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The map label for this gene is nadA

Identifier: 193212261

GI number: 193212261

Start: 638641

End: 639609

Strand: Direct

Name: nadA

Synonym: Cpar_0594

Alternate gene names: 193212261

Gene position: 638641-639609 (Clockwise)

Preceding gene: 193212260

Following gene: 193212262

Centisome position: 27.9

GC content: 59.96

Gene sequence:

>969_bases
ATGACCACAGCAAACGATAGACCAGAGGAGGCCTCGAAGCTTTCGACCGAAGAGCTGCTTGAACGGATCGTGGCGCTCAA
GAAAGAGTTGAACGCCGTCATTCTGGCCCACTACTATACCGTCCCGGAAGTTCAGCAGGCGGCGGATATCGTCGGTGACA
GCCTCGCTCTGGCGCGGGCGGCAGAGGATAACTCCGCTGATGTTATCGTGTTCGCGGGCGTCTATTTCATGGCCGAGACG
GCCAAGATTCTCAATCCCGGCAAGCTGGTGCTCATGCCCGACGACCACGCGGGCTGCCCGCTCGCCGACAGTTGCCCCGA
AGCGGAGTTCCGCGCGTTCCGGGAGCAGCATCCCGACGCCATCGCGATCACCTATATCAACTCCACTGCGGCGATCAAAG
CGCTCTCGGACATCACCTGCACCTCCTCGAACGCCGCGCACATCGTCGAGCAGATTCCGCCGGAGCAGAAGATCATCTTT
GGCCCCGACCGCAACCTCGGCACCTGGCTCAGCAAAAAGCTCGATCGCGACATGATTCTCTGGCAGGGCTACTGCTACGT
GCACGACGCCTACTCCGAGGTCTACATGATCCAGGCGATGGCCAAATATCCGGACGCCGAGCTGATCGCCCATCCCGAGT
GCCGCGACGAGGTGCTTCGCCATGCCTCTTTCGTCGGCTCGACGGCCGCGTTACTCGACTACACGGTCAAGAGCCCATCG
CAGAGCTTTATCGTAGCTACCGAGCCGGGCATCCTCTACGAAATGGAGAAGCGCTCGCCTGGCAAGACCTTCATTCCGGC
GCCAAAAGATCCGGCCAATCCGCGCAGCGTCTGCACGCAGATGAAGCAGAACACGCTCGAAAAGCTCTACCTCTGCATGG
TCAACCGCTCACCTGAAATCACGGTCGACGAGAATCTTCGCGAAGCGGCGCTCAAGCCGATCAAGAAGATGCTCGAAATG
TCCGCCTGA

Upstream 100 bases:

>100_bases
CACGCAGCAGTCGGATTGACCACCGTTTCTGTTCTGCGTGATCTTGCTCCTCTTCGTTCGGCGAGGAGTTTTTTTATTCA
TCGCTTTTCATGAAATCGAT

Downstream 100 bases:

>100_bases
CCTTCCGCCGGGCCGCCGCTGGTCCTCAGATGCGCGGCCCGGCAATATTTCCGCGAATCCCTCCTCCATCGTTGCCGACT
CCACATTCCTCTGTGTACCT

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MTTANDRPEEASKLSTEELLERIVALKKELNAVILAHYYTVPEVQQAADIVGDSLALARAAEDNSADVIVFAGVYFMAET
AKILNPGKLVLMPDDHAGCPLADSCPEAEFRAFREQHPDAIAITYINSTAAIKALSDITCTSSNAAHIVEQIPPEQKIIF
GPDRNLGTWLSKKLDRDMILWQGYCYVHDAYSEVYMIQAMAKYPDAELIAHPECRDEVLRHASFVGSTAALLDYTVKSPS
QSFIVATEPGILYEMEKRSPGKTFIPAPKDPANPRSVCTQMKQNTLEKLYLCMVNRSPEITVDENLREAALKPIKKMLEM
SA

Sequences:

>Translated_322_residues
MTTANDRPEEASKLSTEELLERIVALKKELNAVILAHYYTVPEVQQAADIVGDSLALARAAEDNSADVIVFAGVYFMAET
AKILNPGKLVLMPDDHAGCPLADSCPEAEFRAFREQHPDAIAITYINSTAAIKALSDITCTSSNAAHIVEQIPPEQKIIF
GPDRNLGTWLSKKLDRDMILWQGYCYVHDAYSEVYMIQAMAKYPDAELIAHPECRDEVLRHASFVGSTAALLDYTVKSPS
QSFIVATEPGILYEMEKRSPGKTFIPAPKDPANPRSVCTQMKQNTLEKLYLCMVNRSPEITVDENLREAALKPIKKMLEM
SA
>Mature_321_residues
TTANDRPEEASKLSTEELLERIVALKKELNAVILAHYYTVPEVQQAADIVGDSLALARAAEDNSADVIVFAGVYFMAETA
KILNPGKLVLMPDDHAGCPLADSCPEAEFRAFREQHPDAIAITYINSTAAIKALSDITCTSSNAAHIVEQIPPEQKIIFG
PDRNLGTWLSKKLDRDMILWQGYCYVHDAYSEVYMIQAMAKYPDAELIAHPECRDEVLRHASFVGSTAALLDYTVKSPSQ
SFIVATEPGILYEMEKRSPGKTFIPAPKDPANPRSVCTQMKQNTLEKLYLCMVNRSPEITVDENLREAALKPIKKMLEMS
A

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily

Homologues:

Organism=Escherichia coli, GI1786964, Length=313, Percent_Identity=40.8945686900958, Blast_Score=224, Evalue=4e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NADA_CHLP8 (B3QM61)

Other databases:

- EMBL:   CP001099
- RefSeq:   YP_001998214.1
- GeneID:   6419512
- GenomeReviews:   CP001099_GR
- KEGG:   cpc:Cpar_0594
- HOGENOM:   HBG291157
- OMA:   IAHPECE
- ProtClustDB:   PRK09375
- GO:   GO:0005737
- HAMAP:   MF_00568
- InterPro:   IPR003473
- InterPro:   IPR023066
- TIGRFAMs:   TIGR00550

Pfam domain/function: PF02445 NadA

EC number: =2.5.1.72

Molecular weight: Translated: 35652; Mature: 35521

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: BINDING 37-37 BINDING 54-54 BINDING 125-125 BINDING 142-142 BINDING 211-211 BINDING 228-228

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTANDRPEEASKLSTEELLERIVALKKELNAVILAHYYTVPEVQQAADIVGDSLALARA
CCCCCCCCHHHHHCCHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHHCCHHHHHHH
AEDNSADVIVFAGVYFMAETAKILNPGKLVLMPDDHAGCPLADSCPEAEFRAFREQHPDA
CCCCCCCEEEEEHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCE
IAITYINSTAAIKALSDITCTSSNAAHIVEQIPPEQKIIFGPDRNLGTWLSKKLDRDMIL
EEEEEECCHHHHHHHHHCEECCCCHHHHHHHCCCCCEEEECCCCCHHHHHHHHCCCCEEE
WQGYCYVHDAYSEVYMIQAMAKYPDAELIAHPECRDEVLRHASFVGSTAALLDYTVKSPS
EECEEEEEHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHCCHHHHHHHHHCCCC
QSFIVATEPGILYEMEKRSPGKTFIPAPKDPANPRSVCTQMKQNTLEKLYLCMVNRSPEI
CCEEEEECCCEEEEECCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCE
TVDENLREAALKPIKKMLEMSA
EECCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTANDRPEEASKLSTEELLERIVALKKELNAVILAHYYTVPEVQQAADIVGDSLALARA
CCCCCCCHHHHHCCHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHHCCHHHHHHH
AEDNSADVIVFAGVYFMAETAKILNPGKLVLMPDDHAGCPLADSCPEAEFRAFREQHPDA
CCCCCCCEEEEEHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCE
IAITYINSTAAIKALSDITCTSSNAAHIVEQIPPEQKIIFGPDRNLGTWLSKKLDRDMIL
EEEEEECCHHHHHHHHHCEECCCCHHHHHHHCCCCCEEEECCCCCHHHHHHHHCCCCEEE
WQGYCYVHDAYSEVYMIQAMAKYPDAELIAHPECRDEVLRHASFVGSTAALLDYTVKSPS
EECEEEEEHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHCCHHHHHHHHHCCCC
QSFIVATEPGILYEMEKRSPGKTFIPAPKDPANPRSVCTQMKQNTLEKLYLCMVNRSPEI
CCEEEEECCCEEEEECCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCE
TVDENLREAALKPIKKMLEMSA
EECCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA