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The map label for this gene is arsA1 [H]

Identifier: 193211947

GI number: 193211947

Start: 292154

End: 293308

Strand: Direct

Name: arsA1 [H]

Synonym: Cpar_0273

Alternate gene names: 193211947

Gene position: 292154-293308 (Clockwise)

Preceding gene: 193211946

Following gene: 193211950

Centisome position: 12.76

GC content: 54.46

Gene sequence:

>1155_bases
ATGAGAATCATTCTTTACCTGGGCAAAGGCGGCGTGGGCAAGACCACCGTTTCCGCTTCCACAGCGACAGCGATCGCTCG
CAGCGGCAAGCGCGTGCTGATCATGAGTACCGATGTGGCCCACAGTCTTGCTGATGCGTTCGGCGTTGAGTTGAGCTCGA
CCCCTCTTGAGGTCGAGAAAAACCTTTTTGCCATGGAGGTGAACGTTCTTGCAGAAATCAGGGAAAACTGGACCGAACTG
TACTCCTACTTCTCCTCGATTCTCATGCATGACGGCGCGAACGAAATCGTCGCCGAAGAGCTTGCCATCGTGCCTGGCAT
GGAGGAGATGATCAGCCTTCGCTACATCTGGAAAGCGGCCAAGTCCGGCAAGTACGATGCTGTCGTGGTTGATGCCGCTC
CAACCGGCGAGACGATGCGCCTGCTCGGTATGCCGGAGTCCTACGGCTGGTACTCCGAAAAGATCGGCGGCTGGCACTCG
AAAGCGATCGGTTTTGCCGCTCCGCTGCTCACCAAGTTCATGCCGAAGAAGAACATCTTCAAGCTCATGCCCGAGGTCAA
CGATCACATGAAGGAGCTGCACGGTATGTTGCAGGACAAGAGCATTACGACCTTCAGGGTGGTGCTCAATCCGGAGAACA
TGGTTATCAAGGAGGCTCTGCGCGTCCAGACCTACCTCAACCTGTTCGGTTACAAACTCGATGCTGCCGTGGTCAACAAG
GTGCTCCCTCAGAATTCAAGCGACCCGTACCTGCAGAGCCTCATCGACCAGCAGGCCAAGTACCTCAGGGTGATCGACAA
CTGCTTCTATCCTGTCCCGATTTTCAAGGCCAAGCAGTCTCCCAAAGAGGTCATCAATCCCGACAGGTTGTATGATCTGA
GCCAGGAGCTGTTCGATGGTCGTAATCCGATTGATGTACTCTACACCAACGATCGTACCCAGACGCTTGAGAAGATCGAC
GGCAAGTACGTACTCAGCCTCTACCTGCCTAACGTCGAGGTTGAAAAGCTTGCGGTCAACATCAAAGGCGACGAGTTGCT
GGTCGATATCAACAACTTCCGCAAGAGCATCGTGCTGCCTAACGTGCTGGTTGGTCGCAAAACCGAAGGCGCCGATTTCG
AGCAGGGAATGCTGAATATCACGTTCTCGAACTGA

Upstream 100 bases:

>100_bases
GGCCGGAGCAAACGGCGGGGGAGAAAAGTCTGACGGCCAAAAGCCGACGGGAGAAAGACATTCAGTTTAAGTCAAGTTTT
CACCATAGTTTTTCAACACC

Downstream 100 bases:

>100_bases
TTCTTACGGAACGCTTGAGCTTTTATGGCGGGTCGCTTTACGGTGGCCCGCTTTTTTTGTTTCCGAAGGATGCGTTGGCG
GTACGAGTGGAAGAAAAAGC

Product: arsenite-activated ATPase ArsA

Products: NA

Alternate protein names: Arsenical resistance ATPase 1; Arsenite-translocating ATPase 1; Arsenite-transporting ATPase 1 [H]

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MRIILYLGKGGVGKTTVSASTATAIARSGKRVLIMSTDVAHSLADAFGVELSSTPLEVEKNLFAMEVNVLAEIRENWTEL
YSYFSSILMHDGANEIVAEELAIVPGMEEMISLRYIWKAAKSGKYDAVVVDAAPTGETMRLLGMPESYGWYSEKIGGWHS
KAIGFAAPLLTKFMPKKNIFKLMPEVNDHMKELHGMLQDKSITTFRVVLNPENMVIKEALRVQTYLNLFGYKLDAAVVNK
VLPQNSSDPYLQSLIDQQAKYLRVIDNCFYPVPIFKAKQSPKEVINPDRLYDLSQELFDGRNPIDVLYTNDRTQTLEKID
GKYVLSLYLPNVEVEKLAVNIKGDELLVDINNFRKSIVLPNVLVGRKTEGADFEQGMLNITFSN

Sequences:

>Translated_384_residues
MRIILYLGKGGVGKTTVSASTATAIARSGKRVLIMSTDVAHSLADAFGVELSSTPLEVEKNLFAMEVNVLAEIRENWTEL
YSYFSSILMHDGANEIVAEELAIVPGMEEMISLRYIWKAAKSGKYDAVVVDAAPTGETMRLLGMPESYGWYSEKIGGWHS
KAIGFAAPLLTKFMPKKNIFKLMPEVNDHMKELHGMLQDKSITTFRVVLNPENMVIKEALRVQTYLNLFGYKLDAAVVNK
VLPQNSSDPYLQSLIDQQAKYLRVIDNCFYPVPIFKAKQSPKEVINPDRLYDLSQELFDGRNPIDVLYTNDRTQTLEKID
GKYVLSLYLPNVEVEKLAVNIKGDELLVDINNFRKSIVLPNVLVGRKTEGADFEQGMLNITFSN
>Mature_384_residues
MRIILYLGKGGVGKTTVSASTATAIARSGKRVLIMSTDVAHSLADAFGVELSSTPLEVEKNLFAMEVNVLAEIRENWTEL
YSYFSSILMHDGANEIVAEELAIVPGMEEMISLRYIWKAAKSGKYDAVVVDAAPTGETMRLLGMPESYGWYSEKIGGWHS
KAIGFAAPLLTKFMPKKNIFKLMPEVNDHMKELHGMLQDKSITTFRVVLNPENMVIKEALRVQTYLNLFGYKLDAAVVNK
VLPQNSSDPYLQSLIDQQAKYLRVIDNCFYPVPIFKAKQSPKEVINPDRLYDLSQELFDGRNPIDVLYTNDRTQTLEKID
GKYVLSLYLPNVEVEKLAVNIKGDELLVDINNFRKSIVLPNVLVGRKTEGADFEQGMLNITFSN

Specific function: Anion-transporting ATPase. Catalyzes the extrusion of arsenite [H]

COG id: COG0003

COG function: function code P; Oxyanion-translocating ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arsA ATPase family [H]

Homologues:

Organism=Homo sapiens, GI50428938, Length=299, Percent_Identity=25.4180602006689, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17557003, Length=310, Percent_Identity=25.8064516129032, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320103, Length=315, Percent_Identity=26.031746031746, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24586297, Length=307, Percent_Identity=29.9674267100977, Blast_Score=99, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003348 [H]

Pfam domain/function: NA

EC number: =3.6.3.16 [H]

Molecular weight: Translated: 43060; Mature: 43060

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIILYLGKGGVGKTTVSASTATAIARSGKRVLIMSTDVAHSLADAFGVELSSTPLEVEK
CEEEEEECCCCCCCEEECHHHHHHHHHCCCEEEEEECHHHHHHHHHHCCCCCCCCHHHHC
NLFAMEVNVLAEIRENWTELYSYFSSILMHDGANEIVAEELAIVPGMEEMISLRYIWKAA
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
KSGKYDAVVVDAAPTGETMRLLGMPESYGWYSEKIGGWHSKAIGFAAPLLTKFMPKKNIF
CCCCCCEEEEECCCCCCCEEEEECCCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCHHHH
KLMPEVNDHMKELHGMLQDKSITTFRVVLNPENMVIKEALRVQTYLNLFGYKLDAAVVNK
HHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VLPQNSSDPYLQSLIDQQAKYLRVIDNCFYPVPIFKAKQSPKEVINPDRLYDLSQELFDG
HCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHCC
RNPIDVLYTNDRTQTLEKIDGKYVLSLYLPNVEVEKLAVNIKGDELLVDINNFRKSIVLP
CCCEEEEEECCHHHHHHHCCCEEEEEEECCCCEEEEEEEEECCCEEEEEHHHHHHHHCCC
NVLVGRKTEGADFEQGMLNITFSN
CCEECCCCCCCCCCCCEEEEEECC
>Mature Secondary Structure
MRIILYLGKGGVGKTTVSASTATAIARSGKRVLIMSTDVAHSLADAFGVELSSTPLEVEK
CEEEEEECCCCCCCEEECHHHHHHHHHCCCEEEEEECHHHHHHHHHHCCCCCCCCHHHHC
NLFAMEVNVLAEIRENWTELYSYFSSILMHDGANEIVAEELAIVPGMEEMISLRYIWKAA
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
KSGKYDAVVVDAAPTGETMRLLGMPESYGWYSEKIGGWHSKAIGFAAPLLTKFMPKKNIF
CCCCCCEEEEECCCCCCCEEEEECCCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCHHHH
KLMPEVNDHMKELHGMLQDKSITTFRVVLNPENMVIKEALRVQTYLNLFGYKLDAAVVNK
HHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VLPQNSSDPYLQSLIDQQAKYLRVIDNCFYPVPIFKAKQSPKEVINPDRLYDLSQELFDG
HCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHCC
RNPIDVLYTNDRTQTLEKIDGKYVLSLYLPNVEVEKLAVNIKGDELLVDINNFRKSIVLP
CCCEEEEEECCHHHHHHHCCCEEEEEEECCCCEEEEEEEEECCCEEEEEHHHHHHHHCCC
NVLVGRKTEGADFEQGMLNITFSN
CCEECCCCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]