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The map label for this gene is fabI1 [H]

Identifier: 194334483

GI number: 194334483

Start: 1829455

End: 1830354

Strand: Reverse

Name: fabI1 [H]

Synonym: Paes_1678

Alternate gene names: 194334483

Gene position: 1830354-1829455 (Counterclockwise)

Preceding gene: 194334484

Following gene: 194334482

Centisome position: 72.84

GC content: 46.22

Gene sequence:

>900_bases
ATGGAATCAGCTTATATCATGCCTGATAAAGCGCATTACGGTCTTTTGAAAGGAAAGAAGGGGATAATATTCGGTCCTCT
GGATGAAAGCAGTATTGGTTGGCAGATTGCTCTTCATGCCTATAATGAGGGTGCCGAGATTGCTATTTCAAATGTAGCTA
CAGCATTGAGGTTCGGAAATATAGACGCACTTTCCAAAGCATGCGGTAACGCTCCTCTTATCGTATGCGACGCCTCCAGG
GACGAGGATGTCAATAAGGCATTCCTGGAGTTGAAAGAGCAGATCGGTTCTGTTGATTTTATCGTTCATTCGATCGGTAT
GTCTCAAAACATCCGTAAGCAGATGCCTTACGAGGAACTGAACTACGAATGGTTTATGAGGACTCTCGATGTTTCAGGGA
TCTCCCTGCACAGAATCGTTTCCTCTGCATTGAAAAACGATGCGCTCAATGATGGGGCAAGCGTTCTTGCTCTTTCGTAT
ATTGCTTCTCAGAGAAACTACTGGACCTATTCTGATATGGGGGATGCGAAATCTCTTCTTGAGTCGATCGTTCGAAGTTA
TGGGCCTCGACTTGCCAAAAGAGGAATACGCATCAATACCATTTCTCAGAGTCCGACCTATACCAAAGCTGGAAGCGGTA
TTCCCGGCTTTGAGCAGATGCATGAATACAGTGATTTGATGTCACCTCTCGGCAACGCTTCTGCTGAAGAGTGTGCTGAA
TATTCGGTGACGCTCCTGAGCGATCTCACCAGGAAGGTGACCATGCAAAATCTTTTCCACGACGGCGGTTATAGTTCCAT
GGGCGCAACGATACCCATGATCAGGCTTGCTCATGAAGTTCTTCATGACAATGACCTTGCCGAACGGGTCAGTCTCGACG
ATTATAAACCCTCCAGATAA

Upstream 100 bases:

>100_bases
GGCTTTTTCTCCGGTTTCGTTGTGGTTTTGGCAGTATTCTTTGTATTTTCTCTACTTGAAATGTTAAATTGGTAGGAATT
TTCACTCCACATAATTCTTA

Downstream 100 bases:

>100_bases
TAACGACGGGGGAGGGCAACTCCTCTTCCCCGGATAGTGTGGCGTATCCGGTCAGGGATCGTCATTCATTATACTGTTAT
ATTTTATTGTTTGATGAAGT

Product: enoyl-(acyl-carrier-protein) reductase (NADH)

Products: NA

Alternate protein names: NADH-dependent enoyl-ACP reductase 1 [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MESAYIMPDKAHYGLLKGKKGIIFGPLDESSIGWQIALHAYNEGAEIAISNVATALRFGNIDALSKACGNAPLIVCDASR
DEDVNKAFLELKEQIGSVDFIVHSIGMSQNIRKQMPYEELNYEWFMRTLDVSGISLHRIVSSALKNDALNDGASVLALSY
IASQRNYWTYSDMGDAKSLLESIVRSYGPRLAKRGIRINTISQSPTYTKAGSGIPGFEQMHEYSDLMSPLGNASAEECAE
YSVTLLSDLTRKVTMQNLFHDGGYSSMGATIPMIRLAHEVLHDNDLAERVSLDDYKPSR

Sequences:

>Translated_299_residues
MESAYIMPDKAHYGLLKGKKGIIFGPLDESSIGWQIALHAYNEGAEIAISNVATALRFGNIDALSKACGNAPLIVCDASR
DEDVNKAFLELKEQIGSVDFIVHSIGMSQNIRKQMPYEELNYEWFMRTLDVSGISLHRIVSSALKNDALNDGASVLALSY
IASQRNYWTYSDMGDAKSLLESIVRSYGPRLAKRGIRINTISQSPTYTKAGSGIPGFEQMHEYSDLMSPLGNASAEECAE
YSVTLLSDLTRKVTMQNLFHDGGYSSMGATIPMIRLAHEVLHDNDLAERVSLDDYKPSR
>Mature_299_residues
MESAYIMPDKAHYGLLKGKKGIIFGPLDESSIGWQIALHAYNEGAEIAISNVATALRFGNIDALSKACGNAPLIVCDASR
DEDVNKAFLELKEQIGSVDFIVHSIGMSQNIRKQMPYEELNYEWFMRTLDVSGISLHRIVSSALKNDALNDGASVLALSY
IASQRNYWTYSDMGDAKSLLESIVRSYGPRLAKRGIRINTISQSPTYTKAGSGIPGFEQMHEYSDLMSPLGNASAEECAE
YSVTLLSDLTRKVTMQNLFHDGGYSSMGATIPMIRLAHEVLHDNDLAERVSLDDYKPSR

Specific function: Fatty acid biosynthesis pathway; second reduction step. [C]

COG id: COG0623

COG function: function code I; Enoyl-[acyl-carrier-protein] reductase (NADH)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787545, Length=254, Percent_Identity=29.5275590551181, Blast_Score=109, Evalue=2e-25,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR014358
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.3.1.9 [H]

Molecular weight: Translated: 32972; Mature: 32972

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESAYIMPDKAHYGLLKGKKGIIFGPLDESSIGWQIALHAYNEGAEIAISNVATALRFGN
CCCCCCCCCCCHHHHHCCCCCCEECCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCC
IDALSKACGNAPLIVCDASRDEDVNKAFLELKEQIGSVDFIVHSIGMSQNIRKQMPYEEL
HHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHCCHHHH
NYEWFMRTLDVSGISLHRIVSSALKNDALNDGASVLALSYIASQRNYWTYSDMGDAKSLL
CHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEECCCCCHHHHHH
ESIVRSYGPRLAKRGIRINTISQSPTYTKAGSGIPGFEQMHEYSDLMSPLGNASAEECAE
HHHHHHHCHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHH
YSVTLLSDLTRKVTMQNLFHDGGYSSMGATIPMIRLAHEVLHDNDLAERVSLDDYKPSR
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCCCCCC
>Mature Secondary Structure
MESAYIMPDKAHYGLLKGKKGIIFGPLDESSIGWQIALHAYNEGAEIAISNVATALRFGN
CCCCCCCCCCCHHHHHCCCCCCEECCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCC
IDALSKACGNAPLIVCDASRDEDVNKAFLELKEQIGSVDFIVHSIGMSQNIRKQMPYEEL
HHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHCCHHHH
NYEWFMRTLDVSGISLHRIVSSALKNDALNDGASVLALSYIASQRNYWTYSDMGDAKSLL
CHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEECCCCCHHHHHH
ESIVRSYGPRLAKRGIRINTISQSPTYTKAGSGIPGFEQMHEYSDLMSPLGNASAEECAE
HHHHHHHCHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHH
YSVTLLSDLTRKVTMQNLFHDGGYSSMGATIPMIRLAHEVLHDNDLAERVSLDDYKPSR
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]