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The map label for this gene is guaA [H]

Identifier: 193212424

GI number: 193212424

Start: 817311

End: 818030

Strand: Direct

Name: guaA [H]

Synonym: Cpar_0760

Alternate gene names: 193212424

Gene position: 817311-818030 (Clockwise)

Preceding gene: 193212421

Following gene: 193212427

Centisome position: 35.7

GC content: 64.17

Gene sequence:

>720_bases
ATGAAAAGTCTGTATATCATCAAGGCCGGGAGCACCTTTGCCACCGAGGTGGCGCGGCTCGGCGATTTCGAAGAGTGGGT
GCGGCGCGGACTGGGCGACGTGGCGTGTCCGGTTGCGGTGGTGAACGCTGAGGGCGGCGAGGCGTTGCCAGCGCCGGAGC
TGTGCGCCGGGGCGGTCGTGACCGGCTCGCACGCCATGGTGACCGACAATTTGCCGTGGAGCCTCGGCATCGAGCGGTGG
ATTCGCGAGCTGATCGCCGTCCGTGTGCCTTTCCTCGGCATCTGCTACGGCCACCAGCTTCTCGGACGGGCGGCTGGCGG
CGAGGTGGGCTACCATCCGCGAGGTCGGGAGGTCGGCACGGTCTCCATCGAACTGACGCCTGAAGGCCAGCGCGATTCGC
TTTTCGAAGCCATTCCGGCGCGGTTCGTAGCGCACGCGACTCATGCGCAGAGCGTGTTGCGGCTGCCGGAGGGCGCTGTC
CATCTCGCTTTCAACGGCTTCGAATCGCATCACGCCTTCCAGGTCGGTGAATCGGCTTGGGGTGTGCAGTTCCATCCGGA
GTACACGCGGGAGATCATGCAGACCTATGTGCGCGATGAGATCGCTGGCCTTGAAGCGGTTGGCGAAGATGCCGGAGCGT
TACGCGAGGTTGTGTCGGACGCGCCGTTCGCCGGGCGGGTGCTTACAAATTTTGCCAGCTTTGTTTTCCGGACTCTTTGA

Upstream 100 bases:

>100_bases
TACGAAAAAACGGAGCGATAACCGGCGAGGTGCGATTGTTTCAGCCGCTGAAAGATGATAGCTTTGGGGCAGAAATTTCG
ATCACTGGACATTATGGTCT

Downstream 100 bases:

>100_bases
GCCGTTGCACGAGGCCGGTCAGGCGGCGTTTCGATTTACAGTTCCTGATCGCCCGGTCAAGCGCCTTCGGTTCGGCAACG
ATGACCACGAGCTTGCGTCC

Product: glutamine amidotransferase

Products: NA

Alternate protein names: GMP synthetase; Glutamine amidotransferase [H]

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MKSLYIIKAGSTFATEVARLGDFEEWVRRGLGDVACPVAVVNAEGGEALPAPELCAGAVVTGSHAMVTDNLPWSLGIERW
IRELIAVRVPFLGICYGHQLLGRAAGGEVGYHPRGREVGTVSIELTPEGQRDSLFEAIPARFVAHATHAQSVLRLPEGAV
HLAFNGFESHHAFQVGESAWGVQFHPEYTREIMQTYVRDEIAGLEAVGEDAGALREVVSDAPFAGRVLTNFASFVFRTL

Sequences:

>Translated_239_residues
MKSLYIIKAGSTFATEVARLGDFEEWVRRGLGDVACPVAVVNAEGGEALPAPELCAGAVVTGSHAMVTDNLPWSLGIERW
IRELIAVRVPFLGICYGHQLLGRAAGGEVGYHPRGREVGTVSIELTPEGQRDSLFEAIPARFVAHATHAQSVLRLPEGAV
HLAFNGFESHHAFQVGESAWGVQFHPEYTREIMQTYVRDEIAGLEAVGEDAGALREVVSDAPFAGRVLTNFASFVFRTL
>Mature_239_residues
MKSLYIIKAGSTFATEVARLGDFEEWVRRGLGDVACPVAVVNAEGGEALPAPELCAGAVVTGSHAMVTDNLPWSLGIERW
IRELIAVRVPFLGICYGHQLLGRAAGGEVGYHPRGREVGTVSIELTPEGQRDSLFEAIPARFVAHATHAQSVLRLPEGAV
HLAFNGFESHHAFQVGESAWGVQFHPEYTREIMQTYVRDEIAGLEAVGEDAGALREVVSDAPFAGRVLTNFASFVFRTL

Specific function: Catalyzes the synthesis of GMP from XMP [H]

COG id: COG0518

COG function: function code F; GMP synthase - Glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GMP-binding domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323155, Length=142, Percent_Identity=30.2816901408451, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR001674
- InterPro:   IPR004739
- InterPro:   IPR022955
- InterPro:   IPR022310
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00117 GATase; PF00958 GMP_synt_C; PF02540 NAD_synthase [H]

EC number: =6.3.5.2 [H]

Molecular weight: Translated: 25840; Mature: 25840

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSLYIIKAGSTFATEVARLGDFEEWVRRGLGDVACPVAVVNAEGGEALPAPELCAGAVV
CCCEEEEECCCHHHHHHHHCCCHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHCCCEE
TGSHAMVTDNLPWSLGIERWIRELIAVRVPFLGICYGHQLLGRAAGGEVGYHPRGREVGT
ECCCEEEECCCCHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEE
VSIELTPEGQRDSLFEAIPARFVAHATHAQSVLRLPEGAVHLAFNGFESHHAFQVGESAW
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEECCCCC
GVQFHPEYTREIMQTYVRDEIAGLEAVGEDAGALREVVSDAPFAGRVLTNFASFVFRTL
CCEECHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKSLYIIKAGSTFATEVARLGDFEEWVRRGLGDVACPVAVVNAEGGEALPAPELCAGAVV
CCCEEEEECCCHHHHHHHHCCCHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHCCCEE
TGSHAMVTDNLPWSLGIERWIRELIAVRVPFLGICYGHQLLGRAAGGEVGYHPRGREVGT
ECCCEEEECCCCHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEE
VSIELTPEGQRDSLFEAIPARFVAHATHAQSVLRLPEGAVHLAFNGFESHHAFQVGESAW
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEECCCCC
GVQFHPEYTREIMQTYVRDEIAGLEAVGEDAGALREVVSDAPFAGRVLTNFASFVFRTL
CCEECHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10382966 [H]