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The map label for this gene is aroF [H]

Identifier: 194334161

GI number: 194334161

Start: 1470965

End: 1472035

Strand: Reverse

Name: aroF [H]

Synonym: Paes_1352

Alternate gene names: 194334161

Gene position: 1472035-1470965 (Counterclockwise)

Preceding gene: 194334162

Following gene: 194334160

Centisome position: 58.58

GC content: 50.05

Gene sequence:

>1071_bases
ATGCAGCAATTACAGGATTTACGTGTTTCAAACATTACTCGACTGACTGCACCGCAAACCTTCAAGCAACGCCTTCCGGT
GACGGAAGAGATTGCCAGAACGGTTTTAGACGGTCGCGAGGAAGTTGAAAATATTTTATCCGGAAAAGATTCCCGGATGC
TTGTTATCGTCGGTCCGTGTTCGATTCACGATATCAAGGCGGCAATGGAGTATGCCGTTCGACTCAAGGCTCTGCGCGAT
GAACTGAAGGATGATCTTTGTATCGTCATGCGTGTTTATTTCGAGAAACCAAGGACAACGATCGGCTGGAAAGGGTTTAT
CAACGACCCGCACCTCGATGGTTCATTTGATATCGAGCATGGATTGCATTATGCCCGCAAACTGCTTCTTGATATCAATG
CCCTGGGGCTTCCTACAGCTACGGAGTTTCTCGATCCGTTTACACCTCAGTATGTATCTGATCTTGTCAGCTGGGCGGCG
ATTGGAGCAAGAACCATCGAGTCTCAGACACATCGTCAGATGGCCAGCGGCCTGTCGATGCCGGTAGGGTTCAAGAACTC
CACCGATGGTCGTATTCAGGCTGCCATTGATGCATTACGGTCGGCCATGCATGCTCACAGTTTTCTTGGTATCGATCAGG
AGGGGCACAGCAGTGTCATCACCACGACGGGCAATCCGTTTGGCCATATTGTGCTGCGTGGCGGTTCCCAGAAGCCGAAC
TACGATCCGGACAATATTGCCGACGCTGAGCGGAGGCTGCAGGCAGCACATCTGCCATCTGCCATTATGGTTGATTGCAG
TCATGCCAATTCGGGGAAAAAGCATGAACAGCAGGCCAACGTCTGGGATAATATTGTCGAACAGCGCGTCAACGGTACGA
CAAGTATCATCGGCGTGATGATCGAAAGTAATCTGTTCTGCGGAAATCAGCCTTTTCCTGACGATCCATCTTCCCTGCAG
TACGGTGTTTCGATTACCGATGCCTGCATTGCATGGAATGAAACTGAGACGCTCTTAAGGAAAGGCGCGGTGAGACTTCA
TGAAGTGCTTCGAAAATCTGAGCTTTCTTAA

Upstream 100 bases:

>100_bases
GAGCCGAAGGAATTAATTGCATCGATACCTGATTATTTATAGTTGATTTTTTTATCTTCCATCGTGTTACGAATTACTGA
CGATTTTATTTCTGAAACGA

Downstream 100 bases:

>100_bases
GTAATATTTACACAATCAAGGGGACCTCAATGAATAGGGTGCCCTCAAGAAGGAGATCAACCAAATGAATATAGATCGTC
TTGTTTTTGCCATTGCCGGT

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MQQLQDLRVSNITRLTAPQTFKQRLPVTEEIARTVLDGREEVENILSGKDSRMLVIVGPCSIHDIKAAMEYAVRLKALRD
ELKDDLCIVMRVYFEKPRTTIGWKGFINDPHLDGSFDIEHGLHYARKLLLDINALGLPTATEFLDPFTPQYVSDLVSWAA
IGARTIESQTHRQMASGLSMPVGFKNSTDGRIQAAIDALRSAMHAHSFLGIDQEGHSSVITTTGNPFGHIVLRGGSQKPN
YDPDNIADAERRLQAAHLPSAIMVDCSHANSGKKHEQQANVWDNIVEQRVNGTTSIIGVMIESNLFCGNQPFPDDPSSLQ
YGVSITDACIAWNETETLLRKGAVRLHEVLRKSELS

Sequences:

>Translated_356_residues
MQQLQDLRVSNITRLTAPQTFKQRLPVTEEIARTVLDGREEVENILSGKDSRMLVIVGPCSIHDIKAAMEYAVRLKALRD
ELKDDLCIVMRVYFEKPRTTIGWKGFINDPHLDGSFDIEHGLHYARKLLLDINALGLPTATEFLDPFTPQYVSDLVSWAA
IGARTIESQTHRQMASGLSMPVGFKNSTDGRIQAAIDALRSAMHAHSFLGIDQEGHSSVITTTGNPFGHIVLRGGSQKPN
YDPDNIADAERRLQAAHLPSAIMVDCSHANSGKKHEQQANVWDNIVEQRVNGTTSIIGVMIESNLFCGNQPFPDDPSSLQ
YGVSITDACIAWNETETLLRKGAVRLHEVLRKSELS
>Mature_356_residues
MQQLQDLRVSNITRLTAPQTFKQRLPVTEEIARTVLDGREEVENILSGKDSRMLVIVGPCSIHDIKAAMEYAVRLKALRD
ELKDDLCIVMRVYFEKPRTTIGWKGFINDPHLDGSFDIEHGLHYARKLLLDINALGLPTATEFLDPFTPQYVSDLVSWAA
IGARTIESQTHRQMASGLSMPVGFKNSTDGRIQAAIDALRSAMHAHSFLGIDQEGHSSVITTTGNPFGHIVLRGGSQKPN
YDPDNIADAERRLQAAHLPSAIMVDCSHANSGKKHEQQANVWDNIVEQRVNGTTSIIGVMIESNLFCGNQPFPDDPSSLQ
YGVSITDACIAWNETETLLRKGAVRLHEVLRKSELS

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788953, Length=338, Percent_Identity=53.2544378698225, Blast_Score=391, Evalue=1e-110,
Organism=Escherichia coli, GI1786969, Length=339, Percent_Identity=55.4572271386431, Blast_Score=386, Evalue=1e-109,
Organism=Escherichia coli, GI1787996, Length=343, Percent_Identity=52.4781341107872, Blast_Score=369, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6319726, Length=351, Percent_Identity=49.8575498575499, Blast_Score=360, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6320240, Length=360, Percent_Identity=43.3333333333333, Blast_Score=320, Evalue=2e-88,

Paralogues:

None

Copy number: 2,200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 39463; Mature: 39463

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQLQDLRVSNITRLTAPQTFKQRLPVTEEIARTVLDGREEVENILSGKDSRMLVIVGPC
CCHHHHHHHHCCHHHCCCHHHHHHCCCHHHHHHHHHCCHHHHHHHHCCCCCEEEEEECCC
SIHDIKAAMEYAVRLKALRDELKDDLCIVMRVYFEKPRTTIGWKGFINDPHLDGSFDIEH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHH
GLHYARKLLLDINALGLPTATEFLDPFTPQYVSDLVSWAAIGARTIESQTHRQMASGLSM
HHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PVGFKNSTDGRIQAAIDALRSAMHAHSFLGIDQEGHSSVITTTGNPFGHIVLRGGSQKPN
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEEEECCCCCCC
YDPDNIADAERRLQAAHLPSAIMVDCSHANSGKKHEQQANVWDNIVEQRVNGTTSIIGVM
CCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHH
IESNLFCGNQPFPDDPSSLQYGVSITDACIAWNETETLLRKGAVRLHEVLRKSELS
HCCCEEECCCCCCCCCCCEEECCEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQQLQDLRVSNITRLTAPQTFKQRLPVTEEIARTVLDGREEVENILSGKDSRMLVIVGPC
CCHHHHHHHHCCHHHCCCHHHHHHCCCHHHHHHHHHCCHHHHHHHHCCCCCEEEEEECCC
SIHDIKAAMEYAVRLKALRDELKDDLCIVMRVYFEKPRTTIGWKGFINDPHLDGSFDIEH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHH
GLHYARKLLLDINALGLPTATEFLDPFTPQYVSDLVSWAAIGARTIESQTHRQMASGLSM
HHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PVGFKNSTDGRIQAAIDALRSAMHAHSFLGIDQEGHSSVITTTGNPFGHIVLRGGSQKPN
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEEEECCCCCCC
YDPDNIADAERRLQAAHLPSAIMVDCSHANSGKKHEQQANVWDNIVEQRVNGTTSIIGVM
CCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHH
IESNLFCGNQPFPDDPSSLQYGVSITDACIAWNETETLLRKGAVRLHEVLRKSELS
HCCCEEECCCCCCCCCCCEEECCEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6146618; 6396419; 9205837; 9278503; 1977738; 6104668; 2857723; 9056491 [H]