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The map label for this gene is recG [H]

Identifier: 193212054

GI number: 193212054

Start: 407480

End: 409612

Strand: Direct

Name: recG [H]

Synonym: Cpar_0384

Alternate gene names: 193212054

Gene position: 407480-409612 (Clockwise)

Preceding gene: 193212048

Following gene: 193212055

Centisome position: 17.8

GC content: 64.7

Gene sequence:

>2133_bases
ATGCCCTCATCGTCAGTCCCAATTTCATCGTTGCAGAGCATCAAGGGGGTCGGGCCGAAGCGCGCGGCAGTTCTGGCGGA
GGCGGGTATCCGGTCGGTTGCCGACCTGTACGACTATTTTCCGCGCCGCTACCTCGACCGCACCGTCATCCGGCGTATTG
CCCAGCTTCGCGACGGCGAGTCGGTGACGGTGGTGGGCACGGTGACCGGCACGCGGCTCGAAGGCGGGGGGCGCGGACGG
GGGCGCTTCAAGGCGACCGTTAGTGACGGTTCGGGCGTGCTGGAGCTGACCTGGTTCCGGTCGGTGCACTACTTTTCAAA
AAGCATCCACAGCGGCGACATGCTTGCCGTGCATGGCCGCGTGAGTTTTTTCGGGCGCACGCCGGGGATGCAGCACCCCG
ACTACGACCGGCTCGGCGGCAGCGGAGAAGATGGCCGCGCGGAGGGGTCGGCGGACGGCGAGCTGTACAAAACCGGCGGC
ATCATTCCGCTCTACCCGACAAGCGACGCCATGAAGCAAGGCGGCGTCAATTCGGGGACGCTCCGTGCGATCGTACATCG
GGCGTTCCGCGACCAGCCGCCGCGCATCACAGAATATCTCACTCCTGAAATCATGGAGGCGTACGGGCTGATGCCCATCG
GCGAGGCGTACCGGCAACTCCATTTTCCCGATTCCGCCGAGCTGCTCGAACGGGCGCGCTACCGCATGAAGTGGAGCGAG
CTTTTTTTCGCACAGCTCTTTTTCGCCCTGCGCCGCACCGAGGAGCGCCGGAGCCTCACCTCGGCGCGATTCGAGCGCTC
GGGCGACAAGACTGCCGGGCTGCACGAACGGTTGCCGTTCGAGATGACCGGCGACCAGAAACGCGCCGTCAAGGAGATTT
ACCACGACCTGCGCAGCGGCCACCAGATGAACCGCCTGGTGCAGGGCGACGTCGGTTCGGGCAAGACGCTCGTGGCGCAG
TTCGCGATGACGCTCGCCGTGGACAACGGTTTGCAGGCGGCCTTTATGGCGCCGACCGAAATCCTCGCCTTCCAGCACTA
CATCGGCCTGAAGCAGGTGCTCGAACCGCTCGGCGTGACGGTTGCGCTGCTGACCGGTCGCCAGAAGAAAAAGCTGCGCG
AGGAGCAGCTTGCCCGGCTCGAAAGCGGCGAAATCGACATCGCGGTCGGCACGCACGCCATCATCGAGGCCGGGGTGCGG
TTCCGGCGGCTCGGGCTGGCGATCATCGACGAGCAGCACCGCTTCGGCGTGATGCAGCGCAAGGCGTTGCAGGACAAGGC
CGAGAATCCGCACGTGCTGCTCATGACCGCCACACCGATTCCGCGCACGCTGACGATGGGCATCTACGGCGACCTCGACG
TGTCGATCATCGCTGAAATGCCCGCCGGACGCCAGCCGATCCAGACGCGACTCTGCCGCGAAGATCAAAAACCGGAGCTT
TATCGTCTCTTGCGGAAGCAAATTGCCGAGGGGCGGCAGGCGTACATCGTCTATCCGCTGGTCGAAGAGTCGGAGAAGAT
GGATCTGAAGGCGGCTACCGAGAGCTACGAGCAGCTCCGGGGCGAAGTGTTTCCGGAGTTGCGTTTGGGGCTGATCCACG
GCAAGCTCCCGGCTGAGGAGAAGGAGGCGGTGATGGCGGCATTCCGCAGCGGCGAACTCGACATCCTTGTCGGCACGACC
GTGATCGAGGTCGGCGTCGATGTGCCCAACGCCACGGTGATGGTGATCGAGCACGCTGAGCGGTTCGGCATTTCGCAGCT
CCATCAGCTTCGCGGGCGCGTGGGGCGCGGCACGCATCGCTCCTCGTGCTACCTCGTCTATGCCAAAATGGCTGGCGACG
CCAAGGAGCGGTTGCAGGCGATGGCTGCGACCAACGACGGATTCCGGCTCTCAGAGATCGACCTCCAGCTTCGCGGCGCA
GGCAACATGCTCGGCCGCGAGCAGTCGGGCACGGCGAGCAGTCTCAGAATCGCCGACCTGATGACCGACGGCGAGATCAT
GCGCTCCGCGCGTGCGGCGGCGTTCGAGTTGGTCGAAAAGGATGAAACGCTTTCGCATCCCGAACACGCTCGGCTCCGCG
ACTACTACCACACCCACTTCCGGAAGCGCATCTCGCTCGCCGACGTGGGGTGA

Upstream 100 bases:

>100_bases
TCATGATCCTTTAGGATTTCGTTGCCTTGGTGACAATAAACAATTGACCCGAAATAAAGGGATTTTTCCGCTAATAACCA
AGCCGATACGGTAATTCCTC

Downstream 100 bases:

>100_bases
GGTGGAGAGGGATTCTTCTCGGTCATTGAAATCGGCGACTTCGTCGGCGGTAATTGCGTTTTAGTAGGGGCGATCCCTTG
CGGTCGCCCTGTTACGTTTT

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 710; Mature: 709

Protein sequence:

>710_residues
MPSSSVPISSLQSIKGVGPKRAAVLAEAGIRSVADLYDYFPRRYLDRTVIRRIAQLRDGESVTVVGTVTGTRLEGGGRGR
GRFKATVSDGSGVLELTWFRSVHYFSKSIHSGDMLAVHGRVSFFGRTPGMQHPDYDRLGGSGEDGRAEGSADGELYKTGG
IIPLYPTSDAMKQGGVNSGTLRAIVHRAFRDQPPRITEYLTPEIMEAYGLMPIGEAYRQLHFPDSAELLERARYRMKWSE
LFFAQLFFALRRTEERRSLTSARFERSGDKTAGLHERLPFEMTGDQKRAVKEIYHDLRSGHQMNRLVQGDVGSGKTLVAQ
FAMTLAVDNGLQAAFMAPTEILAFQHYIGLKQVLEPLGVTVALLTGRQKKKLREEQLARLESGEIDIAVGTHAIIEAGVR
FRRLGLAIIDEQHRFGVMQRKALQDKAENPHVLLMTATPIPRTLTMGIYGDLDVSIIAEMPAGRQPIQTRLCREDQKPEL
YRLLRKQIAEGRQAYIVYPLVEESEKMDLKAATESYEQLRGEVFPELRLGLIHGKLPAEEKEAVMAAFRSGELDILVGTT
VIEVGVDVPNATVMVIEHAERFGISQLHQLRGRVGRGTHRSSCYLVYAKMAGDAKERLQAMAATNDGFRLSEIDLQLRGA
GNMLGREQSGTASSLRIADLMTDGEIMRSARAAAFELVEKDETLSHPEHARLRDYYHTHFRKRISLADVG

Sequences:

>Translated_710_residues
MPSSSVPISSLQSIKGVGPKRAAVLAEAGIRSVADLYDYFPRRYLDRTVIRRIAQLRDGESVTVVGTVTGTRLEGGGRGR
GRFKATVSDGSGVLELTWFRSVHYFSKSIHSGDMLAVHGRVSFFGRTPGMQHPDYDRLGGSGEDGRAEGSADGELYKTGG
IIPLYPTSDAMKQGGVNSGTLRAIVHRAFRDQPPRITEYLTPEIMEAYGLMPIGEAYRQLHFPDSAELLERARYRMKWSE
LFFAQLFFALRRTEERRSLTSARFERSGDKTAGLHERLPFEMTGDQKRAVKEIYHDLRSGHQMNRLVQGDVGSGKTLVAQ
FAMTLAVDNGLQAAFMAPTEILAFQHYIGLKQVLEPLGVTVALLTGRQKKKLREEQLARLESGEIDIAVGTHAIIEAGVR
FRRLGLAIIDEQHRFGVMQRKALQDKAENPHVLLMTATPIPRTLTMGIYGDLDVSIIAEMPAGRQPIQTRLCREDQKPEL
YRLLRKQIAEGRQAYIVYPLVEESEKMDLKAATESYEQLRGEVFPELRLGLIHGKLPAEEKEAVMAAFRSGELDILVGTT
VIEVGVDVPNATVMVIEHAERFGISQLHQLRGRVGRGTHRSSCYLVYAKMAGDAKERLQAMAATNDGFRLSEIDLQLRGA
GNMLGREQSGTASSLRIADLMTDGEIMRSARAAAFELVEKDETLSHPEHARLRDYYHTHFRKRISLADVG
>Mature_709_residues
PSSSVPISSLQSIKGVGPKRAAVLAEAGIRSVADLYDYFPRRYLDRTVIRRIAQLRDGESVTVVGTVTGTRLEGGGRGRG
RFKATVSDGSGVLELTWFRSVHYFSKSIHSGDMLAVHGRVSFFGRTPGMQHPDYDRLGGSGEDGRAEGSADGELYKTGGI
IPLYPTSDAMKQGGVNSGTLRAIVHRAFRDQPPRITEYLTPEIMEAYGLMPIGEAYRQLHFPDSAELLERARYRMKWSEL
FFAQLFFALRRTEERRSLTSARFERSGDKTAGLHERLPFEMTGDQKRAVKEIYHDLRSGHQMNRLVQGDVGSGKTLVAQF
AMTLAVDNGLQAAFMAPTEILAFQHYIGLKQVLEPLGVTVALLTGRQKKKLREEQLARLESGEIDIAVGTHAIIEAGVRF
RRLGLAIIDEQHRFGVMQRKALQDKAENPHVLLMTATPIPRTLTMGIYGDLDVSIIAEMPAGRQPIQTRLCREDQKPELY
RLLRKQIAEGRQAYIVYPLVEESEKMDLKAATESYEQLRGEVFPELRLGLIHGKLPAEEKEAVMAAFRSGELDILVGTTV
IEVGVDVPNATVMVIEHAERFGISQLHQLRGRVGRGTHRSSCYLVYAKMAGDAKERLQAMAATNDGFRLSEIDLQLRGAG
NMLGREQSGTASSLRIADLMTDGEIMRSARAAAFELVEKDETLSHPEHARLRDYYHTHFRKRISLADVG

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=687, Percent_Identity=41.4847161572052, Blast_Score=432, Evalue=1e-122,
Organism=Escherichia coli, GI1787357, Length=398, Percent_Identity=39.4472361809045, Blast_Score=276, Evalue=5e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 79005; Mature: 78873

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: PS00185 IPNS_1 ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSSSVPISSLQSIKGVGPKRAAVLAEAGIRSVADLYDYFPRRYLDRTVIRRIAQLRDGE
CCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SVTVVGTVTGTRLEGGGRGRGRFKATVSDGSGVLELTWFRSVHYFSKSIHSGDMLAVHGR
EEEEEEEEECEEECCCCCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHCCCCCEEEEECE
VSFFGRTPGMQHPDYDRLGGSGEDGRAEGSADGELYKTGGIIPLYPTSDAMKQGGVNSGT
EEEEECCCCCCCCCHHHCCCCCCCCCCCCCCCCCEEECCCEEEECCCHHHHHHCCCCCHH
LRAIVHRAFRDQPPRITEYLTPEIMEAYGLMPIGEAYRQLHFPDSAELLERARYRMKWSE
HHHHHHHHHHCCCCCHHHHCCHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LFFAQLFFALRRTEERRSLTSARFERSGDKTAGLHERLPFEMTGDQKRAVKEIYHDLRSG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHCC
HQMNRLVQGDVGSGKTLVAQFAMTLAVDNGLQAAFMAPTEILAFQHYIGLKQVLEPLGVT
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCE
VALLTGRQKKKLREEQLARLESGEIDIAVGTHAIIEAGVRFRRLGLAIIDEQHRFGVMQR
EEEECCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHCHHHHHHCHHEECCHHHHHHHHH
KALQDKAENPHVLLMTATPIPRTLTMGIYGDLDVSIIAEMPAGRQPIQTRLCREDQKPEL
HHHHHCCCCCEEEEEECCCCCCEEEECEECCCCEEEEECCCCCCCHHHHHHHCCCCCCHH
YRLLRKQIAEGRQAYIVYPLVEESEKMDLKAATESYEQLRGEVFPELRLGLIHGKLPAEE
HHHHHHHHHCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCHH
KEAVMAAFRSGELDILVGTTVIEVGVDVPNATVMVIEHAERFGISQLHQLRGRVGRGTHR
HHHHHHHHCCCCEEEEECCEEEEECCCCCCCEEEEEECHHHCCHHHHHHHHHHCCCCCCC
SSCYLVYAKMAGDAKERLQAMAATNDGFRLSEIDLQLRGAGNMLGREQSGTASSLRIADL
CCEEEEEEECCCCHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCEEHHHH
MTDGEIMRSARAAAFELVEKDETLSHPEHARLRDYYHTHFRKRISLADVG
HCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PSSSVPISSLQSIKGVGPKRAAVLAEAGIRSVADLYDYFPRRYLDRTVIRRIAQLRDGE
CCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SVTVVGTVTGTRLEGGGRGRGRFKATVSDGSGVLELTWFRSVHYFSKSIHSGDMLAVHGR
EEEEEEEEECEEECCCCCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHCCCCCEEEEECE
VSFFGRTPGMQHPDYDRLGGSGEDGRAEGSADGELYKTGGIIPLYPTSDAMKQGGVNSGT
EEEEECCCCCCCCCHHHCCCCCCCCCCCCCCCCCEEECCCEEEECCCHHHHHHCCCCCHH
LRAIVHRAFRDQPPRITEYLTPEIMEAYGLMPIGEAYRQLHFPDSAELLERARYRMKWSE
HHHHHHHHHHCCCCCHHHHCCHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LFFAQLFFALRRTEERRSLTSARFERSGDKTAGLHERLPFEMTGDQKRAVKEIYHDLRSG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHCC
HQMNRLVQGDVGSGKTLVAQFAMTLAVDNGLQAAFMAPTEILAFQHYIGLKQVLEPLGVT
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCE
VALLTGRQKKKLREEQLARLESGEIDIAVGTHAIIEAGVRFRRLGLAIIDEQHRFGVMQR
EEEECCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHCHHHHHHCHHEECCHHHHHHHHH
KALQDKAENPHVLLMTATPIPRTLTMGIYGDLDVSIIAEMPAGRQPIQTRLCREDQKPEL
HHHHHCCCCCEEEEEECCCCCCEEEECEECCCCEEEEECCCCCCCHHHHHHHCCCCCCHH
YRLLRKQIAEGRQAYIVYPLVEESEKMDLKAATESYEQLRGEVFPELRLGLIHGKLPAEE
HHHHHHHHHCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCHH
KEAVMAAFRSGELDILVGTTVIEVGVDVPNATVMVIEHAERFGISQLHQLRGRVGRGTHR
HHHHHHHHCCCCEEEEECCEEEEECCCCCCCEEEEEECHHHCCHHHHHHHHHHCCCCCCC
SSCYLVYAKMAGDAKERLQAMAATNDGFRLSEIDLQLRGAGNMLGREQSGTASSLRIADL
CCEEEEEEECCCCHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCEEHHHH
MTDGEIMRSARAAAFELVEKDETLSHPEHARLRDYYHTHFRKRISLADVG
HCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]