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The map label for this gene is rfbC [H]

Identifier: 194334530

GI number: 194334530

Start: 1883928

End: 1884473

Strand: Reverse

Name: rfbC [H]

Synonym: Paes_1725

Alternate gene names: 194334530

Gene position: 1884473-1883928 (Counterclockwise)

Preceding gene: 194334531

Following gene: 194334529

Centisome position: 74.99

GC content: 48.53

Gene sequence:

>546_bases
ATGAATGTTATTGAAACGGCTATTCCGGATGTTCTGGTTTTTGAGCCTCGGATTTTTGGTGATGAGCGGGGGTATTTTTT
TGAGTCTTTTCGACAGGATTTTTTTGAGAAGCATGCTGGAGACGTTCATTTTGTGCAGGATAATGAGTCGCGCTCTCACT
ATGGGGTGTTGAGAGGATTACATTTTCAGAAGGCGCAGTATAGCCAGGGGAAACTGGTTCGGGTTGTCGAGGGGGCTGTG
CTTGATGTTGCTGTTGATATTCGAAAAGGGTCACCATGGTTTGGCAAGCATGTTGCGATGCATCTGAATGCAGAGAAAAA
GAACATGATGTGGATCCCGAGGGGGTTTGCTCACGGGTTTGTTGTGCTGTCGGAAACGGCGGTATTTACCTATAAGTGCG
ATAATTATTATGCGCCTGAAGCTGATGCCGGGATCCGGTGGAATGATCCGGCGCTGGGCATTGAGTGGGGTGTGGATGCT
TCGGTGATCGAGGTGTCGGAGAAGGATGCGAATTTGGCGTTACTTGCTGAGATTGGGGAATGGTAG

Upstream 100 bases:

>100_bases
TTGGCACGAATTTACACGAATTGTGGGCAAGCAGAGCTATTTTCTGTACTGGTCACTGGTCACTGGTCACTGGTCACGGA
CAACGAATCAACATAGTTCA

Downstream 100 bases:

>100_bases
CGTCTTTGGCGCAGTGACGAGTGACAAGTGACAAGTGACGAGTGACTGGTTACGAATAACGGTTAACGAATAACAGGTAA
CGAATAACGGATATTGATCC

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MNVIETAIPDVLVFEPRIFGDERGYFFESFRQDFFEKHAGDVHFVQDNESRSHYGVLRGLHFQKAQYSQGKLVRVVEGAV
LDVAVDIRKGSPWFGKHVAMHLNAEKKNMMWIPRGFAHGFVVLSETAVFTYKCDNYYAPEADAGIRWNDPALGIEWGVDA
SVIEVSEKDANLALLAEIGEW

Sequences:

>Translated_181_residues
MNVIETAIPDVLVFEPRIFGDERGYFFESFRQDFFEKHAGDVHFVQDNESRSHYGVLRGLHFQKAQYSQGKLVRVVEGAV
LDVAVDIRKGSPWFGKHVAMHLNAEKKNMMWIPRGFAHGFVVLSETAVFTYKCDNYYAPEADAGIRWNDPALGIEWGVDA
SVIEVSEKDANLALLAEIGEW
>Mature_181_residues
MNVIETAIPDVLVFEPRIFGDERGYFFESFRQDFFEKHAGDVHFVQDNESRSHYGVLRGLHFQKAQYSQGKLVRVVEGAV
LDVAVDIRKGSPWFGKHVAMHLNAEKKNMMWIPRGFAHGFVVLSETAVFTYKCDNYYAPEADAGIRWNDPALGIEWGVDA
SVIEVSEKDANLALLAEIGEW

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=179, Percent_Identity=56.9832402234637, Blast_Score=200, Evalue=6e-53,
Organism=Caenorhabditis elegans, GI17550412, Length=179, Percent_Identity=48.6033519553073, Blast_Score=147, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 20539; Mature: 20539

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVIETAIPDVLVFEPRIFGDERGYFFESFRQDFFEKHAGDVHFVQDNESRSHYGVLRGL
CCCHHHHCCCEEEECCEEECCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHCC
HFQKAQYSQGKLVRVVEGAVLDVAVDIRKGSPWFGKHVAMHLNAEKKNMMWIPRGFAHGF
CCCCCCCCCCCEEEEECCEEEEEEEEEECCCCCCCCEEEEEECCCCCCEEEEECCCCCEE
VVLSETAVFTYKCDNYYAPEADAGIRWNDPALGIEWGVDASVIEVSEKDANLALLAEIGE
EEEECCEEEEEECCCEECCCCCCCEEECCCCCEEEECCCCEEEEEECCCCCEEEEEECCC
W
C
>Mature Secondary Structure
MNVIETAIPDVLVFEPRIFGDERGYFFESFRQDFFEKHAGDVHFVQDNESRSHYGVLRGL
CCCHHHHCCCEEEECCEEECCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHCC
HFQKAQYSQGKLVRVVEGAVLDVAVDIRKGSPWFGKHVAMHLNAEKKNMMWIPRGFAHGF
CCCCCCCCCCCEEEEECCEEEEEEEEEECCCCCCCCEEEEEECCCCCCEEEEECCCCCEE
VVLSETAVFTYKCDNYYAPEADAGIRWNDPALGIEWGVDASVIEVSEKDANLALLAEIGE
EEEECCEEEEEECCCEECCCCCCCEEECCCCCEEEECCCCEEEEEECCCCCEEEEEECCC
W
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1710759; 11677609; 10802738 [H]