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The map label for this gene is fchA [H]

Identifier: 193212354

GI number: 193212354

Start: 733435

End: 734058

Strand: Direct

Name: fchA [H]

Synonym: Cpar_0687

Alternate gene names: 193212354

Gene position: 733435-734058 (Clockwise)

Preceding gene: 193212353

Following gene: 193212357

Centisome position: 32.04

GC content: 61.54

Gene sequence:

>624_bases
ATGAAGCCTGACGGTACGCTTGAATCGACCACCATTGCCGCCTACCTCGGTCGGCTCGCCAGCGGTGATCCCACGCCGGG
TGGTGGGGCGGCAGCGGCAGTGACGGCCGCACAGGGCGTCGCTCTGCTCTCGATGGTCTGCAACCTGACACTCGGCAAGA
AGAGGTTCGCCGACGTCGAGGATGAAGTTCAATCGATTCTCGAAACGTGTGAAACGGCCCGCCGCCAGATGCTCGTTCTC
GGCGACCGAGACATGGAGGTGTTCGGCGCGATCATGGAGGTTTACAGGCTGCCGAAAACGACGCCCGAAGAGACCGAGGC
TCGCAGTGCCGCCATCCAGGCTGCGCTGAAGGCCAGCTCCGAAGTGCCGTTCGAGCTTTTCAAGCGGTGCCAAGCTCTGC
GGCCTCTTGCTGATCGCCTTGAACAGATCGGTAATCCCAACGTACTCAGCGATGTGATCGTCGGTCGCCACCTGCTGATT
GCAGGCATGCTGAGCGCCAGGGCCAACGTCGAGGTTAACCTCGACGGCATTGATGATGCCGAGTTCTGTGAGGCGAAGCG
TACGGTCATGCAGCAGGCGCTCGACGGGCTTGGCGAAAGCTGCCAAGGCTTGGTGGGGAGATAA

Upstream 100 bases:

>100_bases
GATGCCAAGGAATCGGCCGGGCTCTACATTCCGAGGGTCGGCCCCATGACGGTGGCCATGTGCATGCGCAACGCCCTGCA
ACTCTATCGCAACTACCATC

Downstream 100 bases:

>100_bases
TCAGATCGGTCAGATCAGACGCATCCGACCGATCTGTCTGATTTTTCAAACACAAAAAAAAGCCGCCTTGAAAAAGGGCG
GCTTTTTTGCGTTGATCCGG

Product: Formiminotransferase-cyclodeaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MKPDGTLESTTIAAYLGRLASGDPTPGGGAAAAVTAAQGVALLSMVCNLTLGKKRFADVEDEVQSILETCETARRQMLVL
GDRDMEVFGAIMEVYRLPKTTPEETEARSAAIQAALKASSEVPFELFKRCQALRPLADRLEQIGNPNVLSDVIVGRHLLI
AGMLSARANVEVNLDGIDDAEFCEAKRTVMQQALDGLGESCQGLVGR

Sequences:

>Translated_207_residues
MKPDGTLESTTIAAYLGRLASGDPTPGGGAAAAVTAAQGVALLSMVCNLTLGKKRFADVEDEVQSILETCETARRQMLVL
GDRDMEVFGAIMEVYRLPKTTPEETEARSAAIQAALKASSEVPFELFKRCQALRPLADRLEQIGNPNVLSDVIVGRHLLI
AGMLSARANVEVNLDGIDDAEFCEAKRTVMQQALDGLGESCQGLVGR
>Mature_207_residues
MKPDGTLESTTIAAYLGRLASGDPTPGGGAAAAVTAAQGVALLSMVCNLTLGKKRFADVEDEVQSILETCETARRQMLVL
GDRDMEVFGAIMEVYRLPKTTPEETEARSAAIQAALKASSEVPFELFKRCQALRPLADRLEQIGNPNVLSDVIVGRHLLI
AGMLSARANVEVNLDGIDDAEFCEAKRTVMQQALDGLGESCQGLVGR

Specific function: Required for both C1 and C2 metabolism [H]

COG id: COG3404

COG function: function code E; Methenyl tetrahydrofolate cyclohydrolase

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cyclodeaminase/cyclohydrolase family [H]

Homologues:

Organism=Homo sapiens, GI46255035, Length=180, Percent_Identity=35.5555555555556, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI11140815, Length=180, Percent_Identity=35.5555555555556, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007044 [H]

Pfam domain/function: PF04961 FTCD_C [H]

EC number: =3.5.4.9 [H]

Molecular weight: Translated: 22050; Mature: 22050

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPDGTLESTTIAAYLGRLASGDPTPGGGAAAAVTAAQGVALLSMVCNLTLGKKRFADVE
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHCCHH
DEVQSILETCETARRQMLVLGDRDMEVFGAIMEVYRLPKTTPEETEARSAAIQAALKASS
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCC
EVPFELFKRCQALRPLADRLEQIGNPNVLSDVIVGRHLLIAGMLSARANVEVNLDGIDDA
CCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCH
EFCEAKRTVMQQALDGLGESCQGLVGR
HHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKPDGTLESTTIAAYLGRLASGDPTPGGGAAAAVTAAQGVALLSMVCNLTLGKKRFADVE
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHCCHH
DEVQSILETCETARRQMLVLGDRDMEVFGAIMEVYRLPKTTPEETEARSAAIQAALKASS
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCC
EVPFELFKRCQALRPLADRLEQIGNPNVLSDVIVGRHLLIAGMLSARANVEVNLDGIDDA
CCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCH
EFCEAKRTVMQQALDGLGESCQGLVGR
HHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7961516; 10215859 [H]