Click here to switch to the map view.

The map label for this gene is murB [H]

Identifier: 194335049

GI number: 194335049

Start: 2438583

End: 2439515

Strand: Reverse

Name: murB [H]

Synonym: Paes_2261

Alternate gene names: 194335049

Gene position: 2439515-2438583 (Counterclockwise)

Preceding gene: 194335050

Following gene: 194335048

Centisome position: 97.08

GC content: 52.52

Gene sequence:

>933_bases
ATGCTGAGTACTGAAGAGCTGTTACGGACCATACGGGGTTCAATTAGTATCGGGGAGCCGATGAGTGAGCATACTTCGCT
CAAGATCGGCGGATCGGCGGATTTTTTTATAGATCCGCTTGATCGGGACGATTTTTGTGAGGCACTCCGATTTTTCTCCC
GTCATAACCTTCCCTGTACCATTATCGGCAGAGGTTCGAACATGCTGGTTCATGATGACGGTATTCGGGGGGCAGTGATC
AGAACCCCTCGTGCCTTGGGGAAGCTGACTGTCAAAAAAGAGAGTGTTGTTGTTGAGGCGGGAGTTCCTCTTCCTTTGCT
GGCGGAAAAAACTTTTGCCGCTTCTCTGGGAGGGATTGAACTGCTTCAGGGGATCCCGGGAACGACGGGCGGAGCCCTGA
TGATGAACGCCGGGGCATGGGGGCAGGAGCTGTTCGATGTTGTATCATGGGTAGAAGTGCTTCGTGACGGGACATTGATG
ACGCTGCAGCGGGAGGAGATCCGGTTTGGTTACAGGTATGGCGGCCTGGACGACAGTGTGATCATTTCGGCTGGACTCAA
ACTCAAAAAGCTCTCCGCTGCATCTGTCAGGGAGCGTTTGGTCGTTCTGCAGGAATCCAGAAAAAAGCGGATGGAGTCAC
AGCCTTTATCGCAGCCCAATGCCGGAAGTATATTCCGTAACCCGGATCCGGTCGGCCATCCTGAAGCAATGAGTGCCGGG
AAAATGATCGATCTGTGCGGTCTCAAAGGGACCCGTCGAGGTGATGCGGTTATTTCCGACGTTCACGCAAATTTTATTGT
CAACGCCGGTTCGGCAAGAGCTGCCGATATGATAGAGCTGATCTCTGTTGCGCGCAATGCGGTTCAGTCGACTTTTGGCG
TTTGTCTCGATCTTGAAATCAAGCTGCTTGGATTTGAAAACGCACTCTGCTGA

Upstream 100 bases:

>100_bases
GTTCCTGGAATGCTGATGCTTTTTATGGGGGCTGGTGATATTACAGGCATATCTGTCAGTATGGCGGATTTCTGCACGAA
ACGATCTTGAAAGGAATGGA

Downstream 100 bases:

>100_bases
TGCCCGATTTTGTTTTTGACGATCAGGGGGTCGAGCAGCAGGACAGCAATGACCGCGCTCAGGGACCCGGAGATTCCGGA
CCGTCGGGTGATGAAGGCCG

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MLSTEELLRTIRGSISIGEPMSEHTSLKIGGSADFFIDPLDRDDFCEALRFFSRHNLPCTIIGRGSNMLVHDDGIRGAVI
RTPRALGKLTVKKESVVVEAGVPLPLLAEKTFAASLGGIELLQGIPGTTGGALMMNAGAWGQELFDVVSWVEVLRDGTLM
TLQREEIRFGYRYGGLDDSVIISAGLKLKKLSAASVRERLVVLQESRKKRMESQPLSQPNAGSIFRNPDPVGHPEAMSAG
KMIDLCGLKGTRRGDAVISDVHANFIVNAGSARAADMIELISVARNAVQSTFGVCLDLEIKLLGFENALC

Sequences:

>Translated_310_residues
MLSTEELLRTIRGSISIGEPMSEHTSLKIGGSADFFIDPLDRDDFCEALRFFSRHNLPCTIIGRGSNMLVHDDGIRGAVI
RTPRALGKLTVKKESVVVEAGVPLPLLAEKTFAASLGGIELLQGIPGTTGGALMMNAGAWGQELFDVVSWVEVLRDGTLM
TLQREEIRFGYRYGGLDDSVIISAGLKLKKLSAASVRERLVVLQESRKKRMESQPLSQPNAGSIFRNPDPVGHPEAMSAG
KMIDLCGLKGTRRGDAVISDVHANFIVNAGSARAADMIELISVARNAVQSTFGVCLDLEIKLLGFENALC
>Mature_310_residues
MLSTEELLRTIRGSISIGEPMSEHTSLKIGGSADFFIDPLDRDDFCEALRFFSRHNLPCTIIGRGSNMLVHDDGIRGAVI
RTPRALGKLTVKKESVVVEAGVPLPLLAEKTFAASLGGIELLQGIPGTTGGALMMNAGAWGQELFDVVSWVEVLRDGTLM
TLQREEIRFGYRYGGLDDSVIISAGLKLKKLSAASVRERLVVLQESRKKRMESQPLSQPNAGSIFRNPDPVGHPEAMSAG
KMIDLCGLKGTRRGDAVISDVHANFIVNAGSARAADMIELISVARNAVQSTFGVCLDLEIKLLGFENALC

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=328, Percent_Identity=27.7439024390244, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 33436; Mature: 33436

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSTEELLRTIRGSISIGEPMSEHTSLKIGGSADFFIDPLDRDDFCEALRFFSRHNLPCT
CCCHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCEEECCCCCHHHHHHHHHHHHCCCCEE
IIGRGSNMLVHDDGIRGAVIRTPRALGKLTVKKESVVVEAGVPLPLLAEKTFAASLGGIE
EEECCCEEEEECCCCCEEEEECCHHHHHEEEECCEEEEECCCCCCHHHHHHHHHHCCCHH
LLQGIPGTTGGALMMNAGAWGQELFDVVSWVEVLRDGTLMTLQREEIRFGYRYGGLDDSV
HHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHEEEEECCCCCCE
IISAGLKLKKLSAASVRERLVVLQESRKKRMESQPLSQPNAGSIFRNPDPVGHPEAMSAG
EEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHCCC
KMIDLCGLKGTRRGDAVISDVHANFIVNAGSARAADMIELISVARNAVQSTFGVCLDLEI
CEEEECCCCCCCCCCHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCEEEEEEE
KLLGFENALC
EEEECCCCCC
>Mature Secondary Structure
MLSTEELLRTIRGSISIGEPMSEHTSLKIGGSADFFIDPLDRDDFCEALRFFSRHNLPCT
CCCHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCEEECCCCCHHHHHHHHHHHHCCCCEE
IIGRGSNMLVHDDGIRGAVIRTPRALGKLTVKKESVVVEAGVPLPLLAEKTFAASLGGIE
EEECCCEEEEECCCCCEEEEECCHHHHHEEEECCEEEEECCCCCCHHHHHHHHHHCCCHH
LLQGIPGTTGGALMMNAGAWGQELFDVVSWVEVLRDGTLMTLQREEIRFGYRYGGLDDSV
HHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHEEEEECCCCCCE
IISAGLKLKKLSAASVRERLVVLQESRKKRMESQPLSQPNAGSIFRNPDPVGHPEAMSAG
EEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHCCC
KMIDLCGLKGTRRGDAVISDVHANFIVNAGSARAADMIELISVARNAVQSTFGVCLDLEI
CEEEECCCCCCCCCCHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCEEEEEEE
KLLGFENALC
EEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA