Click here to switch to the map view.

The map label for this gene is tolB [H]

Identifier: 193212307

GI number: 193212307

Start: 685567

End: 686871

Strand: Direct

Name: tolB [H]

Synonym: Cpar_0640

Alternate gene names: 193212307

Gene position: 685567-686871 (Clockwise)

Preceding gene: 193212306

Following gene: 193212308

Centisome position: 29.95

GC content: 51.49

Gene sequence:

>1305_bases
ATGAAAACCGCCAGGATTTCTTCAGTTCGTACTCTTATTGCCCTTTTTTGCCTTTTTATGGTCCCTTTTACCATCAGGGC
GGAGGAGGTAAACGAGTATATCGCCATCCGCAAGGAGGGGAGTGGCAGAATTTCGATCATTCTCGACCATCTCAAGTCCA
ACGGCGGCAAGGAATCCGAATGGGCCAGAAGTCTGGACAGCACCATCCAGGGTGGGCTTGATTTTACCGGTTTGTTCAAC
CTTATGCCGGCGCCACTGAATATCCGGAATGCGCAGAATGGTGCTTTGAATCTCGGCGCTGTCAGGTCGATTGGCGCCGA
TGTGTTTGTCGGCGGCAGCGTGACGAAGCAGAGCGGCGATCCGGCCATGCAGATGCAGGTGTGGGATGTTACCGGCAAGC
TGCTGCTCAATCGGAAATATAGTGGCCAGGACAAGGCGCTTCGCGATATCGGTTTGCGTTTCTGCGCCGATCTGGTCGAG
ATGCTTACCGGTAAACGGTCGGTCTTTGGCACCAAAATGGTTTTTGTATCAAATAGCACCGGCCAGAAAGAGATTTATAT
GTGCGATTTCGACGGGACGAACATCCGTCAGCTTACCAATACGAAGTCGATTTCACTTACGCCCTCAGTATCGCCAGATG
GGAGGTTTCTTGCCTGGACTGATTTTTCAAGCGGCCGTCCCGATCTCTACATCAAAAATCTTTCCACCGGCTCGACGGTT
TCGGTTAAAAAGCAGGGCGTTTGTATCAGTCCGGCCTGGCGTCCCGGCACCAACGAGTGTGCTACAACCCTGTCTTACGA
AGGTTCACAAGACCTTTATCTTATCAGGGCTGACGGGACTGTCGCTCGCCGATTGACCAGGGGGCACAGTATCGAGGTCT
CTCCGAGTTTTTCACCTGATGGTTCCAAAATGGCGTTTGTCTCGACCCGGGAAGGCCCTCCGCAGATTTTCATTCAGGAT
CTTTCAAGTGGAAGCGTCAGGCGGCTTACCTACAGCGGCACCTACAATACCCAGCCGTCCTGGTCGCCATCTGGCGATAA
AATCTTGTACTCGTCCCTGCAAAAGAACGGTGAAATCAATATATTTATGATCAATGTCGATGGTTCAAATCTGCTTCAAT
TGACCAGCGGCGCAAGGAATAATGAGTACCCCTCATGGTCACCCGATGGAAGCATGATTGTTTTTTCATCAACCCGGGCC
GGCTCGAGAAAATTATATGTTATGAATGTCGACGGGACCAACCAGCGGCCCTTGCTCAATATGAAGGGTGAGCAGCAGCA
GCCGTCATGGTCGATCAGGAATTAA

Upstream 100 bases:

>100_bases
TGCATAGACTGAAAAGCGCGTATTGTTGTTTTGTGTATATTTTTTCTTTGCCGGTTGCGGTGTGTTCGGCTTCAACAATG
TTCAATCCAGTTAGCTTGTT

Downstream 100 bases:

>100_bases
CCGGTTTTTCTTCTCGTCAATCTTTTAATCAGTGGAGGACTATATGACCCCTGTTAAAGCGATCACCAGAGCCCTGTACG
TTCCGGCAGTGCTGTTTCTC

Product: Tol-Pal system beta propeller repeat-containing protein TolB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MKTARISSVRTLIALFCLFMVPFTIRAEEVNEYIAIRKEGSGRISIILDHLKSNGGKESEWARSLDSTIQGGLDFTGLFN
LMPAPLNIRNAQNGALNLGAVRSIGADVFVGGSVTKQSGDPAMQMQVWDVTGKLLLNRKYSGQDKALRDIGLRFCADLVE
MLTGKRSVFGTKMVFVSNSTGQKEIYMCDFDGTNIRQLTNTKSISLTPSVSPDGRFLAWTDFSSGRPDLYIKNLSTGSTV
SVKKQGVCISPAWRPGTNECATTLSYEGSQDLYLIRADGTVARRLTRGHSIEVSPSFSPDGSKMAFVSTREGPPQIFIQD
LSSGSVRRLTYSGTYNTQPSWSPSGDKILYSSLQKNGEINIFMINVDGSNLLQLTSGARNNEYPSWSPDGSMIVFSSTRA
GSRKLYVMNVDGTNQRPLLNMKGEQQQPSWSIRN

Sequences:

>Translated_434_residues
MKTARISSVRTLIALFCLFMVPFTIRAEEVNEYIAIRKEGSGRISIILDHLKSNGGKESEWARSLDSTIQGGLDFTGLFN
LMPAPLNIRNAQNGALNLGAVRSIGADVFVGGSVTKQSGDPAMQMQVWDVTGKLLLNRKYSGQDKALRDIGLRFCADLVE
MLTGKRSVFGTKMVFVSNSTGQKEIYMCDFDGTNIRQLTNTKSISLTPSVSPDGRFLAWTDFSSGRPDLYIKNLSTGSTV
SVKKQGVCISPAWRPGTNECATTLSYEGSQDLYLIRADGTVARRLTRGHSIEVSPSFSPDGSKMAFVSTREGPPQIFIQD
LSSGSVRRLTYSGTYNTQPSWSPSGDKILYSSLQKNGEINIFMINVDGSNLLQLTSGARNNEYPSWSPDGSMIVFSSTRA
GSRKLYVMNVDGTNQRPLLNMKGEQQQPSWSIRN
>Mature_434_residues
MKTARISSVRTLIALFCLFMVPFTIRAEEVNEYIAIRKEGSGRISIILDHLKSNGGKESEWARSLDSTIQGGLDFTGLFN
LMPAPLNIRNAQNGALNLGAVRSIGADVFVGGSVTKQSGDPAMQMQVWDVTGKLLLNRKYSGQDKALRDIGLRFCADLVE
MLTGKRSVFGTKMVFVSNSTGQKEIYMCDFDGTNIRQLTNTKSISLTPSVSPDGRFLAWTDFSSGRPDLYIKNLSTGSTV
SVKKQGVCISPAWRPGTNECATTLSYEGSQDLYLIRADGTVARRLTRGHSIEVSPSFSPDGSKMAFVSTREGPPQIFIQD
LSSGSVRRLTYSGTYNTQPSWSPSGDKILYSSLQKNGEINIFMINVDGSNLLQLTSGARNNEYPSWSPDGSMIVFSSTRA
GSRKLYVMNVDGTNQRPLLNMKGEQQQPSWSIRN

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0823

COG function: function code U; Periplasmic component of the Tol biopolymer transport system

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tolB family [H]

Homologues:

Organism=Escherichia coli, GI1786961, Length=343, Percent_Identity=28.2798833819242, Blast_Score=127, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI32564215, Length=211, Percent_Identity=24.6445497630332, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI32564217, Length=211, Percent_Identity=24.6445497630332, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011659
- InterPro:   IPR014167
- InterPro:   IPR007195
- InterPro:   IPR015943 [H]

Pfam domain/function: PF07676 PD40; PF04052 TolB_N [H]

EC number: NA

Molecular weight: Translated: 47607; Mature: 47607

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTARISSVRTLIALFCLFMVPFTIRAEEVNEYIAIRKEGSGRISIILDHLKSNGGKESE
CCCCHHHHHHHHHHHHHHHHCCCEEEHHHCCCEEEEEECCCCEEEEEEEEHHCCCCCCHH
WARSLDSTIQGGLDFTGLFNLMPAPLNIRNAQNGALNLGAVRSIGADVFVGGSVTKQSGD
HHHHHHHHHHCCCCEEEHHHCCCCCEEECCCCCCCEEECHHHHCCCCEEECCCEECCCCC
PAMQMQVWDVTGKLLLNRKYSGQDKALRDIGLRFCADLVEMLTGKRSVFGTKMVFVSNST
CEEEEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCC
GQKEIYMCDFDGTNIRQLTNTKSISLTPSVSPDGRFLAWTDFSSGRPDLYIKNLSTGSTV
CCEEEEEEECCCCCEEEECCCCEEEECCCCCCCCCEEEEECCCCCCCCEEEEECCCCCEE
SVKKQGVCISPAWRPGTNECATTLSYEGSQDLYLIRADGTVARRLTRGHSIEVSPSFSPD
EEEECCEEECCCCCCCCCHHHEEEECCCCCCEEEEECCCHHHHHHHCCCEEEECCCCCCC
GSKMAFVSTREGPPQIFIQDLSSGSVRRLTYSGTYNTQPSWSPSGDKILYSSLQKNGEIN
CCEEEEEECCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCEE
IFMINVDGSNLLQLTSGARNNEYPSWSPDGSMIVFSSTRAGSRKLYVMNVDGTNQRPLLN
EEEEEECCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCCCEEC
MKGEQQQPSWSIRN
CCCCCCCCCCCCCC
>Mature Secondary Structure
MKTARISSVRTLIALFCLFMVPFTIRAEEVNEYIAIRKEGSGRISIILDHLKSNGGKESE
CCCCHHHHHHHHHHHHHHHHCCCEEEHHHCCCEEEEEECCCCEEEEEEEEHHCCCCCCHH
WARSLDSTIQGGLDFTGLFNLMPAPLNIRNAQNGALNLGAVRSIGADVFVGGSVTKQSGD
HHHHHHHHHHCCCCEEEHHHCCCCCEEECCCCCCCEEECHHHHCCCCEEECCCEECCCCC
PAMQMQVWDVTGKLLLNRKYSGQDKALRDIGLRFCADLVEMLTGKRSVFGTKMVFVSNST
CEEEEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCC
GQKEIYMCDFDGTNIRQLTNTKSISLTPSVSPDGRFLAWTDFSSGRPDLYIKNLSTGSTV
CCEEEEEEECCCCCEEEECCCCEEEECCCCCCCCCEEEEECCCCCCCCEEEEECCCCCEE
SVKKQGVCISPAWRPGTNECATTLSYEGSQDLYLIRADGTVARRLTRGHSIEVSPSFSPD
EEEECCEEECCCCCCCCCHHHEEEECCCCCCEEEEECCCHHHHHHHCCCEEEECCCCCCC
GSKMAFVSTREGPPQIFIQDLSSGSVRRLTYSGTYNTQPSWSPSGDKILYSSLQKNGEIN
CCEEEEEECCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCEE
IFMINVDGSNLLQLTSGARNNEYPSWSPDGSMIVFSSTRAGSRKLYVMNVDGTNQRPLLN
EEEEEECCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCCCEEC
MKGEQQQPSWSIRN
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]