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The map label for this gene is 194334484

Identifier: 194334484

GI number: 194334484

Start: 1830457

End: 1831761

Strand: Reverse

Name: 194334484

Synonym: Paes_1679

Alternate gene names: NA

Gene position: 1831761-1830457 (Counterclockwise)

Preceding gene: 194334485

Following gene: 194334483

Centisome position: 72.89

GC content: 46.82

Gene sequence:

>1305_bases
ATGCTGTCTCGTGACCTTGAAGAAGGTGGCAAGTCGAAGCCAAGGGTGATCATTTATTCCGGTAAAGGCGGAACCGGCAA
AACGACAATTTCATCGTCAACCGCTGTTGCCCTGGCAAGACAGAATAAACGGGTTCTGATCATGTCTTCAGACCCTGCTC
ATTCCCTTTCGGATGTGTTTGATACGCAGATCGGAAGAAATGAGCCTCAGCAGATTGAAAAAAACCTCTATGGACTTGAG
GTCGATACGATCTATGAGCTGAAGAAGAATATGTCGGGTTTTCAGAAATTCGTTTCTTCTTCATATAAGAACCAGGGGAT
AGACAGCGGCATGGCTTCCGAACTGACAACCCAGCCGGGTCTGGATGAGATTTTTGCCTTGAGCAGGCTGGTTGATGAAG
CTAATTCCGGTAAATGGGATGCTGTCGTGCTCGATACTTCGCCGACAGGCAATACACTTCGCCTGCTTGCCTATCCGGAA
ATTATCATTGGCGGCAATATGGGCAAACAGTTTTTCAAGCTCTACAAGAGCATGTCTTCACTTGCCCGGCCAATGAGTAA
GAATTCCATCCCTGACGAAGAGTTTTTCAATGAGGTCAACGTTCTGTTGAAGCAGATGGAGGATATCAATCAGTTTATTC
TGAGCCCCGAGGTGACCTTCCGGCTTGTGTTGAACCCTGAAAAACTTTCTATTCTCGAGACGAAGCGGGCCTATACCTTC
GTGCATCTCTACGGAATTAATATTGACGGTATTGTTATCAACAAGATTTTGCCGACGTCGAAGACCGTTGGAGAGTATTT
CGAATTCTGGGCTGATTTGCACAGCAAGTATCTTATGGAGATTGACAACTCCTTTTATCCGACCCCTGTCTTTCGATGCC
AGCTCCAGCGTACCGAGCCTATCGGTCCCGATGCCCTGTATGACGTCAGTCAGCTGGTGTTTGGTGAGACGCTTCCCGAC
AAGATTTTTTATTCGGGCAAGAATTTCTGGATCGAGAGTAAAAAAGGGACCCAGTCAGGAGAGCATCGTGAGATTCTTTG
TATCCGGATCCCGTTCCTTAAGGAGGTTGAGGATGTGGCGATCGAACGGATGGGAACCGATATCGTCGTTACTATCGACA
GAGCACAGCGTATTATCACTCTGCCAAGGGCTCTCTACAGTCTTGAAATGGAGAGTTATGTCAGGGAGGATGATGTATTG
AAATTGATTTTCAAGGAGATTCCCGTTGAGAAAGAGGAGATGGAATTGAACGTTAACAAGAACGTGCTGAATAAATTGCG
CTCCCTGAGGAAAATGAGGCTCTGA

Upstream 100 bases:

>100_bases
GGAAAAATGGTACTTTTTATGCTTTACAGCCGGCGCGGCTGATTCTGTTAGGAGTGATGCGGCGGTTTATGTGATGTGAT
ACAAAAAGGAGAGATTTTTT

Downstream 100 bases:

>100_bases
GCGGCTTTTTCTCCGGTTTCGTTGTGGTTTTGGCAGTATTCTTTGTATTTTCTCTACTTGAAATGTTAAATTGGTAGGAA
TTTTCACTCCACATAATTCT

Product: arsenite-activated ATPase ArsA

Products: NA

Alternate protein names: Arsenical resistance ATPase; Arsenite-translocating ATPase; Arsenite-transporting ATPase [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MLSRDLEEGGKSKPRVIIYSGKGGTGKTTISSSTAVALARQNKRVLIMSSDPAHSLSDVFDTQIGRNEPQQIEKNLYGLE
VDTIYELKKNMSGFQKFVSSSYKNQGIDSGMASELTTQPGLDEIFALSRLVDEANSGKWDAVVLDTSPTGNTLRLLAYPE
IIIGGNMGKQFFKLYKSMSSLARPMSKNSIPDEEFFNEVNVLLKQMEDINQFILSPEVTFRLVLNPEKLSILETKRAYTF
VHLYGINIDGIVINKILPTSKTVGEYFEFWADLHSKYLMEIDNSFYPTPVFRCQLQRTEPIGPDALYDVSQLVFGETLPD
KIFYSGKNFWIESKKGTQSGEHREILCIRIPFLKEVEDVAIERMGTDIVVTIDRAQRIITLPRALYSLEMESYVREDDVL
KLIFKEIPVEKEEMELNVNKNVLNKLRSLRKMRL

Sequences:

>Translated_434_residues
MLSRDLEEGGKSKPRVIIYSGKGGTGKTTISSSTAVALARQNKRVLIMSSDPAHSLSDVFDTQIGRNEPQQIEKNLYGLE
VDTIYELKKNMSGFQKFVSSSYKNQGIDSGMASELTTQPGLDEIFALSRLVDEANSGKWDAVVLDTSPTGNTLRLLAYPE
IIIGGNMGKQFFKLYKSMSSLARPMSKNSIPDEEFFNEVNVLLKQMEDINQFILSPEVTFRLVLNPEKLSILETKRAYTF
VHLYGINIDGIVINKILPTSKTVGEYFEFWADLHSKYLMEIDNSFYPTPVFRCQLQRTEPIGPDALYDVSQLVFGETLPD
KIFYSGKNFWIESKKGTQSGEHREILCIRIPFLKEVEDVAIERMGTDIVVTIDRAQRIITLPRALYSLEMESYVREDDVL
KLIFKEIPVEKEEMELNVNKNVLNKLRSLRKMRL
>Mature_434_residues
MLSRDLEEGGKSKPRVIIYSGKGGTGKTTISSSTAVALARQNKRVLIMSSDPAHSLSDVFDTQIGRNEPQQIEKNLYGLE
VDTIYELKKNMSGFQKFVSSSYKNQGIDSGMASELTTQPGLDEIFALSRLVDEANSGKWDAVVLDTSPTGNTLRLLAYPE
IIIGGNMGKQFFKLYKSMSSLARPMSKNSIPDEEFFNEVNVLLKQMEDINQFILSPEVTFRLVLNPEKLSILETKRAYTF
VHLYGINIDGIVINKILPTSKTVGEYFEFWADLHSKYLMEIDNSFYPTPVFRCQLQRTEPIGPDALYDVSQLVFGETLPD
KIFYSGKNFWIESKKGTQSGEHREILCIRIPFLKEVEDVAIERMGTDIVVTIDRAQRIITLPRALYSLEMESYVREDDVL
KLIFKEIPVEKEEMELNVNKNVLNKLRSLRKMRL

Specific function: Anion-transporting ATPase. Catalyzes the extrusion of arsenite [H]

COG id: COG0003

COG function: function code P; Oxyanion-translocating ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arsA ATPase family [H]

Homologues:

Organism=Homo sapiens, GI50428938, Length=295, Percent_Identity=25.0847457627119, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17557003, Length=306, Percent_Identity=26.797385620915, Blast_Score=96, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6320103, Length=314, Percent_Identity=26.4331210191083, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24586297, Length=294, Percent_Identity=25.8503401360544, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003348 [H]

Pfam domain/function: NA

EC number: =3.6.3.16 [H]

Molecular weight: Translated: 49334; Mature: 49334

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSRDLEEGGKSKPRVIIYSGKGGTGKTTISSSTAVALARQNKRVLIMSSDPAHSLSDVF
CCCCCHHHCCCCCCEEEEEECCCCCCCEEECCCCEEEEEECCCEEEEEECCCCHHHHHHH
DTQIGRNEPQQIEKNLYGLEVDTIYELKKNMSGFQKFVSSSYKNQGIDSGMASELTTQPG
HHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCC
LDEIFALSRLVDEANSGKWDAVVLDTSPTGNTLRLLAYPEIIIGGNMGKQFFKLYKSMSS
HHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEECCCEEEECCCCHHHHHHHHHHHH
LARPMSKNSIPDEEFFNEVNVLLKQMEDINQFILSPEVTFRLVLNPEKLSILETKRAYTF
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHEECCCEEEE
VHLYGINIDGIVINKILPTSKTVGEYFEFWADLHSKYLMEIDNSFYPTPVFRCQLQRTEP
EEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCC
IGPDALYDVSQLVFGETLPDKIFYSGKNFWIESKKGTQSGEHREILCIRIPFLKEVEDVA
CCCHHHHHHHHHHHCCCCCHHHEECCCCEEEECCCCCCCCCCCEEEEEECCHHHHHHHHH
IERMGTDIVVTIDRAQRIITLPRALYSLEMESYVREDDVLKLIFKEIPVEKEEMELNVNK
HHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHEECCCH
NVLNKLRSLRKMRL
HHHHHHHHHHHHCC
>Mature Secondary Structure
MLSRDLEEGGKSKPRVIIYSGKGGTGKTTISSSTAVALARQNKRVLIMSSDPAHSLSDVF
CCCCCHHHCCCCCCEEEEEECCCCCCCEEECCCCEEEEEECCCEEEEEECCCCHHHHHHH
DTQIGRNEPQQIEKNLYGLEVDTIYELKKNMSGFQKFVSSSYKNQGIDSGMASELTTQPG
HHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCC
LDEIFALSRLVDEANSGKWDAVVLDTSPTGNTLRLLAYPEIIIGGNMGKQFFKLYKSMSS
HHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEECCCEEEECCCCHHHHHHHHHHHH
LARPMSKNSIPDEEFFNEVNVLLKQMEDINQFILSPEVTFRLVLNPEKLSILETKRAYTF
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHEECCCEEEE
VHLYGINIDGIVINKILPTSKTVGEYFEFWADLHSKYLMEIDNSFYPTPVFRCQLQRTEP
EEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCC
IGPDALYDVSQLVFGETLPDKIFYSGKNFWIESKKGTQSGEHREILCIRIPFLKEVEDVA
CCCHHHHHHHHHHHCCCCCHHHEECCCCEEEECCCCCCCCCCCEEEEEECCHHHHHHHHH
IERMGTDIVVTIDRAQRIITLPRALYSLEMESYVREDDVLKLIFKEIPVEKEEMELNVNK
HHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHEECCCH
NVLNKLRSLRKMRL
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]