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The map label for this gene is dnaX [H]

Identifier: 193213861

GI number: 193213861

Start: 164911

End: 166122

Strand: Direct

Name: dnaX [H]

Synonym: Ctha_0142

Alternate gene names: 193213861

Gene position: 164911-166122 (Clockwise)

Preceding gene: 193213854

Following gene: 193213862

Centisome position: 5.01

GC content: 47.94

Gene sequence:

>1212_bases
ATGAGCTATCTTGTCATTGCGCGAAAATATCGCCCACAAAAATTTTCCGATATTACCGCGCAAGAACACGTTACCCGAAC
GCTAAGAAATGCCATCCGCACCGGACGCATTGCGCATGGCTATATTTTTTCTGGATCGCGCGGCGTTGGCAAAACAACCG
CTGCAAGAATTTTAGCCAAAGGCCTGAATTGTGAAAAGATTTTAAAGGACGAGGCTTACCGAGAAACCGTCAGCGAGCCG
TGTGGCGAATGCGAAAGTTGCCGCGATTTCGACGCCGGCTCAAGCTTGAATATTTCCGAATTCGACGCCGCTTCCAATAA
CAGCGTTGATGATATTCGCGCGCTTCGCGAAAATGTCCGCTATGCGCCGCAAAAAGGCCGATACAAAGTCTACATCATCG
ATGAATTCCACATGCTTTCAAACGCGGCTTTCAATGCGTTTTTAAAAACACTTGAAGAACCGCCATCTCACGCCGTTTTC
ATTTTTGCGACCACCGAGCTCAACAAAGTGCCGCCAACGATTGCGTCGCGTTGCCAAAAGTTCAACTTCAAACGCATTTC
CGTTTTGGACATTCAAGAGCGATTGGCTGAAATTTGCGCCGCAGAAGCGATCAACATCGATGTCGATTCGCTCACGCTGA
TTGCACGCAAAGCCGACGGCGCGATGCGCGACGCGCAAAGCTTGCTCGATCAAGTCATTTCGTTTTTCCTTTCCACGGAA
AATGAAAAAATCGAGTACACCAATGTTGCCGCACTTTTGGGAGACATCGACGATGAGCATTTTTTTGCCGTCACCGATAG
CATCAAAGAGAAAAATCACGCGAAGGTTTTGGAGCTTTCCCGCTACATTTTTGATAACGGATTCGATACGCTGGACTTTT
TGGCTCGTTTGGTCGAGCATTTTCGCAATTTCTTACTGGTTAAAAATCTGCGCTCCAGCAAATTGATTGAACGCACAGAA
GCGGCCAAAAAGCGCTATGAAGCTGAAGCCGATACGTTCTCTGCGGAAGAACTCATGCGATTCATCGACGTTGTCAATCA
AGCCGAAAAAGATATTCGTTTTTTCCGCGAGCCGCAGCTTCGTTTCGAGCTGGCATTGCTCAAACTGCTGCACGCCGACG
TATCGAGTGGCGATACCGAAGCGCGCCTTTCAGAATTTGACCAGCGCCTGAAGGCCATCGAAACCGAAATAAAAAAAAAG
ACTTCCAGATAA

Upstream 100 bases:

>100_bases
CGGAAAAACGATTTTATTCTTTTGCGCGGCGCAGCCGTTCAGTTTTGCAATTTTATATAATTATATTGAGCCGCTTTTAT
GAAATTTTGAACACAACCGT

Downstream 100 bases:

>100_bases
TTGACGACGAGCCACCGGCGCACGATACACAGCTGCCGGTGGCCGGGCAAACCAACATCACCGCCCTAACACGCATTCCG
AGTTCATCGGAAGTGCTTTC

Product: DNA polymerase III gamma and tau subunits

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MSYLVIARKYRPQKFSDITAQEHVTRTLRNAIRTGRIAHGYIFSGSRGVGKTTAARILAKGLNCEKILKDEAYRETVSEP
CGECESCRDFDAGSSLNISEFDAASNNSVDDIRALRENVRYAPQKGRYKVYIIDEFHMLSNAAFNAFLKTLEEPPSHAVF
IFATTELNKVPPTIASRCQKFNFKRISVLDIQERLAEICAAEAINIDVDSLTLIARKADGAMRDAQSLLDQVISFFLSTE
NEKIEYTNVAALLGDIDDEHFFAVTDSIKEKNHAKVLELSRYIFDNGFDTLDFLARLVEHFRNFLLVKNLRSSKLIERTE
AAKKRYEAEADTFSAEELMRFIDVVNQAEKDIRFFREPQLRFELALLKLLHADVSSGDTEARLSEFDQRLKAIETEIKKK
TSR

Sequences:

>Translated_403_residues
MSYLVIARKYRPQKFSDITAQEHVTRTLRNAIRTGRIAHGYIFSGSRGVGKTTAARILAKGLNCEKILKDEAYRETVSEP
CGECESCRDFDAGSSLNISEFDAASNNSVDDIRALRENVRYAPQKGRYKVYIIDEFHMLSNAAFNAFLKTLEEPPSHAVF
IFATTELNKVPPTIASRCQKFNFKRISVLDIQERLAEICAAEAINIDVDSLTLIARKADGAMRDAQSLLDQVISFFLSTE
NEKIEYTNVAALLGDIDDEHFFAVTDSIKEKNHAKVLELSRYIFDNGFDTLDFLARLVEHFRNFLLVKNLRSSKLIERTE
AAKKRYEAEADTFSAEELMRFIDVVNQAEKDIRFFREPQLRFELALLKLLHADVSSGDTEARLSEFDQRLKAIETEIKKK
TSR
>Mature_402_residues
SYLVIARKYRPQKFSDITAQEHVTRTLRNAIRTGRIAHGYIFSGSRGVGKTTAARILAKGLNCEKILKDEAYRETVSEPC
GECESCRDFDAGSSLNISEFDAASNNSVDDIRALRENVRYAPQKGRYKVYIIDEFHMLSNAAFNAFLKTLEEPPSHAVFI
FATTELNKVPPTIASRCQKFNFKRISVLDIQERLAEICAAEAINIDVDSLTLIARKADGAMRDAQSLLDQVISFFLSTEN
EKIEYTNVAALLGDIDDEHFFAVTDSIKEKNHAKVLELSRYIFDNGFDTLDFLARLVEHFRNFLLVKNLRSSKLIERTEA
AKKRYEAEADTFSAEELMRFIDVVNQAEKDIRFFREPQLRFELALLKLLHADVSSGDTEARLSEFDQRLKAIETEIKKKT
SR

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6677723, Length=315, Percent_Identity=23.8095238095238, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI194306571, Length=313, Percent_Identity=23.6421725239617, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI194306567, Length=313, Percent_Identity=23.6421725239617, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1786676, Length=370, Percent_Identity=38.9189189189189, Blast_Score=275, Evalue=4e-75,
Organism=Caenorhabditis elegans, GI17541988, Length=308, Percent_Identity=24.025974025974, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17554730, Length=277, Percent_Identity=25.6317689530686, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324478, Length=323, Percent_Identity=24.4582043343653, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322528, Length=298, Percent_Identity=23.489932885906, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324039, Length=307, Percent_Identity=21.8241042345277, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17647857, Length=282, Percent_Identity=28.0141843971631, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI18859927, Length=302, Percent_Identity=23.1788079470199, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 45897; Mature: 45765

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYLVIARKYRPQKFSDITAQEHVTRTLRNAIRTGRIAHGYIFSGSRGVGKTTAARILAK
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHH
GLNCEKILKDEAYRETVSEPCGECESCRDFDAGSSLNISEFDAASNNSVDDIRALRENVR
CCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHC
YAPQKGRYKVYIIDEFHMLSNAAFNAFLKTLEEPPSHAVFIFATTELNKVPPTIASRCQK
CCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHH
FNFKRISVLDIQERLAEICAAEAINIDVDSLTLIARKADGAMRDAQSLLDQVISFFLSTE
CCCCEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
NEKIEYTNVAALLGDIDDEHFFAVTDSIKEKNHAKVLELSRYIFDNGFDTLDFLARLVEH
CCCCHHHHHHHHHHCCCCCCEEEEHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
FRNFLLVKNLRSSKLIERTEAAKKRYEAEADTFSAEELMRFIDVVNQAEKDIRFFREPQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHH
RFELALLKLLHADVSSGDTEARLSEFDQRLKAIETEIKKKTSR
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SYLVIARKYRPQKFSDITAQEHVTRTLRNAIRTGRIAHGYIFSGSRGVGKTTAARILAK
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHH
GLNCEKILKDEAYRETVSEPCGECESCRDFDAGSSLNISEFDAASNNSVDDIRALRENVR
CCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHC
YAPQKGRYKVYIIDEFHMLSNAAFNAFLKTLEEPPSHAVFIFATTELNKVPPTIASRCQK
CCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHH
FNFKRISVLDIQERLAEICAAEAINIDVDSLTLIARKADGAMRDAQSLLDQVISFFLSTE
CCCCEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
NEKIEYTNVAALLGDIDDEHFFAVTDSIKEKNHAKVLELSRYIFDNGFDTLDFLARLVEH
CCCCHHHHHHHHHHCCCCCCEEEEHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
FRNFLLVKNLRSSKLIERTEAAKKRYEAEADTFSAEELMRFIDVVNQAEKDIRFFREPQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHH
RFELALLKLLHADVSSGDTEARLSEFDQRLKAIETEIKKKTSR
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2124672; 7584024; 9384377; 2452406; 2468993; 1698458 [H]