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The map label for this gene is yycF [H]

Identifier: 194334237

GI number: 194334237

Start: 1554269

End: 1554637

Strand: Reverse

Name: yycF [H]

Synonym: Paes_1429

Alternate gene names: 194334237

Gene position: 1554637-1554269 (Counterclockwise)

Preceding gene: 194334238

Following gene: 194334235

Centisome position: 61.87

GC content: 47.15

Gene sequence:

>369_bases
ATGAAACAGTCACGTATTCTCATCATTGATGACTCTGCAAGTATCAGACGTCTTCTTGCTCACAATCTGGGGAAGCGGTT
CGAGGTACTGGTTGCTGACAATGCGAATCATGCCCTTGAGCTGCTTGAGCAGGGAGTGACTCCTGATTTGGCTATTGTTG
ACGTCGCCATGCCGGGAATGGATGGTTTTTCTCTTGTTGAGCGATTGAAAAAAGACCCGTCATACAGCACAATACCAATT
ATCATGCTGACGGCCAGGGACGAAAGCGCTGATAAGGAAAAAGGTCTGAAGCTGGGCGCTGATGATTACCTGACCAAACC
CTTCAACACTGAAGATCTTGCTGACAGAATCGAACATCTGCTTGCATAA

Upstream 100 bases:

>100_bases
TTTGTGCGTCTTCCGTTATCGACATCCGGAAATTGAGCTATGTGTTTTTCTTTACGCCAGAGCCTGAAAACATCATCGAA
ACTGTAAAGCATTATCTACA

Downstream 100 bases:

>100_bases
ATGTGGTCGTACAAGGTTGCGTTCGGTAGGCTCGACCTTTTTCTTGCGCATGGTTTTGACTATTAGCAGGTGCTTTTTCT
CTCGAACCACTTATGGGTTT

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 122; Mature: 122

Protein sequence:

>122_residues
MKQSRILIIDDSASIRRLLAHNLGKRFEVLVADNANHALELLEQGVTPDLAIVDVAMPGMDGFSLVERLKKDPSYSTIPI
IMLTARDESADKEKGLKLGADDYLTKPFNTEDLADRIEHLLA

Sequences:

>Translated_122_residues
MKQSRILIIDDSASIRRLLAHNLGKRFEVLVADNANHALELLEQGVTPDLAIVDVAMPGMDGFSLVERLKKDPSYSTIPI
IMLTARDESADKEKGLKLGADDYLTKPFNTEDLADRIEHLLA
>Mature_122_residues
MKQSRILIIDDSASIRRLLAHNLGKRFEVLVADNANHALELLEQGVTPDLAIVDVAMPGMDGFSLVERLKKDPSYSTIPI
IMLTARDESADKEKGLKLGADDYLTKPFNTEDLADRIEHLLA

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG3706

COG function: function code T; Response regulator containing a CheY-like receiver domain and a GGDEF domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=118, Percent_Identity=37.2881355932203, Blast_Score=87, Evalue=2e-19,
Organism=Escherichia coli, GI1789809, Length=118, Percent_Identity=38.9830508474576, Blast_Score=78, Evalue=2e-16,
Organism=Escherichia coli, GI1787375, Length=122, Percent_Identity=37.7049180327869, Blast_Score=75, Evalue=1e-15,
Organism=Escherichia coli, GI1788394, Length=118, Percent_Identity=33.0508474576271, Blast_Score=74, Evalue=2e-15,
Organism=Escherichia coli, GI1786911, Length=116, Percent_Identity=37.9310344827586, Blast_Score=73, Evalue=5e-15,
Organism=Escherichia coli, GI1788550, Length=112, Percent_Identity=37.5, Blast_Score=71, Evalue=2e-14,
Organism=Escherichia coli, GI1790860, Length=130, Percent_Identity=30, Blast_Score=69, Evalue=8e-14,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=30.8943089430894, Blast_Score=66, Evalue=8e-13,
Organism=Escherichia coli, GI1790863, Length=123, Percent_Identity=32.520325203252, Blast_Score=65, Evalue=1e-12,
Organism=Escherichia coli, GI1787487, Length=106, Percent_Identity=41.5094339622642, Blast_Score=65, Evalue=1e-12,
Organism=Escherichia coli, GI1790552, Length=118, Percent_Identity=36.4406779661017, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1789402, Length=118, Percent_Identity=36.4406779661017, Blast_Score=64, Evalue=2e-12,
Organism=Escherichia coli, GI87082012, Length=119, Percent_Identity=32.7731092436975, Blast_Score=64, Evalue=4e-12,
Organism=Escherichia coli, GI1786784, Length=118, Percent_Identity=35.5932203389831, Blast_Score=62, Evalue=7e-12,
Organism=Escherichia coli, GI2367329, Length=119, Percent_Identity=40.3361344537815, Blast_Score=60, Evalue=5e-11,
Organism=Escherichia coli, GI145693157, Length=103, Percent_Identity=35.9223300970874, Blast_Score=60, Evalue=5e-11,
Organism=Escherichia coli, GI1787229, Length=121, Percent_Identity=29.7520661157025, Blast_Score=59, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 13529; Mature: 13529

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQSRILIIDDSASIRRLLAHNLGKRFEVLVADNANHALELLEQGVTPDLAIVDVAMPGM
CCCCCEEEEECCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHCCCCCCEEEEEEECCCC
DGFSLVERLKKDPSYSTIPIIMLTARDESADKEKGLKLGADDYLTKPFNTEDLADRIEHL
CHHHHHHHHHCCCCCCCEEEEEEEECCCCCCHHCCCEECCCCCCCCCCCHHHHHHHHHHH
LA
CC
>Mature Secondary Structure
MKQSRILIIDDSASIRRLLAHNLGKRFEVLVADNANHALELLEQGVTPDLAIVDVAMPGM
CCCCCEEEEECCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHCCCCCCEEEEEEECCCC
DGFSLVERLKKDPSYSTIPIIMLTARDESADKEKGLKLGADDYLTKPFNTEDLADRIEHL
CHHHHHHHHHCCCCCCCEEEEEEEECCCCCCHHCCCEECCCCCCCCCCCHHHHHHHHHHH
LA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]