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The map label for this gene is hsdR [H]

Identifier: 193212614

GI number: 193212614

Start: 1059482

End: 1061839

Strand: Direct

Name: hsdR [H]

Synonym: Cpar_0959

Alternate gene names: 193212614

Gene position: 1059482-1061839 (Clockwise)

Preceding gene: 193212608

Following gene: 193212615

Centisome position: 46.28

GC content: 54.11

Gene sequence:

>2358_bases
ATGGATAAAAAGCAACTCTCCGAGCGGGACATCTGTACCAAATTTATCACGCCATCACTTGAGCAAGTGGGGTGGGACAT
CGCTACCCAGGTGCGCGAGGAGTTTCCGTTGACCAATGGTCGCATCATCGTGCGGGGCAGCGTGCATACTCGCGGCAGCC
GCAAGCGCGCGGATTACGTGCTGTTTTACAAGCCCAACATTCCCATTGCCGTCATCGAAGCCAAGGATAACAAGCATTCG
CTGGGCGATGGAATGCAGCAGGCTCTGGGCTATGCCGATTTGCTTCAAGTTCCTTTCGTCTTCAGCTCTAACGGTGACGG
ATTTCTGTTCCATAACAAACTTGCCCCTGACGGCATCATTGAGCGCGAACTTGCCTTGCATGAATTTCCTTCCGCCGAAA
CGCTCTGGCAGTGGTGGGCAGCGCACCGAGGACTTGACGATCGACAGAACAACCTCGTAACTCAGGACTATTTCAGCGAC
GGTTCCGGCAAGACGCCCCGATACTACCAGTTACTCGCGATCAACAAAACTGTCGAGGCCATTGCAGGCGGGCAGAACCG
CATCCTCTTGGTCATGGCGACCGGAACTGGCAAGACCTTCACCGCTTTTCAGATCATCTGGCGGCTTTGGAAATCGAAAG
CGAAAAAGCGCATCCTTTTTCTTGCTGACCGCAACATTCTGGTCGATCAGGCCATTACCAACGACTTCAAGCCCTTCGGA
TCGGCAATGACCAAGATTCAGAAGCGGCAGGCCGACAAGTCGTATGAAATCTATCTTTCCCTTTATCAAGCAGTTACGGG
CAATGAAGAAGAGAAGAATATCTACAAACAGTTCAGTCCCGACTTTTTCGATCTGGTCATTATCGACGAGTGCCATCGGG
GTAGCGCCGCTGAGGATTCGGCATGGCGCGAGATTCTGGAATACTTCAATTCGGCTACGCAGATCGGCCTGACTGCTACG
CCGAAAGAGACCAAAGAGGTCTCGAACATCGACTATTTCGGCGAACCGATTTACACCTATTCTCTCAAGCAGGGCATCAA
TGACGGCTTTCTGGCGCCGTATAAGGTGGTGCGTATCGACATCGACAAAGACCTCGAAGGCTGGCGGCCCGACAAGGGAA
TGCTCGACAAGTACGGCAACGAAATCGAAGATCGCATTTACAACCAGCGGGATTTCGACCGTAGCCTCGTGCTGGAAAAG
CGCACTGAACTGGTGGCCAGGAAGGTGAGCGATTTTCTGCGCCGTACCAATCGCTTTGACAAAACCATCATCTTCTGCGA
GAACATCGAACACGCTGAGCGTATGAGGCAGGCGTTGGTGAACGAAAACAGCGACCTGGCCTCGAAGCACGACAAGTACG
TCGTGCGCATCACCGGCGATAACGAAGAGGGCAAGGCCGAACTCGACAACTTCATCTTTCCCGAAAAAACCTTTCCGGTC
ATCGCCACCACCTCAAAACTCATGACCACCGGTGTCGATGCACAGACCTGCAAGCTCATCGTGCTCGACCAGCGCATCCA
GTCGATGACAGAGTTCAAGCAGATTATCGGGCGCGGCACGCGCATCAACGAGGAGTTTGGCAAGTTTTATTTCACCATCA
TCGATTTCAAAAAGGCGACCGAGCTGTTTGCCGACCCCGATTTCGACGGTGATCCAGTGCAGATATATGAACCACAAGCC
GGCGACTCTCCCTTACCTCCCGATATTTCGGGCGGAGAGCCCTATCCGGAAGGTCAAGAGGATCAGGATTGGCCCGATTT
ACAGGATAAGCCTGTTACTGGCGGAGTGCGCCGCTATGTCGTCGATAATGTTGAAGTGCGGGTGGTTGCCGAGCGGGTGC
AGTACTTCGACGCCAATGGCAAGCTCATCACTGAATCGCTCCGCGACTACACGCGCAAGGCGCTTGCCGGGGAGTTTGAA
TCGCTCTATGACTTCCTCAACCGCTGGAACAGCGCCGAACAGAAGCAGGCGATCATCGACGAGTTGGCCGAACACGGCAT
CTTTTTCGAGGCGCTTGCCGACGAGATCGGGCGCAAGTCCGGTAAGTCCTTCGATCCGTTCGATCTCATTTGCCATGTAG
CCTGGGACATGCCGCCGCTCAGCCGGAAGGAGCGAGCCGAGCAGGTCAAAAAGCGAAACTATTTCACGAAGTATGGTGAG
GAGGCCCGCAAGGTGCTCGAAGCGCTTCTTGACAAGTATGCCGACGAAGGCATCGGCCACGTCGAGGAGACGCAAATCCT
TACCATTTCGCCGTTTACCGAAATTGGTACGCCAATGGAGATCGTGCGCTTTTTCGGCGGAGTGGATGGGTACCGCCAAG
CGCTGCTCGATCTTGAGCATGAACTCTATTGCGCCTGA

Upstream 100 bases:

>100_bases
ACCTTTGCTAAGTACCTGGTTTCCTTATTGATTCACCTGTTGCGCGCAACTGATTCCCATCTTTTATCGGCTTGACGCAA
CAAGATTGAAGAGCGCTCTG

Downstream 100 bases:

>100_bases
AAACAACAACTTGACAGACAATCAGTAATGTCTATCCAGAACCTCGTAAAATCCATACAGGATATCATGCGCAAGGATGT
TGGCGTTGATGGCGACGCTC

Product: EcoEI R domain-containing protein

Products: NA

Alternate protein names: R.EcoAI [H]

Number of amino acids: Translated: 785; Mature: 785

Protein sequence:

>785_residues
MDKKQLSERDICTKFITPSLEQVGWDIATQVREEFPLTNGRIIVRGSVHTRGSRKRADYVLFYKPNIPIAVIEAKDNKHS
LGDGMQQALGYADLLQVPFVFSSNGDGFLFHNKLAPDGIIERELALHEFPSAETLWQWWAAHRGLDDRQNNLVTQDYFSD
GSGKTPRYYQLLAINKTVEAIAGGQNRILLVMATGTGKTFTAFQIIWRLWKSKAKKRILFLADRNILVDQAITNDFKPFG
SAMTKIQKRQADKSYEIYLSLYQAVTGNEEEKNIYKQFSPDFFDLVIIDECHRGSAAEDSAWREILEYFNSATQIGLTAT
PKETKEVSNIDYFGEPIYTYSLKQGINDGFLAPYKVVRIDIDKDLEGWRPDKGMLDKYGNEIEDRIYNQRDFDRSLVLEK
RTELVARKVSDFLRRTNRFDKTIIFCENIEHAERMRQALVNENSDLASKHDKYVVRITGDNEEGKAELDNFIFPEKTFPV
IATTSKLMTTGVDAQTCKLIVLDQRIQSMTEFKQIIGRGTRINEEFGKFYFTIIDFKKATELFADPDFDGDPVQIYEPQA
GDSPLPPDISGGEPYPEGQEDQDWPDLQDKPVTGGVRRYVVDNVEVRVVAERVQYFDANGKLITESLRDYTRKALAGEFE
SLYDFLNRWNSAEQKQAIIDELAEHGIFFEALADEIGRKSGKSFDPFDLICHVAWDMPPLSRKERAEQVKKRNYFTKYGE
EARKVLEALLDKYADEGIGHVEETQILTISPFTEIGTPMEIVRFFGGVDGYRQALLDLEHELYCA

Sequences:

>Translated_785_residues
MDKKQLSERDICTKFITPSLEQVGWDIATQVREEFPLTNGRIIVRGSVHTRGSRKRADYVLFYKPNIPIAVIEAKDNKHS
LGDGMQQALGYADLLQVPFVFSSNGDGFLFHNKLAPDGIIERELALHEFPSAETLWQWWAAHRGLDDRQNNLVTQDYFSD
GSGKTPRYYQLLAINKTVEAIAGGQNRILLVMATGTGKTFTAFQIIWRLWKSKAKKRILFLADRNILVDQAITNDFKPFG
SAMTKIQKRQADKSYEIYLSLYQAVTGNEEEKNIYKQFSPDFFDLVIIDECHRGSAAEDSAWREILEYFNSATQIGLTAT
PKETKEVSNIDYFGEPIYTYSLKQGINDGFLAPYKVVRIDIDKDLEGWRPDKGMLDKYGNEIEDRIYNQRDFDRSLVLEK
RTELVARKVSDFLRRTNRFDKTIIFCENIEHAERMRQALVNENSDLASKHDKYVVRITGDNEEGKAELDNFIFPEKTFPV
IATTSKLMTTGVDAQTCKLIVLDQRIQSMTEFKQIIGRGTRINEEFGKFYFTIIDFKKATELFADPDFDGDPVQIYEPQA
GDSPLPPDISGGEPYPEGQEDQDWPDLQDKPVTGGVRRYVVDNVEVRVVAERVQYFDANGKLITESLRDYTRKALAGEFE
SLYDFLNRWNSAEQKQAIIDELAEHGIFFEALADEIGRKSGKSFDPFDLICHVAWDMPPLSRKERAEQVKKRNYFTKYGE
EARKVLEALLDKYADEGIGHVEETQILTISPFTEIGTPMEIVRFFGGVDGYRQALLDLEHELYCA
>Mature_785_residues
MDKKQLSERDICTKFITPSLEQVGWDIATQVREEFPLTNGRIIVRGSVHTRGSRKRADYVLFYKPNIPIAVIEAKDNKHS
LGDGMQQALGYADLLQVPFVFSSNGDGFLFHNKLAPDGIIERELALHEFPSAETLWQWWAAHRGLDDRQNNLVTQDYFSD
GSGKTPRYYQLLAINKTVEAIAGGQNRILLVMATGTGKTFTAFQIIWRLWKSKAKKRILFLADRNILVDQAITNDFKPFG
SAMTKIQKRQADKSYEIYLSLYQAVTGNEEEKNIYKQFSPDFFDLVIIDECHRGSAAEDSAWREILEYFNSATQIGLTAT
PKETKEVSNIDYFGEPIYTYSLKQGINDGFLAPYKVVRIDIDKDLEGWRPDKGMLDKYGNEIEDRIYNQRDFDRSLVLEK
RTELVARKVSDFLRRTNRFDKTIIFCENIEHAERMRQALVNENSDLASKHDKYVVRITGDNEEGKAELDNFIFPEKTFPV
IATTSKLMTTGVDAQTCKLIVLDQRIQSMTEFKQIIGRGTRINEEFGKFYFTIIDFKKATELFADPDFDGDPVQIYEPQA
GDSPLPPDISGGEPYPEGQEDQDWPDLQDKPVTGGVRRYVVDNVEVRVVAERVQYFDANGKLITESLRDYTRKALAGEFE
SLYDFLNRWNSAEQKQAIIDELAEHGIFFEALADEIGRKSGKSFDPFDLICHVAWDMPPLSRKERAEQVKKRNYFTKYGE
EARKVLEALLDKYADEGIGHVEETQILTISPFTEIGTPMEIVRFFGGVDGYRQALLDLEHELYCA

Specific function: The EcoAI enzyme recognizes 5'-GAGN(7)GTCA-3'. Subunit R is required for both nuclease and ATPase activities, but not for modification [H]

COG id: COG4096

COG function: function code V; Type I site-specific restriction-modification system, R (restriction) subunit and related helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI226510991, Length=576, Percent_Identity=28.6458333333333, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI1788511, Length=429, Percent_Identity=25.4079254079254, Blast_Score=87, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935
- InterPro:   IPR013670
- InterPro:   IPR007409 [H]

Pfam domain/function: PF08463 EcoEI_R_C; PF04313 HSDR_N; PF04851 ResIII [H]

EC number: =3.1.21.3 [H]

Molecular weight: Translated: 89955; Mature: 89955

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKKQLSERDICTKFITPSLEQVGWDIATQVREEFPLTNGRIIVRGSVHTRGSRKRADYV
CCHHHHHHHHHHHHHCCCCHHHHCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEE
LFYKPNIPIAVIEAKDNKHSLGDGMQQALGYADLLQVPFVFSSNGDGFLFHNKLAPDGII
EEECCCCCEEEEECCCCCCHHHHHHHHHHCHHHHHHCCEEEECCCCEEEEECCCCCCCHH
ERELALHEFPSAETLWQWWAAHRGLDDRQNNLVTQDYFSDGSGKTPRYYQLLAINKTVEA
HHHHHHHCCCCHHHHHHHHHHHCCCCCHHCCCEEHHHCCCCCCCCCCEEEEEEECHHHHH
IAGGQNRILLVMATGTGKTFTAFQIIWRLWKSKAKKRILFLADRNILVDQAITNDFKPFG
HCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCEEEEEECCCEEEHHHHHCCCCHHH
SAMTKIQKRQADKSYEIYLSLYQAVTGNEEEKNIYKQFSPDFFDLVIIDECHRGSAAEDS
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCHH
AWREILEYFNSATQIGLTATPKETKEVSNIDYFGEPIYTYSLKQGINDGFLAPYKVVRID
HHHHHHHHHCCHHCCCEECCCHHHHHHCCCCCCCCCEEEEEHHHCCCCCCCCCEEEEEEE
IDKDLEGWRPDKGMLDKYGNEIEDRIYNQRDFDRSLVLEKRTELVARKVSDFLRRTNRFD
ECCCCCCCCCCCCHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
KTIIFCENIEHAERMRQALVNENSDLASKHDKYVVRITGDNEEGKAELDNFIFPEKTFPV
CEEEEECCCHHHHHHHHHHHCCCCCHHCCCCCEEEEEECCCCCCHHHHHHCCCCCCCCCE
IATTSKLMTTGVDAQTCKLIVLDQRIQSMTEFKQIIGRGTRINEEFGKFYFTIIDFKKAT
EEECHHHHHCCCCHHHEEEEEHHHHHHHHHHHHHHHCCCCCCCHHHCCEEEEEEEHHHHH
ELFADPDFDGDPVQIYEPQAGDSPLPPDISGGEPYPEGQEDQDWPDLQDKPVTGGVRRYV
HHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
VDNVEVRVVAERVQYFDANGKLITESLRDYTRKALAGEFESLYDFLNRWNSAEQKQAIID
HCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
ELAEHGIFFEALADEIGRKSGKSFDPFDLICHVAWDMPPLSRKERAEQVKKRNYFTKYGE
HHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
EARKVLEALLDKYADEGIGHVEETQILTISPFTEIGTPMEIVRFFGGVDGYRQALLDLEH
HHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHCCHHHHHHHHCCCCHHHHHHHHHHH
ELYCA
HHHCC
>Mature Secondary Structure
MDKKQLSERDICTKFITPSLEQVGWDIATQVREEFPLTNGRIIVRGSVHTRGSRKRADYV
CCHHHHHHHHHHHHHCCCCHHHHCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEE
LFYKPNIPIAVIEAKDNKHSLGDGMQQALGYADLLQVPFVFSSNGDGFLFHNKLAPDGII
EEECCCCCEEEEECCCCCCHHHHHHHHHHCHHHHHHCCEEEECCCCEEEEECCCCCCCHH
ERELALHEFPSAETLWQWWAAHRGLDDRQNNLVTQDYFSDGSGKTPRYYQLLAINKTVEA
HHHHHHHCCCCHHHHHHHHHHHCCCCCHHCCCEEHHHCCCCCCCCCCEEEEEEECHHHHH
IAGGQNRILLVMATGTGKTFTAFQIIWRLWKSKAKKRILFLADRNILVDQAITNDFKPFG
HCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCEEEEEECCCEEEHHHHHCCCCHHH
SAMTKIQKRQADKSYEIYLSLYQAVTGNEEEKNIYKQFSPDFFDLVIIDECHRGSAAEDS
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCHH
AWREILEYFNSATQIGLTATPKETKEVSNIDYFGEPIYTYSLKQGINDGFLAPYKVVRID
HHHHHHHHHCCHHCCCEECCCHHHHHHCCCCCCCCCEEEEEHHHCCCCCCCCCEEEEEEE
IDKDLEGWRPDKGMLDKYGNEIEDRIYNQRDFDRSLVLEKRTELVARKVSDFLRRTNRFD
ECCCCCCCCCCCCHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
KTIIFCENIEHAERMRQALVNENSDLASKHDKYVVRITGDNEEGKAELDNFIFPEKTFPV
CEEEEECCCHHHHHHHHHHHCCCCCHHCCCCCEEEEEECCCCCCHHHHHHCCCCCCCCCE
IATTSKLMTTGVDAQTCKLIVLDQRIQSMTEFKQIIGRGTRINEEFGKFYFTIIDFKKAT
EEECHHHHHCCCCHHHEEEEEHHHHHHHHHHHHHHHCCCCCCCHHHCCEEEEEEEHHHHH
ELFADPDFDGDPVQIYEPQAGDSPLPPDISGGEPYPEGQEDQDWPDLQDKPVTGGVRRYV
HHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
VDNVEVRVVAERVQYFDANGKLITESLRDYTRKALAGEFESLYDFLNRWNSAEQKQAIID
HCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
ELAEHGIFFEALADEIGRKSGKSFDPFDLICHVAWDMPPLSRKERAEQVKKRNYFTKYGE
HHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
EARKVLEALLDKYADEGIGHVEETQILTISPFTEIGTPMEIVRFFGGVDGYRQALLDLEH
HHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHCCHHHHHHHHCCCCHHHHHHHHHHH
ELYCA
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8412658 [H]