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The map label for this gene is hupE [H]

Identifier: 194334445

GI number: 194334445

Start: 1784885

End: 1785922

Strand: Reverse

Name: hupE [H]

Synonym: Paes_1640

Alternate gene names: 194334445

Gene position: 1785922-1784885 (Counterclockwise)

Preceding gene: 194334446

Following gene: 194334444

Centisome position: 71.07

GC content: 53.66

Gene sequence:

>1038_bases
ATGCAGTTTGAATGTCCTTTGCCTCAAGCGGATCATGATCGTGTTCAGATCGCTCATGGCGCTGGCGGGAGATTGTCGAG
AGAGCTGATGGCAACGGTGTTCATGCCTGCTCTGAACAATCCGATGCTTGCCGAACTTGATGATCAGGCGCGATTGATCC
TGCCGCCTGGAAGGGTCGCTTTTACCACCGATACCTATGTCATAACACCCCTGTTTTTCCCCGGGGGAAATATCGGCGAA
CTGGCTGTTCACGGTACGGTGAATGACCTGGCTGTCGGCGGGGCGGTTCCCAGATTTCTGAGTGCCGGATTTGTTCTTGA
GGAGGGGTTTCCTCTTGCGGATTTGCAGCTGATTGTCAGCAGTCTTGGTCAGGCTGCAGCCAAGGCCGGTGTTTCAGTCG
TTACGGGTGATACAAAAGTTGTTCAGAAAGGACAGTGCGACGGGGTTTTTATCAACACATCAGGTATTGGCGAGATTCGT
GAAGGTATTGACGTTTCATGTCGTCATCTTCAACCCGGAGACCGGCTGATTCTGTCGGGCACTCTCGCCGATCATGGCAT
TGCGGTTCTCTGCGCGCGTGAGGGATTGTCGATGCAGATGTCGGTAGAGAGTGACTCGGCATCGTTGAATGCAATGATAT
CGGCAGTTCTGGAGGTCTTTCCCGGCATCCACGCGATGCGCGATCCTACGAGAGGCGGTGCGGCGGCGACGCTTAATGAA
CTGGCTTCAGCTTCAGGTGTAGGGATTGTCCTGGAAGAAGAGGCGATACCGGTACATCCTGAAGTTCGTGGAGCCTGTGA
ATTGCTTGGTATTGATCCGCTGACTGTCGCAAACGAGGGAAAGGTCATTATTGCGGTTCCTTCAAATGGTGCCGATGCAG
TCCTTGATGCCTTGCGCCGTGATGTTCATGGAAAAAATGCCGCGGTGATCGGAGAGGCTGTCGGCGATCATCCCGGGGTG
GTCGTCATGCGGACTGCATATGGCAGCAGAAGAGTTGTTGAAATGCCTCTTGGAGAACAACTTCCCCGTATATGCTGA

Upstream 100 bases:

>100_bases
TGGTGCCCCGATGGTATCGGGAGAGGGCGCTTGTGCGGCATACTATCGATATCAGCGGGCCTGGGGAGCCTGATTATTCA
ACATTTACCACGCACCAATT

Downstream 100 bases:

>100_bases
TCGATACGGATATCGTTGTTGTCTGGGGTTCCGATAGCGTCAGGGCTTATTGAGACGTGTGCCTTGCTGTTTATTTGGAA
TAAGCGTAAATTACGGTTAC

Product: hydrogenase expression/formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MQFECPLPQADHDRVQIAHGAGGRLSRELMATVFMPALNNPMLAELDDQARLILPPGRVAFTTDTYVITPLFFPGGNIGE
LAVHGTVNDLAVGGAVPRFLSAGFVLEEGFPLADLQLIVSSLGQAAAKAGVSVVTGDTKVVQKGQCDGVFINTSGIGEIR
EGIDVSCRHLQPGDRLILSGTLADHGIAVLCAREGLSMQMSVESDSASLNAMISAVLEVFPGIHAMRDPTRGGAAATLNE
LASASGVGIVLEEEAIPVHPEVRGACELLGIDPLTVANEGKVIIAVPSNGADAVLDALRRDVHGKNAAVIGEAVGDHPGV
VVMRTAYGSRRVVEMPLGEQLPRIC

Sequences:

>Translated_345_residues
MQFECPLPQADHDRVQIAHGAGGRLSRELMATVFMPALNNPMLAELDDQARLILPPGRVAFTTDTYVITPLFFPGGNIGE
LAVHGTVNDLAVGGAVPRFLSAGFVLEEGFPLADLQLIVSSLGQAAAKAGVSVVTGDTKVVQKGQCDGVFINTSGIGEIR
EGIDVSCRHLQPGDRLILSGTLADHGIAVLCAREGLSMQMSVESDSASLNAMISAVLEVFPGIHAMRDPTRGGAAATLNE
LASASGVGIVLEEEAIPVHPEVRGACELLGIDPLTVANEGKVIIAVPSNGADAVLDALRRDVHGKNAAVIGEAVGDHPGV
VVMRTAYGSRRVVEMPLGEQLPRIC
>Mature_345_residues
MQFECPLPQADHDRVQIAHGAGGRLSRELMATVFMPALNNPMLAELDDQARLILPPGRVAFTTDTYVITPLFFPGGNIGE
LAVHGTVNDLAVGGAVPRFLSAGFVLEEGFPLADLQLIVSSLGQAAAKAGVSVVTGDTKVVQKGQCDGVFINTSGIGEIR
EGIDVSCRHLQPGDRLILSGTLADHGIAVLCAREGLSMQMSVESDSASLNAMISAVLEVFPGIHAMRDPTRGGAAATLNE
LASASGVGIVLEEEAIPVHPEVRGACELLGIDPLTVANEGKVIIAVPSNGADAVLDALRRDVHGKNAAVIGEAVGDHPGV
VVMRTAYGSRRVVEMPLGEQLPRIC

Specific function: May be involved in the maturation of the nifE hydrogenase [H]

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=338, Percent_Identity=50.5917159763314, Blast_Score=324, Evalue=5e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 35924; Mature: 35924

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFECPLPQADHDRVQIAHGAGGRLSRELMATVFMPALNNPMLAELDDQARLILPPGRVA
CCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEECCCCEEEECCCCEE
FTTDTYVITPLFFPGGNIGELAVHGTVNDLAVGGAVPRFLSAGFVLEEGFPLADLQLIVS
EEECCEEEEEEEECCCCCCCEEEECCHHHHHHCCCHHHHHHCCEEEECCCCHHHHHHHHH
SLGQAAAKAGVSVVTGDTKVVQKGQCDGVFINTSGIGEIREGIDVSCRHLQPGDRLILSG
HHHHHHHHCCCEEEECCHHEEECCCCCEEEEECCCCHHHHCCCCCEEEECCCCCEEEEEE
TLADHGIAVLCAREGLSMQMSVESDSASLNAMISAVLEVFPGIHAMRDPTRGGAAATLNE
CCCCCCEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHH
LASASGVGIVLEEEAIPVHPEVRGACELLGIDPLTVANEGKVIIAVPSNGADAVLDALRR
HHCCCCCEEEEECCCCCCCCCCCCCEEEECCCCEEEECCCEEEEEECCCCHHHHHHHHHH
DVHGKNAAVIGEAVGDHPGVVVMRTAYGSRRVVEMPLGEQLPRIC
HCCCCCEEEEEHHHCCCCCEEEEEECCCCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MQFECPLPQADHDRVQIAHGAGGRLSRELMATVFMPALNNPMLAELDDQARLILPPGRVA
CCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEECCCCEEEECCCCEE
FTTDTYVITPLFFPGGNIGELAVHGTVNDLAVGGAVPRFLSAGFVLEEGFPLADLQLIVS
EEECCEEEEEEEECCCCCCCEEEECCHHHHHHCCCHHHHHHCCEEEECCCCHHHHHHHHH
SLGQAAAKAGVSVVTGDTKVVQKGQCDGVFINTSGIGEIREGIDVSCRHLQPGDRLILSG
HHHHHHHHCCCEEEECCHHEEECCCCCEEEEECCCCHHHHCCCCCEEEECCCCCEEEEEE
TLADHGIAVLCAREGLSMQMSVESDSASLNAMISAVLEVFPGIHAMRDPTRGGAAATLNE
CCCCCCEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHH
LASASGVGIVLEEEAIPVHPEVRGACELLGIDPLTVANEGKVIIAVPSNGADAVLDALRR
HHCCCCCEEEEECCCCCCCCCCCCCEEEECCCCEEEECCCEEEEEECCCCHHHHHHHHHH
DVHGKNAAVIGEAVGDHPGVVVMRTAYGSRRVVEMPLGEQLPRIC
HCCCCCEEEEEHHHCCCCCEEEEEECCCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1526470 [H]