Click here to switch to the map view.

The map label for this gene is gmhA [H]

Identifier: 194334550

GI number: 194334550

Start: 1905460

End: 1906059

Strand: Reverse

Name: gmhA [H]

Synonym: Paes_1745

Alternate gene names: 194334550

Gene position: 1906059-1905460 (Counterclockwise)

Preceding gene: 194334551

Following gene: 194334549

Centisome position: 75.85

GC content: 36.33

Gene sequence:

>600_bases
ATGGGTATACTGGAAACAATTAAGAAGGCTATTTCTCATTCTATTGAGGTTAAACAAGATATTTTAGAAGATAAAGAGTT
GATAGGTGAAATTATAAAAGTAATAGATGATTTGATTAAAGCGCTTAATTGTGGTAATCGTATTATTTTTGCTGGTAATG
GAGGAAGTGCTGCCGATGCACAACATTTAGCTGCTGAATTTGTTAGTCGTTTTCAGTTTGATCGTCCTGGACTACCTGCC
CTATCTCTTGCTACTGATACCTCAATGATTACTGCTATTGGTAATGATTATGGTTATGAAAAATTGTTTGTTCGTCAGTT
GGAGGCACAGAGCCGTAAAGGTGACGTATTTGTAGGGCTGACAACATCAGGCAAATCACCCAATATTCTAGCAGCATTCG
ATGCTTGTAACTTATTAGGAGTAACATCAGTCGCTCTTTGTGGACTTGGAGGTGATTTGGAAGATAAAGTGGATTACTTA
ATACGAGTTCCAAGTATTCATACACCGCGTATTCAGGAAAGCCATATTTTAATAGGACATATAATTTGTGCTGAAGTAGA
ACAACAAATATTTTCTCATTTAGCACCTTCTCAGAAATGA

Upstream 100 bases:

>100_bases
GTGGTTAAGGTGTATTTGAAATCATTTTCTATAAGTGATAATGGATTTATTCGTAATGTTTTTTATGAGTTTAATTTGAT
AAAATTAAAATCGATTTGAT

Downstream 100 bases:

>100_bases
GTATTCCTTGCATTATTCTTGCTGGTGGTCTGGGTACTCGGTTACGTTCTGCTTTGCCAGATTTACCAAAATGCTTAGCC
CCTGTAGCTGGTCGTCCATT

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MGILETIKKAISHSIEVKQDILEDKELIGEIIKVIDDLIKALNCGNRIIFAGNGGSAADAQHLAAEFVSRFQFDRPGLPA
LSLATDTSMITAIGNDYGYEKLFVRQLEAQSRKGDVFVGLTTSGKSPNILAAFDACNLLGVTSVALCGLGGDLEDKVDYL
IRVPSIHTPRIQESHILIGHIICAEVEQQIFSHLAPSQK

Sequences:

>Translated_199_residues
MGILETIKKAISHSIEVKQDILEDKELIGEIIKVIDDLIKALNCGNRIIFAGNGGSAADAQHLAAEFVSRFQFDRPGLPA
LSLATDTSMITAIGNDYGYEKLFVRQLEAQSRKGDVFVGLTTSGKSPNILAAFDACNLLGVTSVALCGLGGDLEDKVDYL
IRVPSIHTPRIQESHILIGHIICAEVEQQIFSHLAPSQK
>Mature_198_residues
GILETIKKAISHSIEVKQDILEDKELIGEIIKVIDDLIKALNCGNRIIFAGNGGSAADAQHLAAEFVSRFQFDRPGLPAL
SLATDTSMITAIGNDYGYEKLFVRQLEAQSRKGDVFVGLTTSGKSPNILAAFDACNLLGVTSVALCGLGGDLEDKVDYLI
RVPSIHTPRIQESHILIGHIICAEVEQQIFSHLAPSQK

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1789539, Length=193, Percent_Identity=37.3056994818653, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1786416, Length=188, Percent_Identity=35.1063829787234, Blast_Score=121, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 21499; Mature: 21368

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGILETIKKAISHSIEVKQDILEDKELIGEIIKVIDDLIKALNCGNRIIFAGNGGSAADA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHH
QHLAAEFVSRFQFDRPGLPALSLATDTSMITAIGNDYGYEKLFVRQLEAQSRKGDVFVGL
HHHHHHHHHHHCCCCCCCCEEEHHCCCHHHHECCCCCCHHHHHHHHHHHCCCCCCEEEEE
TTSGKSPNILAAFDACNLLGVTSVALCGLGGDLEDKVDYLIRVPSIHTPRIQESHILIGH
ECCCCCCCEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHEECCCCCCCCCCCCCCHHHH
IICAEVEQQIFSHLAPSQK
HHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
GILETIKKAISHSIEVKQDILEDKELIGEIIKVIDDLIKALNCGNRIIFAGNGGSAADA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHH
QHLAAEFVSRFQFDRPGLPALSLATDTSMITAIGNDYGYEKLFVRQLEAQSRKGDVFVGL
HHHHHHHHHHHCCCCCCCCEEEHHCCCHHHHECCCCCCHHHHHHHHHHHCCCCCCEEEEE
TTSGKSPNILAAFDACNLLGVTSVALCGLGGDLEDKVDYLIRVPSIHTPRIQESHILIGH
ECCCCCCCEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHEECCCCCCCCCCCCCCHHHH
IICAEVEQQIFSHLAPSQK
HHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11279237; 12101286 [H]