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The map label for this gene is coaX

Identifier: 193212421

GI number: 193212421

Start: 814502

End: 815308

Strand: Direct

Name: coaX

Synonym: Cpar_0757

Alternate gene names: 193212421

Gene position: 814502-815308 (Clockwise)

Preceding gene: 193212420

Following gene: 193212424

Centisome position: 35.58

GC content: 59.85

Gene sequence:

>807_bases
ATGCAGAGTTCCAGAAGCGTTTCGACTGAGGCGTTCGTGCGGCTGGTCGTTGATATCGGCAACACCACCACGACGCTGGC
CGTGTTCACCGGAGAGACTGAGCCGTCGGTCGAATCGGTTCAGAGCACGCTGTTCGGTGAGCCGAAAGCGGTTGCCGAGC
TGTTTCTCTCGCTGGCTCATCGGCACGGTACGCCTCAGGCTGTTGCGGTGTGCAGCGTAGTGCCAGCCGCGGCAGCCTCC
TGCTCGGCGCAACTCGAATCGCTTTTTTCTGTGCCCGTGGTGACGATCGCTGCCTCGCTTCGCCTGCCGTTCCAGCTTGA
TTATGCAACTCCGCACACCTTTGGCGCGGATCGTATCGCGCTGTGCGCCTGGAGCCGACATCTGTTCGGCGACTGCCCGG
TGATCGCGGTCGATATCGGTACAGCGATTACCTTCGATGTGCTCGATGCTGAGGGAAACTATCGTGGCGGGTTGATTATG
CCGGGGATCGATATGATGGCCGGAGCGCTCAATTCGAGAACCGCGCAGCTTCCGCTGGTCGACATCGACAAGCCGGAAAG
CCTGCTTGGTCGATCCACCATCGAGTGTATCAGAAACGGCATTTTCTGGGGAGCGGTCAGACAGATTGCCGGGCTGATCG
ACGCCATCGGGGCAGAGCTGCCGGGCGAGTCAAAAGCTGCTCCAGCCGAAGTGCTTGTTACCGGCGGCAACAGCCGGATT
ATCGCTCCTGAGATCGCTTCAATTACCCACCTCGACGAGCTTGCCGTGCTTCGCGGAATCGACCTGCTGCTACGACTGAA
CTCATGA

Upstream 100 bases:

>100_bases
GGACGGCCTGCCGGATGCTGGCAAGATGCTCTCAGAGCTGTCGAAGCGAAGCGGCGTGACCGTCAAGAGGCCGTAATCCT
GCTGTTTCCGGGAAACTTCC

Downstream 100 bases:

>100_bases
GCTTGTTCAGAGGACAAGCAGGGGCTGTTTTTTTCTCCTTCAAAATCGCATCAAATGCAGGAAGATCGTAGGGGCAACCC
TTGCGGTTGCCCCGTTCGGG

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MQSSRSVSTEAFVRLVVDIGNTTTTLAVFTGETEPSVESVQSTLFGEPKAVAELFLSLAHRHGTPQAVAVCSVVPAAAAS
CSAQLESLFSVPVVTIAASLRLPFQLDYATPHTFGADRIALCAWSRHLFGDCPVIAVDIGTAITFDVLDAEGNYRGGLIM
PGIDMMAGALNSRTAQLPLVDIDKPESLLGRSTIECIRNGIFWGAVRQIAGLIDAIGAELPGESKAAPAEVLVTGGNSRI
IAPEIASITHLDELAVLRGIDLLLRLNS

Sequences:

>Translated_268_residues
MQSSRSVSTEAFVRLVVDIGNTTTTLAVFTGETEPSVESVQSTLFGEPKAVAELFLSLAHRHGTPQAVAVCSVVPAAAAS
CSAQLESLFSVPVVTIAASLRLPFQLDYATPHTFGADRIALCAWSRHLFGDCPVIAVDIGTAITFDVLDAEGNYRGGLIM
PGIDMMAGALNSRTAQLPLVDIDKPESLLGRSTIECIRNGIFWGAVRQIAGLIDAIGAELPGESKAAPAEVLVTGGNSRI
IAPEIASITHLDELAVLRGIDLLLRLNS
>Mature_268_residues
MQSSRSVSTEAFVRLVVDIGNTTTTLAVFTGETEPSVESVQSTLFGEPKAVAELFLSLAHRHGTPQAVAVCSVVPAAAAS
CSAQLESLFSVPVVTIAASLRLPFQLDYATPHTFGADRIALCAWSRHLFGDCPVIAVDIGTAITFDVLDAEGNYRGGLIM
PGIDMMAGALNSRTAQLPLVDIDKPESLLGRSTIECIRNGIFWGAVRQIAGLIDAIGAELPGESKAAPAEVLVTGGNSRI
IAPEIASITHLDELAVLRGIDLLLRLNS

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_CHLP8 (B3QMM1)

Other databases:

- EMBL:   CP001099
- RefSeq:   YP_001998374.1
- GeneID:   6419684
- GenomeReviews:   CP001099_GR
- KEGG:   cpc:Cpar_0757
- HOGENOM:   HBG634537
- OMA:   IMPGLEL
- ProtClustDB:   PRK13320
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 28149; Mature: 28149

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: ACT_SITE 117-117 BINDING 108-108 BINDING 141-141 BINDING 193-193

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSSRSVSTEAFVRLVVDIGNTTTTLAVFTGETEPSVESVQSTLFGEPKAVAELFLSLAH
CCCCCCCCHHHHHEEEEECCCCEEEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHH
RHGTPQAVAVCSVVPAAAASCSAQLESLFSVPVVTIAASLRLPFQLDYATPHTFGADRIA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHH
LCAWSRHLFGDCPVIAVDIGTAITFDVLDAEGNYRGGLIMPGIDMMAGALNSRTAQLPLV
HHHHHHHHCCCCCEEEEECCCEEEEEEEECCCCCCCCEEECCHHHHHHHHCCCCCCCCEE
DIDKPESLLGRSTIECIRNGIFWGAVRQIAGLIDAIGAELPGESKAAPAEVLVTGGNSRI
ECCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEE
IAPEIASITHLDELAVLRGIDLLLRLNS
ECCCHHHHHHHHHHHHHHHCEEEEEECC
>Mature Secondary Structure
MQSSRSVSTEAFVRLVVDIGNTTTTLAVFTGETEPSVESVQSTLFGEPKAVAELFLSLAH
CCCCCCCCHHHHHEEEEECCCCEEEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHH
RHGTPQAVAVCSVVPAAAASCSAQLESLFSVPVVTIAASLRLPFQLDYATPHTFGADRIA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHH
LCAWSRHLFGDCPVIAVDIGTAITFDVLDAEGNYRGGLIMPGIDMMAGALNSRTAQLPLV
HHHHHHHHCCCCCEEEEECCCEEEEEEEECCCCCCCCEEECCHHHHHHHHCCCCCCCCEE
DIDKPESLLGRSTIECIRNGIFWGAVRQIAGLIDAIGAELPGESKAAPAEVLVTGGNSRI
ECCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEE
IAPEIASITHLDELAVLRGIDLLLRLNS
ECCCHHHHHHHHHHHHHHHCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA