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The map label for this gene is ccmF [H]

Identifier: 193214335

GI number: 193214335

Start: 725796

End: 728105

Strand: Direct

Name: ccmF [H]

Synonym: Ctha_0617

Alternate gene names: 193214335

Gene position: 725796-728105 (Clockwise)

Preceding gene: 193214334

Following gene: 193214336

Centisome position: 22.04

GC content: 53.33

Gene sequence:

>2310_bases
ATGCTGTTTCATTTTTTGACGGGAAAATTTATCACGATTTTGGGCTTTGTGGCCGCCGTGCTTTCCATGTACGCTTATTT
TCGCTCGGCGCAAAACGAGCAAAAACCCGCCCTGCGCGACGAATGGCGCACGCACGGACGCGATTTCTTTTGGGTCATGT
TCGGCTCAATCTCGGTTAGCGGCCTGCATCTGCTCTACCTGATTTTGTCGCATCAATTCGAGTATAGCTATGTGAAGCAT
TACTCCTCCACCGACTTGAACTTGTTTTATCTCATCTCCACTTTTTATGCCGGGCAAGAAGGAAGCTTTCTGCTTTGGCT
CTTTTTTGCGGCGCTGTGCGGGATTTTCGTCATCCGCGCGGCGAAGGACTACGAGCCGCATGTCATGAGCGTTTTGACGC
TTTCGCAAGCGTTTTTGCTTTCGATGCTGCTCGGCATCGAGTTGCCCGTTATCGGCACCGTCGGCAGCGACCCGTTTACG
CTCGTGCCGGGCATCGTAAAGGACGCCTCGTTGTTTAGCCTCACGCTGAGCGCGATTCCCGAAGGCGACGGGCTGAATCC
GCTTTTGCAAAATCCATGGATGGTCATTCATCCGCCGACGCTTTTCGTCGGGTTTGCTTCATTGATTGTCCCGTTCGGCT
TTGCTATTGCGGCGATGTGGCGTCAGCGCTACGACGATTGGATTCGTCCGGCCATGCCATGGACGCTGTTCGGCACCGGC
TCGCTCGGGTTGGGCATCATCATGGGCGGCTATTGGGCGTATAAGGTGCTGGGCTGGGGCGGCTATTGGGGCTGGGACCC
GGTGGAAAATTCCTCGCTGGTGCCTTGGCTTGTCATGTCGGCGCTGATTCACACGATGATCGTGCAGAAAAAAAACGGCG
GCCTGAAACGCACCAACCTGTTGCTCGCCGTGTTGGCCTATGTTTTCGTGCTGTATAGCACCTTTTTAACCCGCAGCGGC
ATTCTGGGCGATTTTTCCGTCCATTCTTTTACCGATCTTGGGCTTTACAATCAGCTTCTCGTTTTCGTCATCGGCTTTTT
GGCGCTCGGCATCGGCTTTTTGCTTTTCCGCATGAGGACGATTCCGGTAAGAACCTCGAGCGAGGAAATTTTTTCGCGCG
AATATTTTCTGCTGGCCGGTTCGGTGGTTTTGCTGCTAATCAGCTTTGTCGTGGCCGCCGGCACGTCCGCGCCGATTTTG
AACCGACTTTTCACCGACCGCCCGAATCCGATTTTGCCCGAATTTTATAACCGCGTCACGCTTCCGCTGGCGATTCTCAT
CGGGCTGTTTTCCGCCGTCGGCCAATTGCTTTGGTGGAAAAAAATCGACAAGGAAACCTTGATGAAGGCTTTTGCCGTGC
CGCTTGGACTTTCTGTTTTCGGCACGGGCGCACTCGTGATTTTGGGCTTGCACGATCCGGCCATCGCGCTTTTTGCCTTT
GCGTCGTTCCTTTCACTTTTCGCCAACGGCCAAATGCTCGTCAAGATTTTATCGGGAAATCCGCGTTATATCGGCGGCTC
GCTGACGCATGTCGGGCTTGCGCTCATGTTGCTCGGCATTTTGGCCGGCTATTACGACCGCTCCGAACACGCCGAATTGC
CGAAGGGCGAGCCGGTGGAAATTTTTGGCAAAACGCTCACCTACACCGGCGCCCAAACGCCCGACGGCGAAAAAAACGAA
TACGTAATAAAAATCGAGGACGGCGATGAGACGCTGGAGGCAAAGCCCGTCATGTACGAAACGAACAACATGGTTGTGCA
AAACCCCGATGTGCTGCATTCTTTGACCAACGATTTTTACATCTCACCGGTCAATATCATGCTGAAGGGAAATCCGAATG
TGGCGACGCTTGGGCAAAACGAAACCAAGCGCATCGGCGACTATGAAGTCAAATTTGTCGGATTCAAGCTGCCAGAAAAA
ATCAAGCTCGATCCAAACGCTGCTAAACCGCTGCGCATTTTTGCGCTTTTGGCCGTCACGCACACGGGAAAAACCGATAC
GCTCAAGCCGGCCTTTACGCTTGCGCCGGGCAAAGAATCCCTGATCGAGCCGGACGCTTTGCCCGGCAATCCGAATATCA
AATTCGCCATGACGGATATTGATCCGAGGGATAAAAAGGTGCTGATAGAGGCCGTCGGCTTAAATCTCGAGCGTGAGGGC
TCGGACGAAACCTTGATTATCGAGGCGAGCCTGAAGCCGTTCATCAATGTGCTTTGGCTGGGGACGTATCTCGTCACGTT
CGGCTTTATCATTTCGATTTATCGCCGCTGGCGCGAACGCCGTTTTGAAGACGAGATCGAAGAAGATTAG

Upstream 100 bases:

>100_bases
AAATAACATTTTGGTGAAATGCCCCTCGAAATATCAATCCGAAAAAGCCGATACCAAAAAGACCTGATTTTTCAACGCCG
ATTGCCGTAACTCATTTCTT

Downstream 100 bases:

>100_bases
TTTTTTGCGCTAAAAATCTTGCGCTGAACAGCCTTGCCCTTTTCGGAAAAACGTACCCTTTTCATAGAAAACATTTCATC
AATTTTTTTACCGAACCCAA

Product: cytochrome c assembly protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 769; Mature: 769

Protein sequence:

>769_residues
MLFHFLTGKFITILGFVAAVLSMYAYFRSAQNEQKPALRDEWRTHGRDFFWVMFGSISVSGLHLLYLILSHQFEYSYVKH
YSSTDLNLFYLISTFYAGQEGSFLLWLFFAALCGIFVIRAAKDYEPHVMSVLTLSQAFLLSMLLGIELPVIGTVGSDPFT
LVPGIVKDASLFSLTLSAIPEGDGLNPLLQNPWMVIHPPTLFVGFASLIVPFGFAIAAMWRQRYDDWIRPAMPWTLFGTG
SLGLGIIMGGYWAYKVLGWGGYWGWDPVENSSLVPWLVMSALIHTMIVQKKNGGLKRTNLLLAVLAYVFVLYSTFLTRSG
ILGDFSVHSFTDLGLYNQLLVFVIGFLALGIGFLLFRMRTIPVRTSSEEIFSREYFLLAGSVVLLLISFVVAAGTSAPIL
NRLFTDRPNPILPEFYNRVTLPLAILIGLFSAVGQLLWWKKIDKETLMKAFAVPLGLSVFGTGALVILGLHDPAIALFAF
ASFLSLFANGQMLVKILSGNPRYIGGSLTHVGLALMLLGILAGYYDRSEHAELPKGEPVEIFGKTLTYTGAQTPDGEKNE
YVIKIEDGDETLEAKPVMYETNNMVVQNPDVLHSLTNDFYISPVNIMLKGNPNVATLGQNETKRIGDYEVKFVGFKLPEK
IKLDPNAAKPLRIFALLAVTHTGKTDTLKPAFTLAPGKESLIEPDALPGNPNIKFAMTDIDPRDKKVLIEAVGLNLEREG
SDETLIIEASLKPFINVLWLGTYLVTFGFIISIYRRWRERRFEDEIEED

Sequences:

>Translated_769_residues
MLFHFLTGKFITILGFVAAVLSMYAYFRSAQNEQKPALRDEWRTHGRDFFWVMFGSISVSGLHLLYLILSHQFEYSYVKH
YSSTDLNLFYLISTFYAGQEGSFLLWLFFAALCGIFVIRAAKDYEPHVMSVLTLSQAFLLSMLLGIELPVIGTVGSDPFT
LVPGIVKDASLFSLTLSAIPEGDGLNPLLQNPWMVIHPPTLFVGFASLIVPFGFAIAAMWRQRYDDWIRPAMPWTLFGTG
SLGLGIIMGGYWAYKVLGWGGYWGWDPVENSSLVPWLVMSALIHTMIVQKKNGGLKRTNLLLAVLAYVFVLYSTFLTRSG
ILGDFSVHSFTDLGLYNQLLVFVIGFLALGIGFLLFRMRTIPVRTSSEEIFSREYFLLAGSVVLLLISFVVAAGTSAPIL
NRLFTDRPNPILPEFYNRVTLPLAILIGLFSAVGQLLWWKKIDKETLMKAFAVPLGLSVFGTGALVILGLHDPAIALFAF
ASFLSLFANGQMLVKILSGNPRYIGGSLTHVGLALMLLGILAGYYDRSEHAELPKGEPVEIFGKTLTYTGAQTPDGEKNE
YVIKIEDGDETLEAKPVMYETNNMVVQNPDVLHSLTNDFYISPVNIMLKGNPNVATLGQNETKRIGDYEVKFVGFKLPEK
IKLDPNAAKPLRIFALLAVTHTGKTDTLKPAFTLAPGKESLIEPDALPGNPNIKFAMTDIDPRDKKVLIEAVGLNLEREG
SDETLIIEASLKPFINVLWLGTYLVTFGFIISIYRRWRERRFEDEIEED
>Mature_769_residues
MLFHFLTGKFITILGFVAAVLSMYAYFRSAQNEQKPALRDEWRTHGRDFFWVMFGSISVSGLHLLYLILSHQFEYSYVKH
YSSTDLNLFYLISTFYAGQEGSFLLWLFFAALCGIFVIRAAKDYEPHVMSVLTLSQAFLLSMLLGIELPVIGTVGSDPFT
LVPGIVKDASLFSLTLSAIPEGDGLNPLLQNPWMVIHPPTLFVGFASLIVPFGFAIAAMWRQRYDDWIRPAMPWTLFGTG
SLGLGIIMGGYWAYKVLGWGGYWGWDPVENSSLVPWLVMSALIHTMIVQKKNGGLKRTNLLLAVLAYVFVLYSTFLTRSG
ILGDFSVHSFTDLGLYNQLLVFVIGFLALGIGFLLFRMRTIPVRTSSEEIFSREYFLLAGSVVLLLISFVVAAGTSAPIL
NRLFTDRPNPILPEFYNRVTLPLAILIGLFSAVGQLLWWKKIDKETLMKAFAVPLGLSVFGTGALVILGLHDPAIALFAF
ASFLSLFANGQMLVKILSGNPRYIGGSLTHVGLALMLLGILAGYYDRSEHAELPKGEPVEIFGKTLTYTGAQTPDGEKNE
YVIKIEDGDETLEAKPVMYETNNMVVQNPDVLHSLTNDFYISPVNIMLKGNPNVATLGQNETKRIGDYEVKFVGFKLPEK
IKLDPNAAKPLRIFALLAVTHTGKTDTLKPAFTLAPGKESLIEPDALPGNPNIKFAMTDIDPRDKKVLIEAVGLNLEREG
SDETLIIEASLKPFINVLWLGTYLVTFGFIISIYRRWRERRFEDEIEED

Specific function: Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase [H]

COG id: COG1138

COG function: function code O; Cytochrome c biogenesis factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ccmF/cycK/ccl1/nrfE/ccsA family [H]

Homologues:

Organism=Escherichia coli, GI1788524, Length=608, Percent_Identity=30.0986842105263, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI1790511, Length=252, Percent_Identity=35.7142857142857, Blast_Score=141, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003567
- InterPro:   IPR003568 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 85718; Mature: 85718

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFHFLTGKFITILGFVAAVLSMYAYFRSAQNEQKPALRDEWRTHGRDFFWVMFGSISVS
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCEEEEEEECCCCHH
GLHLLYLILSHQFEYSYVKHYSSTDLNLFYLISTFYAGQEGSFLLWLFFAALCGIFVIRA
HHHHHHHHHHCCCCHHHHHHCCCCCCCHHEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
AKDYEPHVMSVLTLSQAFLLSMLLGIELPVIGTVGSDPFTLVPGIVKDASLFSLTLSAIP
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEECCCHHCCCHHHEEEEHHCC
EGDGLNPLLQNPWMVIHPPTLFVGFASLIVPFGFAIAAMWRQRYDDWIRPAMPWTLFGTG
CCCCCCHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
SLGLGIIMGGYWAYKVLGWGGYWGWDPVENSSLVPWLVMSALIHTMIVQKKNGGLKRTNL
CCCHHHHHCCCEEEHEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHH
LLAVLAYVFVLYSTFLTRSGILGDFSVHSFTDLGLYNQLLVFVIGFLALGIGFLLFRMRT
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPVRTSSEEIFSREYFLLAGSVVLLLISFVVAAGTSAPILNRLFTDRPNPILPEFYNRVT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCHHHHHHHH
LPLAILIGLFSAVGQLLWWKKIDKETLMKAFAVPLGLSVFGTGALVILGLHDPAIALFAF
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHEECCCEEEEEECCCHHHHHHHH
ASFLSLFANGQMLVKILSGNPRYIGGSLTHVGLALMLLGILAGYYDRSEHAELPKGEPVE
HHHHHHHHCCEEEEEEECCCCCEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
IFGKTLTYTGAQTPDGEKNEYVIKIEDGDETLEAKPVMYETNNMVVQNPDVLHSLTNDFY
EECCEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCEEEECCHHHHHHCCCEE
ISPVNIMLKGNPNVATLGQNETKRIGDYEVKFVGFKLPEKIKLDPNAAKPLRIFALLAVT
ECCEEEEEECCCCEEECCCCCCCCCCCEEEEEEEECCCCCEEECCCCCCHHHHHHHHHHC
HTGKTDTLKPAFTLAPGKESLIEPDALPGNPNIKFAMTDIDPRDKKVLIEAVGLNLEREG
CCCCCCCCCCCEEECCCCHHCCCCCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCC
SDETLIIEASLKPFINVLWLGTYLVTFGFIISIYRRWRERRFEDEIEED
CCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCC
>Mature Secondary Structure
MLFHFLTGKFITILGFVAAVLSMYAYFRSAQNEQKPALRDEWRTHGRDFFWVMFGSISVS
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCEEEEEEECCCCHH
GLHLLYLILSHQFEYSYVKHYSSTDLNLFYLISTFYAGQEGSFLLWLFFAALCGIFVIRA
HHHHHHHHHHCCCCHHHHHHCCCCCCCHHEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
AKDYEPHVMSVLTLSQAFLLSMLLGIELPVIGTVGSDPFTLVPGIVKDASLFSLTLSAIP
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEECCCHHCCCHHHEEEEHHCC
EGDGLNPLLQNPWMVIHPPTLFVGFASLIVPFGFAIAAMWRQRYDDWIRPAMPWTLFGTG
CCCCCCHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
SLGLGIIMGGYWAYKVLGWGGYWGWDPVENSSLVPWLVMSALIHTMIVQKKNGGLKRTNL
CCCHHHHHCCCEEEHEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHH
LLAVLAYVFVLYSTFLTRSGILGDFSVHSFTDLGLYNQLLVFVIGFLALGIGFLLFRMRT
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPVRTSSEEIFSREYFLLAGSVVLLLISFVVAAGTSAPILNRLFTDRPNPILPEFYNRVT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCHHHHHHHH
LPLAILIGLFSAVGQLLWWKKIDKETLMKAFAVPLGLSVFGTGALVILGLHDPAIALFAF
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHEECCCEEEEEECCCHHHHHHHH
ASFLSLFANGQMLVKILSGNPRYIGGSLTHVGLALMLLGILAGYYDRSEHAELPKGEPVE
HHHHHHHHCCEEEEEEECCCCCEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
IFGKTLTYTGAQTPDGEKNEYVIKIEDGDETLEAKPVMYETNNMVVQNPDVLHSLTNDFY
EECCEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCEEEECCHHHHHHCCCEE
ISPVNIMLKGNPNVATLGQNETKRIGDYEVKFVGFKLPEKIKLDPNAAKPLRIFALLAVT
ECCEEEEEECCCCEEECCCCCCCCCCCEEEEEEEECCCCCEEECCCCCCHHHHHHHHHHC
HTGKTDTLKPAFTLAPGKESLIEPDALPGNPNIKFAMTDIDPRDKKVLIEAVGLNLEREG
CCCCCCCCCCCEEECCCCHHCCCCCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCC
SDETLIIEASLKPFINVLWLGTYLVTFGFIISIYRRWRERRFEDEIEED
CCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 7635817 [H]