Click here to switch to the map view.

The map label for this gene is dnaX [H]

Identifier: 193213177

GI number: 193213177

Start: 1677223

End: 1678392

Strand: Direct

Name: dnaX [H]

Synonym: Cpar_1532

Alternate gene names: 193213177

Gene position: 1677223-1678392 (Clockwise)

Preceding gene: 193213176

Following gene: 193213178

Centisome position: 73.27

GC content: 60.17

Gene sequence:

>1170_bases
ATGAGCTGGAATTCTATCGTTGGACATGAAAATCAGATCCGGGTGCTGAAAACAGCGCTCGGATCGAACCGTCTGGCTCA
TGCCTACCTCTTTGCCGGGCCTGAAGGATCGGGAAAGGAAACCGTGGCGTTCGAACTGGCGAAGATTCTGAATTGCCGCA
ACACAAACCTCCTGCCTGATGAAGGCTCGTGCGGCGAGTGCGAAAGCTGCCGCCAGGCCGACAAGCTCATGCACCCCAAC
ATCGAGTACCTCTTCCCCGTCGAAGCAGCGCTACTCGAAACCATCGATCCGTCAAAAAAGGAGAACAAAAAGGTTGCCGA
AGCCAGGGAACGCTACGAAGCGTTGCTCGACGAAAAGCGGAAAAACCCGTTCTTTACGCCCACGATGGAACGCTCGATGG
GCATTCTGACCGAGCAGGTGGTGATGTTGCAACAGAAAGCCTCGCTCGCCCCGCGCGACGGCGGCAAAAAGGTGTTCATC
ATCTCGCAGGCCGACCGGCTCCACCCGACAGCAGCCAACAAGCTGCTCAAGCTGCTCGAAGAGCCACCGGCACACGTAGT
GTTCGTTCTGGTGAGTTCGCGCCCCGAATCGGTGCTGCCCACCATCCGCTCGCGCTGCCAGCTTCTCACCTTCGCCCGCC
CGCGCCCGGCGGAGATCGAAGCCTGGATCGCCCGCCGCGCCCCGCAGCTCGACGAAACCGAACGCCGCTTCATCGTCAGC
CTCTCGCGCGGGAACCTCTCCAGCGCGCTCGAACTGATCGAAGCCGAAACCGGCGAAGGAGCAGCCCCGGCGGTGGTCGG
CATCCGCAACAAAGCCATCGACTACCTCCGCAATATCCTCGTGCCCGCCAAATTCCACGAAGCCATCGGCACGTGCGAAG
AGCTTGCCAAAAGCTCCACGCGCACCGAACAGCTCATCTTCCTCGACGCGCTCCTGCTCTTCTTCCAGGACGTCACCCGC
CGCAGCATCGACCACAACTTCCCGGAACTCAACAATCCCGACATCGCGGAAAACACCGACCGCTTCGTCAAAGCCTTCCC
CAACCGCGACCTCTACCGCGCCTCGACCATCATCGAAGAGGCAATGCGCGCCATCAACCGCAACGCCAGCGTGATTCTCG
TAATGGCCGCCATGACCGCCGATTTAAGGGAGATTTTGCTGGGGAAGTGA

Upstream 100 bases:

>100_bases
CGCGGCCCGGTCACCGAAGCGTTGCAGCACGAGTACCTCAAAATCGTCCACTCCGGAGAGGATCCGTTCAACTGGCTGAC
CTTTATTTGACCGGAAAGGC

Downstream 100 bases:

>100_bases
GGGGGAAAATAATCTATATGACTCACATGTATTCTTAAGTATCTCGCCGAACAGTTATCGTTCAAGCAAGAACTTAAGCA
TACACTTAAATTTCACAGGA

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MSWNSIVGHENQIRVLKTALGSNRLAHAYLFAGPEGSGKETVAFELAKILNCRNTNLLPDEGSCGECESCRQADKLMHPN
IEYLFPVEAALLETIDPSKKENKKVAEARERYEALLDEKRKNPFFTPTMERSMGILTEQVVMLQQKASLAPRDGGKKVFI
ISQADRLHPTAANKLLKLLEEPPAHVVFVLVSSRPESVLPTIRSRCQLLTFARPRPAEIEAWIARRAPQLDETERRFIVS
LSRGNLSSALELIEAETGEGAAPAVVGIRNKAIDYLRNILVPAKFHEAIGTCEELAKSSTRTEQLIFLDALLLFFQDVTR
RSIDHNFPELNNPDIAENTDRFVKAFPNRDLYRASTIIEEAMRAINRNASVILVMAAMTADLREILLGK

Sequences:

>Translated_389_residues
MSWNSIVGHENQIRVLKTALGSNRLAHAYLFAGPEGSGKETVAFELAKILNCRNTNLLPDEGSCGECESCRQADKLMHPN
IEYLFPVEAALLETIDPSKKENKKVAEARERYEALLDEKRKNPFFTPTMERSMGILTEQVVMLQQKASLAPRDGGKKVFI
ISQADRLHPTAANKLLKLLEEPPAHVVFVLVSSRPESVLPTIRSRCQLLTFARPRPAEIEAWIARRAPQLDETERRFIVS
LSRGNLSSALELIEAETGEGAAPAVVGIRNKAIDYLRNILVPAKFHEAIGTCEELAKSSTRTEQLIFLDALLLFFQDVTR
RSIDHNFPELNNPDIAENTDRFVKAFPNRDLYRASTIIEEAMRAINRNASVILVMAAMTADLREILLGK
>Mature_388_residues
SWNSIVGHENQIRVLKTALGSNRLAHAYLFAGPEGSGKETVAFELAKILNCRNTNLLPDEGSCGECESCRQADKLMHPNI
EYLFPVEAALLETIDPSKKENKKVAEARERYEALLDEKRKNPFFTPTMERSMGILTEQVVMLQQKASLAPRDGGKKVFII
SQADRLHPTAANKLLKLLEEPPAHVVFVLVSSRPESVLPTIRSRCQLLTFARPRPAEIEAWIARRAPQLDETERRFIVSL
SRGNLSSALELIEAETGEGAAPAVVGIRNKAIDYLRNILVPAKFHEAIGTCEELAKSSTRTEQLIFLDALLLFFQDVTRR
SIDHNFPELNNPDIAENTDRFVKAFPNRDLYRASTIIEEAMRAINRNASVILVMAAMTADLREILLGK

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787341, Length=238, Percent_Identity=27.3109243697479, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 43527; Mature: 43395

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWNSIVGHENQIRVLKTALGSNRLAHAYLFAGPEGSGKETVAFELAKILNCRNTNLLPD
CCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCC
EGSCGECESCRQADKLMHPNIEYLFPVEAALLETIDPSKKENKKVAEARERYEALLDEKR
CCCCCCHHHHHHHHHHCCCCCCEEECHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHC
KNPFFTPTMERSMGILTEQVVMLQQKASLAPRDGGKKVFIISQADRLHPTAANKLLKLLE
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHH
EPPAHVVFVLVSSRPESVLPTIRSRCQLLTFARPRPAEIEAWIARRAPQLDETERRFIVS
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCEEEEE
LSRGNLSSALELIEAETGEGAAPAVVGIRNKAIDYLRNILVPAKFHEAIGTCEELAKSST
ECCCCHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
RTEQLIFLDALLLFFQDVTRRSIDHNFPELNNPDIAENTDRFVKAFPNRDLYRASTIIEE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHH
AMRAINRNASVILVMAAMTADLREILLGK
HHHHHCCCCCEEEEHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SWNSIVGHENQIRVLKTALGSNRLAHAYLFAGPEGSGKETVAFELAKILNCRNTNLLPD
CCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCC
EGSCGECESCRQADKLMHPNIEYLFPVEAALLETIDPSKKENKKVAEARERYEALLDEKR
CCCCCCHHHHHHHHHHCCCCCCEEECHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHC
KNPFFTPTMERSMGILTEQVVMLQQKASLAPRDGGKKVFIISQADRLHPTAANKLLKLLE
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHH
EPPAHVVFVLVSSRPESVLPTIRSRCQLLTFARPRPAEIEAWIARRAPQLDETERRFIVS
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCEEEEE
LSRGNLSSALELIEAETGEGAAPAVVGIRNKAIDYLRNILVPAKFHEAIGTCEELAKSST
ECCCCHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
RTEQLIFLDALLLFFQDVTRRSIDHNFPELNNPDIAENTDRFVKAFPNRDLYRASTIIEE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHH
AMRAINRNASVILVMAAMTADLREILLGK
HHHHHCCCCCEEEEHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]