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The map label for this gene is hprK [H]

Identifier: 193212224

GI number: 193212224

Start: 595613

End: 596644

Strand: Direct

Name: hprK [H]

Synonym: Cpar_0555

Alternate gene names: 193212224

Gene position: 595613-596644 (Clockwise)

Preceding gene: 193212223

Following gene: 193212225

Centisome position: 26.02

GC content: 49.32

Gene sequence:

>1032_bases
ATGAATTTCGACCAGAAGGGACTGAAAAAGCGATCGATTACGGTCGCCTATTTTTTTGAGCATATTGAGAAGCGATTCGA
AATCAGGTTTCGCCGTCTCAACGATGTCGATGAGCAGAATCGGCGAATCTATGAGCGCGATCTGCATCGTCCCGGTCTTG
CCATTGCTGGATTTACCAAGCTTTTTACCTACAAAAGGGTACAGATTCTGGGCAATACCGAGACCCGGTATTTGAATCAC
CTCTCTTCTGAAGAGCGTCGGGCGGCATTTGAAAAATTTGTCAAATTCAAAATGCCGTGCATTATTCTGACCAGCAACAA
CAAGCTCGATCCGGAGCTGATCGACATGGCTGCTGATGCCGGAATTCCGGTGTACGTCACCAGATGTTCATCGACCAGAA
CCATTTATACCATCACCGATTTTCTCGATGAGCAGTTCTCCCAATATCAGCAGTATCACGGTTCTATGGTCGATGTGTAT
GGAGTGGGTGTTCTGTTGGCAGGAAAAAGTGGTTTGGGCAAATCCGAGGTTGCACTCGATCTTATCGAACGAGGTCATGG
CCTGGTGGCCGATGACGTGGTTGTGGTGAAGCGCCGGGGGCAGACCAATACGCTGGTAGCCACACGCAACAACATCATCG
ACCATTTTATGGAGATTCGCGGGTTGGGCGTGGTCGATGTGCGGCAGAATTTCGGTATCAGGGCAATTCGTGATAAAAAA
GTGGTGCAGGTGGTGGTCGAGCTGCTTGAGTGGAGTCAGGAGGCTGAGTATGAACGCCTCGGGCTCGACCAGAAAAGCGT
CAATCTTCTCGGTGTCGATGTGCCGTTGGTACAGCTTCCTATTTTCCCCGGCAAGAACATCACGGTCATCATCGAAGTGG
TGGCTCTGAACTTCCTGTTGAAACGCTATGCAGGGTACGTGGCTGCCGAGGCACTGACCGAGAGAATCAGTAATGTTATG
AACAAAAACCGTAGCGATTCGGCCAGTGGCCCTTTTATCATTCCCGAATATTATGACGATGAAATTGAATAA

Upstream 100 bases:

>100_bases
AAGACAAGCAAAGCACTTTCTGAAATCGGCAATCGCAACAGGGTCAGCACGCTGACCCTGTTGCAGTATCGGGCTTTGCA
AACACCATGATTTCCCGGGC

Downstream 100 bases:

>100_bases
GGCGTTTCATTCACTTTTTCCTGTCGTTCTGCTTGCTGCGGTGACGTTGTTGTCGGCCTGCTCGAAGTCAGGTGGCAAAA
ATGCAGCTCTCTCGGCGGCG

Product: HPr kinase/phosphorylase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase [H]

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MNFDQKGLKKRSITVAYFFEHIEKRFEIRFRRLNDVDEQNRRIYERDLHRPGLAIAGFTKLFTYKRVQILGNTETRYLNH
LSSEERRAAFEKFVKFKMPCIILTSNNKLDPELIDMAADAGIPVYVTRCSSTRTIYTITDFLDEQFSQYQQYHGSMVDVY
GVGVLLAGKSGLGKSEVALDLIERGHGLVADDVVVVKRRGQTNTLVATRNNIIDHFMEIRGLGVVDVRQNFGIRAIRDKK
VVQVVVELLEWSQEAEYERLGLDQKSVNLLGVDVPLVQLPIFPGKNITVIIEVVALNFLLKRYAGYVAAEALTERISNVM
NKNRSDSASGPFIIPEYYDDEIE

Sequences:

>Translated_343_residues
MNFDQKGLKKRSITVAYFFEHIEKRFEIRFRRLNDVDEQNRRIYERDLHRPGLAIAGFTKLFTYKRVQILGNTETRYLNH
LSSEERRAAFEKFVKFKMPCIILTSNNKLDPELIDMAADAGIPVYVTRCSSTRTIYTITDFLDEQFSQYQQYHGSMVDVY
GVGVLLAGKSGLGKSEVALDLIERGHGLVADDVVVVKRRGQTNTLVATRNNIIDHFMEIRGLGVVDVRQNFGIRAIRDKK
VVQVVVELLEWSQEAEYERLGLDQKSVNLLGVDVPLVQLPIFPGKNITVIIEVVALNFLLKRYAGYVAAEALTERISNVM
NKNRSDSASGPFIIPEYYDDEIE
>Mature_343_residues
MNFDQKGLKKRSITVAYFFEHIEKRFEIRFRRLNDVDEQNRRIYERDLHRPGLAIAGFTKLFTYKRVQILGNTETRYLNH
LSSEERRAAFEKFVKFKMPCIILTSNNKLDPELIDMAADAGIPVYVTRCSSTRTIYTITDFLDEQFSQYQQYHGSMVDVY
GVGVLLAGKSGLGKSEVALDLIERGHGLVADDVVVVKRRGQTNTLVATRNNIIDHFMEIRGLGVVDVRQNFGIRAIRDKK
VVQVVVELLEWSQEAEYERLGLDQKSVNLLGVDVPLVQLPIFPGKNITVIIEVVALNFLLKRYAGYVAAEALTERISNVM
NKNRSDSASGPFIIPEYYDDEIE

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126 [H]

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N [H]

EC number: NA

Molecular weight: Translated: 39206; Mature: 39206

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFDQKGLKKRSITVAYFFEHIEKRFEIRFRRLNDVDEQNRRIYERDLHRPGLAIAGFTK
CCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHH
LFTYKRVQILGNTETRYLNHLSSEERRAAFEKFVKFKMPCIILTSNNKLDPELIDMAADA
HHHHHEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCC
GIPVYVTRCSSTRTIYTITDFLDEQFSQYQQYHGSMVDVYGVGVLLAGKSGLGKSEVALD
CCCEEEEECCCCCEEEEHHHHHHHHHHHHHHHCCCEEEEEECEEEEECCCCCCHHHHHHH
LIERGHGLVADDVVVVKRRGQTNTLVATRNNIIDHFMEIRGLGVVDVRQNFGIRAIRDKK
HHHCCCCCEECCEEEEEECCCCCEEEEEHHHHHHHHHHHHCCCEEEECCCCCCEEECHHH
VVQVVVELLEWSQEAEYERLGLDQKSVNLLGVDVPLVQLPIFPGKNITVIIEVVALNFLL
HHHHHHHHHHCCCCCCHHHHCCCCCCCEEEEECCCEEEECCCCCCCCEEHHHHHHHHHHH
KRYAGYVAAEALTERISNVMNKNRSDSASGPFIIPEYYDDEIE
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCC
>Mature Secondary Structure
MNFDQKGLKKRSITVAYFFEHIEKRFEIRFRRLNDVDEQNRRIYERDLHRPGLAIAGFTK
CCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHH
LFTYKRVQILGNTETRYLNHLSSEERRAAFEKFVKFKMPCIILTSNNKLDPELIDMAADA
HHHHHEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCC
GIPVYVTRCSSTRTIYTITDFLDEQFSQYQQYHGSMVDVYGVGVLLAGKSGLGKSEVALD
CCCEEEEECCCCCEEEEHHHHHHHHHHHHHHHCCCEEEEEECEEEEECCCCCCHHHHHHH
LIERGHGLVADDVVVVKRRGQTNTLVATRNNIIDHFMEIRGLGVVDVRQNFGIRAIRDKK
HHHCCCCCEECCEEEEEECCCCCEEEEEHHHHHHHHHHHHCCCEEEECCCCCCEEECHHH
VVQVVVELLEWSQEAEYERLGLDQKSVNLLGVDVPLVQLPIFPGKNITVIIEVVALNFLL
HHHHHHHHHHCCCCCCHHHHCCCCCCCEEEEECCCEEEECCCCCCCCEEHHHHHHHHHHH
KRYAGYVAAEALTERISNVMNKNRSDSASGPFIIPEYYDDEIE
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]