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The map label for this gene is ahpC [C]

Identifier: 192291100

GI number: 192291100

Start: 2952256

End: 2952885

Strand: Reverse

Name: ahpC [C]

Synonym: Rpal_2721

Alternate gene names: 192291100

Gene position: 2952885-2952256 (Counterclockwise)

Preceding gene: 192291101

Following gene: 192291099

Centisome position: 51.41

GC content: 61.43

Gene sequence:

>630_bases
ATGTCCCTTCATATCGGCGACATTGCCCCCGACTTCACCGCCGACACCACCAAGGGCAAGATTTCGTTCCACGACTTCAT
CGGCAACTCCTGGGTCTTCTTCTTCAGCCATCCGGCCGACTTCACCCCGGTCTGCACCACCGAGATGGGCAAGACCGCCA
AGCTGGCTCAGCCGTTCGCATCTCGGAACGTCAAGCCGATCGGCCTGTCGACCGACACCGTGGATGAGCACCTGAAGTGG
ATCGCGGACGTCAACGATACCCAGCAGACCGACCTGCAATTCCCGATCATCGCCGATCCGGAGCTGAAGGTCGCCAAGCT
GTACGACATGATCCATCCGAACCAGAGCGATACCGCCGCGGTGCGTTCGGTGTTCATCATCGATCCGAACAAGAAGATCC
GCCTCACCATGACCTACCCGATGAATGTCGGGCGGAACTTCGACGAGATCCTGCGCGTGATCGATGCGCTGCAGTTCGCC
GACAAGCACACCGTCGCGGCCCCGGCCGACTGGCGCCCGGGCGACAAGGTCATCATCCCGCTGTCGGTCAAAGGCGAAGC
CGCCACCAAGGCGTTCCCGCAGGGCTGGGAAGAACCCCGCCCCTATCTGCGCCTGACCACCATCAAGTAA

Upstream 100 bases:

>100_bases
CGGTGCGGAATCTCCATTTAGAAGGTCTCCATCCTTCCACGTGCACGACCTCGTTCGGCGCGTGACCCAGCACTCAACAA
ACGTACAGGAGACCGTACCG

Downstream 100 bases:

>100_bases
CTCGGCACGCGATCTGACGACGCCGGCGTTCGGTTCTCCCGGGCGCCGGCGTCGTTGCGTCGCACCGGCCTCAGGCCCTG
TCTGACCGGATCGTGTTCAC

Product: Peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MSLHIGDIAPDFTADTTKGKISFHDFIGNSWVFFFSHPADFTPVCTTEMGKTAKLAQPFASRNVKPIGLSTDTVDEHLKW
IADVNDTQQTDLQFPIIADPELKVAKLYDMIHPNQSDTAAVRSVFIIDPNKKIRLTMTYPMNVGRNFDEILRVIDALQFA
DKHTVAAPADWRPGDKVIIPLSVKGEAATKAFPQGWEEPRPYLRLTTIK

Sequences:

>Translated_209_residues
MSLHIGDIAPDFTADTTKGKISFHDFIGNSWVFFFSHPADFTPVCTTEMGKTAKLAQPFASRNVKPIGLSTDTVDEHLKW
IADVNDTQQTDLQFPIIADPELKVAKLYDMIHPNQSDTAAVRSVFIIDPNKKIRLTMTYPMNVGRNFDEILRVIDALQFA
DKHTVAAPADWRPGDKVIIPLSVKGEAATKAFPQGWEEPRPYLRLTTIK
>Mature_208_residues
SLHIGDIAPDFTADTTKGKISFHDFIGNSWVFFFSHPADFTPVCTTEMGKTAKLAQPFASRNVKPIGLSTDTVDEHLKWI
ADVNDTQQTDLQFPIIADPELKVAKLYDMIHPNQSDTAAVRSVFIIDPNKKIRLTMTYPMNVGRNFDEILRVIDALQFAD
KHTVAAPADWRPGDKVIIPLSVKGEAATKAFPQGWEEPRPYLRLTTIK

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=218, Percent_Identity=47.7064220183486, Blast_Score=200, Evalue=8e-52,
Organism=Homo sapiens, GI4505591, Length=182, Percent_Identity=35.1648351648352, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI32455266, Length=182, Percent_Identity=35.1648351648352, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI32455264, Length=182, Percent_Identity=35.1648351648352, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI32189392, Length=182, Percent_Identity=32.967032967033, Blast_Score=98, Evalue=5e-21,
Organism=Homo sapiens, GI5453549, Length=162, Percent_Identity=33.3333333333333, Blast_Score=94, Evalue=8e-20,
Organism=Homo sapiens, GI32483377, Length=175, Percent_Identity=30.8571428571429, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI5802974, Length=175, Percent_Identity=30.8571428571429, Blast_Score=86, Evalue=3e-17,
Organism=Escherichia coli, GI1786822, Length=151, Percent_Identity=29.1390728476821, Blast_Score=77, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI25153706, Length=203, Percent_Identity=37.4384236453202, Blast_Score=150, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI193204376, Length=181, Percent_Identity=34.8066298342541, Blast_Score=103, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI32565831, Length=181, Percent_Identity=34.8066298342541, Blast_Score=102, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17554494, Length=173, Percent_Identity=34.1040462427746, Blast_Score=98, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6319407, Length=214, Percent_Identity=52.803738317757, Blast_Score=212, Evalue=4e-56,
Organism=Saccharomyces cerevisiae, GI6323613, Length=185, Percent_Identity=29.1891891891892, Blast_Score=77, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320661, Length=162, Percent_Identity=29.6296296296296, Blast_Score=75, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24581278, Length=215, Percent_Identity=45.1162790697674, Blast_Score=196, Evalue=7e-51,
Organism=Drosophila melanogaster, GI24652434, Length=204, Percent_Identity=46.5686274509804, Blast_Score=187, Evalue=5e-48,
Organism=Drosophila melanogaster, GI17975518, Length=204, Percent_Identity=46.5686274509804, Blast_Score=186, Evalue=8e-48,
Organism=Drosophila melanogaster, GI24652436, Length=204, Percent_Identity=46.5686274509804, Blast_Score=186, Evalue=8e-48,
Organism=Drosophila melanogaster, GI17738015, Length=170, Percent_Identity=33.5294117647059, Blast_Score=100, Evalue=5e-22,
Organism=Drosophila melanogaster, GI21357347, Length=181, Percent_Identity=30.939226519337, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI17157991, Length=160, Percent_Identity=34.375, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24641739, Length=160, Percent_Identity=34.375, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24656348, Length=176, Percent_Identity=32.9545454545455, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI17864676, Length=176, Percent_Identity=32.9545454545455, Blast_Score=93, Evalue=1e-19,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 23411; Mature: 23280

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLHIGDIAPDFTADTTKGKISFHDFIGNSWVFFFSHPADFTPVCTTEMGKTAKLAQPFA
CEEECCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCEECCCCCCCHHHHCHHH
SRNVKPIGLSTDTVDEHLKWIADVNDTQQTDLQFPIIADPELKVAKLYDMIHPNQSDTAA
HCCCCEECCCCCCHHHHHHHHHCCCCCCCCCEECCEEECCCCHHHHHHHHHCCCCCCCCE
VRSVFIIDPNKKIRLTMTYPMNVGRNFDEILRVIDALQFADKHTVAAPADWRPGDKVIIP
EEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEECCCCCCCCCEEEEE
LSVKGEAATKAFPQGWEEPRPYLRLTTIK
EEECCCHHHHCCCCCCCCCCCEEEEEECC
>Mature Secondary Structure 
SLHIGDIAPDFTADTTKGKISFHDFIGNSWVFFFSHPADFTPVCTTEMGKTAKLAQPFA
EEECCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCEECCCCCCCHHHHCHHH
SRNVKPIGLSTDTVDEHLKWIADVNDTQQTDLQFPIIADPELKVAKLYDMIHPNQSDTAA
HCCCCEECCCCCCHHHHHHHHHCCCCCCCCCEECCEEECCCCHHHHHHHHHCCCCCCCCE
VRSVFIIDPNKKIRLTMTYPMNVGRNFDEILRVIDALQFADKHTVAAPADWRPGDKVIIP
EEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEECCCCCCCCCEEEEE
LSVKGEAATKAFPQGWEEPRPYLRLTTIK
EEECCCHHHHCCCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]