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The map label for this gene is ybdL [H]

Identifier: 194334309

GI number: 194334309

Start: 1643718

End: 1644884

Strand: Reverse

Name: ybdL [H]

Synonym: Paes_1502

Alternate gene names: 194334309

Gene position: 1644884-1643718 (Counterclockwise)

Preceding gene: 194334310

Following gene: 194334306

Centisome position: 65.46

GC content: 52.44

Gene sequence:

>1167_bases
ATGGCGCTTGGAACCAGTGAACGATGCCGTTCGGTTCTTCAGTCGGATATCCGGATGATGTCGGTCGAATGCCATCGTCT
TGGCGGAATCAATCTTTCACAGGGAGTGTGCGATACCCCTGTACCCGGAGTTGTCCTTGAGGGCGCCAGTCATGCATTGA
GCCAAAGACAGAACAGCTATACCCATTATGCCGGTATAGGGGGGCTTCGGGAGGCTCTTGCGGAAAAATACCGGACGATG
TATGGTATCGACGTAGACCCGCAACAGGAAATTGTTGTCAGTGCGGGTGCCACCGGCGCAATGTATTGCGCTTTTCAGGC
ACTGCTGAATCCCGGCGATGAGGTGATCGTTTTCGAGCCCTATTACGGTTATCATATCAGTACCCTTAACGCTCTTCAGG
CAGTTCCTGTGTTTCTTTCGCTCACATCACCGGACTGGACTTTCAGTGAAGCTGATCTGGAGGCAGCGGTGAGTTCCCGA
ACCAGAGCCATACTTATCAATACGCCCGGCAACCCGTCAGGAAAAGTGTTTACTCTCGCTGAACTGCAGCGTATAGCCGA
TTTTGCTGAGGAGCACGATCTTTTTGTGTTTACCGATGAAATCTATGAGCATTTTCTCTATGACGGGCGAAGGCACCATT
CCCCGTTCGCTCTTCCCGGAATGCGGAAGCGAACGGTGCTCATTTCAGGCTTTTCCAAAACGTTCAGCGTGACCGGATGG
CGGATAGGTTATGCAATTTCTGATGCACGATGGGCTCAGGCGATCGGATATTTTAATGACCTGGTTTACGTATGCGCACC
TTCGGCGCTTCAGCCGGGCGTTGCGGCAGGTCTTGCCACCCTCGATACATCTTATTACCTGTCGTTATCGGCAGAGTACG
GGTTCAAGCGCAACCGTTTCTGTCGGGCTCTTGGTGAGGCAGGCCTGAATGCTGTTCTTCCGCAGGGAGCTTACTACGTT
TTAGCTGATGTTTCGCATCTTCCGGGAAGCACAACCCGCGACAAGGCAATGCATATTCTTCGGACGACAGGTGTCGCCTC
TGTGCCCGGCAGCGCGTTTTTTCGCAATGAAAATGATCAGCACCTGGTCAGGTTCTGTTACGCCAAAGATGATGTTGTGC
TTGATGCGGCCTGTGAGCGCCTGATGAAGCTGAAGGAGATGGATTAA

Upstream 100 bases:

>100_bases
GTGTTTGCTATGATCGGCGTCTTTATTGCTGCCAGGTTTTTCTGATGGCTTTTTCCGGATCCGGAAGGGGCAATAAACAG
TGAGGTAAGGAGATAGGACT

Downstream 100 bases:

>100_bases
AAAAGCCGATACCGCAGATGTAAGCCGAATTCTGTTCTCTCTTCCGGTCGTGACCGGAGGAGAGTTGCAGTCATTTATCT
GATGCGGCTCACCCGGCAAC

Product: aminotransferase class I and II protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MALGTSERCRSVLQSDIRMMSVECHRLGGINLSQGVCDTPVPGVVLEGASHALSQRQNSYTHYAGIGGLREALAEKYRTM
YGIDVDPQQEIVVSAGATGAMYCAFQALLNPGDEVIVFEPYYGYHISTLNALQAVPVFLSLTSPDWTFSEADLEAAVSSR
TRAILINTPGNPSGKVFTLAELQRIADFAEEHDLFVFTDEIYEHFLYDGRRHHSPFALPGMRKRTVLISGFSKTFSVTGW
RIGYAISDARWAQAIGYFNDLVYVCAPSALQPGVAAGLATLDTSYYLSLSAEYGFKRNRFCRALGEAGLNAVLPQGAYYV
LADVSHLPGSTTRDKAMHILRTTGVASVPGSAFFRNENDQHLVRFCYAKDDVVLDAACERLMKLKEMD

Sequences:

>Translated_388_residues
MALGTSERCRSVLQSDIRMMSVECHRLGGINLSQGVCDTPVPGVVLEGASHALSQRQNSYTHYAGIGGLREALAEKYRTM
YGIDVDPQQEIVVSAGATGAMYCAFQALLNPGDEVIVFEPYYGYHISTLNALQAVPVFLSLTSPDWTFSEADLEAAVSSR
TRAILINTPGNPSGKVFTLAELQRIADFAEEHDLFVFTDEIYEHFLYDGRRHHSPFALPGMRKRTVLISGFSKTFSVTGW
RIGYAISDARWAQAIGYFNDLVYVCAPSALQPGVAAGLATLDTSYYLSLSAEYGFKRNRFCRALGEAGLNAVLPQGAYYV
LADVSHLPGSTTRDKAMHILRTTGVASVPGSAFFRNENDQHLVRFCYAKDDVVLDAACERLMKLKEMD
>Mature_387_residues
ALGTSERCRSVLQSDIRMMSVECHRLGGINLSQGVCDTPVPGVVLEGASHALSQRQNSYTHYAGIGGLREALAEKYRTMY
GIDVDPQQEIVVSAGATGAMYCAFQALLNPGDEVIVFEPYYGYHISTLNALQAVPVFLSLTSPDWTFSEADLEAAVSSRT
RAILINTPGNPSGKVFTLAELQRIADFAEEHDLFVFTDEIYEHFLYDGRRHHSPFALPGMRKRTVLISGFSKTFSVTGWR
IGYAISDARWAQAIGYFNDLVYVCAPSALQPGVAAGLATLDTSYYLSLSAEYGFKRNRFCRALGEAGLNAVLPQGAYYVL
ADVSHLPGSTTRDKAMHILRTTGVASVPGSAFFRNENDQHLVRFCYAKDDVVLDAACERLMKLKEMD

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=389, Percent_Identity=32.133676092545, Blast_Score=221, Evalue=8e-58,
Organism=Homo sapiens, GI169881279, Length=389, Percent_Identity=32.133676092545, Blast_Score=221, Evalue=8e-58,
Organism=Homo sapiens, GI56713254, Length=380, Percent_Identity=34.7368421052632, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI56713256, Length=380, Percent_Identity=34.7368421052632, Blast_Score=217, Evalue=1e-56,
Organism=Homo sapiens, GI169881281, Length=302, Percent_Identity=30.4635761589404, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI4507369, Length=366, Percent_Identity=21.3114754098361, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI4885351, Length=350, Percent_Identity=26.8571428571429, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1786816, Length=365, Percent_Identity=33.1506849315069, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1788627, Length=308, Percent_Identity=30.1948051948052, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1788722, Length=345, Percent_Identity=26.3768115942029, Blast_Score=109, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71994476, Length=391, Percent_Identity=32.2250639386189, Blast_Score=200, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI71994472, Length=391, Percent_Identity=32.2250639386189, Blast_Score=200, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI17567369, Length=394, Percent_Identity=29.9492385786802, Blast_Score=174, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI17567663, Length=304, Percent_Identity=25, Blast_Score=105, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6322401, Length=387, Percent_Identity=29.4573643410853, Blast_Score=171, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6323118, Length=354, Percent_Identity=23.4463276836158, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28573069, Length=393, Percent_Identity=34.8600508905852, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI24646114, Length=393, Percent_Identity=34.8600508905852, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI28573067, Length=393, Percent_Identity=34.8600508905852, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI28573065, Length=393, Percent_Identity=34.8600508905852, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI18859735, Length=356, Percent_Identity=26.685393258427, Blast_Score=99, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 42605; Mature: 42474

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00024 HEMOPEXIN ; PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALGTSERCRSVLQSDIRMMSVECHRLGGINLSQGVCDTPVPGVVLEGASHALSQRQNSY
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHCCC
THYAGIGGLREALAEKYRTMYGIDVDPQQEIVVSAGATGAMYCAFQALLNPGDEVIVFEP
CHHHCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCEEEECC
YYGYHISTLNALQAVPVFLSLTSPDWTFSEADLEAAVSSRTRAILINTPGNPSGKVFTLA
CCCEEEHHHHHHHHCEEEEEECCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCEEEHH
ELQRIADFAEEHDLFVFTDEIYEHFLYDGRRHHSPFALPGMRKRTVLISGFSKTFSVTGW
HHHHHHHHHHHCCEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCE
RIGYAISDARWAQAIGYFNDLVYVCAPSALQPGVAAGLATLDTSYYLSLSAEYGFKRNRF
EEEEEECCHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHCCCEEEEEEECCCCCCHHHH
CRALGEAGLNAVLPQGAYYVLADVSHLPGSTTRDKAMHILRTTGVASVPGSAFFRNENDQ
HHHHHHCCCCEECCCCCEEEEEEHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHCCCCCHH
HLVRFCYAKDDVVLDAACERLMKLKEMD
HEEEEECCCCCEEHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ALGTSERCRSVLQSDIRMMSVECHRLGGINLSQGVCDTPVPGVVLEGASHALSQRQNSY
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHCCC
THYAGIGGLREALAEKYRTMYGIDVDPQQEIVVSAGATGAMYCAFQALLNPGDEVIVFEP
CHHHCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCEEEECC
YYGYHISTLNALQAVPVFLSLTSPDWTFSEADLEAAVSSRTRAILINTPGNPSGKVFTLA
CCCEEEHHHHHHHHCEEEEEECCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCEEEHH
ELQRIADFAEEHDLFVFTDEIYEHFLYDGRRHHSPFALPGMRKRTVLISGFSKTFSVTGW
HHHHHHHHHHHCCEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCE
RIGYAISDARWAQAIGYFNDLVYVCAPSALQPGVAAGLATLDTSYYLSLSAEYGFKRNRF
EEEEEECCHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHCCCEEEEEEECCCCCCHHHH
CRALGEAGLNAVLPQGAYYVLADVSHLPGSTTRDKAMHILRTTGVASVPGSAFFRNENDQ
HHHHHHCCCCEECCCCCEEEEEEHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHCCCCCHH
HLVRFCYAKDDVVLDAACERLMKLKEMD
HEEEEECCCCCEEHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]