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The map label for this gene is fur [H]

Identifier: 193213196

GI number: 193213196

Start: 1697807

End: 1698340

Strand: Direct

Name: fur [H]

Synonym: Cpar_1551

Alternate gene names: 193213196

Gene position: 1697807-1698340 (Clockwise)

Preceding gene: 193213191

Following gene: 193213197

Centisome position: 74.16

GC content: 58.24

Gene sequence:

>534_bases
TTGGAAAAATTGAAAACACGAAATACTGACAGCAAGAACATCGTGAAACAAACGGGCAGCGACACGATCGCGAAGGTCGA
AGCGCTTTTCAAATCGTACATGAAGGAGGAGGGGCTCCGGTGCACCCAGGAGCGCCTGAGCGTGCTGCGGGAAATCTACC
GCTCCAACACGCACCTCGACGCCGACGAGCTGTTTGTCCGGCTTCGCGAGCAAGGCGTGGGCATCTCGCGCGCCACGGTT
TATCACACCCTCGATCTGCTGTTCCGGTACAACCTCGTCACCAAGATCGACCTCGGCCACAAGCACACGCACTACGAAAA
ATCGTGGGGTGTCGCCGACCACCTGCACATCATCTGCCTCAAGTGCGGCAAGGTTTCGGAGGCCACGAGCACGGAACTTG
CCGGCATGATGGAAAAGCTCTGCACCGAGCACGGATACTCGCTCGGCAGCTTCAGCCTGCAGCTCTTCGGCGAGTGCATT
GACAAGGAGGCCTGCGTCCGGAGGGTCGACGAGAAACACAACGAGAACGCCTGA

Upstream 100 bases:

>100_bases
AATAGTCGTCTAATGTACGGTTTTCAGCGCTCTTTTCCGTCCGGCTCTTCCCGCTCCGCCGCCTTCATGGTTCACAGGGA
ATTCGCAGAAAAACAATACA

Downstream 100 bases:

>100_bases
ACTCACGGACACCATGCCCTGGCTCTACCTCATCCTCGCCATCGTCGCCGAAGTCTCCGGCACCACCAGCATGAAGCTCT
CGGAGGGCTTCACCAAACCG

Product: Fur family ferric uptake regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MEKLKTRNTDSKNIVKQTGSDTIAKVEALFKSYMKEEGLRCTQERLSVLREIYRSNTHLDADELFVRLREQGVGISRATV
YHTLDLLFRYNLVTKIDLGHKHTHYEKSWGVADHLHIICLKCGKVSEATSTELAGMMEKLCTEHGYSLGSFSLQLFGECI
DKEACVRRVDEKHNENA

Sequences:

>Translated_177_residues
MEKLKTRNTDSKNIVKQTGSDTIAKVEALFKSYMKEEGLRCTQERLSVLREIYRSNTHLDADELFVRLREQGVGISRATV
YHTLDLLFRYNLVTKIDLGHKHTHYEKSWGVADHLHIICLKCGKVSEATSTELAGMMEKLCTEHGYSLGSFSLQLFGECI
DKEACVRRVDEKHNENA
>Mature_177_residues
MEKLKTRNTDSKNIVKQTGSDTIAKVEALFKSYMKEEGLRCTQERLSVLREIYRSNTHLDADELFVRLREQGVGISRATV
YHTLDLLFRYNLVTKIDLGHKHTHYEKSWGVADHLHIICLKCGKVSEATSTELAGMMEKLCTEHGYSLGSFSLQLFGECI
DKEACVRRVDEKHNENA

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=127, Percent_Identity=32.2834645669291, Blast_Score=64, Evalue=4e-12,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 20251; Mature: 20251

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLKTRNTDSKNIVKQTGSDTIAKVEALFKSYMKEEGLRCTQERLSVLREIYRSNTHLD
CCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
ADELFVRLREQGVGISRATVYHTLDLLFRYNLVTKIDLGHKHTHYEKSWGVADHLHIICL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHCCHHHHHHHHHH
KCGKVSEATSTELAGMMEKLCTEHGYSLGSFSLQLFGECIDKEACVRRVDEKHNENA
HCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEKLKTRNTDSKNIVKQTGSDTIAKVEALFKSYMKEEGLRCTQERLSVLREIYRSNTHLD
CCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
ADELFVRLREQGVGISRATVYHTLDLLFRYNLVTKIDLGHKHTHYEKSWGVADHLHIICL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHCCHHHHHHHHHH
KCGKVSEATSTELAGMMEKLCTEHGYSLGSFSLQLFGECIDKEACVRRVDEKHNENA
HCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083178 [H]