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The map label for this gene is xerC [H]

Identifier: 193214435

GI number: 193214435

Start: 844505

End: 845515

Strand: Direct

Name: xerC [H]

Synonym: Ctha_0718

Alternate gene names: 193214435

Gene position: 844505-845515 (Clockwise)

Preceding gene: 193214434

Following gene: 193214436

Centisome position: 25.64

GC content: 41.64

Gene sequence:

>1011_bases
ATGCAAGATAGTTTGAATACAAATGCCGGACATTCGCAGCTAACCGCGTTTCTGAAATATTTGGCAAACGAGCGCAACAT
GTCGGCCTACACGGTGACTGCGTATAGAAAAGATCTCTCGCAATTTCTCGAATTTCTCAAAAAGGAATTTGAGCTGCCCT
CCTCGCAAGACATTTCGTTAGCGGATGTTGAAACCTCAACGATTCGCCTATTTTTAGGGGAATTGCTCGACGCGGGCTAT
CAATCAAAAAGCATCGGCAGAAAGTTGGCTTCCGTGAAAAGCTTTTTCAAATTTCTTGTGTACATCAATCACCTTCCGGC
TTCGCCTGCGGCAAATGTGACAACGCCAAAAGCAAAGAAAACTTTACCAACTTTCTTGAACGAAACCCAAACCCAAACCC
TCTTTGATGAAATTTTAGACCATTTTAATGAAGCTTTTTACCACGACAACCGCGCAAAAAAACACGAAAAGGTGAATACG
CTTGAATGGGATTTTCGTTATAACAGAGATAGGGCAATTCTGGAAATGTTTTACAGTTGCGGACTTCGCTTGGCTGAGCT
AATTGGACTAAACATCATGGAACTGGATTTTCAGAACGGTTTTGTGAAAGTTTTAGGAAAAGGCAGAAAGCAAAGAATTA
TCCCACTGGGCGAATCAGCTCAAAAGACCTTAAAAAACTACCTTGAGATCAAGAAAAAATTTTTTGAGATGAAACGAAGC
AATGTGTTGGAGCGCGAGGCTGTGTTCGTTACGGAAAAAGGCAAAAGAGTTTATCCGGTACTCGTTCAAAGATTGGTTAA
AAAGTATTTATCCCCTGTTACTGAGCAAAAGAAAAAAAGTCCGCATGTTTTGCGACATACTTTCGCAACCCACTTGCTCA
ATAATGGCGCCGACCTTCGCAGCGTCAGTGAAATGTTAGGTCATAGTAATCTTTCAACAACTGAAATTTACACCCATATC
TCGTTTGAGCGGCTGAAACAAGTCTATCAGCAAGCTCATCCCAAAGCATAG

Upstream 100 bases:

>100_bases
GGTGGAAATGGCTGTTGGCAACCACACGCTGAATGATGTAAAAATTAGCGGTTACGCAATAACCGTGCTTACAGGAGAAA
TTTTCGTCTGATCAAAAAAT

Downstream 100 bases:

>100_bases
TTTACCTTAATGCTTGAAAAACCTCGAAGCGGACATTCGAGGAGTATTACCGTTCACTTATAAATCAATACTGGAAAGGA
GAACATTATGGACAGCCATC

Product: integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MQDSLNTNAGHSQLTAFLKYLANERNMSAYTVTAYRKDLSQFLEFLKKEFELPSSQDISLADVETSTIRLFLGELLDAGY
QSKSIGRKLASVKSFFKFLVYINHLPASPAANVTTPKAKKTLPTFLNETQTQTLFDEILDHFNEAFYHDNRAKKHEKVNT
LEWDFRYNRDRAILEMFYSCGLRLAELIGLNIMELDFQNGFVKVLGKGRKQRIIPLGESAQKTLKNYLEIKKKFFEMKRS
NVLEREAVFVTEKGKRVYPVLVQRLVKKYLSPVTEQKKKSPHVLRHTFATHLLNNGADLRSVSEMLGHSNLSTTEIYTHI
SFERLKQVYQQAHPKA

Sequences:

>Translated_336_residues
MQDSLNTNAGHSQLTAFLKYLANERNMSAYTVTAYRKDLSQFLEFLKKEFELPSSQDISLADVETSTIRLFLGELLDAGY
QSKSIGRKLASVKSFFKFLVYINHLPASPAANVTTPKAKKTLPTFLNETQTQTLFDEILDHFNEAFYHDNRAKKHEKVNT
LEWDFRYNRDRAILEMFYSCGLRLAELIGLNIMELDFQNGFVKVLGKGRKQRIIPLGESAQKTLKNYLEIKKKFFEMKRS
NVLEREAVFVTEKGKRVYPVLVQRLVKKYLSPVTEQKKKSPHVLRHTFATHLLNNGADLRSVSEMLGHSNLSTTEIYTHI
SFERLKQVYQQAHPKA
>Mature_336_residues
MQDSLNTNAGHSQLTAFLKYLANERNMSAYTVTAYRKDLSQFLEFLKKEFELPSSQDISLADVETSTIRLFLGELLDAGY
QSKSIGRKLASVKSFFKFLVYINHLPASPAANVTTPKAKKTLPTFLNETQTQTLFDEILDHFNEAFYHDNRAKKHEKVNT
LEWDFRYNRDRAILEMFYSCGLRLAELIGLNIMELDFQNGFVKVLGKGRKQRIIPLGESAQKTLKNYLEIKKKFFEMKRS
NVLEREAVFVTEKGKRVYPVLVQRLVKKYLSPVTEQKKKSPHVLRHTFATHLLNNGADLRSVSEMLGHSNLSTTEIYTHI
SFERLKQVYQQAHPKA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=327, Percent_Identity=35.1681957186544, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1790244, Length=326, Percent_Identity=34.6625766871166, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1790768, Length=165, Percent_Identity=23.6363636363636, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 38795; Mature: 38795

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDSLNTNAGHSQLTAFLKYLANERNMSAYTVTAYRKDLSQFLEFLKKEFELPSSQDISL
CCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
ADVETSTIRLFLGELLDAGYQSKSIGRKLASVKSFFKFLVYINHLPASPAANVTTPKAKK
ECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
TLPTFLNETQTQTLFDEILDHFNEAFYHDNRAKKHEKVNTLEWDFRYNRDRAILEMFYSC
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEECEEECCHHHHHHHHHHH
GLRLAELIGLNIMELDFQNGFVKVLGKGRKQRIIPLGESAQKTLKNYLEIKKKFFEMKRS
HHHHHHHHCCCCEEEECCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
NVLEREAVFVTEKGKRVYPVLVQRLVKKYLSPVTEQKKKSPHVLRHTFATHLLNNGADLR
HHHHHHHEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHH
SVSEMLGHSNLSTTEIYTHISFERLKQVYQQAHPKA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQDSLNTNAGHSQLTAFLKYLANERNMSAYTVTAYRKDLSQFLEFLKKEFELPSSQDISL
CCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
ADVETSTIRLFLGELLDAGYQSKSIGRKLASVKSFFKFLVYINHLPASPAANVTTPKAKK
ECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
TLPTFLNETQTQTLFDEILDHFNEAFYHDNRAKKHEKVNTLEWDFRYNRDRAILEMFYSC
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEECEEECCHHHHHHHHHHH
GLRLAELIGLNIMELDFQNGFVKVLGKGRKQRIIPLGESAQKTLKNYLEIKKKFFEMKRS
HHHHHHHHCCCCEEEECCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
NVLEREAVFVTEKGKRVYPVLVQRLVKKYLSPVTEQKKKSPHVLRHTFATHLLNNGADLR
HHHHHHHEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHH
SVSEMLGHSNLSTTEIYTHISFERLKQVYQQAHPKA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]