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The map label for this gene is obgE

Identifier: 194334875

GI number: 194334875

Start: 2261798

End: 2262781

Strand: Reverse

Name: obgE

Synonym: Paes_2078

Alternate gene names: 194334875

Gene position: 2262781-2261798 (Counterclockwise)

Preceding gene: 194334877

Following gene: 194334874

Centisome position: 90.05

GC content: 51.32

Gene sequence:

>984_bases
GTGAAATTTGTTGATAGTGCAAGGATTGTTGTTAAGGCGGGAGATGGAGGAAATGGATGTGTCAGTTTTCGCCGGGAGAA
ATATGTTCCTAAAGGAGGGCCTGACGGAGGTGACGGAGGACGGGGAGGTCATGTGTATCTTCGTGCCAACAGCCAGTTGG
CGACGCTTCTTGATTTCAGATATAAAAAAAATTATGAGGCCCTGCGTGGCGTTCACGGTCAGGGTTCGAAAAAAGCCGGT
AAGACAGGCAAGGATATTGTAATCAATGTGCCTTGCGGGACGCTGGTCAAAAACAGTGTTTCAGGCGAGGTTATCTGTGA
TCTTGTCGAAGACGGAGAGGAGTTTCTTCTTGCCCGCGGGGGCGATGGCGGAAGAGGGAACCCTCATTTTACGACATCTA
CCCGCCAGGCACCGCGCTATGCTGAGCCCGGGGGGAAAGGTGAAGAGTTGAAGGTCGATCTGGAATTGAAGCTGATGGCC
GACGTTGGGCTGGTAGGATTTCCGAACGCTGGAAAATCCACTCTGATTTCAGTGCTGAGCGCGGCCAGACCAAAAATTGC
TGATTATCCGTTTACGACGCTGGTTCCCAATCTCGGTATTGTGCAGTACGGGGAGTACAAGTCTTTCGTCATGGCCGATA
TTCCCGGTATTATTGAGGGGGCCGCGGAAGGTAAAGGTCTCGGTATTCAGTTTCTTCGTCATATCGAACGGACAAAAGTG
CTTGCTGTCCTTGTCTCGGGTGACGGAGAGGATCCTGTTGGGGAGTACCGTCTTCTTCTGGGAGAGATGGAGCGTTTCGA
TCCGGCGCTTCTGCAGAAGCCCCGGATCATCGTCGTGACTAAAATGGATGTTGTCGATGAAGCGTTCAGTCTTCCTGATT
TCGAAGACGATGTTCCGCTGATCCCTGTTTCGAGCATTACCCGTTCAGGGCTTGAGGAGTTGCGTAACGCGCTTTGGAAT
ACCATTAACCCTTCTATCCCTTAA

Upstream 100 bases:

>100_bases
TGCTCATCGGCGTCAGGCGTGCAGTTGATGGTTCGTACATGTTCTCTGTTGGGTTAAAATAGCTAATGGCCGTAGATTAT
TCAATAAGGCGGGAGATAAC

Downstream 100 bases:

>100_bases
GCTTTATGGACCGTCAGGAGATTTCTGTCCGTACCGCCCGGTTGAGCGATGCTGAAACCATTGCGAGGATCACTGCAGCG
TATGCTGAAAGCGGGATTAT

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MKFVDSARIVVKAGDGGNGCVSFRREKYVPKGGPDGGDGGRGGHVYLRANSQLATLLDFRYKKNYEALRGVHGQGSKKAG
KTGKDIVINVPCGTLVKNSVSGEVICDLVEDGEEFLLARGGDGGRGNPHFTTSTRQAPRYAEPGGKGEELKVDLELKLMA
DVGLVGFPNAGKSTLISVLSAARPKIADYPFTTLVPNLGIVQYGEYKSFVMADIPGIIEGAAEGKGLGIQFLRHIERTKV
LAVLVSGDGEDPVGEYRLLLGEMERFDPALLQKPRIIVVTKMDVVDEAFSLPDFEDDVPLIPVSSITRSGLEELRNALWN
TINPSIP

Sequences:

>Translated_327_residues
MKFVDSARIVVKAGDGGNGCVSFRREKYVPKGGPDGGDGGRGGHVYLRANSQLATLLDFRYKKNYEALRGVHGQGSKKAG
KTGKDIVINVPCGTLVKNSVSGEVICDLVEDGEEFLLARGGDGGRGNPHFTTSTRQAPRYAEPGGKGEELKVDLELKLMA
DVGLVGFPNAGKSTLISVLSAARPKIADYPFTTLVPNLGIVQYGEYKSFVMADIPGIIEGAAEGKGLGIQFLRHIERTKV
LAVLVSGDGEDPVGEYRLLLGEMERFDPALLQKPRIIVVTKMDVVDEAFSLPDFEDDVPLIPVSSITRSGLEELRNALWN
TINPSIP
>Mature_327_residues
MKFVDSARIVVKAGDGGNGCVSFRREKYVPKGGPDGGDGGRGGHVYLRANSQLATLLDFRYKKNYEALRGVHGQGSKKAG
KTGKDIVINVPCGTLVKNSVSGEVICDLVEDGEEFLLARGGDGGRGNPHFTTSTRQAPRYAEPGGKGEELKVDLELKLMA
DVGLVGFPNAGKSTLISVLSAARPKIADYPFTTLVPNLGIVQYGEYKSFVMADIPGIIEGAAEGKGLGIQFLRHIERTKV
LAVLVSGDGEDPVGEYRLLLGEMERFDPALLQKPRIIVVTKMDVVDEAFSLPDFEDDVPLIPVSSITRSGLEELRNALWN
TINPSIP

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=314, Percent_Identity=41.7197452229299, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI111955139, Length=355, Percent_Identity=35.4929577464789, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI111955063, Length=245, Percent_Identity=36.734693877551, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI4758796, Length=115, Percent_Identity=41.7391304347826, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI4557537, Length=73, Percent_Identity=45.2054794520548, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1789574, Length=290, Percent_Identity=53.7931034482759, Blast_Score=279, Evalue=2e-76,
Organism=Escherichia coli, GI1787454, Length=100, Percent_Identity=37, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17508313, Length=324, Percent_Identity=41.6666666666667, Blast_Score=185, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17552324, Length=306, Percent_Identity=31.6993464052288, Blast_Score=137, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI17555344, Length=115, Percent_Identity=40.8695652173913, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71981008, Length=125, Percent_Identity=35.2, Blast_Score=68, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6321962, Length=159, Percent_Identity=42.1383647798742, Blast_Score=129, Evalue=6e-31,
Organism=Saccharomyces cerevisiae, GI6319281, Length=123, Percent_Identity=36.5853658536585, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI20129375, Length=319, Percent_Identity=39.8119122257053, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24585318, Length=355, Percent_Identity=33.5211267605634, Blast_Score=153, Evalue=1e-37,
Organism=Drosophila melanogaster, GI17981711, Length=124, Percent_Identity=42.741935483871, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21356473, Length=105, Percent_Identity=42.8571428571429, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_PROA2 (B4S5P1)

Other databases:

- EMBL:   CP001108
- RefSeq:   YP_002016735.1
- ProteinModelPortal:   B4S5P1
- SMR:   B4S5P1
- GeneID:   6459995
- GenomeReviews:   CP001108_GR
- KEGG:   paa:Paes_2078
- HOGENOM:   HBG716038
- OMA:   LIDYRFN
- ProtClustDB:   PRK12299
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 35112; Mature: 35112

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFVDSARIVVKAGDGGNGCVSFRREKYVPKGGPDGGDGGRGGHVYLRANSQLATLLDFR
CCCCCCEEEEEEECCCCCCEEHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHH
YKKNYEALRGVHGQGSKKAGKTGKDIVINVPCGTLVKNSVSGEVICDLVEDGEEFLLARG
HHCCHHHHCCCCCCCCCCCCCCCCEEEEECCCCHHHHCCCCCCEEHEEHHCCCEEEEEEC
GDGGRGNPHFTTSTRQAPRYAEPGGKGEELKVDLELKLMADVGLVGFPNAGKSTLISVLS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEECCCEEECCCCCHHHHHHHHH
AARPKIADYPFTTLVPNLGIVQYGEYKSFVMADIPGIIEGAAEGKGLGIQFLRHIERTKV
HCCCCCCCCCHHHHCCCCCEEEECCCCCEEECCCCHHHHCCCCCCCCHHHHHHHHHHCEE
LAVLVSGDGEDPVGEYRLLLGEMERFDPALLQKPRIIVVTKMDVVDEAFSLPDFEDDVPL
EEEEEECCCCCCHHHHHHHHHHHHHCCHHHHCCCCEEEEEEHHHHHHHHCCCCCCCCCCE
IPVSSITRSGLEELRNALWNTINPSIP
EEHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKFVDSARIVVKAGDGGNGCVSFRREKYVPKGGPDGGDGGRGGHVYLRANSQLATLLDFR
CCCCCCEEEEEEECCCCCCEEHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHH
YKKNYEALRGVHGQGSKKAGKTGKDIVINVPCGTLVKNSVSGEVICDLVEDGEEFLLARG
HHCCHHHHCCCCCCCCCCCCCCCCEEEEECCCCHHHHCCCCCCEEHEEHHCCCEEEEEEC
GDGGRGNPHFTTSTRQAPRYAEPGGKGEELKVDLELKLMADVGLVGFPNAGKSTLISVLS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEECCCEEECCCCCHHHHHHHHH
AARPKIADYPFTTLVPNLGIVQYGEYKSFVMADIPGIIEGAAEGKGLGIQFLRHIERTKV
HCCCCCCCCCHHHHCCCCCEEEECCCCCEEECCCCHHHHCCCCCCCCHHHHHHHHHHCEE
LAVLVSGDGEDPVGEYRLLLGEMERFDPALLQKPRIIVVTKMDVVDEAFSLPDFEDDVPL
EEEEEECCCCCCHHHHHHHHHHHHHCCHHHHCCCCEEEEEEHHHHHHHHCCCCCCCCCCE
IPVSSITRSGLEELRNALWNTINPSIP
EEHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA