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The map label for this gene is kefC [C]

Identifier: 193212743

GI number: 193212743

Start: 1200599

End: 1202842

Strand: Direct

Name: kefC [C]

Synonym: Cpar_1088

Alternate gene names: 193212743

Gene position: 1200599-1202842 (Clockwise)

Preceding gene: 193212741

Following gene: 193212744

Centisome position: 52.45

GC content: 53.97

Gene sequence:

>2244_bases
ATGGAGCATTACTACGTTGAACTTCTTCAGGAATTTCAGTTACCGCTGACCAATCCGGTGCTGATTTTTTCGCTCGTGTT
GTTCATCATTTTGCTCTCGCCTATCGTCCTCAAGCGTTTTAATATTCCGGGAACGGTCGGTCTGATTCTCTCCGGCGTGC
TGATTGGCCCCTATGCCCTGAATCTGCTTGAAAAAAGCTCGGCGGTGGATCTGTTTTCGACCATCGGCCTGCTTTACATC
ATGTTCATTGCCGGGGCAGAACTTCAGGTCAACGAGCTGAAGCGAAACCGCAATCAAAGCCTCCTGTTTGGCCTCCTGAC
CCTCATCGTGCCTATCGTTGCGGTTTATCCGGTGTGCCGCTATTTACTCAATTACAATGTGAGTGCGAGCCTGCTTACGG
CCAGCATGCTTGCGACCCATACGCTGGTAGCTTATCCGATCGTCAACCGCATGGGCATTGCAAAAAACCAGGCCGTGCCC
ATAACGGTGGCCGGCACGATTCTGACCGACACCGCTGTCCTGCTGCTGCTTGCAGTCATCATCGGCTACAGTCAGGGCAA
TCTCACTCAGGAGTTCTGGCTCCACCTCGCCATTTCGCTCACGATTTTCACGATGATCGTCTTCATCGTACTGCCGTTTA
TCGCGCGTTGGTTCTTTACCAAGCTCGAAAACGAGAAGCATGCGCACTACATCTTTGTGCTTTCGGCCGTCTTTTTCTCG
GCCTTCCTCTCCAGAGTCGCCGGGCTTGAACCGATTGTCGGAGCATTCGCTGCGGGCCTGGCGCTCAACCGGCTCATTCC
GAACTCTTCAGCTCTGATGAACCGCATCGAATTTATCGGCAATTCCCTGTTCATCCCGTTTTTCCTGATCAGCGTGGGAA
TGCTGGTGGATCTCAGGGTGATCCTGAGCGGCCCGATGACCCTCATCATCGCAGCGTTGCTGACGGTGGTGGCGCTTGCA
GGAAAATGGCTCCCGGCATGGGTGACCCAGAAGCTGTTCAAGTTGTCGGCAGCGCAACGGCAGCTGATCTTCGGATTGAG
CAGCTCCCGGGCGGCGGCCACCATCGCGATCGTGCTGGTCGGCTATCAGGCTCGTATTCTCGACCTGAACATTCTGAACG
CTACCATCATTCTGATTCTGGTGACGTGCATCGTAGGCTCAATGGTCACCGAAAAAGCCGCCAAAGAGATCGTCGTCGAG
GAGAGCCAGGCAAGTCCGGTAGATGAGAGTGATGAGGCGAGCTTCTCCGAGCAGATTTTGCTACCGATCGCCGAAGGGTT
GCCCTCTGAACGGGTACTTGAATTTGCGGTGCTCATCAGGGAGAAACGCTCGGCCAAGCCGCTGATTCTGCTGAGTGTGG
TGCCCAACGACCACGAGGCTGAGTTGAACATGAAAAAATCCAAAAAGGCGCTGGAGCCGATGATCAACTACGCGGCTTCG
TTCGATACGAAACTCGATATCGTGGCCACAATCGACTATAACGTCAGCAGCGGCATCAGTCGTATGGCAAGAGAGCTGCA
AGCCGACCTGGTGGTGTATGGCTGGCCACTGCACAGAGGTTTCATTGCCCGGCTGATCAACGATTCGGCAGAAAGCATCG
TCAACTGCACCAGCAAAACCACCATCATCTGCCAAATCACCCAACCGCTCGCTTTGCATCGCCGGTTGGTGGTGATCATT
CCGCCGCTGGCCGAAATGGAGAAAGGCTTCGAGCAGTGGGTCGCGAAAATGACGCTGCTGTCACTGGAGCTGAGCATACC
GATGGAACTCCACTGCAACAGCAAAACCCACGCCGCCGTGCTCGACAGCTTCGACTCGATGCAGTCGGCGCCCAAGTTGC
TTTTCGAGCCGATGAAAAATGCACGCGACTGGGAAAACCTGTCCAGACAACGCAAGCGCTTCAAGGATGACGACATCATC
GTGCTGGTCAGCGCCCGAAAGGATTCGCTTTCATACAAACCCTATTTCGACCAGAGCCCGGAACAGCTCGAAAAGCATTT
CGGAGGCATCAGCAAAATCATGATCTACCCGGCCAGCTACGGTGCAGCCAATATTGCTGAAGGGTATGTTGACGTGGTCG
TACCGGAACCGATTCGCATCGGCGCTTCGGCAATTCGGAAAGTCGGAAACGAGCTCGGTCTGTTCCTGAAAAAAAATCAG
CAGCAGATCAGAAAAAAGATTCGCGATAAACGTCAAAACCAGCAAAAAACGCAGGATACCACAGAAAAGGGCGACAAGCC
GTAA

Upstream 100 bases:

>100_bases
TCCCCCGCTTTGTCCACCCATTACCTGTCAGCGCATTCGGATAAATTGTTTAAATTTCAGCGATACCACGATCCGAAAAC
CTTGAAGCGGACTCGCACGC

Downstream 100 bases:

>100_bases
GGTTATTTCACAAAATGGTCGTATCGTTCAATTTATATGTCAGGACAAAGGCACTGAACACCCATTACCGGTATATGCGA
GCAGAACATCTCTTCCGGCC

Product: sodium/hydrogen exchanger

Products: Proton [Cytoplasm]; K (I) [Periplasm] [C]

Alternate protein names: MjNapA [H]

Number of amino acids: Translated: 747; Mature: 747

Protein sequence:

>747_residues
MEHYYVELLQEFQLPLTNPVLIFSLVLFIILLSPIVLKRFNIPGTVGLILSGVLIGPYALNLLEKSSAVDLFSTIGLLYI
MFIAGAELQVNELKRNRNQSLLFGLLTLIVPIVAVYPVCRYLLNYNVSASLLTASMLATHTLVAYPIVNRMGIAKNQAVP
ITVAGTILTDTAVLLLLAVIIGYSQGNLTQEFWLHLAISLTIFTMIVFIVLPFIARWFFTKLENEKHAHYIFVLSAVFFS
AFLSRVAGLEPIVGAFAAGLALNRLIPNSSALMNRIEFIGNSLFIPFFLISVGMLVDLRVILSGPMTLIIAALLTVVALA
GKWLPAWVTQKLFKLSAAQRQLIFGLSSSRAAATIAIVLVGYQARILDLNILNATIILILVTCIVGSMVTEKAAKEIVVE
ESQASPVDESDEASFSEQILLPIAEGLPSERVLEFAVLIREKRSAKPLILLSVVPNDHEAELNMKKSKKALEPMINYAAS
FDTKLDIVATIDYNVSSGISRMARELQADLVVYGWPLHRGFIARLINDSAESIVNCTSKTTIICQITQPLALHRRLVVII
PPLAEMEKGFEQWVAKMTLLSLELSIPMELHCNSKTHAAVLDSFDSMQSAPKLLFEPMKNARDWENLSRQRKRFKDDDII
VLVSARKDSLSYKPYFDQSPEQLEKHFGGISKIMIYPASYGAANIAEGYVDVVVPEPIRIGASAIRKVGNELGLFLKKNQ
QQIRKKIRDKRQNQQKTQDTTEKGDKP

Sequences:

>Translated_747_residues
MEHYYVELLQEFQLPLTNPVLIFSLVLFIILLSPIVLKRFNIPGTVGLILSGVLIGPYALNLLEKSSAVDLFSTIGLLYI
MFIAGAELQVNELKRNRNQSLLFGLLTLIVPIVAVYPVCRYLLNYNVSASLLTASMLATHTLVAYPIVNRMGIAKNQAVP
ITVAGTILTDTAVLLLLAVIIGYSQGNLTQEFWLHLAISLTIFTMIVFIVLPFIARWFFTKLENEKHAHYIFVLSAVFFS
AFLSRVAGLEPIVGAFAAGLALNRLIPNSSALMNRIEFIGNSLFIPFFLISVGMLVDLRVILSGPMTLIIAALLTVVALA
GKWLPAWVTQKLFKLSAAQRQLIFGLSSSRAAATIAIVLVGYQARILDLNILNATIILILVTCIVGSMVTEKAAKEIVVE
ESQASPVDESDEASFSEQILLPIAEGLPSERVLEFAVLIREKRSAKPLILLSVVPNDHEAELNMKKSKKALEPMINYAAS
FDTKLDIVATIDYNVSSGISRMARELQADLVVYGWPLHRGFIARLINDSAESIVNCTSKTTIICQITQPLALHRRLVVII
PPLAEMEKGFEQWVAKMTLLSLELSIPMELHCNSKTHAAVLDSFDSMQSAPKLLFEPMKNARDWENLSRQRKRFKDDDII
VLVSARKDSLSYKPYFDQSPEQLEKHFGGISKIMIYPASYGAANIAEGYVDVVVPEPIRIGASAIRKVGNELGLFLKKNQ
QQIRKKIRDKRQNQQKTQDTTEKGDKP
>Mature_747_residues
MEHYYVELLQEFQLPLTNPVLIFSLVLFIILLSPIVLKRFNIPGTVGLILSGVLIGPYALNLLEKSSAVDLFSTIGLLYI
MFIAGAELQVNELKRNRNQSLLFGLLTLIVPIVAVYPVCRYLLNYNVSASLLTASMLATHTLVAYPIVNRMGIAKNQAVP
ITVAGTILTDTAVLLLLAVIIGYSQGNLTQEFWLHLAISLTIFTMIVFIVLPFIARWFFTKLENEKHAHYIFVLSAVFFS
AFLSRVAGLEPIVGAFAAGLALNRLIPNSSALMNRIEFIGNSLFIPFFLISVGMLVDLRVILSGPMTLIIAALLTVVALA
GKWLPAWVTQKLFKLSAAQRQLIFGLSSSRAAATIAIVLVGYQARILDLNILNATIILILVTCIVGSMVTEKAAKEIVVE
ESQASPVDESDEASFSEQILLPIAEGLPSERVLEFAVLIREKRSAKPLILLSVVPNDHEAELNMKKSKKALEPMINYAAS
FDTKLDIVATIDYNVSSGISRMARELQADLVVYGWPLHRGFIARLINDSAESIVNCTSKTTIICQITQPLALHRRLVVII
PPLAEMEKGFEQWVAKMTLLSLELSIPMELHCNSKTHAAVLDSFDSMQSAPKLLFEPMKNARDWENLSRQRKRFKDDDII
VLVSARKDSLSYKPYFDQSPEQLEKHFGGISKIMIYPASYGAANIAEGYVDVVVPEPIRIGASAIRKVGNELGLFLKKNQ
QQIRKKIRDKRQNQQKTQDTTEKGDKP

Specific function: This is probably a Na(+)/H(+) antiporter [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Escherichia coli, GI1786232, Length=391, Percent_Identity=25.5754475703325, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322367, Length=458, Percent_Identity=24.8908296943231, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 82861; Mature: 82861

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Cytoplasm] = Proton [Cytoplasm] + K (I) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]