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The map label for this gene is waaA [H]

Identifier: 193214233

GI number: 193214233

Start: 610769

End: 612097

Strand: Direct

Name: waaA [H]

Synonym: Ctha_0514

Alternate gene names: 193214233

Gene position: 610769-612097 (Clockwise)

Preceding gene: 193214230

Following gene: 193214234

Centisome position: 18.54

GC content: 46.73

Gene sequence:

>1329_bases
ATGCAGCGCGCATGGCTTAGAGCCTATAATATTTTATTTCCACTGTTTCTTTTCTCTTTGAAAATTCTTGGATTCTTCAA
CGCCAAAATTCGGGCAACGCTTTTGGGACGAGAAAATCTCTTTCAACGCATTCGCGCCAAACAAAAAGCGCTGACGCATA
AAAGCGGATTTCGACTTTGGGTACACGCAGCTTCTGTTGGAGAATTTGAACAAGCTCGCCCAATTGTGAAAGCCATTCGC
GAAAAAGATCCCGACGCTGCCATTATCCTGACCTTTCTCTCCGTTTCTGGCTACGAAGCTCGAAAAAACACCAAAGAAGC
CGACCTTGTCACTTATTTGCCCGCCGATACGCCCAGCAACGCTCGCAAGTTTTTGGATTTACTTCAGCCCGATGCGCTCT
TGCTCATGCGCTACGATTTCTGGCCAAACCATTTATTCGAAGCCAAACGACGCGGCATTTATCTGATGCTGGCGGCGGCA
GTTCTTCAGCCAGATTCAACCTATAACAAGCCGATTATTCGCGGATTTTATCAAACCATTTTTTCGCTTTTCGATCAGAT
TTTTACCGTCGCTGAAGACGACGCCAAAAATTTCAAAACGCTATTCGGACTGGACCGCGTTCAGCAAGCCGGCGAACCCA
GAATTGATCAAGTGATTTGGCGCAGTCAGCAGCAAGAACGCGTCGCGCACTTGAAGCCGATCTACAACGAGCGATTAGTT
CTTGTGGCCGGAAGTGTTTGGAAAACAGATGAAGCCCATTTGATTCCTGCGTATCAATCGGTTAGGGAAAAATTGCTAAA
CTATCCAATTTCTTTGATTTTAGTCCCGCATGAAATCGGCCAGGAAAACCTGAATCGAATGGCCGATGATCTGAAATCGA
AACATCTGAGCTATCAATTTATCAGTCGATTGCATAGCAATTTCAACACAGAAACCGTGCTCATCATTGATGAAATCGGT
TATTTAGCGGAGCTTTATTCACTTGCGCACATCGCGTATATTGGCGGCGGATTTGGGGTTCATGTGCATAACACGCTCGA
AGCCGCGGTTTATCATTTGCCCTTGATTTATGGACCGCACTTTCATAAGTCGCCAGAAGCCAAAGCATTTCAGAAACTTG
GCGGCGCTACGGTTGTGTCAAACACCCAGTCGCTGGAAAAAATCCTTTACGACTTGTTTTCAACCGATGAACTTCGGGAA
AAAATGGGCAAAATTGCAGGAAACTATGTTCATTCGCGCGCGGGCGCAACGCAGAAAATCGCCGGTGCTTTGCTGCCTGC
GCAAAAAAACGCGCCGCCTCATCGTGGAAACACGCTCAACGCAACATGA

Upstream 100 bases:

>100_bases
AGCCGCATTAGAAACGAAACTCCAGGATGGATTAACAATTATGAAATTATACCAGCATTGCTAAATTATAATACTTTTCG
GGACTTAATAACAAATACTT

Downstream 100 bases:

>100_bases
TTTTTTCAGACGAACTTTCGCTTTCAATCTTTAAAATCTTCACCATGATTTCTAAAACACGGCTCTTTCTGCTTTTCTTT
TTCTTTCTCATGGCAACGCT

Product: 3-deoxy-D-manno-octulosonic-acid transferase domain-containing protein

Products: NA

Alternate protein names: KDO transferase [H]

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MQRAWLRAYNILFPLFLFSLKILGFFNAKIRATLLGRENLFQRIRAKQKALTHKSGFRLWVHAASVGEFEQARPIVKAIR
EKDPDAAIILTFLSVSGYEARKNTKEADLVTYLPADTPSNARKFLDLLQPDALLLMRYDFWPNHLFEAKRRGIYLMLAAA
VLQPDSTYNKPIIRGFYQTIFSLFDQIFTVAEDDAKNFKTLFGLDRVQQAGEPRIDQVIWRSQQQERVAHLKPIYNERLV
LVAGSVWKTDEAHLIPAYQSVREKLLNYPISLILVPHEIGQENLNRMADDLKSKHLSYQFISRLHSNFNTETVLIIDEIG
YLAELYSLAHIAYIGGGFGVHVHNTLEAAVYHLPLIYGPHFHKSPEAKAFQKLGGATVVSNTQSLEKILYDLFSTDELRE
KMGKIAGNYVHSRAGATQKIAGALLPAQKNAPPHRGNTLNAT

Sequences:

>Translated_442_residues
MQRAWLRAYNILFPLFLFSLKILGFFNAKIRATLLGRENLFQRIRAKQKALTHKSGFRLWVHAASVGEFEQARPIVKAIR
EKDPDAAIILTFLSVSGYEARKNTKEADLVTYLPADTPSNARKFLDLLQPDALLLMRYDFWPNHLFEAKRRGIYLMLAAA
VLQPDSTYNKPIIRGFYQTIFSLFDQIFTVAEDDAKNFKTLFGLDRVQQAGEPRIDQVIWRSQQQERVAHLKPIYNERLV
LVAGSVWKTDEAHLIPAYQSVREKLLNYPISLILVPHEIGQENLNRMADDLKSKHLSYQFISRLHSNFNTETVLIIDEIG
YLAELYSLAHIAYIGGGFGVHVHNTLEAAVYHLPLIYGPHFHKSPEAKAFQKLGGATVVSNTQSLEKILYDLFSTDELRE
KMGKIAGNYVHSRAGATQKIAGALLPAQKNAPPHRGNTLNAT
>Mature_442_residues
MQRAWLRAYNILFPLFLFSLKILGFFNAKIRATLLGRENLFQRIRAKQKALTHKSGFRLWVHAASVGEFEQARPIVKAIR
EKDPDAAIILTFLSVSGYEARKNTKEADLVTYLPADTPSNARKFLDLLQPDALLLMRYDFWPNHLFEAKRRGIYLMLAAA
VLQPDSTYNKPIIRGFYQTIFSLFDQIFTVAEDDAKNFKTLFGLDRVQQAGEPRIDQVIWRSQQQERVAHLKPIYNERLV
LVAGSVWKTDEAHLIPAYQSVREKLLNYPISLILVPHEIGQENLNRMADDLKSKHLSYQFISRLHSNFNTETVLIIDEIG
YLAELYSLAHIAYIGGGFGVHVHNTLEAAVYHLPLIYGPHFHKSPEAKAFQKLGGATVVSNTQSLEKILYDLFSTDELRE
KMGKIAGNYVHSRAGATQKIAGALLPAQKNAPPHRGNTLNAT

Specific function: Essential step in lipopolysaccharides biosynthesis. Acts at transfer of 3-deoxy-D-mono octulonic acid (KDO) from CMP-KDO to a tetraacyldisaccharide 1,4'-bisphosphate precursor of lipid A (lipid IVA). Transfers a single molecule of KDO to lipid IVA [H]

COG id: COG1519

COG function: function code M; 3-deoxy-D-manno-octulosonic-acid transferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Escherichia coli, GI1790064, Length=372, Percent_Identity=26.8817204301075, Blast_Score=121, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR007507 [H]

Pfam domain/function: PF00534 Glycos_transf_1; PF04413 Glycos_transf_N [H]

EC number: 2.-.-.-

Molecular weight: Translated: 50167; Mature: 50167

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRAWLRAYNILFPLFLFSLKILGFFNAKIRATLLGRENLFQRIRAKQKALTHKSGFRLW
CCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCEEE
VHAASVGEFEQARPIVKAIREKDPDAAIILTFLSVSGYEARKNTKEADLVTYLPADTPSN
EEECCCCCHHHHHHHHHHHHCCCCCCEEEHHHHHCCCCHHHCCCCCCCEEEEECCCCCHH
ARKFLDLLQPDALLLMRYDFWPNHLFEAKRRGIYLMLAAAVLQPDSTYNKPIIRGFYQTI
HHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCEEEEEHHHHHCCCCCCCCHHHHHHHHHH
FSLFDQIFTVAEDDAKNFKTLFGLDRVQQAGEPRIDQVIWRSQQQERVAHLKPIYNERLV
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHHHHHCCCEE
LVAGSVWKTDEAHLIPAYQSVREKLLNYPISLILVPHEIGQENLNRMADDLKSKHLSYQF
EEECCCCCCCCCEEEHHHHHHHHHHHHCCEEEEEECHHHCHHHHHHHHHHHHHHHHHHHH
ISRLHSNFNTETVLIIDEIGYLAELYSLAHIAYIGGGFGVHVHNTLEAAVYHLPLIYGPH
HHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHEECCC
FHKSPEAKAFQKLGGATVVSNTQSLEKILYDLFSTDELREKMGKIAGNYVHSRAGATQKI
CCCCCHHHHHHHCCCCEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHH
AGALLPAQKNAPPHRGNTLNAT
HHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQRAWLRAYNILFPLFLFSLKILGFFNAKIRATLLGRENLFQRIRAKQKALTHKSGFRLW
CCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCEEE
VHAASVGEFEQARPIVKAIREKDPDAAIILTFLSVSGYEARKNTKEADLVTYLPADTPSN
EEECCCCCHHHHHHHHHHHHCCCCCCEEEHHHHHCCCCHHHCCCCCCCEEEEECCCCCHH
ARKFLDLLQPDALLLMRYDFWPNHLFEAKRRGIYLMLAAAVLQPDSTYNKPIIRGFYQTI
HHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCEEEEEHHHHHCCCCCCCCHHHHHHHHHH
FSLFDQIFTVAEDDAKNFKTLFGLDRVQQAGEPRIDQVIWRSQQQERVAHLKPIYNERLV
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHHHHHCCCEE
LVAGSVWKTDEAHLIPAYQSVREKLLNYPISLILVPHEIGQENLNRMADDLKSKHLSYQF
EEECCCCCCCCCEEEHHHHHHHHHHHHCCEEEEEECHHHCHHHHHHHHHHHHHHHHHHHH
ISRLHSNFNTETVLIIDEIGYLAELYSLAHIAYIGGGFGVHVHNTLEAAVYHLPLIYGPH
HHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHEECCC
FHKSPEAKAFQKLGGATVVSNTQSLEKILYDLFSTDELREKMGKIAGNYVHSRAGATQKI
CCCCCHHHHHHHCCCCEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHH
AGALLPAQKNAPPHRGNTLNAT
HHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952982; 7542800 [H]