Click here to switch to the map view.

The map label for this gene is yrbI [C]

Identifier: 194334957

GI number: 194334957

Start: 2342546

End: 2343115

Strand: Reverse

Name: yrbI [C]

Synonym: Paes_2168

Alternate gene names: 194334957

Gene position: 2343115-2342546 (Counterclockwise)

Preceding gene: 194334958

Following gene: 194334950

Centisome position: 93.24

GC content: 50.53

Gene sequence:

>570_bases
GTGTCAGGAATTAATTATTTCGGTATTCAATTGTCGGCAGGAGATCATTCCGAGCGTCTGACGACGGCTATTTCCCGGGT
TAAAGCGCTGATGTTTTCTGTTGACGGAGTTCTCACAGGAGGCCAGATAACGTTTGACGGGAGCGGGGAGGAGATATGCT
CCTGTTATGGACGCGATGCTCTGGCTATCAGAGCGGCGCAGGAAAGCGGGTTGCAGATCGCGGCATTTTCTGCACGCCAG
AGCAATGCTTTACGCTCTCTTCTTGAAGAGATCGGGATTCGTAATGCCTTCCTTGGATGTTCGAATACGATGGAGGCGTA
TGAAGCGTTTACGTCATCCTGCGGTCTGGAGGATGACGAGTGTGCCTATATCGCCGACGATGTAGGCGATATTCCTATTC
TTGAAAAAGTTGCCTTGTCGGTTACCCCGATCGACGGTATTGAATATCTCCGCAACCGGGTTTCCTACATTTCAGGATTT
GAGGGCGGAAAAGGGTGTGTCCGCGAAATGATCGAGCTTATTCTGCAGCAGCAGGGTAAGTGGACATTCAGCGATCACTG
CGTTCTTTGA

Upstream 100 bases:

>100_bases
CAACCCAGATTGCACTCAGGGACTTTCCCGGCCTGTTTTTGCAGCTTCAGAAGCTGCATGCCTGCCTACAATCTTTGTAA
CCATTTAAAAGAACAGTGTT

Downstream 100 bases:

>100_bases
GTTCCGTTGCAATTGATGAAGTTGACTTCATCCGTACGTCAACTTCATCAATATTAATCAGCACGCTCCAGCTTCTGTTC
TTCAAGCCACTGTTTTGCCG

Product: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 189; Mature: 188

Protein sequence:

>189_residues
MSGINYFGIQLSAGDHSERLTTAISRVKALMFSVDGVLTGGQITFDGSGEEICSCYGRDALAIRAAQESGLQIAAFSARQ
SNALRSLLEEIGIRNAFLGCSNTMEAYEAFTSSCGLEDDECAYIADDVGDIPILEKVALSVTPIDGIEYLRNRVSYISGF
EGGKGCVREMIELILQQQGKWTFSDHCVL

Sequences:

>Translated_189_residues
MSGINYFGIQLSAGDHSERLTTAISRVKALMFSVDGVLTGGQITFDGSGEEICSCYGRDALAIRAAQESGLQIAAFSARQ
SNALRSLLEEIGIRNAFLGCSNTMEAYEAFTSSCGLEDDECAYIADDVGDIPILEKVALSVTPIDGIEYLRNRVSYISGF
EGGKGCVREMIELILQQQGKWTFSDHCVL
>Mature_188_residues
SGINYFGIQLSAGDHSERLTTAISRVKALMFSVDGVLTGGQITFDGSGEEICSCYGRDALAIRAAQESGLQIAAFSARQS
NALRSLLEEIGIRNAFLGCSNTMEAYEAFTSSCGLEDDECAYIADDVGDIPILEKVALSVTPIDGIEYLRNRVSYISGFE
GGKGCVREMIELILQQQGKWTFSDHCVL

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=153, Percent_Identity=30.0653594771242, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI2367202, Length=167, Percent_Identity=32.3353293413174, Blast_Score=97, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 20414; Mature: 20283

Theoretical pI: Translated: 4.24; Mature: 4.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGINYFGIQLSAGDHSERLTTAISRVKALMFSVDGVLTGGQITFDGSGEEICSCYGRDA
CCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCEEECCEEEECCCHHHHHHHHCCCC
LAIRAAQESGLQIAAFSARQSNALRSLLEEIGIRNAFLGCSNTMEAYEAFTSSCGLEDDE
EEEEEHHHCCCEEEEECCHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHCCCCCCC
CAYIADDVGDIPILEKVALSVTPIDGIEYLRNRVSYISGFEGGKGCVREMIELILQQQGK
CEEEECCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
WTFSDHCVL
EECCCCCCC
>Mature Secondary Structure 
SGINYFGIQLSAGDHSERLTTAISRVKALMFSVDGVLTGGQITFDGSGEEICSCYGRDA
CCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCEEECCEEEECCCHHHHHHHHCCCC
LAIRAAQESGLQIAAFSARQSNALRSLLEEIGIRNAFLGCSNTMEAYEAFTSSCGLEDDE
EEEEEHHHCCCEEEEECCHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHCCCCCCC
CAYIADDVGDIPILEKVALSVTPIDGIEYLRNRVSYISGFEGGKGCVREMIELILQQQGK
CEEEECCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
WTFSDHCVL
EECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 12639950; 11835514 [H]