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The map label for this gene is amt [H]

Identifier: 193211763

GI number: 193211763

Start: 101356

End: 102693

Strand: Direct

Name: amt [H]

Synonym: Cpar_0088

Alternate gene names: 193211763

Gene position: 101356-102693 (Clockwise)

Preceding gene: 193211761

Following gene: 193211764

Centisome position: 4.43

GC content: 57.32

Gene sequence:

>1338_bases
ATGTTTATGGGTAACAAACTGAGATCATCACTGCTTGTTCTGTTTGCGCTGATGATGGCTCACAATACCGGATGGGCTGC
CGAAAGTGTGACTTCGGATACCGGTACGACGTCATGGATGCTGACTTCCACGGCACTGGTGTTGCTGATGGTGCCAGGTC
TGGCCATGTTCTATGGTGGCCTTGTCCGGACGAAAAACGTTCTTGGTACCATGATGCACAGCTTTGCCGCTATGGTGATT
ATCGGCGTGATCTGGCCTGCGGTGGGTTATGCGCTGAGCTTTGGCCCCAATATTCTTGGTGGACTGGTTGGCTGGAACAG
CGACTATTTCATGTTGCAGGGTATCGATAACGCGATTATGGACAGCCATATTCCTGAATATGTATTCGCCATGTTCCAGG
GCAAGTTTGCCATCATCACTCCGGCGCTGATTGCCGGTGCGTTTGCCGAGCGTGTCAATTTCAAGGGCTACCTTCTGTTC
ATCGCGCTCTGGAGCATCGTGGTCTATACGCCGATCTGCCACTGGGTGTGGGCTGCTGACGGCTTTCTGTTCAACCTCGG
TGCTGCCGGTGCGATCGACTTCGCAGGTGGCACGGTGGTTCATATTTCGTCCGGTGTTACGGCGCTGGTTGCCGCGCTGT
ACCTCGGCGCCCGCCGTGGTTACCCGAGGAATGTGATGCATCCGAACAATCTGGTCATGACCCTGATGGGCGCCGGTCTG
CTTTGGGTTGGCTGGTTCGGCTTCAACGCCGGCAGCGCCATTTCGAGCGATCTTGCCACCGCCCGTGCCCTGACCGTGAC
CCAGATGGCCGCCGCTGCCGGTGCGTTCACCTGGATGATGGTTGAGCTCGTTCACTACGGCAAGGCCACCAGTCTTGGCG
TGGCATCGGGCATTCTTGCCGGTCTGGTTGCAATCACTCCGGCCGCCGGGGTTGTGCCGCCTTTCGGTGCATTCGCGCTG
GGCGCCATTGCTGCTCTGATCTGCTACATGGCCATTACGCTCAAAAACAAGCTCGGTTACGATGACAGCCTCGATGCGTT
CGGCGTGCACGGTGTCGGTGGTATTGTCGGCGCTCTTTTCCTCACCTTTTTCATTCGTCCCTCCTGGATGGCCGAGGCTG
CTGAAGCTGCCGGCGGTTCCTGGACGGTGTGGCAGCAGCTCGGTGTTCAGGCTACGGCGGTGGGCGTTACGGTGGTGTTT
GCCGCTGTCGTTTCGCTGGTGCTGCTGGTGATTGTGGAAAAAACCGTCGGTTTGCGTATCGGCGAAAGCGATGAAATGTC
CGGCCTTGACCACAGCATGCACGGTGAGCAGGGATACGGCCTTATCAATCCTAACTGA

Upstream 100 bases:

>100_bases
GTAAGAAAGTTGCTTGTAATTCTTGTTTCGCCTTAAATGAATCGTTATTATCAACACTCATTCATAAAATTTTTAGGATT
TATTAATCGAATAAGACGGG

Downstream 100 bases:

>100_bases
TAGAAAACAGTATGAAACTTATTACCGCTATCATTCCTCCGGACAGGCTTGACCACGTTCGCGAAGCGCTGATACAGGCC
GATATTACCAGAATTACGGT

Product: ammonium transporter

Products: NH3 [Cytoplasm] [C]

Alternate protein names: Ammonia transporter [H]

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MFMGNKLRSSLLVLFALMMAHNTGWAAESVTSDTGTTSWMLTSTALVLLMVPGLAMFYGGLVRTKNVLGTMMHSFAAMVI
IGVIWPAVGYALSFGPNILGGLVGWNSDYFMLQGIDNAIMDSHIPEYVFAMFQGKFAIITPALIAGAFAERVNFKGYLLF
IALWSIVVYTPICHWVWAADGFLFNLGAAGAIDFAGGTVVHISSGVTALVAALYLGARRGYPRNVMHPNNLVMTLMGAGL
LWVGWFGFNAGSAISSDLATARALTVTQMAAAAGAFTWMMVELVHYGKATSLGVASGILAGLVAITPAAGVVPPFGAFAL
GAIAALICYMAITLKNKLGYDDSLDAFGVHGVGGIVGALFLTFFIRPSWMAEAAEAAGGSWTVWQQLGVQATAVGVTVVF
AAVVSLVLLVIVEKTVGLRIGESDEMSGLDHSMHGEQGYGLINPN

Sequences:

>Translated_445_residues
MFMGNKLRSSLLVLFALMMAHNTGWAAESVTSDTGTTSWMLTSTALVLLMVPGLAMFYGGLVRTKNVLGTMMHSFAAMVI
IGVIWPAVGYALSFGPNILGGLVGWNSDYFMLQGIDNAIMDSHIPEYVFAMFQGKFAIITPALIAGAFAERVNFKGYLLF
IALWSIVVYTPICHWVWAADGFLFNLGAAGAIDFAGGTVVHISSGVTALVAALYLGARRGYPRNVMHPNNLVMTLMGAGL
LWVGWFGFNAGSAISSDLATARALTVTQMAAAAGAFTWMMVELVHYGKATSLGVASGILAGLVAITPAAGVVPPFGAFAL
GAIAALICYMAITLKNKLGYDDSLDAFGVHGVGGIVGALFLTFFIRPSWMAEAAEAAGGSWTVWQQLGVQATAVGVTVVF
AAVVSLVLLVIVEKTVGLRIGESDEMSGLDHSMHGEQGYGLINPN
>Mature_445_residues
MFMGNKLRSSLLVLFALMMAHNTGWAAESVTSDTGTTSWMLTSTALVLLMVPGLAMFYGGLVRTKNVLGTMMHSFAAMVI
IGVIWPAVGYALSFGPNILGGLVGWNSDYFMLQGIDNAIMDSHIPEYVFAMFQGKFAIITPALIAGAFAERVNFKGYLLF
IALWSIVVYTPICHWVWAADGFLFNLGAAGAIDFAGGTVVHISSGVTALVAALYLGARRGYPRNVMHPNNLVMTLMGAGL
LWVGWFGFNAGSAISSDLATARALTVTQMAAAAGAFTWMMVELVHYGKATSLGVASGILAGLVAITPAAGVVPPFGAFAL
GAIAALICYMAITLKNKLGYDDSLDAFGVHGVGGIVGALFLTFFIRPSWMAEAAEAAGGSWTVWQQLGVQATAVGVTVVF
AAVVSLVLLVIVEKTVGLRIGESDEMSGLDHSMHGEQGYGLINPN

Specific function: Involved in the uptake of ammonia [H]

COG id: COG0004

COG function: function code P; Ammonia permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ammonium transporter (TC 2.A.49) family [H]

Homologues:

Organism=Escherichia coli, GI1786656, Length=422, Percent_Identity=39.5734597156398, Blast_Score=272, Evalue=4e-74,
Organism=Caenorhabditis elegans, GI32564042, Length=416, Percent_Identity=27.4038461538462, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI133931100, Length=441, Percent_Identity=26.7573696145125, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17550180, Length=445, Percent_Identity=28.7640449438202, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17550182, Length=439, Percent_Identity=27.5626423690205, Blast_Score=126, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6325396, Length=420, Percent_Identity=32.6190476190476, Blast_Score=225, Evalue=1e-59,
Organism=Saccharomyces cerevisiae, GI6324187, Length=428, Percent_Identity=34.1121495327103, Blast_Score=223, Evalue=7e-59,
Organism=Saccharomyces cerevisiae, GI6321559, Length=435, Percent_Identity=30.5747126436782, Blast_Score=202, Evalue=8e-53,
Organism=Drosophila melanogaster, GI161078314, Length=410, Percent_Identity=31.4634146341463, Blast_Score=159, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001905
- InterPro:   IPR018047 [H]

Pfam domain/function: PF00909 Ammonium_transp [H]

EC number: NA

Molecular weight: Translated: 46788; Mature: 46788

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01219 AMMONIUM_TRANSP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFMGNKLRSSLLVLFALMMAHNTGWAAESVTSDTGTTSWMLTSTALVLLMVPGLAMFYGG
CCCCHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LVRTKNVLGTMMHSFAAMVIIGVIWPAVGYALSFGPNILGGLVGWNSDYFMLQGIDNAIM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEECCCHHHH
DSHIPEYVFAMFQGKFAIITPALIAGAFAERVNFKGYLLFIALWSIVVYTPICHWVWAAD
HCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
GFLFNLGAAGAIDFAGGTVVHISSGVTALVAALYLGARRGYPRNVMHPNNLVMTLMGAGL
CCEEECCCCCEEECCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCHH
LWVGWFGFNAGSAISSDLATARALTVTQMAAAAGAFTWMMVELVHYGKATSLGVASGILA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
GLVAITPAAGVVPPFGAFALGAIAALICYMAITLKNKLGYDDSLDAFGVHGVGGIVGALF
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
LTFFIRPSWMAEAAEAAGGSWTVWQQLGVQATAVGVTVVFAAVVSLVLLVIVEKTVGLRI
HHHHHCCHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
GESDEMSGLDHSMHGEQGYGLINPN
CCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFMGNKLRSSLLVLFALMMAHNTGWAAESVTSDTGTTSWMLTSTALVLLMVPGLAMFYGG
CCCCHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LVRTKNVLGTMMHSFAAMVIIGVIWPAVGYALSFGPNILGGLVGWNSDYFMLQGIDNAIM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEECCCHHHH
DSHIPEYVFAMFQGKFAIITPALIAGAFAERVNFKGYLLFIALWSIVVYTPICHWVWAAD
HCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
GFLFNLGAAGAIDFAGGTVVHISSGVTALVAALYLGARRGYPRNVMHPNNLVMTLMGAGL
CCEEECCCCCEEECCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCHH
LWVGWFGFNAGSAISSDLATARALTVTQMAAAAGAFTWMMVELVHYGKATSLGVASGILA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
GLVAITPAAGVVPPFGAFALGAIAALICYMAITLKNKLGYDDSLDAFGVHGVGGIVGALF
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
LTFFIRPSWMAEAAEAAGGSWTVWQQLGVQATAVGVTVVFAAVVSLVLLVIVEKTVGLRI
HHHHHCCHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
GESDEMSGLDHSMHGEQGYGLINPN
CCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NH3 [Periplasm] [C]

Specific reaction: NH3 [Periplasm] = NH3 [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]