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The map label for this gene is surA [H]

Identifier: 193211689

GI number: 193211689

Start: 16654

End: 17973

Strand: Direct

Name: surA [H]

Synonym: Cpar_0013

Alternate gene names: 193211689

Gene position: 16654-17973 (Clockwise)

Preceding gene: 193211688

Following gene: 193211693

Centisome position: 0.73

GC content: 55.45

Gene sequence:

>1320_bases
ATGAAAAAAACAGTCTTTGCTTTTTTTGCTGTTCTGATCGTCGCCCTTGCAGGTTTGTCGGATGCGATTGCTTCCAGCGC
TCCGGATAAAATCGTGGCCATTGTCGGTCGGGAGATCATTCTCAAATCCCAGATCAACGAACAGGAGCTGATGTACCATC
TTCAGTATCGCGAGTCTAAAAACGACCCCGGGCTGCGGCAGAAGATCCTGAAGAATATGATCGATCAGAAGATCCTTTTG
ACCAAAGCCCGGATCGACAGCATCAGTGTCAATGAGCAGGGTATCGATGAGATGGCGAACGCCAAATACAACGCGCTGCG
TTCGCAGTTTCCGTCAGTCAGCGCCATGGAGGAGCGGTTCAGCCTTCCGGTCAACCGGCTCAAGCAGGACATTCGTGACG
ACATCAGGAATCAGCAGATGGTGGACGCTCTCAGGCGGAAGCACTTTCATGATGTGACGGTCTCCTACGATGAGGTGATG
GCTTTCTACGGCAAGGAGCGGAACAACCTGCCAAAGGTGCCTGAAATGGTTTCGGTCTCCCAGCTCATCAGGTATCCGGA
GATTGCCGATAGCGAAAAGCAGCGGGCCATGAGCAAAATCCAGGCGATCAGCCAGCAGTTGCAGAATGGCGCTGATTTCG
CCACGCTTGCCCGCGAAACCTCCGATGACCCCGGTTCTCGCGAGCTTGGCGGTGACCTGGGCTTTGTCCACAAAGGCGAG
CTGGTGCCGAGCTTCGAGGAGGCGGCCTATGCGCTCAAGCCGGGACAGATTTCCGGTGTTGTCGAGAGCCGCTTCGGCTA
CCACCTGATCCAGCTGATCGACAAGGAGGATCAAAGCATTCATGTTCGGCACATTCTGGCCGCGTTTGATCGCAACAAGA
CCGATCTGCCCAAAACGGTTCGTATGCTGGAGGCCATCCGTGCCGACATTCTTGCCGGCAAGGCTTCGTTTGCCGAGATG
GCTGAAAAGTATTCGGAAGACCCTGCCTCCAAAGGTACTGGCGGTCAGGTCATCTCGAGCGCGACAGGAGAGCCCTTTTT
GGTGTTCGATTCACTGCGCCCTGATCTGCAGAAGATTGTCGGCGGGTTGAAGCATGCGGGCGACATAAGCCAGCCTGTGA
AGATCGAGCCGGAGCGCGGCCCCTTCTTCTATGCCCTGTTTAGGCTTGACGAAAGGCTTCCCGCGCACCAGTTGTCGCCG
GAGCGCGATTTCACCAGACTCGAAGAGATGGCGGCTAACCAGAAGCGTCAGGAGCAGTTCGAGGCCTGGATCGAGAAGCT
GAAGAAAGAGGTTGTGGTGCGGGTTATGTCAGACGTCTAA

Upstream 100 bases:

>100_bases
TTTGCTGAACAGGTTGTGGCCCCGCTTGCCGATGTATCGGGATGGAGGAGTGCCGCTTCGGAGCCCCATAGTCCGCTCAC
CACAAGAAAATTTCGATGTT

Downstream 100 bases:

>100_bases
GCGTCTGACATACTTGGCGTTCTGCTCGATGAAGTTGCGGCGGGGTTCGACCTTGTCGCCCATCAGCGTCGAGAAGACCT
GGTCGGCCTCCATAGCGTTT

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MKKTVFAFFAVLIVALAGLSDAIASSAPDKIVAIVGREIILKSQINEQELMYHLQYRESKNDPGLRQKILKNMIDQKILL
TKARIDSISVNEQGIDEMANAKYNALRSQFPSVSAMEERFSLPVNRLKQDIRDDIRNQQMVDALRRKHFHDVTVSYDEVM
AFYGKERNNLPKVPEMVSVSQLIRYPEIADSEKQRAMSKIQAISQQLQNGADFATLARETSDDPGSRELGGDLGFVHKGE
LVPSFEEAAYALKPGQISGVVESRFGYHLIQLIDKEDQSIHVRHILAAFDRNKTDLPKTVRMLEAIRADILAGKASFAEM
AEKYSEDPASKGTGGQVISSATGEPFLVFDSLRPDLQKIVGGLKHAGDISQPVKIEPERGPFFYALFRLDERLPAHQLSP
ERDFTRLEEMAANQKRQEQFEAWIEKLKKEVVVRVMSDV

Sequences:

>Translated_439_residues
MKKTVFAFFAVLIVALAGLSDAIASSAPDKIVAIVGREIILKSQINEQELMYHLQYRESKNDPGLRQKILKNMIDQKILL
TKARIDSISVNEQGIDEMANAKYNALRSQFPSVSAMEERFSLPVNRLKQDIRDDIRNQQMVDALRRKHFHDVTVSYDEVM
AFYGKERNNLPKVPEMVSVSQLIRYPEIADSEKQRAMSKIQAISQQLQNGADFATLARETSDDPGSRELGGDLGFVHKGE
LVPSFEEAAYALKPGQISGVVESRFGYHLIQLIDKEDQSIHVRHILAAFDRNKTDLPKTVRMLEAIRADILAGKASFAEM
AEKYSEDPASKGTGGQVISSATGEPFLVFDSLRPDLQKIVGGLKHAGDISQPVKIEPERGPFFYALFRLDERLPAHQLSP
ERDFTRLEEMAANQKRQEQFEAWIEKLKKEVVVRVMSDV
>Mature_439_residues
MKKTVFAFFAVLIVALAGLSDAIASSAPDKIVAIVGREIILKSQINEQELMYHLQYRESKNDPGLRQKILKNMIDQKILL
TKARIDSISVNEQGIDEMANAKYNALRSQFPSVSAMEERFSLPVNRLKQDIRDDIRNQQMVDALRRKHFHDVTVSYDEVM
AFYGKERNNLPKVPEMVSVSQLIRYPEIADSEKQRAMSKIQAISQQLQNGADFATLARETSDDPGSRELGGDLGFVHKGE
LVPSFEEAAYALKPGQISGVVESRFGYHLIQLIDKEDQSIHVRHILAAFDRNKTDLPKTVRMLEAIRADILAGKASFAEM
AEKYSEDPASKGTGGQVISSATGEPFLVFDSLRPDLQKIVGGLKHAGDISQPVKIEPERGPFFYALFRLDERLPAHQLSP
ERDFTRLEEMAANQKRQEQFEAWIEKLKKEVVVRVMSDV

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=398, Percent_Identity=28.1407035175879, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 49474; Mature: 49474

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTVFAFFAVLIVALAGLSDAIASSAPDKIVAIVGREIILKSQINEQELMYHLQYRESK
CCHHHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
NDPGLRQKILKNMIDQKILLTKARIDSISVNEQGIDEMANAKYNALRSQFPSVSAMEERF
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
SLPVNRLKQDIRDDIRNQQMVDALRRKHFHDVTVSYDEVMAFYGKERNNLPKVPEMVSVS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHH
QLIRYPEIADSEKQRAMSKIQAISQQLQNGADFATLARETSDDPGSRELGGDLGFVHKGE
HHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHCCCCCCCCCCC
LVPSFEEAAYALKPGQISGVVESRFGYHLIQLIDKEDQSIHVRHILAAFDRNKTDLPKTV
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHH
RMLEAIRADILAGKASFAEMAEKYSEDPASKGTGGQVISSATGEPFLVFDSLRPDLQKIV
HHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCEEEECCCCHHHHHHH
GGLKHAGDISQPVKIEPERGPFFYALFRLDERLPAHQLSPERDFTRLEEMAANQKRQEQF
HHHHHCCCCCCCCEECCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
EAWIEKLKKEVVVRVMSDV
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKTVFAFFAVLIVALAGLSDAIASSAPDKIVAIVGREIILKSQINEQELMYHLQYRESK
CCHHHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
NDPGLRQKILKNMIDQKILLTKARIDSISVNEQGIDEMANAKYNALRSQFPSVSAMEERF
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
SLPVNRLKQDIRDDIRNQQMVDALRRKHFHDVTVSYDEVMAFYGKERNNLPKVPEMVSVS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHH
QLIRYPEIADSEKQRAMSKIQAISQQLQNGADFATLARETSDDPGSRELGGDLGFVHKGE
HHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHCCCCCCCCCCC
LVPSFEEAAYALKPGQISGVVESRFGYHLIQLIDKEDQSIHVRHILAAFDRNKTDLPKTV
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHH
RMLEAIRADILAGKASFAEMAEKYSEDPASKGTGGQVISSATGEPFLVFDSLRPDLQKIV
HHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCEEEECCCCHHHHHHH
GGLKHAGDISQPVKIEPERGPFFYALFRLDERLPAHQLSPERDFTRLEEMAANQKRQEQF
HHHHHCCCCCCCCEECCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
EAWIEKLKKEVVVRVMSDV
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA