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The map label for this gene is trpS [H]

Identifier: 193213678

GI number: 193213678

Start: 2246382

End: 2247389

Strand: Direct

Name: trpS [H]

Synonym: Cpar_2044

Alternate gene names: 193213678

Gene position: 2246382-2247389 (Clockwise)

Preceding gene: 193213675

Following gene: 193213679

Centisome position: 98.13

GC content: 61.9

Gene sequence:

>1008_bases
ATGCGGCCTACCGGCAAACTGCACCTCGGCCACTACTCAGGAGCACTTGAAAACTGGATCGCGCAGCAAAACCTTCTCCA
GCCCGACGGAAGCCGGGCTTACGAGACCTGCTTTCTGATCGCCGACTACCACAGCCTGACCACTTCGCTCGACACCTCGA
TGATCTACGAGCACTCGCTCGACATGCTGGTTGACTGGCTGGCGGCGGGCGTCGATCCGGAGAAAAGCCCGGTGTTCCGT
CAGTCCCAGGTCAAGGAGCACGCCGAGCTGTTCCTGCTCTTTTCGATGCTCATCACCACCGCGCGGCTCGAACGCAACCC
GACGCTCAAGGAGCAGGTGCGCGACCTGAACATGGACTCGCTGGTCTACGGCCACCTCGGCTATCCGGTGCTGCAGGCGG
CGGACATCCTGCTCTACAAGGGCAATGTGGTGCCGGTGGGCGAAGATCAGATTCCGCACGTCGAGATCACCCGCGAGATC
GCCCGCAAGTTCAACAGCCACTACCAGCACCCGGAGCTTGGCGACGTGTTCCCCGAACCCGCGCCGAAGATCACGAAGTT
CGCGCGTCTGGTTGGTCTGGACGGCAAGGCGAAGATGTCGAAATCGCTTGGCAACACGATTTTGCTCTCGGACGGCCCTG
ACGAGGTGCTCGCGAAGATGCGCCCCGCCGTGACCGACACGCAGAAGGTACGCCGCAACGATCCGGGCCGCCCGGAAGTG
TGCCTGGTTTACAGCTACCACCAGAAGTTCACTGGCGAGGCGCAGCTGGCCGAAATCGAGGCGGGGTGCCGCTCCGGAGC
GCTCGGCTGCGTCGATTGCAAAAAGATGTGCGCGGCAAACATCTCGGCGGAGCTGGCTCCGATCCTCGAACGGCGCAAGC
ACTACGAAGAGCGCCCGGAGATGGTCAAGGAGATTCTGCACGAAGGCGAAAGGAAAGCGCGAAAGATCGCCGGAGAAACC
ATGAAAGAGGTGAGAGAGGCGATGAGCCTCGGGGAGAGCAACGCATGA

Upstream 100 bases:

>100_bases
TTCAAGCCGGGGGCATTGAGCGCCACCATAACTATAGAGATTCCCTGCAAAACAGGAGCAACAAACCCGACCCATGTCGA
CACAAAGGATTTTAAGCGGG

Downstream 100 bases:

>100_bases
AGATGACACCTGCAAACAACAGTCCGAAAGCCTTCATTTTCGATATGGATGGCGTGCTGGTCGATAACATGAGAATGCAC
GCCCAGTCGTGGGTCGATCT

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MRPTGKLHLGHYSGALENWIAQQNLLQPDGSRAYETCFLIADYHSLTTSLDTSMIYEHSLDMLVDWLAAGVDPEKSPVFR
QSQVKEHAELFLLFSMLITTARLERNPTLKEQVRDLNMDSLVYGHLGYPVLQAADILLYKGNVVPVGEDQIPHVEITREI
ARKFNSHYQHPELGDVFPEPAPKITKFARLVGLDGKAKMSKSLGNTILLSDGPDEVLAKMRPAVTDTQKVRRNDPGRPEV
CLVYSYHQKFTGEAQLAEIEAGCRSGALGCVDCKKMCAANISAELAPILERRKHYEERPEMVKEILHEGERKARKIAGET
MKEVREAMSLGESNA

Sequences:

>Translated_335_residues
MRPTGKLHLGHYSGALENWIAQQNLLQPDGSRAYETCFLIADYHSLTTSLDTSMIYEHSLDMLVDWLAAGVDPEKSPVFR
QSQVKEHAELFLLFSMLITTARLERNPTLKEQVRDLNMDSLVYGHLGYPVLQAADILLYKGNVVPVGEDQIPHVEITREI
ARKFNSHYQHPELGDVFPEPAPKITKFARLVGLDGKAKMSKSLGNTILLSDGPDEVLAKMRPAVTDTQKVRRNDPGRPEV
CLVYSYHQKFTGEAQLAEIEAGCRSGALGCVDCKKMCAANISAELAPILERRKHYEERPEMVKEILHEGERKARKIAGET
MKEVREAMSLGESNA
>Mature_335_residues
MRPTGKLHLGHYSGALENWIAQQNLLQPDGSRAYETCFLIADYHSLTTSLDTSMIYEHSLDMLVDWLAAGVDPEKSPVFR
QSQVKEHAELFLLFSMLITTARLERNPTLKEQVRDLNMDSLVYGHLGYPVLQAADILLYKGNVVPVGEDQIPHVEITREI
ARKFNSHYQHPELGDVFPEPAPKITKFARLVGLDGKAKMSKSLGNTILLSDGPDEVLAKMRPAVTDTQKVRRNDPGRPEV
CLVYSYHQKFTGEAQLAEIEAGCRSGALGCVDCKKMCAANISAELAPILERRKHYEERPEMVKEILHEGERKARKIAGET
MKEVREAMSLGESNA

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=332, Percent_Identity=35.8433734939759, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI41352700, Length=181, Percent_Identity=41.9889502762431, Blast_Score=137, Evalue=2e-32,
Organism=Escherichia coli, GI1789786, Length=337, Percent_Identity=33.5311572700297, Blast_Score=162, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI71982800, Length=338, Percent_Identity=29.8816568047337, Blast_Score=133, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI71982793, Length=338, Percent_Identity=29.8816568047337, Blast_Score=131, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6320474, Length=361, Percent_Identity=32.6869806094183, Blast_Score=148, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24666151, Length=341, Percent_Identity=35.7771260997067, Blast_Score=173, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37525; Mature: 37525

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPTGKLHLGHYSGALENWIAQQNLLQPDGSRAYETCFLIADYHSLTTSLDTSMIYEHSL
CCCCCCEEECHHHHHHHHHHHHHHCCCCCCCHHHHHEEEEEHHHHHHHHHHHHHHHHHHH
DMLVDWLAAGVDPEKSPVFRQSQVKEHAELFLLFSMLITTARLERNPTLKEQVRDLNMDS
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHH
LVYGHLGYPVLQAADILLYKGNVVPVGEDQIPHVEITREIARKFNSHYQHPELGDVFPEP
HHHHHCCCHHHHHHHEEEECCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
APKITKFARLVGLDGKAKMSKSLGNTILLSDGPDEVLAKMRPAVTDTQKVRRNDPGRPEV
CHHHHHHHHHHCCCCHHHHHHHCCCEEEECCCHHHHHHHHCCCCCHHHHHHCCCCCCCCE
CLVYSYHQKFTGEAQLAEIEAGCRSGALGCVDCKKMCAANISAELAPILERRKHYEERPE
EEEEEHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
MVKEILHEGERKARKIAGETMKEVREAMSLGESNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRPTGKLHLGHYSGALENWIAQQNLLQPDGSRAYETCFLIADYHSLTTSLDTSMIYEHSL
CCCCCCEEECHHHHHHHHHHHHHHCCCCCCCHHHHHEEEEEHHHHHHHHHHHHHHHHHHH
DMLVDWLAAGVDPEKSPVFRQSQVKEHAELFLLFSMLITTARLERNPTLKEQVRDLNMDS
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHH
LVYGHLGYPVLQAADILLYKGNVVPVGEDQIPHVEITREIARKFNSHYQHPELGDVFPEP
HHHHHCCCHHHHHHHEEEECCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
APKITKFARLVGLDGKAKMSKSLGNTILLSDGPDEVLAKMRPAVTDTQKVRRNDPGRPEV
CHHHHHHHHHHCCCCHHHHHHHCCCEEEECCCHHHHHHHHCCCCCHHHHHHCCCCCCCCE
CLVYSYHQKFTGEAQLAEIEAGCRSGALGCVDCKKMCAANISAELAPILERRKHYEERPE
EEEEEHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
MVKEILHEGERKARKIAGETMKEVREAMSLGESNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]