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The map label for this gene is 194334162

Identifier: 194334162

GI number: 194334162

Start: 1472209

End: 1473402

Strand: Reverse

Name: 194334162

Synonym: Paes_1353

Alternate gene names: NA

Gene position: 1473402-1472209 (Counterclockwise)

Preceding gene: 194334163

Following gene: 194334161

Centisome position: 58.63

GC content: 47.15

Gene sequence:

>1194_bases
ATGCGCAATATCATTTTTACGGGTAAGGGAGGCGTTGGAAAAACCTCTGTTGCAGCCGCAACAGCACTGAAAGCTGCTGA
CATGGGTTATAAAACCCTGATAATGTCTACTGATCCCGCTCACAGTCTCGGTGATTCACTTGATGTGCAGCTTGGCCCTT
CCCCTGTCAAGGTTGCTGAAAATCTCTGGGGTCAGGAAGTCAGTGTTTTCGGTGATCTGAACCTGAACTGGGATGTTGTT
CGGGAACACTTTGCTCAGCTAATGGAATCAAGAGGTGTAGAGGGTATTTATGCTGAAGAGATGGGTGTCCTTCCTGGTAT
GGAAGAGCTTTTCTCTCTCTCCTACATCAAACGTTATAACGAAGAAGAGTCCGATTACGACCTGCTTGTCGTTGACTGTG
CTCCTACCGGCGAAACGCTTCGTCTCCTTTCACTTCCCGAGACATTCGGCTGGTTTATCAAGCTGATCCGCAACGTTGAG
AAATATATGGTCAAGCCAATGATCAGGCCGCTCTCCAAAAAGGTCAAGAAAATTGACTCGATGGTCGCACCTGAAGAGGT
TTACGAGAAAGTCGACAATCTGTTCGCTTCAACAGAAGGCATCATCGAGCTGCTTGCCGACGGTTCAAAATCGACCGTTC
GTCTTGTTATGAACCCTGAAAAGATGGTTATCAAAGAGTCCATGAGGGCGCTGACCTATCTCAACCTCTATGGCATCACT
GTTGACAGCATCACTATCAACAGAGTCATGCCTGCTCATACCGAGGATCCTTATTTCAAGAAATGGAGAGATATTCAGCA
GAATTATATCAAACAGATTGAAGGTTCATTCGCGCCTATTCCGATCGGCCAGGTTCCTTTGTTTGATCAGGAGGTCGTCG
GTCTTGACATGCTTCGTCAGGTTGGTGAGAAAGTCTATGCCGAAAAGAATCCTGTCGATATTTTCTTCAAGGAAGACCCG
ATTGCTATTGAGAAGGTCAACGATGGTCACTACAAGGTTCGAGTGAAATTGCCATTTATGGAAACTATGGGACAGGAGCC
CAAGATCCTTAAGCTCGGCGATGATCTTACCATCAGAATTGGCGATTATCAGAAGGTTGTCGCTCTGCCGATCTTTATTG
CCGGACTTGAATCTTCCGGAGCGAGCTTTGACAACGGCTGGCTCAGCATCGACTTTACCAGGGACGGCGAGTAA

Upstream 100 bases:

>100_bases
TTAAGCCTTTTACTAAACAGGACGTTCGGGGACATGGAGAGCTTTGCGGGTCTTCTGTTCTTCTTTTTCAACTTCCATTA
AATGAGAATCATTACAACGT

Downstream 100 bases:

>100_bases
GGGTTTTCGTCCCGGTATTGCACGGTCTGTATTTTCGAAAACCTGCCTCAAAAAGGCAGGTTTTCGTGTTTAAGAGCCGA
AGGAATTAATTGCATCGATA

Product: arsenite-activated ATPase ArsA

Products: NA

Alternate protein names: Arsenical resistance ATPase; Arsenite-translocating ATPase; Arsenite-transporting ATPase [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MRNIIFTGKGGVGKTSVAAATALKAADMGYKTLIMSTDPAHSLGDSLDVQLGPSPVKVAENLWGQEVSVFGDLNLNWDVV
REHFAQLMESRGVEGIYAEEMGVLPGMEELFSLSYIKRYNEEESDYDLLVVDCAPTGETLRLLSLPETFGWFIKLIRNVE
KYMVKPMIRPLSKKVKKIDSMVAPEEVYEKVDNLFASTEGIIELLADGSKSTVRLVMNPEKMVIKESMRALTYLNLYGIT
VDSITINRVMPAHTEDPYFKKWRDIQQNYIKQIEGSFAPIPIGQVPLFDQEVVGLDMLRQVGEKVYAEKNPVDIFFKEDP
IAIEKVNDGHYKVRVKLPFMETMGQEPKILKLGDDLTIRIGDYQKVVALPIFIAGLESSGASFDNGWLSIDFTRDGE

Sequences:

>Translated_397_residues
MRNIIFTGKGGVGKTSVAAATALKAADMGYKTLIMSTDPAHSLGDSLDVQLGPSPVKVAENLWGQEVSVFGDLNLNWDVV
REHFAQLMESRGVEGIYAEEMGVLPGMEELFSLSYIKRYNEEESDYDLLVVDCAPTGETLRLLSLPETFGWFIKLIRNVE
KYMVKPMIRPLSKKVKKIDSMVAPEEVYEKVDNLFASTEGIIELLADGSKSTVRLVMNPEKMVIKESMRALTYLNLYGIT
VDSITINRVMPAHTEDPYFKKWRDIQQNYIKQIEGSFAPIPIGQVPLFDQEVVGLDMLRQVGEKVYAEKNPVDIFFKEDP
IAIEKVNDGHYKVRVKLPFMETMGQEPKILKLGDDLTIRIGDYQKVVALPIFIAGLESSGASFDNGWLSIDFTRDGE
>Mature_397_residues
MRNIIFTGKGGVGKTSVAAATALKAADMGYKTLIMSTDPAHSLGDSLDVQLGPSPVKVAENLWGQEVSVFGDLNLNWDVV
REHFAQLMESRGVEGIYAEEMGVLPGMEELFSLSYIKRYNEEESDYDLLVVDCAPTGETLRLLSLPETFGWFIKLIRNVE
KYMVKPMIRPLSKKVKKIDSMVAPEEVYEKVDNLFASTEGIIELLADGSKSTVRLVMNPEKMVIKESMRALTYLNLYGIT
VDSITINRVMPAHTEDPYFKKWRDIQQNYIKQIEGSFAPIPIGQVPLFDQEVVGLDMLRQVGEKVYAEKNPVDIFFKEDP
IAIEKVNDGHYKVRVKLPFMETMGQEPKILKLGDDLTIRIGDYQKVVALPIFIAGLESSGASFDNGWLSIDFTRDGE

Specific function: Anion-transporting ATPase. Catalyzes the extrusion of arsenite [H]

COG id: COG0003

COG function: function code P; Oxyanion-translocating ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arsA ATPase family [H]

Homologues:

Organism=Homo sapiens, GI50428938, Length=286, Percent_Identity=25.1748251748252, Blast_Score=79, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17557003, Length=317, Percent_Identity=23.9747634069401, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6320103, Length=323, Percent_Identity=25.6965944272446, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24586297, Length=305, Percent_Identity=25.2459016393443, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003348 [H]

Pfam domain/function: NA

EC number: =3.6.3.16 [H]

Molecular weight: Translated: 44537; Mature: 44537

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNIIFTGKGGVGKTSVAAATALKAADMGYKTLIMSTDPAHSLGDSLDVQLGPSPVKVAE
CCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHCCCCCEEEECCCHHHHHH
NLWGQEVSVFGDLNLNWDVVREHFAQLMESRGVEGIYAEEMGVLPGMEELFSLSYIKRYN
HCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEHHHHCCCCCHHHHHHHHHHHHCC
EEESDYDLLVVDCAPTGETLRLLSLPETFGWFIKLIRNVEKYMVKPMIRPLSKKVKKIDS
CCCCCCCEEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MVAPEEVYEKVDNLFASTEGIIELLADGSKSTVRLVMNPEKMVIKESMRALTYLNLYGIT
HCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHEEEEEE
VDSITINRVMPAHTEDPYFKKWRDIQQNYIKQIEGSFAPIPIGQVPLFDQEVVGLDMLRQ
EEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHH
VGEKVYAEKNPVDIFFKEDPIAIEKVNDGHYKVRVKLPFMETMGQEPKILKLGDDLTIRI
HHHHHHCCCCCEEEEECCCCEEEEEECCCEEEEEEEECHHHHCCCCCCEEEECCCEEEEE
GDYQKVVALPIFIAGLESSGASFDNGWLSIDFTRDGE
CCCHHHHHHHHEEEECCCCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MRNIIFTGKGGVGKTSVAAATALKAADMGYKTLIMSTDPAHSLGDSLDVQLGPSPVKVAE
CCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHCCCCCEEEECCCHHHHHH
NLWGQEVSVFGDLNLNWDVVREHFAQLMESRGVEGIYAEEMGVLPGMEELFSLSYIKRYN
HCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEHHHHCCCCCHHHHHHHHHHHHCC
EEESDYDLLVVDCAPTGETLRLLSLPETFGWFIKLIRNVEKYMVKPMIRPLSKKVKKIDS
CCCCCCCEEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MVAPEEVYEKVDNLFASTEGIIELLADGSKSTVRLVMNPEKMVIKESMRALTYLNLYGIT
HCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHEEEEEE
VDSITINRVMPAHTEDPYFKKWRDIQQNYIKQIEGSFAPIPIGQVPLFDQEVVGLDMLRQ
EEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHH
VGEKVYAEKNPVDIFFKEDPIAIEKVNDGHYKVRVKLPFMETMGQEPKILKLGDDLTIRI
HHHHHHCCCCCEEEEECCCCEEEEEECCCEEEEEEEECHHHHCCCCCCEEEECCCEEEEE
GDYQKVVALPIFIAGLESSGASFDNGWLSIDFTRDGE
CCCHHHHHHHHEEEECCCCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]