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The map label for this gene is folB [H]

Identifier: 193213976

GI number: 193213976

Start: 302789

End: 303199

Strand: Direct

Name: folB [H]

Synonym: Ctha_0257

Alternate gene names: 193213976

Gene position: 302789-303199 (Clockwise)

Preceding gene: 193213968

Following gene: 193213977

Centisome position: 9.19

GC content: 43.8

Gene sequence:

>411_bases
ATGGACGACTTGCTTAACCGATTCGAGAAAAAACATTGCATTCGGCTCAAAAATGCCATTTTCTATGCGCATCATGGCGT
GAGTGAAGCGGAAAGCGAAGTAGGAAATCGCTATGCAGTTGATGCCGAACTCTACCTTGATTTGAGCCAATCCGGGCAAA
CCGACGACCTTTCGCACACCATCGACTATGGAACGGTTTATTCCCGCATTAAAGATATGGTGCTTTCCAGTCGTTTTTCG
TTGCTCGAATCCATTGCTCATCGCCTTGCCGCATCACTTATGGCGGAATTTACACAATTGGAAAGTGTTCGAATTTTTGT
ACGGAAATATAATCCACCTATTGGTGGAATTTGCGATTATGCCGAAATTGAATATTGGCTTTCGCAAAAAACACCATCGC
AAACGCATTGA

Upstream 100 bases:

>100_bases
TATTCTTCGACAAAAAAATAAAGGTAACCAAGTCTCTTTGTTTTTTCAAACTCTATGCTATTTAGTATTTTTTATTAAAT
GTTGTTAAAATTTCAGCCTT

Downstream 100 bases:

>100_bases
TTTTATTTTTTGAGGAAACGATTTCGCAAGCAATTCAGATTTGTTCATCACACGCATTAGACATCTATTAGAATACATGG
AATTACATTCATCCTCAGAG

Product: dihydroneopterin aldolase

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 136; Mature: 136

Protein sequence:

>136_residues
MDDLLNRFEKKHCIRLKNAIFYAHHGVSEAESEVGNRYAVDAELYLDLSQSGQTDDLSHTIDYGTVYSRIKDMVLSSRFS
LLESIAHRLAASLMAEFTQLESVRIFVRKYNPPIGGICDYAEIEYWLSQKTPSQTH

Sequences:

>Translated_136_residues
MDDLLNRFEKKHCIRLKNAIFYAHHGVSEAESEVGNRYAVDAELYLDLSQSGQTDDLSHTIDYGTVYSRIKDMVLSSRFS
LLESIAHRLAASLMAEFTQLESVRIFVRKYNPPIGGICDYAEIEYWLSQKTPSQTH
>Mature_136_residues
MDDLLNRFEKKHCIRLKNAIFYAHHGVSEAESEVGNRYAVDAELYLDLSQSGQTDDLSHTIDYGTVYSRIKDMVLSSRFS
LLESIAHRLAASLMAEFTQLESVRIFVRKYNPPIGGICDYAEIEYWLSQKTPSQTH

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 15578; Mature: 15578

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDLLNRFEKKHCIRLKNAIFYAHHGVSEAESEVGNRYAVDAELYLDLSQSGQTDDLSHT
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEEECHHEEEEECCCCCCCCCHHH
IDYGTVYSRIKDMVLSSRFSLLESIAHRLAASLMAEFTQLESVRIFVRKYNPPIGGICDY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
AEIEYWLSQKTPSQTH
HHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDDLLNRFEKKHCIRLKNAIFYAHHGVSEAESEVGNRYAVDAELYLDLSQSGQTDDLSHT
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEEECHHEEEEECCCCCCCCCHHH
IDYGTVYSRIKDMVLSSRFSLLESIAHRLAASLMAEFTQLESVRIFVRKYNPPIGGICDY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
AEIEYWLSQKTPSQTH
HHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]