVRGFRRGFSFSDMLNNAGVLLD
FVRAVVKAAGIIRAEQPDVVVGTGGFVSGPLLAAAELMGRKTLIQEQNAFPGVTTRFLAAFATEVHLSFEESRKFFRRKQ
GVFVTGNPARSFTGIDQAEAQSFFGLQPGLPTLLVFGGSRGARSINNAVKTWISGAAGKANIIWQTGSLDDERLRKEVEP
SATLWIGPYINDMRMAYGAADLVLCRAGASTLAELTNLGKASVLVPYPYATGNHQFFNAKALVDAGAAELVADADIALDQ
SRTKVFSILADPELRLRMREACRKEGRPEAALDLAGRIAGLANIK

Sequences:

>Translated_365_residues
MNILFAGGGTGGHLYPAVAMAERLEQLYPGTTVAFVGTERGIEATEIPRLGYRLHLLDVRGFRRGFSFSDMLNNAGVLLD
FVRAVVKAAGIIRAEQPDVVVGTGGFVSGPLLAAAELMGRKTLIQEQNAFPGVTTRFLAAFATEVHLSFEESRKFFRRKQ
GVFVTGNPARSFTGIDQAEAQSFFGLQPGLPTLLVFGGSRGARSINNAVKTWISGAAGKANIIWQTGSLDDERLRKEVEP
SATLWIGPYINDMRMAYGAADLVLCRAGASTLAELTNLGKASVLVPYPYATGNHQFFNAKALVDAGAAELVADADIALDQ
SRTKVFSILADPELRLRMREACRKEGRPEAALDLAGRIAGLANIK
>Mature_365_residues
MNILFAGGGTGGHLYPAVAMAERLEQLYPGTTVAFVGTERGIEATEIPRLGYRLHLLDVRGFRRGFSFSDMLNNAGVLLD
FVRAVVKAAGIIRAEQPDVVVGTGGFVSGPLLAAAELMGRKTLIQEQNAFPGVTTRFLAAFATEVHLSFEESRKFFRRKQ
GVFVTGNPARSFTGIDQAEAQSFFGLQPGLPTLLVFGGSRGARSINNAVKTWISGAAGKANIIWQTGSLDDERLRKEVEP
SATLWIGPYINDMRMAYGAADLVLCRAGASTLAELTNLGKASVLVPYPYATGNHQFFNAKALVDAGAAELVADADIALDQ
SRTKVFSILADPELRLRMREACRKEGRPEAALDLAGRIAGLANIK

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=371, Percent_Identity=30.7277628032345, Blast_Score=142, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_PROA2 (B4S6Q9)

Other databases:

- EMBL:   CP001108
- RefSeq:   YP_002016911.1
- ProteinModelPortal:   B4S6Q9
- SMR:   B4S6Q9
- GeneID:   6459573
- GenomeReviews:   CP001108_GR
- KEGG:   paa:Paes_2263
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- ProtClustDB:   PRK00726
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 39191; Mature: 39191

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILFAGGGTGGHLYPAVAMAERLEQLYPGTTVAFVGTERGIEATEIPRLGYRLHLLDVR
CEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHCCCCCCEEEEEEECH
GFRRGFSFSDMLNNAGVLLDFVRAVVKAAGIIRAEQPDVVVGTGGFVSGPLLAAAELMGR
HHHCCCCHHHHHCCCHHHHHHHHHHHHHHHCEECCCCCEEEECCCCCCCHHHHHHHHHHH
KTLIQEQNAFPGVTTRFLAAFATEVHLSFEESRKFFRRKQGVFVTGNPARSFTGIDQAEA
HHHHHHCCCCCCHHHHHHHHHHHHHEECHHHHHHHHHHHCCEEEECCCCCCCCCCCHHHH
QSFFGLQPGLPTLLVFGGSRGARSINNAVKTWISGAAGKANIIWQTGSLDDERLRKEVEP
HHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHCCC
SATLWIGPYINDMRMAYGAADLVLCRAGASTLAELTNLGKASVLVPYPYATGNHQFFNAK
CCEEEECCCHHHHHHHHCCHHHEEECCCHHHHHHHHCCCCCEEEEECCCCCCCCEEEEHH
ALVDAGAAELVADADIALDQSRTKVFSILADPELRLRMREACRKEGRPEAALDLAGRIAG
HHHHCCHHHHHCCCHHHHCCCHHHEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LANIK
HCCCC
>Mature Secondary Structure
MNILFAGGGTGGHLYPAVAMAERLEQLYPGTTVAFVGTERGIEATEIPRLGYRLHLLDVR
CEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHCCCCCCEEEEEEECH
GFRRGFSFSDMLNNAGVLLDFVRAVVKAAGIIRAEQPDVVVGTGGFVSGPLLAAAELMGR
HHHCCCCHHHHHCCCHHHHHHHHHHHHHHHCEECCCCCEEEECCCCCCCHHHHHHHHHHH
KTLIQEQNAFPGVTTRFLAAFATEVHLSFEESRKFFRRKQGVFVTGNPARSFTGIDQAEA
HHHHHHCCCCCCHHHHHHHHHHHHHEECHHHHHHHHHHHCCEEEECCCCCCCCCCCHHHH
QSFFGLQPGLPTLLVFGGSRGARSINNAVKTWISGAAGKANIIWQTGSLDDERLRKEVEP
HHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHCCC
SATLWIGPYINDMRMAYGAADLVLCRAGASTLAELTNLGKASVLVPYPYATGNHQFFNAK
CCEEEECCCHHHHHHHHCCHHHEEECCCHHHHHHHHCCCCCEEEEECCCCCCCCEEEEHH
ALVDAGAAELVADADIALDQSRTKVFSILADPELRLRMREACRKEGRPEAALDLAGRIAG
HHHHCCHHHHHCCCHHHHCCCHHHEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LANIK
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA