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The map label for this gene is purQ [H]

Identifier: 194334280

GI number: 194334280

Start: 1613460

End: 1614164

Strand: Reverse

Name: purQ [H]

Synonym: Paes_1473

Alternate gene names: 194334280

Gene position: 1614164-1613460 (Counterclockwise)

Preceding gene: 194334281

Following gene: 194334279

Centisome position: 64.23

GC content: 50.64

Gene sequence:

>705_bases
ATGGCTGATGTTACCATAGGCGTTGTTGTTTTTCCCGGATCGAACTGTGATCACGATACAGAGTATGCGGCAGCATCGTT
TCCCGGTGCAACAACAAGAATGCTGTGGCATAACGAACATGATCTTCAGGGTAGCGATATGATCGTTCTGCCCGGAGGAT
TTTCCTATGGCGATTACCTGAGAGCCGGTTCTATCGCCAGGTTTTCACCGATCATGCGAGAAGTTATAGCGTTTGCTGCA
AAAGGCAATCCTGTTCTGGGTATCTGCAACGGCTTTCAGGTGCTTCTCGAATCAGGACTGCTCGAAGGCGCTTTGACGAG
AAACCGTGAGAAGAAGTTTCTCTGCAGGTTTATGCCGGTCAAGGTCGTCAATAACAAAACCCTGTTCACGTCTCAATACA
AAGCAGGCGAAGTACTCAATCTGCCTGTCGCTCATGGTGAGGGCAACTACTACGCTTCGCAGGAAACTCTCGATAGTTTG
AAGGAGCATGATCAGGTTGTCTTTACCTATACCGATGCAGCAGGGAACCAGACCGATGCGGCGAACCTCAATGGTTCTGT
CGATTCCATAGCGGGTATAACCAACCGCTCGAAGAATGTTCTCGGTCTCATGCCTCACCCCGAGCGTGCCAGCGAAGCGC
TGCTGGGTTCCGGCGATGGCAGGAGGATGTTTCAGTCGGCTATAGAATATCTTGCCGGAAGGTAA

Upstream 100 bases:

>100_bases
GGAGCGCATTGCCGATGAGGCATGCCGCAAGCTGCTGGCCAATACCGTTATGGAGGATTATTCCATTGAACTCGAAAAAA
TCAACTAAACAGATCTGAGC

Downstream 100 bases:

>100_bases
CGACTATCCGCTCCAGGGTACCCGGATATCATCGATTTCCGGTACACTGGAGCAAGCTTTTTCCTCCTCGGTCGCTGCCT
GGCGTTTTTTCCCGCAACTG

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MADVTIGVVVFPGSNCDHDTEYAAASFPGATTRMLWHNEHDLQGSDMIVLPGGFSYGDYLRAGSIARFSPIMREVIAFAA
KGNPVLGICNGFQVLLESGLLEGALTRNREKKFLCRFMPVKVVNNKTLFTSQYKAGEVLNLPVAHGEGNYYASQETLDSL
KEHDQVVFTYTDAAGNQTDAANLNGSVDSIAGITNRSKNVLGLMPHPERASEALLGSGDGRRMFQSAIEYLAGR

Sequences:

>Translated_234_residues
MADVTIGVVVFPGSNCDHDTEYAAASFPGATTRMLWHNEHDLQGSDMIVLPGGFSYGDYLRAGSIARFSPIMREVIAFAA
KGNPVLGICNGFQVLLESGLLEGALTRNREKKFLCRFMPVKVVNNKTLFTSQYKAGEVLNLPVAHGEGNYYASQETLDSL
KEHDQVVFTYTDAAGNQTDAANLNGSVDSIAGITNRSKNVLGLMPHPERASEALLGSGDGRRMFQSAIEYLAGR
>Mature_233_residues
ADVTIGVVVFPGSNCDHDTEYAAASFPGATTRMLWHNEHDLQGSDMIVLPGGFSYGDYLRAGSIARFSPIMREVIAFAAK
GNPVLGICNGFQVLLESGLLEGALTRNREKKFLCRFMPVKVVNNKTLFTSQYKAGEVLNLPVAHGEGNYYASQETLDSLK
EHDQVVFTYTDAAGNQTDAANLNGSVDSIAGITNRSKNVLGLMPHPERASEALLGSGDGRRMFQSAIEYLAGR

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=178, Percent_Identity=34.8314606741573, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17553022, Length=196, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321498, Length=215, Percent_Identity=30.6976744186047, Blast_Score=69, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24582111, Length=204, Percent_Identity=32.843137254902, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24582109, Length=204, Percent_Identity=32.843137254902, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI17137292, Length=204, Percent_Identity=32.843137254902, Blast_Score=89, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR010075 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 25311; Mature: 25180

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADVTIGVVVFPGSNCDHDTEYAAASFPGATTRMLWHNEHDLQGSDMIVLPGGFSYGDYL
CCCEEEEEEEECCCCCCCCCCCHHHCCCCCEEEEEECCCCCCCCCCEEEECCCCCCHHHH
RAGSIARFSPIMREVIAFAAKGNPVLGICNGFQVLLESGLLEGALTRNREKKFLCRFMPV
HCCCCHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHCCHHHHHHCCCCHHHHHHCCCE
KVVNNKTLFTSQYKAGEVLNLPVAHGEGNYYASQETLDSLKEHDQVVFTYTDAAGNQTDA
EEECCCEEEECCCCCCCEEECEEEECCCCEEECHHHHHHHHHCCCEEEEEECCCCCCCCC
ANLNGSVDSIAGITNRSKNVLGLMPHPERASEALLGSGDGRRMFQSAIEYLAGR
CCCCCCHHHHHHCCCCCCCEEEECCCCCHHHHHHHCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
ADVTIGVVVFPGSNCDHDTEYAAASFPGATTRMLWHNEHDLQGSDMIVLPGGFSYGDYL
CCEEEEEEEECCCCCCCCCCCHHHCCCCCEEEEEECCCCCCCCCCEEEECCCCCCHHHH
RAGSIARFSPIMREVIAFAAKGNPVLGICNGFQVLLESGLLEGALTRNREKKFLCRFMPV
HCCCCHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHCCHHHHHHCCCCHHHHHHCCCE
KVVNNKTLFTSQYKAGEVLNLPVAHGEGNYYASQETLDSLKEHDQVVFTYTDAAGNQTDA
EEECCCEEEECCCCCCCEEECEEEECCCCEEECHHHHHHHHHCCCEEEEEECCCCCCCCC
ANLNGSVDSIAGITNRSKNVLGLMPHPERASEALLGSGDGRRMFQSAIEYLAGR
CCCCCCHHHHHHCCCCCCCEEEECCCCCHHHHHHHCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA